JP2020529996A5 - - Google Patents
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- JP2020529996A5 JP2020529996A5 JP2020505487A JP2020505487A JP2020529996A5 JP 2020529996 A5 JP2020529996 A5 JP 2020529996A5 JP 2020505487 A JP2020505487 A JP 2020505487A JP 2020505487 A JP2020505487 A JP 2020505487A JP 2020529996 A5 JP2020529996 A5 JP 2020529996A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- individual
- daily dose
- plasma concentration
- agent according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023014110A JP2023065372A (ja) | 2017-08-04 | 2023-02-01 | 肥大型心筋症の治療で使用するためのマバカムテン |
| JP2024192836A JP2025020292A (ja) | 2017-08-04 | 2024-11-01 | 肥大型心筋症の治療で使用するためのマバカムテン |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762541591P | 2017-08-04 | 2017-08-04 | |
| US62/541,591 | 2017-08-04 | ||
| US201762584537P | 2017-11-10 | 2017-11-10 | |
| US62/584,537 | 2017-11-10 | ||
| US201862639922P | 2018-03-07 | 2018-03-07 | |
| US62/639,922 | 2018-03-07 | ||
| US201862671585P | 2018-05-15 | 2018-05-15 | |
| US62/671,585 | 2018-05-15 | ||
| PCT/US2018/045180 WO2019028360A1 (en) | 2017-08-04 | 2018-08-03 | MAVACAMTEN FOR USE IN THE TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023014110A Division JP2023065372A (ja) | 2017-08-04 | 2023-02-01 | 肥大型心筋症の治療で使用するためのマバカムテン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020529996A JP2020529996A (ja) | 2020-10-15 |
| JP2020529996A5 true JP2020529996A5 (enExample) | 2021-10-07 |
Family
ID=63350605
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020505487A Pending JP2020529996A (ja) | 2017-08-04 | 2018-08-03 | 肥大型心筋症の治療で使用するためのマバカムテン |
| JP2023014110A Pending JP2023065372A (ja) | 2017-08-04 | 2023-02-01 | 肥大型心筋症の治療で使用するためのマバカムテン |
| JP2024192836A Pending JP2025020292A (ja) | 2017-08-04 | 2024-11-01 | 肥大型心筋症の治療で使用するためのマバカムテン |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023014110A Pending JP2023065372A (ja) | 2017-08-04 | 2023-02-01 | 肥大型心筋症の治療で使用するためのマバカムテン |
| JP2024192836A Pending JP2025020292A (ja) | 2017-08-04 | 2024-11-01 | 肥大型心筋症の治療で使用するためのマバカムテン |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US20200054636A1 (enExample) |
| EP (2) | EP3661514B1 (enExample) |
| JP (3) | JP2020529996A (enExample) |
| KR (2) | KR20250116181A (enExample) |
| CN (2) | CN111182901A (enExample) |
| AU (2) | AU2018311974B2 (enExample) |
| CA (1) | CA3071948A1 (enExample) |
| IL (2) | IL322175A (enExample) |
| LT (1) | LT3661514T (enExample) |
| MA (1) | MA49760A (enExample) |
| MX (3) | MX2020001406A (enExample) |
| MY (1) | MY208231A (enExample) |
| RU (1) | RU2020109345A (enExample) |
| SG (2) | SG10202112960QA (enExample) |
| SM (1) | SMT202500413T1 (enExample) |
| UY (1) | UY37834A (enExample) |
| WO (1) | WO2019028360A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI835770B (zh) | 2018-01-19 | 2024-03-21 | 美商胞質動力學公司 | 心肌節抑制劑 |
| JP7438148B2 (ja) | 2018-06-26 | 2024-02-26 | サイトキネティックス， インコーポレイテッド | 心臓サルコメア阻害剤 |
| US12187712B2 (en) | 2018-06-26 | 2025-01-07 | Cytokinetics, Inc. | Cardiac sarcomere inhibitors |
| WO2020257609A1 (en) * | 2019-06-21 | 2020-12-24 | MyoKardia, Inc. | Diagnostics and treatments for cardiac disease |
| CN110698415B (zh) * | 2019-10-21 | 2023-05-09 | 上海先行医药开发有限公司 | 一种肌球蛋白抑制剂及其制备方法和用途 |
| TW202134259A (zh) * | 2019-11-10 | 2021-09-16 | 美商邁奧卡迪亞公司 | 用肌凝蛋白調節劑之治療方法 |
| CA3165995A1 (en) * | 2020-01-28 | 2021-08-05 | Lorena KORDIC | Solid state forms of mavacamten and process for preparation thereof |
| CA3190060A1 (en) | 2020-08-28 | 2022-03-03 | MyoKardia, Inc. | Methods of treatment with myosin modulator |
