JP2020527036A5 - - Google Patents
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- Publication number
- JP2020527036A5 JP2020527036A5 JP2019572845A JP2019572845A JP2020527036A5 JP 2020527036 A5 JP2020527036 A5 JP 2020527036A5 JP 2019572845 A JP2019572845 A JP 2019572845A JP 2019572845 A JP2019572845 A JP 2019572845A JP 2020527036 A5 JP2020527036 A5 JP 2020527036A5
- Authority
- JP
- Japan
- Prior art keywords
- cell receptor
- cell
- molecule
- seq
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108091008874 T cell receptors Proteins 0.000 claims 27
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 26
- 210000001744 T-lymphocyte Anatomy 0.000 claims 17
- 206010028980 Neoplasm Diseases 0.000 claims 16
- 210000004027 cell Anatomy 0.000 claims 12
- 239000000833 heterodimer Substances 0.000 claims 12
- 201000011510 cancer Diseases 0.000 claims 10
- 238000000034 method Methods 0.000 claims 10
- 150000007523 nucleic acids Chemical group 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 239000000427 antigen Substances 0.000 claims 7
- 108091007433 antigens Proteins 0.000 claims 7
- 102000036639 antigens Human genes 0.000 claims 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 6
- 238000002360 preparation method Methods 0.000 claims 6
- 102000006707 alpha-beta T-Cell Antigen Receptors Human genes 0.000 claims 4
- 102000011778 gamma-delta T-Cell Antigen Receptors Human genes 0.000 claims 4
- 108010062214 gamma-delta T-Cell Antigen Receptors Proteins 0.000 claims 3
- 108700019146 Transgenes Proteins 0.000 claims 2
- 108010087408 alpha-beta T-Cell Antigen Receptors Proteins 0.000 claims 2
- 238000002955 isolation Methods 0.000 claims 2
- 210000004881 tumor cell Anatomy 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 230000009258 tissue cross reactivity Effects 0.000 claims 1
- 210000003171 tumor-infiltrating lymphocyte Anatomy 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023020851A JP7515209B2 (ja) | 2017-03-07 | 2023-02-14 | 癌免疫療法用ｍｒ１制限ｔ細胞受容体 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17159754.5 | 2017-03-07 | ||
| EP17159754 | 2017-03-07 | ||
| EP17179309.4 | 2017-07-03 | ||
| EP17179309 | 2017-07-03 | ||
| PCT/EP2018/055620 WO2018162563A1 (en) | 2017-03-07 | 2018-03-07 | Mr1 restricted t cell receptors for cancer immunotherapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023020851A Division JP7515209B2 (ja) | 2017-03-07 | 2023-02-14 | 癌免疫療法用ｍｒ１制限ｔ細胞受容体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020527036A JP2020527036A (ja) | 2020-09-03 |
| JP2020527036A5 true JP2020527036A5 (enExample) | 2021-02-18 |
| JP7233103B2 JP7233103B2 (ja) | 2023-03-06 |
Family
ID=61563412
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019572845A Active JP7233103B2 (ja) | 2017-03-07 | 2018-03-07 | 癌免疫療法用ｍｒ１制限ｔ細胞受容体 |
| JP2023020851A Active JP7515209B2 (ja) | 2017-03-07 | 2023-02-14 | 癌免疫療法用ｍｒ１制限ｔ細胞受容体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023020851A Active JP7515209B2 (ja) | 2017-03-07 | 2023-02-14 | 癌免疫療法用ｍｒ１制限ｔ細胞受容体 |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP3592839B1 (enExample) |
| JP (2) | JP7233103B2 (enExample) |
| KR (1) | KR20190126332A (enExample) |
| CN (1) | CN110462024B (enExample) |
