JP2020531527A5 - - Google Patents
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- Publication number
- JP2020531527A5 JP2020531527A5 JP2020511325A JP2020511325A JP2020531527A5 JP 2020531527 A5 JP2020531527 A5 JP 2020531527A5 JP 2020511325 A JP2020511325 A JP 2020511325A JP 2020511325 A JP2020511325 A JP 2020511325A JP 2020531527 A5 JP2020531527 A5 JP 2020531527A5
- Authority
- JP
- Japan
- Prior art keywords
- patient
- rhasm
- acidic sphingomyelinase
- recombinant human
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 28
- 230000002378 acidificating effect Effects 0.000 claims 27
- 102000011971 Sphingomyelin Phosphodiesterase Human genes 0.000 claims 18
- 108010061312 Sphingomyelin Phosphodiesterase Proteins 0.000 claims 18
- 210000000988 bone and bone Anatomy 0.000 claims 17
- 208000007824 Type A Niemann-Pick Disease Diseases 0.000 claims 11
- 239000003814 drug Substances 0.000 claims 9
- 201000006935 Becker muscular dystrophy Diseases 0.000 claims 8
- 208000037663 Best vitelliform macular dystrophy Diseases 0.000 claims 8
- 229940079593 drug Drugs 0.000 claims 8
- 208000020938 vitelliform macular dystrophy 2 Diseases 0.000 claims 8
- 238000012423 maintenance Methods 0.000 claims 7
- 208000029725 Metabolic bone disease Diseases 0.000 claims 4
- 206010049088 Osteopenia Diseases 0.000 claims 4
- 208000001132 Osteoporosis Diseases 0.000 claims 4
- 210000001185 bone marrow Anatomy 0.000 claims 3
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000011707 mineral Substances 0.000 claims 3
- 229940122361 Bisphosphonate Drugs 0.000 claims 2
- 150000004663 bisphosphonates Chemical class 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 208000034030 Chronic neurovisceral acid sphingomyelinase deficiency Diseases 0.000 claims 1
- 208000035374 Chronic visceral acid sphingomyelinase deficiency Diseases 0.000 claims 1
- 201000000791 Niemann-Pick disease type B Diseases 0.000 claims 1
- 208000008291 Type B Niemann-Pick Disease Diseases 0.000 claims 1
- 230000002159 abnormal effect Effects 0.000 claims 1
- 230000005856 abnormality Effects 0.000 claims 1
- 230000007423 decrease Effects 0.000 claims 1
- 238000010253 intravenous injection Methods 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023005602A JP7431356B2 (ja) | 2017-08-24 | 2023-01-18 | 酸性スフィンゴミエリナーゼ欠損症患者における骨状態異常の処置 |
| JP2024012534A JP2024050732A (ja) | 2017-08-24 | 2024-01-31 | 酸性スフィンゴミエリナーゼ欠損症患者における骨状態異常の処置 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762549732P | 2017-08-24 | 2017-08-24 | |
| US62/549,732 | 2017-08-24 | ||
| EP17306720 | 2017-12-07 | ||
| EP17306720.8 | 2017-12-07 | ||
| PCT/IB2018/056346 WO2019038685A2 (en) | 2017-08-24 | 2018-08-22 | TREATMENT OF ABNORMAL BONE CONDITIONS IN PATIENTS WITH ACIDIC SPHINGOMYELASE DISEASE |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023005602A Division JP7431356B2 (ja) | 2017-08-24 | 2023-01-18 | 酸性スフィンゴミエリナーゼ欠損症患者における骨状態異常の処置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020531527A JP2020531527A (ja) | 2020-11-05 |
| JP2020531527A5 true JP2020531527A5 (https=) | 2021-09-30 |
| JP7216075B2 JP7216075B2 (ja) | 2023-01-31 |
Family
ID=63556374
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020511325A Active JP7216075B2 (ja) | 2017-08-24 | 2018-08-22 | 酸性スフィンゴミエリナーゼ欠損症患者における骨状態異常の処置 |
| JP2023005602A Active JP7431356B2 (ja) | 2017-08-24 | 2023-01-18 | 酸性スフィンゴミエリナーゼ欠損症患者における骨状態異常の処置 |
| JP2024012534A Pending JP2024050732A (ja) | 2017-08-24 | 2024-01-31 | 酸性スフィンゴミエリナーゼ欠損症患者における骨状態異常の処置 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023005602A Active JP7431356B2 (ja) | 2017-08-24 | 2023-01-18 | 酸性スフィンゴミエリナーゼ欠損症患者における骨状態異常の処置 |
| JP2024012534A Pending JP2024050732A (ja) | 2017-08-24 | 2024-01-31 | 酸性スフィンゴミエリナーゼ欠損症患者における骨状態異常の処置 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11898175B2 (https=) |
| EP (1) | EP3672622B1 (https=) |