| TW202227420A (zh) | 2020-11-20 | 2022-07-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 三嗪二酮類衍生物、其製備方法及其在醫藥上的應用 |
| US20240082248A1 (en) * | 2021-02-01 | 2024-03-14 | Dr. Reddy's Laboratories Limited | Process for preparation of mavacamten and solid state forms thereof |
| EP4301760A1 (en) | 2021-03-04 | 2024-01-10 | Cytokinetics, Inc. | Cardiac sarcomere inhibitors |
| CN112939876A (zh) * | 2021-03-10 | 2021-06-11 | 杭州科巢生物科技有限公司 | Mavacamten的晶型I及其制备方法 |
| WO2022189599A1 (en) | 2021-03-12 | 2022-09-15 | Sandoz Ag | Crystalline forms of mavacamten for the treatment of hcm |
| PL4370116T3 (pl) * | 2021-07-16 | 2025-04-28 | Cytokinetics, Inc. | Schematy dawkowania afikamtenu do leczenia obturacyjnej kardiomiopatii przerostowej |
| EP4404846B1 (en) * | 2021-09-24 | 2025-10-08 | Koninklijke Philips N.V. | Methods and systems for generating likelihood of heart failure with preserved ejection fraction (hfpef) |
| WO2024097284A1 (en) * | 2022-11-02 | 2024-05-10 | MyoKardia, Inc. | Mavacamten and derivatives thereof for use in treating atrial dysfunction |
| WO2024206339A1 (en) | 2023-03-27 | 2024-10-03 | Edgewise Therapeutics, Inc. | Quinolinone amide compounds and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202000071T1 (it) * | 2013-06-21 | 2020-03-13 | Myokardia Inc | Composti di pirimidinadione contro le condizioni cardiache |
-
2018
- 2018-08-03 JP JP2020505487A patent/JP2020529996A/ja active Pending
- 2018-08-03 SG SG10202112960QA patent/SG10202112960QA/en unknown
- 2018-08-03 WO PCT/US2018/045180 patent/WO2019028360A1/en not_active Ceased
- 2018-08-03 SM SM20250413T patent/SMT202500413T1/it unknown
- 2018-08-03 IL IL322175A patent/IL322175A/en unknown
- 2018-08-03 KR KR1020257024814A patent/KR20250116181A/ko active Pending
- 2018-08-03 KR KR1020207004507A patent/KR20200035973A/ko not_active Ceased
- 2018-08-03 IL IL272300A patent/IL272300B1/en unknown
- 2018-08-03 LT LTEPPCT/US2018/045180T patent/LT3661514T/lt unknown
- 2018-08-03 RU RU2020109345A patent/RU2020109345A/ru unknown
- 2018-08-03 SG SG11202000549TA patent/SG11202000549TA/en unknown
- 2018-08-03 EP EP18759209.2A patent/EP3661514B1/en active Active
- 2018-08-03 CN CN201880050881.4A patent/CN111182901A/zh active Pending
- 2018-08-03 MA MA049760A patent/MA49760A/fr unknown
- 2018-08-03 MY MYPI2020000493A patent/MY208231A/en unknown
- 2018-08-03 CA CA3071948A patent/CA3071948A1/en active Pending
- 2018-08-03 AU AU2018311974A patent/AU2018311974B2/en active Active
- 2018-08-03 MX MX2020001406A patent/MX2020001406A/es unknown
- 2018-08-03 EP EP25196218.9A patent/EP4659806A2/en active Pending
- 2018-08-03 CN CN202410743651.3A patent/CN118593507A/zh active Pending
- 2018-08-06 UY UY0001037834A patent/UY37834A/es not_active Application Discontinuation
-
2019
- 2019-03-26 US US16/364,322 patent/US20200054636A1/en not_active Abandoned
-
2020
- 2020-02-04 MX MX2024008096A patent/MX2024008096A/es unknown
- 2020-02-04 MX MX2024000348A patent/MX2024000348A/es unknown
-
2022
- 2022-03-23 US US17/701,863 patent/US20220226324A1/en not_active Abandoned
- 2022-06-16 US US17/842,389 patent/US20220313695A1/en not_active Abandoned
-
2023
- 2023-02-01 JP JP2023014110A patent/JP2023065372A/ja active Pending
-
2024
- 2024-06-07 AU AU2024203872A patent/AU2024203872A1/en active Pending
- 2024-09-06 US US18/827,049 patent/US20240423981A1/en not_active Abandoned
- 2024-11-01 JP JP2024192836A patent/JP2025020292A/ja active Pending
-
2025
- 2025-03-18 US US19/082,967 patent/US20250213565A1/en active Pending
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