PL3672622T3 - Rekombinowana ludzka kwaśna sfingomielinaza do zastosowania w leczeniu nieprawidłowych stanów kości u pacjentów z niedoborem kwaśnej sfingomielinazy - Google Patents
Rekombinowana ludzka kwaśna sfingomielinaza do zastosowania w leczeniu nieprawidłowych stanów kości u pacjentów z niedoborem kwaśnej sfingomielinazyInfo
- Publication number
- PL3672622T3 PL3672622T3 PL18768948.4T PL18768948T PL3672622T3 PL 3672622 T3 PL3672622 T3 PL 3672622T3 PL 18768948 T PL18768948 T PL 18768948T PL 3672622 T3 PL3672622 T3 PL 3672622T3
- Authority
- PL
- Poland
- Prior art keywords
- acid sphingomyelinase
- recombinant human
- abnormal bone
- treating abnormal
- bone conditions
- Prior art date
Links
- 208000034012 Acid sphingomyelinase deficiency Diseases 0.000 title 1
- 101000785978 Homo sapiens Sphingomyelin phosphodiesterase Proteins 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 title 1
- 102000048866 human SMPD1 Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/04—Phosphoric diester hydrolases (3.1.4)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762549732P | 2017-08-24 | 2017-08-24 | |
| EP17306720 | 2017-12-07 | ||
| PCT/IB2018/056346 WO2019038685A2 (en) | 2017-08-24 | 2018-08-22 | TREATMENT OF ABNORMAL BONE CONDITIONS IN PATIENTS WITH ACIDIC SPHINGOMYELASE DISEASE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3672622T3 true PL3672622T3 (pl) | 2024-04-02 |
Family
ID=63556374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18768948.4T PL3672622T3 (pl) | 2017-08-24 | 2018-08-22 | Rekombinowana ludzka kwaśna sfingomielinaza do zastosowania w leczeniu nieprawidłowych stanów kości u pacjentów z niedoborem kwaśnej sfingomielinazy |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11898175B2 (pl) |
| EP (1) | EP3672622B1 (pl) |
| JP (3) | JP7216075B2 (pl) |
| KR (1) | KR20200044064A (pl) |
| CN (2) | CN118453843A (pl) |
| AU (1) | AU2018319565A1 (pl) |
| BR (1) | BR112020003541A2 (pl) |
| CA (1) | CA3073648A1 (pl) |
| CO (1) | CO2020001801A2 (pl) |
| ES (1) | ES2970423T3 (pl) |
| IL (1) | IL272757B2 (pl) |
| MX (2) | MX2020002106A (pl) |
| PL (1) | PL3672622T3 (pl) |
| SG (1) | SG11202001544VA (pl) |
| TW (1) | TWI791040B (pl) |
| WO (1) | WO2019038685A2 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY38238A (es) * | 2018-05-25 | 2019-12-31 | Genzyme Corp | Composiciones farmacéuticas para el tratamiento de la deficiencia de esfingomielinasa ácida |
| CA3140183A1 (en) * | 2019-05-31 | 2020-12-03 | Genzyme Corporation | Two-dimensional lc-ms/ms systems |
| CN112773779B (zh) * | 2021-02-04 | 2022-08-16 | 上海交通大学医学院附属新华医院 | 氨溴索、千金藤和汉防已在治疗酸性鞘磷脂酶缺乏症中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5773278A (en) | 1991-05-03 | 1998-06-30 | Mount Sinai Medical Center | Acid sphingomyelinase gene |
| CN1302897A (zh) | 1999-10-28 | 2001-07-11 | 上海博容基因开发有限公司 | 一种新的多肽——人酸性鞘磷酯酶相似的磷酸二酯酶21和编码这种多肽的多核苷酸 |
| US8158582B2 (en) * | 2005-06-02 | 2012-04-17 | Tercica, Inc. | Methods for treatment of insulin-like growth factor-1 deficiency |
| DK2470199T3 (da) | 2009-08-28 | 2019-08-05 | Icahn School Med Mount Sinai | Dosisoptrapning enzymerstatningsterapi til behandling af mangel på sur sphingomyelinase |
| MX361231B (es) | 2012-03-02 | 2018-11-30 | Shire Human Genetic Therapies | Composiciones y usos de las mismas para tratar la enfermedad de gaucher tipo iii. |
| MX2015007402A (es) | 2012-12-12 | 2015-09-23 | Teva Pharma | Fusion de hormona de crecimiento humano y albumina, formulacion y usos de los mismos. |
| KR102292298B1 (ko) | 2013-06-07 | 2021-08-24 | 젠자임 코포레이션 | 산 스핑고미엘리나제 장애에 대한 마커 및 이의 용도 |
-
2018
- 2018-08-22 CN CN202410508209.2A patent/CN118453843A/zh active Pending
- 2018-08-22 EP EP18768948.4A patent/EP3672622B1/en active Active
- 2018-08-22 US US16/641,116 patent/US11898175B2/en active Active
- 2018-08-22 CN CN201880067498.XA patent/CN111344003B/zh active Active
- 2018-08-22 BR BR112020003541-6A patent/BR112020003541A2/pt unknown
- 2018-08-22 IL IL272757A patent/IL272757B2/en unknown
- 2018-08-22 MX MX2020002106A patent/MX2020002106A/es unknown
- 2018-08-22 WO PCT/IB2018/056346 patent/WO2019038685A2/en active Application Filing
- 2018-08-22 SG SG11202001544VA patent/SG11202001544VA/en unknown