| AU (1) | AU2018231405B2 (enExample) |
| CA (1) | CA3054758A1 (enExample) |
| IL (1) | IL268813A (enExample) |
| WO (1) | WO2018162563A1 (enExample) |
| ZA (1) | ZA201905579B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3469361B1 (en) | 2016-06-10 | 2024-07-31 | Gadeta B.V. | Novel method for identifying deltat-cell (or gammat-cell) receptor chains or parts thereof that mediate an anti-tumour or an anti-infective response |
| CN110944658A (zh) | 2017-05-18 | 2020-03-31 | Umc乌德勒支控股有限公司 | 用于细胞靶向疗法的组合物和方法 |
| GB201717578D0 (en) * | 2017-10-26 | 2017-12-13 | Univ College Cardiff Consultants Ltd | Novel T-cell receptor |
| WO2019204683A1 (en) * | 2018-04-19 | 2019-10-24 | Board Of Regents, The University Of Texas System | T cell receptors with mage-b2 specificity and uses thereof |
| AU2019338226A1 (en) * | 2018-09-12 | 2021-02-11 | Universität Basel | MR1 restricted T cell receptors for cancer immunotherapy |
| US20210369776A1 (en) * | 2018-12-06 | 2021-12-02 | Guangdong Tcrcure Biopharma Technology Co., Ltd. | Combinational tcr-t cell therapy targeting tumor antigens, tgf-beta, and immune checkpoints |
| WO2022118043A1 (en) | 2020-12-03 | 2022-06-09 | Enara Bio Limited | Novel protein-ligand complex |
| WO2022248881A1 (en) | 2021-05-28 | 2022-12-01 | Enara Bio Limited | Novel protein-ligand complex |
| KR20230088292A (ko) * | 2021-12-10 | 2023-06-19 | 주식회사 유틸렉스 | MR1 제한적 Panck T 세포 및 이의 제조방법 |
| EP4472742A1 (en) * | 2022-02-03 | 2024-12-11 | University College Cardiff Consultants Limited | Novel t-cell receptor |
| CN119587561B (zh) * | 2024-12-09 | 2025-11-28 | 新乡医学院 | THP在制备增强Vγ9Vδ2 T细胞抗肿瘤疗效的药物中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL104684A0 (en) * | 1992-02-14 | 1993-06-10 | Bristol Myers Squibb Co | The cd40cr receptor and ligands therefor |
| US7829289B2 (en) * | 2002-05-14 | 2010-11-09 | Institut National De La Sante Et De Recherche Medicale | T cell subpopulation regulating gut immunity |
| JP6126804B2 (ja) * | 2012-07-25 | 2017-05-10 | 国立大学法人富山大学 | Ｔ細胞受容体のクローニング方法 |
| ES2746240T3 (es) * | 2013-03-13 | 2020-03-05 | Health Research Inc | Composiciones y procedimientos para la utilización de receptores de células T recombinantes para el reconocimiento directo de un antígeno tumoral |
| WO2015149130A1 (en) * | 2014-04-01 | 2015-10-08 | The University Of Queensland | Immunological reagents and uses therefor |
-
2018
- 2018-03-07 CA CA3054758A patent/CA3054758A1/en active Pending
- 2018-03-07 JP JP2019572845A patent/JP7233103B2/ja active Active
- 2018-03-07 WO PCT/EP2018/055620 patent/WO2018162563A1/en not_active Ceased
- 2018-03-07 EP EP18708695.4A patent/EP3592839B1/en active Active
- 2018-03-07 CN CN201880016990.4A patent/CN110462024B/zh active Active
- 2018-03-07 KR KR1020197027180A patent/KR20190126332A/ko active Pending
- 2018-03-07 EP EP23181086.2A patent/EP4273233A3/en not_active Withdrawn
- 2018-03-07 AU AU2018231405A patent/AU2018231405B2/en active Active
-
2019
- 2019-08-21 IL IL26881319A patent/IL268813A/en unknown
- 2019-08-23 ZA ZA2019/05579A patent/ZA201905579B/en unknown
-
2023
- 2023-02-14 JP JP2023020851A patent/JP7515209B2/ja active Active
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