JP2020532534A5 - - Google Patents
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- Publication number
- JP2020532534A5 JP2020532534A5 JP2020512441A JP2020512441A JP2020532534A5 JP 2020532534 A5 JP2020532534 A5 JP 2020532534A5 JP 2020512441 A JP2020512441 A JP 2020512441A JP 2020512441 A JP2020512441 A JP 2020512441A JP 2020532534 A5 JP2020532534 A5 JP 2020532534A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- xaa
- sequence
- compound
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 25
- 229910052739 hydrogen Inorganic materials 0.000 claims 20
- 239000001257 hydrogen Substances 0.000 claims 20
- 150000002431 hydrogen Chemical group 0.000 claims 14
- 150000001413 amino acids Chemical class 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 125000000539 amino acid group Chemical group 0.000 claims 9
- 125000001931 aliphatic group Chemical group 0.000 claims 7
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 239000000863 peptide conjugate Substances 0.000 claims 4
- 125000006239 protecting group Chemical group 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 239000012453 solvate Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 3
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 2
- 101000831567 Homo sapiens Toll-like receptor 2 Proteins 0.000 claims 2
- 125000000729 N-terminal amino-acid group Chemical group 0.000 claims 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 2
- 102100024333 Toll-like receptor 2 Human genes 0.000 claims 2
- 230000003213 activating effect Effects 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 102100034411 H/ACA ribonucleoprotein complex subunit 2 Human genes 0.000 claims 1
- 101000994912 Homo sapiens H/ACA ribonucleoprotein complex subunit 2 Proteins 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 244000144980 herd Species 0.000 claims 1
- 125000003473 lipid group Chemical group 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 238000002255 vaccination Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ735008 | 2017-08-30 | ||
| NZ73500817 | 2017-08-30 | ||
| PCT/IB2018/056611 WO2019043604A1 (en) | 2017-08-30 | 2018-08-30 | PEPTIDE CONJUGATES, CONJUGATION METHOD, AND USES THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020532534A JP2020532534A (ja) | 2020-11-12 |
| JP2020532534A5 true JP2020532534A5 (enExample) | 2021-09-30 |
Family
ID=65526296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020512441A Pending JP2020532534A (ja) | 2017-08-30 | 2018-08-30 | ペプチド接合体、接合プロセス及びそれらの使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20200361864A1 (enExample) |
| EP (1) | EP3676250A4 (enExample) |
| JP (1) | JP2020532534A (enExample) |
| KR (1) | KR20200058424A (enExample) |
| CN (1) | CN111247123A (enExample) |
| AU (1) | AU2018323043A1 (enExample) |
| BR (1) | BR112020003907A2 (enExample) |
| CA (1) | CA3073314A1 (enExample) |
| EA (1) | EA202090319A1 (enExample) |
| IL (1) | IL272931A (enExample) |
| MX (1) | MX2020002084A (enExample) |
| SG (1) | SG11202001602QA (enExample) |
| TW (1) | TW201925240A (enExample) |
| WO (1) | WO2019043604A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012037612A1 (en) | 2010-09-22 | 2012-03-29 | The University Of Melbourne | Novel immunostimulatory method |
| PL3728289T3 (pl) | 2017-12-21 | 2026-01-26 | Axelia Oncology Pty Ltd | Zoptymalizowane związki |
| JP2022539091A (ja) | 2019-06-26 | 2022-09-07 | アクセリア オンコロジー ピーティーワイ リミテッド | 新規な分子 |
| CN110681362B (zh) * | 2019-09-26 | 2020-09-11 | 浙江大学 | 以羧基和吲哚基为功能基团的混合模式层析介质 |
| CN111349054A (zh) * | 2020-01-21 | 2020-06-30 | 青岛科技大学 | 一种防锈剂2-(1,3-苯并噻唑-2-硫基)丁二酸的制备方法 |
| AU2021294603A1 (en) * | 2020-06-26 | 2022-12-15 | Ena Respiratory Pty Ltd | Branched lipid compounds |
| WO2023028661A1 (en) * | 2021-09-02 | 2023-03-09 | Ena Respiratory Pty Ltd | Formulation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2390659C (en) * | 1999-11-15 | 2010-03-02 | Ludwig Institute For Cancer Research | Ny-eso-1 peptide derivatives, and uses thereof |
| WO2010028246A2 (en) * | 2008-09-05 | 2010-03-11 | Id Biomedical Corporation Of Quebec | Novel compositions and adjuvants |
| JP2012523379A (ja) * | 2009-04-09 | 2012-10-04 | ザ ユニバーシティー オブ メルボルン | 免疫原性組成物およびその使用 |
| CN105555756B (zh) * | 2013-06-28 | 2018-12-07 | 奥克兰联合服务有限公司 | 氨基酸缀合物和肽缀合物及缀合方法 |
| US11464853B2 (en) * | 2016-02-26 | 2022-10-11 | Auckland Uniservices Limited | Amino acid and peptide conjugates and conjugation process |
-
2018
- 2018-08-30 EA EA202090319A patent/EA202090319A1/ru unknown
- 2018-08-30 BR BR112020003907-1A patent/BR112020003907A2/pt not_active Application Discontinuation
- 2018-08-30 TW TW107130372A patent/TW201925240A/zh unknown
- 2018-08-30 WO PCT/IB2018/056611 patent/WO2019043604A1/en not_active Ceased
- 2018-08-30 CN CN201880055703.0A patent/CN111247123A/zh active Pending
- 2018-08-30 EP EP18850403.9A patent/EP3676250A4/en not_active Withdrawn
- 2018-08-30 SG SG11202001602QA patent/SG11202001602QA/en unknown
- 2018-08-30 JP JP2020512441A patent/JP2020532534A/ja active Pending
- 2018-08-30 CA CA3073314A patent/CA3073314A1/en active Pending
- 2018-08-30 MX MX2020002084A patent/MX2020002084A/es unknown
- 2018-08-30 AU AU2018323043A patent/AU2018323043A1/en not_active Abandoned
- 2018-08-30 US US16/638,185 patent/US20200361864A1/en not_active Abandoned
- 2018-08-30 KR KR1020207009057A patent/KR20200058424A/ko not_active Withdrawn
-
2020
- 2020-02-26 IL IL272931A patent/IL272931A/en unknown