- 2018-08-22 AU AU2018319565A patent/AU2018319565A1/en active Pending
- 2018-08-22 CA CA3073648A patent/CA3073648A1/en active Pending
- 2018-08-22 JP JP2020511325A patent/JP7216075B2/ja active Active
- 2018-08-22 PL PL18768948.4T patent/PL3672622T3/pl unknown
- 2018-08-22 KR KR1020207008213A patent/KR20200044064A/ko not_active Application Discontinuation
- 2018-08-22 ES ES18768948T patent/ES2970423T3/es active Active
- 2018-08-22 TW TW107129257A patent/TWI791040B/zh active
-
2020
- 2020-02-18 CO CONC2020/0001801A patent/CO2020001801A2/es unknown
- 2020-02-24 MX MX2023010908A patent/MX2023010908A/es unknown
-
2023
- 2023-01-18 JP JP2023005602A patent/JP7431356B2/ja active Active
-
2024
- 2024-01-10 US US18/409,535 patent/US20240218338A1/en active Pending
- 2024-01-31 JP JP2024012534A patent/JP2024050732A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL272757A (en) | 2020-04-30 |
| CN111344003A (zh) | 2020-06-26 |
| JP2020531527A (ja) | 2020-11-05 |
| IL272757B2 (en) | 2024-07-01 |
| US11898175B2 (en) | 2024-02-13 |
| TW201919689A (zh) | 2019-06-01 |
| SG11202001544VA (en) | 2020-03-30 |
| CA3073648A1 (en) | 2019-02-28 |
| MX2023010908A (es) | 2023-09-27 |
| WO2019038685A3 (en) | 2019-05-02 |
| CN118453843A (zh) | 2024-08-09 |
| EP3672622A2 (en) | 2020-07-01 |
| ES2970423T3 (es) | 2024-05-28 |
| IL272757B1 (en) | 2024-03-01 |
| EP3672622B1 (en) | 2023-11-08 |
| AU2018319565A1 (en) | 2020-04-09 |
| CN111344003B (zh) | 2024-05-07 |
| KR20200044064A (ko) | 2020-04-28 |
| JP7216075B2 (ja) | 2023-01-31 |
| MX2020002106A (es) | 2020-07-14 |
| RU2020111649A (ru) | 2021-09-24 |
| CO2020001801A2 (es) | 2020-04-01 |
| BR112020003541A2 (pt) | 2020-09-01 |
| JP2023052459A (ja) | 2023-04-11 |
| WO2019038685A2 (en) | 2019-02-28 |
| US20210139868A1 (en) | 2021-05-13 |
| TWI791040B (zh) | 2023-02-01 |
| JP7431356B2 (ja) | 2024-02-14 |
| JP2024050732A (ja) | 2024-04-10 |
| US20240218338A1 (en) | 2024-07-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1246625A1 (zh) | 用於熱療法的改進的醫療墊和系統 | |
| IL261063A (en) | Fixing staples for use in surgical procedures | |
| HK1247838A1 (zh) | 骨質疏鬆症的治療 | |
| EP3823569C0 (en) | INTEGRATED SURGICAL SYSTEM FOR TREATING THE IRIDOCORNEAL ANGLE OF THE EYE | |
| HK1250494A1 (zh) | 用於神經再生的生物相容性植入物及其使用方法 | |
| EP3166487A4 (en) | Bone reconstruction and orthopedic implants | |
| IN2014DN08676A (pl) | ||
| IL264301A (en) | Treatment of Fabry disease in ert-naive and ert-experienced patients | |
| IL272757A (en) | Treatment of abnormal bone condition in patients with sphingomyelin deficiency | |
| IL270530A (en) | Recombinant human acid alpha-glucosidase | |
| SG11202000423XA (en) | Treatment of fabry disease in ert-naïve and ert-experienced patients | |
| PL3294279T3 (pl) | Kompozycje zawierające aminokwasy do zastosowania w leczeniu zapalenia błony śluzowej u pacjentów cierpiących na neoplazję poddawanych radioterapii i/lub chemioterapii | |
| EP3253886A4 (en) | Novel methods for early identification of bone healing ability in injured patients | |
| EP3310282C0 (fr) | Implant pour la fixation d'éléments osseux | |
| IL273470A (en) | Semaglutide in medical treatment | |
| GB201519557D0 (en) | Compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions | |
| GB201503967D0 (en) | Biocompatible implants for use in tendon therapy | |
| EP3518951C0 (en) | COMPOSITIONS FOR USE IN THE TREATMENT OF OSTEOPOROSIS AND Fractures | |
| IL228155A0 (en) | Orthopedic implant for the treatment of bone deformities | |
| EP2984999A4 (en) | LOCALLY INVASIVE SURGICAL APPARATUS WITH A MANIPULATOR FOR TREATING BONE OBESE | |
| GB201812041D0 (en) | Surgical implants and apparatus for use in surgery | |
| IL288307A (en) | Preparations for use in the treatment of insulin deficiency conditions | |
| PT3672622T (pt) | Esfingomielinase ácida humana recombinante para utlização no tratamento de condições ósseas anormais em pacientes com deficiência de esfingomielinase ácida | |
| MX2020012700A (es) | Composiciones farmaceuticas para el tratamiento de la deficiencia de esfingomielinasa acida. | |
| GB201521442D0 (en) | Polytpeptides and analogues thereof for use in the treatment of diabetes and bone disorders |