| JP (3) | JP7216075B2 (https=) |
| KR (2) | KR20250025051A (https=) |
| CN (2) | CN111344003B (https=) |
| AU (2) | AU2018319565B2 (https=) |
| BR (1) | BR112020003541A2 (https=) |
| CA (1) | CA3073648A1 (https=) |
| CO (1) | CO2020001801A2 (https=) |
| ES (1) | ES2970423T3 (https=) |
| IL (1) | IL272757B2 (https=) |
| MX (2) | MX2020002106A (https=) |
| PL (1) | PL3672622T3 (https=) |
| SG (1) | SG11202001544VA (https=) |
| TW (1) | TWI791040B (https=) |
| WO (1) | WO2019038685A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3998078T1 (sl) * | 2009-08-28 | 2026-02-27 | Genzyme Corporation | Encimsko nadomestno zdravljenje z naraščajočim odmerkom za zdravljenje pomanjkanja kisle sfingomielinaze |
| KR20250025051A (ko) * | 2017-08-24 | 2025-02-20 | 사노피 | 산성 스핑고미엘린분해효소 결핍증 환자에서의 비정상적 골병태의 치료 |
| PY1939780A (es) * | 2018-05-25 | 2019-12-04 | Genzyme Corp | Composiciones farmacéuticas para el tratamiento de la deficiencia de esfingomielinasa ácida |
| EP3976218B1 (en) * | 2019-05-31 | 2025-02-19 | Genzyme Corporation | Two-dimensional lc-ms/ms systems |
| CN112773779B (zh) * | 2021-02-04 | 2022-08-16 | 上海交通大学医学院附属新华医院 | 氨溴索、千金藤和汉防已在治疗酸性鞘磷脂酶缺乏症中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5773278A (en) | 1991-05-03 | 1998-06-30 | Mount Sinai Medical Center | Acid sphingomyelinase gene |
| CN1302897A (zh) | 1999-10-28 | 2001-07-11 | 上海博容基因开发有限公司 | 一种新的多肽——人酸性鞘磷酯酶相似的磷酸二酯酶21和编码这种多肽的多核苷酸 |
| JP2008545752A (ja) * | 2005-06-02 | 2008-12-18 | テルシカ インコーポレーティッド | 成長障害を処置するための方法 |
| SI3998078T1 (sl) * | 2009-08-28 | 2026-02-27 | Genzyme Corporation | Encimsko nadomestno zdravljenje z naraščajočim odmerkom za zdravljenje pomanjkanja kisle sfingomielinaze |
| WO2013130963A1 (en) | 2012-03-02 | 2013-09-06 | Shire Human Genetic Therapies, Inc. | Compositions and methods for treating type iii gaucher disease |
| AR093908A1 (es) | 2012-12-12 | 2015-06-24 | Teva Pharma | Fusion de la hormona de crecimiento humana y albumina, formulacion y usos de la misma |
| LT3004896T (lt) * | 2013-06-07 | 2020-01-10 | Genzyme Corporation | Rūgštinės sfingomielinazės sutrikimų žymuo ir jo panaudojimas |
| KR20250025051A (ko) * | 2017-08-24 | 2025-02-20 | 사노피 | 산성 스핑고미엘린분해효소 결핍증 환자에서의 비정상적 골병태의 치료 |
-
2018
- 2018-08-22 KR KR1020257004704A patent/KR20250025051A/ko active Pending
- 2018-08-22 KR KR1020207008213A patent/KR102769578B1/ko active Active
- 2018-08-22 IL IL272757A patent/IL272757B2/en unknown
- 2018-08-22 CN CN201880067498.XA patent/CN111344003B/zh active Active
- 2018-08-22 BR BR112020003541-6A patent/BR112020003541A2/pt unknown
- 2018-08-22 JP JP2020511325A patent/JP7216075B2/ja active Active
- 2018-08-22 AU AU2018319565A patent/AU2018319565B2/en active Active
- 2018-08-22 SG SG11202001544VA patent/SG11202001544VA/en unknown
- 2018-08-22 US US16/641,116 patent/US11898175B2/en active Active
- 2018-08-22 EP EP18768948.4A patent/EP3672622B1/en active Active
- 2018-08-22 CA CA3073648A patent/CA3073648A1/en active Pending
- 2018-08-22 CN CN202410508209.2A patent/CN118453843A/zh active Pending
- 2018-08-22 TW TW107129257A patent/TWI791040B/zh active
- 2018-08-22 PL PL18768948.4T patent/PL3672622T3/pl unknown
- 2018-08-22 WO PCT/IB2018/056346 patent/WO2019038685A2/en not_active Ceased
- 2018-08-22 MX MX2020002106A patent/MX2020002106A/es unknown
- 2018-08-22 ES ES18768948T patent/ES2970423T3/es active Active
-
2020
- 2020-02-18 CO CONC2020/0001801A patent/CO2020001801A2/es unknown
- 2020-02-24 MX MX2023010908A patent/MX2023010908A/es unknown
-
2023
- 2023-01-18 JP JP2023005602A patent/JP7431356B2/ja active Active
-
2024
- 2024-01-10 US US18/409,535 patent/US20240218338A1/en not_active Abandoned
- 2024-01-31 JP JP2024012534A patent/JP2024050732A/ja active Pending
-
2025
- 2025-05-12 AU AU2025203384A patent/AU2025203384A1/en active Pending
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