JP2020529988A5 - - Google Patents
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- JP2020529988A5 JP2020529988A5 JP2020505233A JP2020505233A JP2020529988A5 JP 2020529988 A5 JP2020529988 A5 JP 2020529988A5 JP 2020505233 A JP2020505233 A JP 2020505233A JP 2020505233 A JP2020505233 A JP 2020505233A JP 2020529988 A5 JP2020529988 A5 JP 2020529988A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- substituted
- compound according
- group substituted
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762540860P | 2017-08-03 | 2017-08-03 | |
| US62/540,860 | 2017-08-03 | ||
| PCT/US2018/045175 WO2019028357A1 (en) | 2017-08-03 | 2018-08-03 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF MEDICAL DISORDERS AND USES THEREOF |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020529988A JP2020529988A (ja) | 2020-10-15 |
| JP2020529988A5 true JP2020529988A5 (enExample) | 2021-09-09 |
| JP7498108B2 JP7498108B2 (ja) | 2024-06-11 |
Family
ID=65233534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020505233A Active JP7498108B2 (ja) | 2017-08-03 | 2018-08-03 | 医学的障害の予防および治療のための化合物およびその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11583530B2 (enExample) |
| EP (1) | EP3661502A4 (enExample) |
| JP (1) | JP7498108B2 (enExample) |
| KR (1) | KR102692840B1 (enExample) |
| CN (1) | CN111032039B (enExample) |
| AU (1) | AU2018309085B2 (enExample) |
| BR (1) | BR112020001698A2 (enExample) |
| CA (1) | CA3069745A1 (enExample) |
| IL (1) | IL272097B2 (enExample) |
| MX (1) | MX2020001256A (enExample) |
| WO (1) | WO2019028357A1 (enExample) |
| ZA (1) | ZA202000375B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI744300B (zh) * | 2016-03-23 | 2021-11-01 | 里爾中央醫學中心 | 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途 |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| CN111032039B (zh) | 2017-08-03 | 2024-03-26 | 卡莱克汀科学有限责任公司 | 用于预防和治疗医学障碍的化合物及其用途 |
| KR20210124308A (ko) | 2019-01-30 | 2021-10-14 | 트루바인딩 아이엔씨. | 항-gal3 항체 및 이의 용도 |
| MX2022014786A (es) | 2020-05-26 | 2023-01-16 | Truebinding Inc | Metodos para tratar enfermedades inflamatorias mediante el bloqueo de galectina-3. |
| CN117897406A (zh) * | 2021-06-08 | 2024-04-16 | 真和制药有限公司 | 抗gal3抗体及其用于胰岛素抵抗的方法 |
| CN113476442A (zh) * | 2021-07-28 | 2021-10-08 | 上海交通大学医学院附属第九人民医院 | 化合物gb-0139在治疗心肌梗死后心肌过度纤维化的药物中的应用 |
| GB2631509A (en) * | 2023-07-04 | 2025-01-08 | Univ Liverpool | Compositions |
| GB2631507A (en) * | 2023-07-04 | 2025-01-08 | Univ Liverpool | Compositions |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT377586B (de) * | 1981-06-30 | 1985-04-10 | Erba Farmitalia | Verfahren zur herstellung von substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)chinazolinen |
| IL69274A (en) * | 1982-08-05 | 1986-08-31 | Erba Farmitalia | (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them |
| SE0100172D0 (sv) * | 2001-01-22 | 2001-01-22 | Ulf Nilsson | New inhibitors against galectins |
| EP1363638A4 (en) | 2001-01-31 | 2010-01-06 | Lundbeck & Co As H | USE OF GAL3 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF DEPRESSION AND / OR ANXIETIES AND USEFUL CONNECTIONS FOR SUCH PROCEDURES |
| US20030078271A1 (en) | 2001-01-31 | 2003-04-24 | Blackburn Thomas P. | Use of GAL3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods |
| JP4498922B2 (ja) * | 2002-07-09 | 2010-07-07 | アクテリオン ファーマシューティカルズ リミテッド | ７，８，９，１０−テトラヒドロ−６Ｈ−アゼピノ、６，７，８，９−テトラヒドロ−ピリドおよび２，３−ジヒドロ−２Ｈ−ピロロ［２，１−ｂ］−キナゾリノン誘導体 |
| US7220775B2 (en) | 2002-08-07 | 2007-05-22 | H. Lundbeck A/S | Compound useful for the treatment of neuropathic pain |
| DE10304141B4 (de) * | 2003-02-03 | 2006-03-09 | Hf Arzneimittelforschung Gmbh | Verfahren zur Herstellung von Chinazolin-Alkaloiden |
| WO2012158913A2 (en) * | 2011-05-17 | 2012-11-22 | Discoverybiomed Inc. | Treating protein folding disorders with small molecule cftr correctors |
| ES2562903T3 (es) * | 2011-07-13 | 2016-03-09 | Santen Pharmaceutical Co., Ltd | Nuevo compuesto que tiene actividad inhibidora de PARP |
| WO2016004093A2 (en) * | 2014-07-01 | 2016-01-07 | Stealth Biotherapeutics Corp | Therapeutic compositions including galectin-3 inhibitors and uses thereof |
| CA2970062C (en) | 2015-01-30 | 2023-02-28 | Galecto Biotech Ab | Alpha-d-galactoside inhibitors of galectins |
| CN105272986A (zh) * | 2015-06-15 | 2016-01-27 | 厦门医学高等专科学校 | 一种可抑制乙酰胆碱酯酶活性的化合物或其制备方法和应用 |
| CN106220631B (zh) * | 2016-07-26 | 2019-02-05 | 中山大学 | 一种7位氟取代Isaindigotone衍生物及其制备方法和在制备抗癌药物中的应用 |
| CN111032039B (zh) | 2017-08-03 | 2024-03-26 | 卡莱克汀科学有限责任公司 | 用于预防和治疗医学障碍的化合物及其用途 |
-
2018
- 2018-08-03 CN CN201880050555.3A patent/CN111032039B/zh active Active
- 2018-08-03 KR KR1020207005279A patent/KR102692840B1/ko active Active
- 2018-08-03 AU AU2018309085A patent/AU2018309085B2/en active Active
- 2018-08-03 EP EP18841404.9A patent/EP3661502A4/en active Pending
- 2018-08-03 BR BR112020001698-5A patent/BR112020001698A2/pt not_active Application Discontinuation
- 2018-08-03 US US16/629,373 patent/US11583530B2/en active Active
- 2018-08-03 WO PCT/US2018/045175 patent/WO2019028357A1/en not_active Ceased
- 2018-08-03 MX MX2020001256A patent/MX2020001256A/es unknown
- 2018-08-03 IL IL272097A patent/IL272097B2/en unknown
- 2018-08-03 CA CA3069745A patent/CA3069745A1/en active Pending
- 2018-08-03 JP JP2020505233A patent/JP7498108B2/ja active Active
-
2020
- 2020-01-20 ZA ZA2020/00375A patent/ZA202000375B/en unknown
-
2022
- 2022-07-08 US US17/861,023 patent/US12377102B2/en active Active
-
2025
- 2025-07-08 US US19/262,346 patent/US20260060985A1/en active Pending
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