SG11202001544VA - Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients - Google Patents
Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patientsInfo
- Publication number
- SG11202001544VA SG11202001544VA SG11202001544VA SG11202001544VA SG11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- abnormal bone
- acid sphingomyelinase
- bone conditions
- sphingomyelinase deficiency
- Prior art date
Links
- 208000034012 Acid sphingomyelinase deficiency Diseases 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 title 1
- 210000000988 bone and bone Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/04—Phosphoric diester hydrolases (3.1.4)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762549732P | 2017-08-24 | 2017-08-24 | |
| EP17306720 | 2017-12-07 | ||
| PCT/IB2018/056346 WO2019038685A2 (en) | 2017-08-24 | 2018-08-22 | TREATMENT OF ABNORMAL BONE CONDITIONS IN PATIENTS WITH ACIDIC SPHINGOMYELASE DISEASE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202001544VA true SG11202001544VA (en) | 2020-03-30 |
Family
ID=63556374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202001544VA SG11202001544VA (en) | 2017-08-24 | 2018-08-22 | Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11898175B2 (https=) |
| EP (1) | EP3672622B1 (https=) |
| JP (3) | JP7216075B2 (https=) |
| KR (2) | KR20250025051A (https=) |
| CN (2) | CN111344003B (https=) |
| AU (2) | AU2018319565B2 (https=) |
| BR (1) | BR112020003541A2 (https=) |
| CA (1) | CA3073648A1 (https=) |
| CO (1) | CO2020001801A2 (https=) |
| ES (1) | ES2970423T3 (https=) |
| IL (1) | IL272757B2 (https=) |
| MX (2) | MX2020002106A (https=) |
| PL (1) | PL3672622T3 (https=) |
| SG (1) | SG11202001544VA (https=) |
| TW (1) | TWI791040B (https=) |
| WO (1) | WO2019038685A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3998078T1 (sl) * | 2009-08-28 | 2026-02-27 | Genzyme Corporation | Encimsko nadomestno zdravljenje z naraščajočim odmerkom za zdravljenje pomanjkanja kisle sfingomielinaze |
| KR20250025051A (ko) * | 2017-08-24 | 2025-02-20 | 사노피 | 산성 스핑고미엘린분해효소 결핍증 환자에서의 비정상적 골병태의 치료 |
| PY1939780A (es) * | 2018-05-25 | 2019-12-04 | Genzyme Corp | Composiciones farmacéuticas para el tratamiento de la deficiencia de esfingomielinasa ácida |
| EP3976218B1 (en) * | 2019-05-31 | 2025-02-19 | Genzyme Corporation | Two-dimensional lc-ms/ms systems |
| CN112773779B (zh) * | 2021-02-04 | 2022-08-16 | 上海交通大学医学院附属新华医院 | 氨溴索、千金藤和汉防已在治疗酸性鞘磷脂酶缺乏症中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5773278A (en) | 1991-05-03 | 1998-06-30 | Mount Sinai Medical Center | Acid sphingomyelinase gene |
| CN1302897A (zh) | 1999-10-28 | 2001-07-11 | 上海博容基因开发有限公司 | 一种新的多肽——人酸性鞘磷酯酶相似的磷酸二酯酶21和编码这种多肽的多核苷酸 |
| JP2008545752A (ja) * | 2005-06-02 | 2008-12-18 | テルシカ インコーポレーティッド | 成長障害を処置するための方法 |
| SI3998078T1 (sl) * | 2009-08-28 | 2026-02-27 | Genzyme Corporation | Encimsko nadomestno zdravljenje z naraščajočim odmerkom za zdravljenje pomanjkanja kisle sfingomielinaze |
| WO2013130963A1 (en) | 2012-03-02 | 2013-09-06 | Shire Human Genetic Therapies, Inc. | Compositions and methods for treating type iii gaucher disease |
| AR093908A1 (es) | 2012-12-12 | 2015-06-24 | Teva Pharma | Fusion de la hormona de crecimiento humana y albumina, formulacion y usos de la misma |
| LT3004896T (lt) * | 2013-06-07 | 2020-01-10 | Genzyme Corporation | Rūgštinės sfingomielinazės sutrikimų žymuo ir jo panaudojimas |
| KR20250025051A (ko) * | 2017-08-24 | 2025-02-20 | 사노피 | 산성 스핑고미엘린분해효소 결핍증 환자에서의 비정상적 골병태의 치료 |
-
2018
- 2018-08-22 KR KR1020257004704A patent/KR20250025051A/ko active Pending
- 2018-08-22 KR KR1020207008213A patent/KR102769578B1/ko active Active
- 2018-08-22 IL IL272757A patent/IL272757B2/en unknown
