JP2020532589A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020532589A5 JP2020532589A5 JP2020534804A JP2020534804A JP2020532589A5 JP 2020532589 A5 JP2020532589 A5 JP 2020532589A5 JP 2020534804 A JP2020534804 A JP 2020534804A JP 2020534804 A JP2020534804 A JP 2020534804A JP 2020532589 A5 JP2020532589 A5 JP 2020532589A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrazine
- amino
- naphthalene
- imidazole
- methylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762553320P | 2017-09-01 | 2017-09-01 | |
| US62/553,320 | 2017-09-01 | ||
| PCT/US2018/049081 WO2019046711A2 (en) | 2017-09-01 | 2018-08-31 | COMPOUNDS AND COMPOSITIONS FOR INHIBITING IRE1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020532589A JP2020532589A (ja) | 2020-11-12 |
| JP2020532589A5 true JP2020532589A5 (OSRAM) | 2021-10-21 |
Family
ID=65526075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020534804A Pending JP2020532589A (ja) | 2017-09-01 | 2018-08-31 | Ｉｒｅ１阻害のための化合物および組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11649237B2 (OSRAM) |
| EP (1) | EP3675858B1 (OSRAM) |
| JP (1) | JP2020532589A (OSRAM) |
| KR (1) | KR20200066301A (OSRAM) |
| CN (1) | CN111526877B (OSRAM) |
| AU (1) | AU2018326721B2 (OSRAM) |
| BR (1) | BR112020004226A2 (OSRAM) |
| CA (1) | CA3074139A1 (OSRAM) |
| IL (1) | IL272845B2 (OSRAM) |
| MX (1) | MX2020002322A (OSRAM) |
| SG (1) | SG11202001609RA (OSRAM) |
| WO (1) | WO2019046711A2 (OSRAM) |
| ZA (1) | ZA202001320B (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7444458B2 (ja) * | 2018-09-21 | 2024-03-06 | 学校法人福岡大学 | プリオン病治療薬 |
| CA3131386A1 (en) * | 2019-02-27 | 2020-09-03 | Richard Keenan | Imidazolopyrazine compounds for ire1 inhibition |
| MX2021010345A (es) * | 2019-02-27 | 2021-12-15 | Optikira Llc | Compuestos de pirazolopiridina para la inhibición de ire1. |
| WO2022032078A1 (en) * | 2020-08-07 | 2022-02-10 | Optikira, LLC | Pyrazolopyridine compounds and methods of inhibiting ire1 using same |
| KR20230118855A (ko) * | 2020-11-13 | 2023-08-14 | 더 리전츠 오브 더 유니버시티 오브 캘리포니아 | IRE1α 억제제 및 이의 용도 |
| WO2023131677A1 (en) * | 2022-01-07 | 2023-07-13 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Compounds containing a hydroxyphenyl moiety and their use |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR057960A1 (es) * | 2005-12-02 | 2007-12-26 | Osi Pharm Inc | Inhibidores de proteina quinasa biciclicos |
| ES2396613T3 (es) | 2008-05-19 | 2013-02-22 | OSI Pharmaceuticals, LLC | Imidazopirazinas e imidazotriazinas sustituidas |
| WO2011047384A2 (en) * | 2009-10-16 | 2011-04-21 | The Regents Of The University Of California | Methods of inhibiting ire1 |
| ES2698048T3 (es) * | 2010-04-05 | 2019-01-30 | Fosun Orinove Pharmatech Inc | Inhibidores de IRE-1 |
| EP2548877A1 (en) * | 2011-07-19 | 2013-01-23 | MSD Oss B.V. | 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors |
| KR20150061651A (ko) * | 2012-09-26 | 2015-06-04 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | Ire1의 조절 |
| WO2016004254A1 (en) * | 2014-07-01 | 2016-01-07 | The Regents Of The University Of California | Combined modulation of ire1 |
| WO2017152126A1 (en) * | 2016-03-03 | 2017-09-08 | Cornell University | Small molecule ire1-alpha inhibitors |
| WO2018102751A1 (en) | 2016-12-02 | 2018-06-07 | Quentis Therapeutics, Inc. | Ire1 small molecule inhibitors |
-
2018
- 2018-08-31 US US16/642,208 patent/US11649237B2/en active Active
- 2018-08-31 CN CN201880066168.9A patent/CN111526877B/zh active Active
- 2018-08-31 KR KR1020207009201A patent/KR20200066301A/ko not_active Ceased
- 2018-08-31 BR BR112020004226-9A patent/BR112020004226A2/pt not_active Application Discontinuation
- 2018-08-31 WO PCT/US2018/049081 patent/WO2019046711A2/en not_active Ceased
- 2018-08-31 AU AU2018326721A patent/AU2018326721B2/en active Active
- 2018-08-31 CA CA3074139A patent/CA3074139A1/en active Pending
- 2018-08-31 EP EP18849820.8A patent/EP3675858B1/en active Active
- 2018-08-31 JP JP2020534804A patent/JP2020532589A/ja active Pending
- 2018-08-31 IL IL272845A patent/IL272845B2/en unknown
- 2018-08-31 SG SG11202001609RA patent/SG11202001609RA/en unknown
- 2018-08-31 MX MX2020002322A patent/MX2020002322A/es unknown
-
2020
- 2020-02-28 ZA ZA2020/01320A patent/ZA202001320B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020532589A5 (OSRAM) | ||
| IL272845B2 (en) | Compounds and preparations for inhibiting IRE1 | |
| RU2489426C2 (ru) | Производные аминопиразола | |
| JP2007519754A5 (OSRAM) | ||
| RU2455288C2 (ru) | Соединения и композиции 5-(4-(галогеналкокси)фенил)пиримидин-2-амина в качестве ингибиторов киназ | |
| JP2013530240A5 (OSRAM) | ||
| JP2014511869A5 (OSRAM) | ||
| JP2020506946A5 (OSRAM) | ||
| RU2017121044A (ru) | Производные амидотиадиазола в качестве ингибиторов надфн-оксидазы | |
| JP2013507350A5 (OSRAM) | ||
| JP2010540462A5 (OSRAM) | ||
| JP2020515575A5 (OSRAM) | ||
| JP2017537948A5 (OSRAM) | ||
| JP2007514003A5 (OSRAM) | ||
| JP2021501179A5 (OSRAM) | ||
| RU2012116877A (ru) | Соединения 2-пиридона, применяемые в качестве ингибиторов нейтрофильной эластазы | |
| JP2014508128A5 (OSRAM) | ||
| RU2013133800A (ru) | Селективные к bcl-2 агенты, вызывающие апоптоз, для лечения рака и иммунных заболеваний | |
| JP2012503018A5 (OSRAM) | ||
| JP2007531757A5 (OSRAM) | ||
| RU2011134631A (ru) | Вызывающие апоптоз средства для лечения рака и иммунных и аутоиммунных заболеваний | |
| JP2008502700A5 (OSRAM) | ||
| JP2018522823A5 (OSRAM) | ||
| JP2020516671A5 (OSRAM) | ||
| JP2013506637A5 (OSRAM) |