SG11202001544VA - Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients - Google Patents

Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients

Info

Publication number
SG11202001544VA
SG11202001544VA SG11202001544VA SG11202001544VA SG11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA
Authority
SG
Singapore
Prior art keywords
treatment
abnormal bone
acid sphingomyelinase
bone conditions
sphingomyelinase deficiency
Prior art date
Application number
SG11202001544VA
Inventor
Ana Cristina Scheidt-Puga
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of SG11202001544VA publication Critical patent/SG11202001544VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/04Phosphoric diester hydrolases (3.1.4)
SG11202001544VA 2017-08-24 2018-08-22 Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients SG11202001544VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762549732P 2017-08-24 2017-08-24
EP17306720 2017-12-07
PCT/IB2018/056346 WO2019038685A2 (en) 2017-08-24 2018-08-22 Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients

Publications (1)

Publication Number Publication Date
SG11202001544VA true SG11202001544VA (en) 2020-03-30

Family

ID=63556374

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202001544VA SG11202001544VA (en) 2017-08-24 2018-08-22 Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients

Country Status (15)

Country Link
US (1) US11898175B2 (en)
EP (1) EP3672622B1 (en)
JP (3) JP7216075B2 (en)
KR (1) KR20200044064A (en)
CN (1) CN111344003A (en)
AU (1) AU2018319565A1 (en)
BR (1) BR112020003541A2 (en)
CA (1) CA3073648A1 (en)
CO (1) CO2020001801A2 (en)
IL (1) IL272757B1 (en)
MX (1) MX2020002106A (en)
PL (1) PL3672622T3 (en)
SG (1) SG11202001544VA (en)
TW (1) TWI791040B (en)
WO (1) WO2019038685A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY38238A (en) * 2018-05-25 2019-12-31 Genzyme Corp PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACID SPHINGOMYELINASE DEFICIENCY
KR20220016103A (en) * 2019-05-31 2022-02-08 젠자임 코포레이션 Two-dimensional LC-MS/MS system
CN112773779B (en) * 2021-02-04 2022-08-16 上海交通大学医学院附属新华医院 Application of ambroxol, stephania japonica and hanfang fang in treatment of acid sphingomyelinase deficiency

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773278A (en) 1991-05-03 1998-06-30 Mount Sinai Medical Center Acid sphingomyelinase gene
CN1302897A (en) 1999-10-28 2001-07-11 上海博容基因开发有限公司 Polypeptide-human phosphodiesterase 21 similar to acidic sphingomyelinase and polynucleotide for coding it
US8158582B2 (en) * 2005-06-02 2012-04-17 Tercica, Inc. Methods for treatment of insulin-like growth factor-1 deficiency
KR20230164773A (en) * 2009-08-28 2023-12-04 이칸 스쿨 오브 메디슨 엣 마운트 시나이 Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency
AU2013225816B2 (en) 2012-03-02 2017-10-26 Takeda Pharmaceutical Company Limited Compositions and methods for treating Type III Gaucher Disease
WO2014093354A1 (en) 2012-12-12 2014-06-19 Teva Pharmaceutical Industries Ltd. Fusion of human growth hormone and albumin, formulation and uses thereof
MY185990A (en) 2013-06-07 2021-06-14 Genzyme Corp Marker for acid sphingomyelinase disorders and uses thereof

Also Published As

Publication number Publication date
CO2020001801A2 (en) 2020-04-01
CA3073648A1 (en) 2019-02-28
KR20200044064A (en) 2020-04-28
EP3672622B1 (en) 2023-11-08
AU2018319565A1 (en) 2020-04-09
TWI791040B (en) 2023-02-01
WO2019038685A2 (en) 2019-02-28
US20210139868A1 (en) 2021-05-13
JP2024050732A (en) 2024-04-10
PL3672622T3 (en) 2024-04-02
JP7431356B2 (en) 2024-02-14
MX2020002106A (en) 2020-07-14
JP2023052459A (en) 2023-04-11
JP7216075B2 (en) 2023-01-31
RU2020111649A (en) 2021-09-24
WO2019038685A3 (en) 2019-05-02
JP2020531527A (en) 2020-11-05
BR112020003541A2 (en) 2020-09-01
TW201919689A (en) 2019-06-01
IL272757A (en) 2020-04-30
CN111344003A (en) 2020-06-26
US11898175B2 (en) 2024-02-13
IL272757B1 (en) 2024-03-01
EP3672622A2 (en) 2020-07-01

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