SG11202001544VA - Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients - Google Patents
Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patientsInfo
- Publication number
- SG11202001544VA SG11202001544VA SG11202001544VA SG11202001544VA SG11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- abnormal bone
- acid sphingomyelinase
- bone conditions
- sphingomyelinase deficiency
- Prior art date
Links
- 208000034012 Acid sphingomyelinase deficiency Diseases 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/04—Phosphoric diester hydrolases (3.1.4)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762549732P | 2017-08-24 | 2017-08-24 | |
EP17306720 | 2017-12-07 | ||
PCT/IB2018/056346 WO2019038685A2 (en) | 2017-08-24 | 2018-08-22 | Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202001544VA true SG11202001544VA (en) | 2020-03-30 |
Family
ID=63556374
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202001544VA SG11202001544VA (en) | 2017-08-24 | 2018-08-22 | Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients |
Country Status (15)
Country | Link |
---|---|
US (1) | US11898175B2 (en) |
EP (1) | EP3672622B1 (en) |
JP (3) | JP7216075B2 (en) |
KR (1) | KR20200044064A (en) |
CN (1) | CN111344003A (en) |
AU (1) | AU2018319565A1 (en) |
BR (1) | BR112020003541A2 (en) |
CA (1) | CA3073648A1 (en) |
CO (1) | CO2020001801A2 (en) |
IL (1) | IL272757B1 (en) |
MX (1) | MX2020002106A (en) |
PL (1) | PL3672622T3 (en) |
SG (1) | SG11202001544VA (en) |
TW (1) | TWI791040B (en) |
WO (1) | WO2019038685A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UY38238A (en) * | 2018-05-25 | 2019-12-31 | Genzyme Corp | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACID SPHINGOMYELINASE DEFICIENCY |
KR20220016103A (en) * | 2019-05-31 | 2022-02-08 | 젠자임 코포레이션 | Two-dimensional LC-MS/MS system |
CN112773779B (en) * | 2021-02-04 | 2022-08-16 | 上海交通大学医学院附属新华医院 | Application of ambroxol, stephania japonica and hanfang fang in treatment of acid sphingomyelinase deficiency |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5773278A (en) | 1991-05-03 | 1998-06-30 | Mount Sinai Medical Center | Acid sphingomyelinase gene |
CN1302897A (en) | 1999-10-28 | 2001-07-11 | 上海博容基因开发有限公司 | Polypeptide-human phosphodiesterase 21 similar to acidic sphingomyelinase and polynucleotide for coding it |
US8158582B2 (en) * | 2005-06-02 | 2012-04-17 | Tercica, Inc. | Methods for treatment of insulin-like growth factor-1 deficiency |
KR20230164773A (en) * | 2009-08-28 | 2023-12-04 | 이칸 스쿨 오브 메디슨 엣 마운트 시나이 | Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency |
AU2013225816B2 (en) | 2012-03-02 | 2017-10-26 | Takeda Pharmaceutical Company Limited | Compositions and methods for treating Type III Gaucher Disease |
WO2014093354A1 (en) | 2012-12-12 | 2014-06-19 | Teva Pharmaceutical Industries Ltd. | Fusion of human growth hormone and albumin, formulation and uses thereof |
MY185990A (en) | 2013-06-07 | 2021-06-14 | Genzyme Corp | Marker for acid sphingomyelinase disorders and uses thereof |
-
2018
- 2018-08-22 MX MX2020002106A patent/MX2020002106A/en unknown
- 2018-08-22 CN CN201880067498.XA patent/CN111344003A/en active Pending
- 2018-08-22 IL IL272757A patent/IL272757B1/en unknown
- 2018-08-22 JP JP2020511325A patent/JP7216075B2/en active Active
- 2018-08-22 TW TW107129257A patent/TWI791040B/en active
- 2018-08-22 CA CA3073648A patent/CA3073648A1/en active Pending
- 2018-08-22 KR KR1020207008213A patent/KR20200044064A/en not_active Application Discontinuation
- 2018-08-22 AU AU2018319565A patent/AU2018319565A1/en active Pending
- 2018-08-22 WO PCT/IB2018/056346 patent/WO2019038685A2/en active Application Filing
- 2018-08-22 SG SG11202001544VA patent/SG11202001544VA/en unknown
- 2018-08-22 PL PL18768948.4T patent/PL3672622T3/en unknown
- 2018-08-22 EP EP18768948.4A patent/EP3672622B1/en active Active
- 2018-08-22 BR BR112020003541-6A patent/BR112020003541A2/en unknown
- 2018-08-22 US US16/641,116 patent/US11898175B2/en active Active
-
2020
- 2020-02-18 CO CONC2020/0001801A patent/CO2020001801A2/en unknown
-
2023
- 2023-01-18 JP JP2023005602A patent/JP7431356B2/en active Active
-
2024
- 2024-01-31 JP JP2024012534A patent/JP2024050732A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CO2020001801A2 (en) | 2020-04-01 |
CA3073648A1 (en) | 2019-02-28 |
KR20200044064A (en) | 2020-04-28 |
EP3672622B1 (en) | 2023-11-08 |
AU2018319565A1 (en) | 2020-04-09 |
TWI791040B (en) | 2023-02-01 |
WO2019038685A2 (en) | 2019-02-28 |
US20210139868A1 (en) | 2021-05-13 |
JP2024050732A (en) | 2024-04-10 |
PL3672622T3 (en) | 2024-04-02 |
JP7431356B2 (en) | 2024-02-14 |
MX2020002106A (en) | 2020-07-14 |
JP2023052459A (en) | 2023-04-11 |
JP7216075B2 (en) | 2023-01-31 |
RU2020111649A (en) | 2021-09-24 |
WO2019038685A3 (en) | 2019-05-02 |
JP2020531527A (en) | 2020-11-05 |
BR112020003541A2 (en) | 2020-09-01 |
TW201919689A (en) | 2019-06-01 |
IL272757A (en) | 2020-04-30 |
CN111344003A (en) | 2020-06-26 |
US11898175B2 (en) | 2024-02-13 |
IL272757B1 (en) | 2024-03-01 |
EP3672622A2 (en) | 2020-07-01 |
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