- 2018-08-22 CN CN201880067498.XA patent/CN111344003B/zh active Active
- 2018-08-22 BR BR112020003541-6A patent/BR112020003541A2/pt unknown
- 2018-08-22 JP JP2020511325A patent/JP7216075B2/ja active Active
- 2018-08-22 AU AU2018319565A patent/AU2018319565B2/en active Active
- 2018-08-22 SG SG11202001544VA patent/SG11202001544VA/en unknown
- 2018-08-22 US US16/641,116 patent/US11898175B2/en active Active
- 2018-08-22 EP EP18768948.4A patent/EP3672622B1/en active Active
- 2018-08-22 CA CA3073648A patent/CA3073648A1/en active Pending
- 2018-08-22 CN CN202410508209.2A patent/CN118453843A/zh active Pending
- 2018-08-22 TW TW107129257A patent/TWI791040B/zh active
- 2018-08-22 PL PL18768948.4T patent/PL3672622T3/pl unknown
- 2018-08-22 WO PCT/IB2018/056346 patent/WO2019038685A2/en not_active Ceased
- 2018-08-22 MX MX2020002106A patent/MX2020002106A/es unknown
- 2018-08-22 ES ES18768948T patent/ES2970423T3/es active Active
-
2020
- 2020-02-18 CO CONC2020/0001801A patent/CO2020001801A2/es unknown
- 2020-02-24 MX MX2023010908A patent/MX2023010908A/es unknown
-
2023
- 2023-01-18 JP JP2023005602A patent/JP7431356B2/ja active Active
-
2024
- 2024-01-10 US US18/409,535 patent/US20240218338A1/en not_active Abandoned
- 2024-01-31 JP JP2024012534A patent/JP2024050732A/ja active Pending
-
2025
- 2025-05-12 AU AU2025203384A patent/AU2025203384A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL272757A (en) | Treatment of abnormal bone condition in patients with sphingomyelin deficiency | |
| EP3256152A4 (en) | Treatment of bone fractures and defects | |
| IL264301A (en) | Treatment of Fabry disease in ert-naive and ert-experienced patients | |
| EP3680856C0 (en) | ASSESSMENT OF DENTAL TREATMENTS AND PROCEDURES BASED ON PHOTOGRAPHS | |
| DK2861246T3 (en) | Compositions and Methods of Inhibiting MASP-1 and/or MASP-2 and/or MASP-3 for the Treatment of Various Diseases and Disorders | |
| PL3283137T3 (pl) | Biozgodne implanty do regeneracji nerwu i sposoby ich stosowania | |
| PL3253443T3 (pl) | Urządzenie do leczenia chrapania i bezdechu sennego | |
| EP3166487A4 (en) | Bone reconstruction and orthopedic implants | |
| SG11201700935VA (en) | Medical/surgical implant | |
| IL266772B (en) | Prevention and treatment of bone and cartilage damage or disease | |
| EP3253886A4 (en) | Novel methods for early identification of bone healing ability in injured patients | |
| SG11202000423XA (en) | Treatment of fabry disease in ert-naïve and ert-experienced patients | |
| IL250662A0 (en) | Tissue protection devices for the treatment of heart failure and other conditions | |
| GB201503967D0 (en) | Biocompatible implants for use in tendon therapy | |
| GB201519557D0 (en) | Compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions | |
| IL228155B (en) | Orthopedic implant for the treatment of bone deformities | |
| IL237117A0 (en) | Dental implant for stabilization and ease of insertion into the implantation site | |
| PL3182980T3 (pl) | Leczenie chorób niedoboru glikozylacji | |
| GB202213340D0 (en) | Stem cell line for treatment of various medical conditions | |
| IL257935A (en) | Treatment of bone growth disorders | |
| PT3672622T (pt) | Esfingomielinase ácida humana recombinante para utlização no tratamento de condições ósseas anormais em pacientes com deficiência de esfingomielinase ácida | |
| GB201403899D0 (en) | Synergistic composition comprising quercetin and polyphosphate for treatment of bone disorders | |
| SMT202500016T1 (it) | Trattamento di pazienti affetti da malattia di fabry aventi determinate mutazioni | |
| PL3148468T3 (pl) | Urządzenie do stymulacji i/lub leczenia tkanek anatomicznych | |
| IL247369A0 (en) | Compounds and methods for the treatment of bone diseases |