JP2020525416A - 眼表面障害の治療及び診断 - Google Patents
眼表面障害の治療及び診断 Download PDFInfo
- Publication number
- JP2020525416A JP2020525416A JP2019569289A JP2019569289A JP2020525416A JP 2020525416 A JP2020525416 A JP 2020525416A JP 2019569289 A JP2019569289 A JP 2019569289A JP 2019569289 A JP2019569289 A JP 2019569289A JP 2020525416 A JP2020525416 A JP 2020525416A
- Authority
- JP
- Japan
- Prior art keywords
- heparin
- ophthalmic formulation
- ophthalmic
- ocular surface
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2006—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762526891P | 2017-06-29 | 2017-06-29 | |
| US62/526,891 | 2017-06-29 | ||
| US201762575508P | 2017-10-22 | 2017-10-22 | |
| US62/575,508 | 2017-10-22 | ||
| PCT/US2018/020455 WO2019005222A1 (en) | 2017-06-29 | 2018-03-01 | TREATMENT AND DIAGNOSIS OF OCULAR SURFACE DISORDERS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020525416A true JP2020525416A (ja) | 2020-08-27 |
| JP2020525416A5 JP2020525416A5 (enExample) | 2021-05-20 |
Family
ID=64734716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019569289A Pending JP2020525416A (ja) | 2017-06-29 | 2018-03-01 | 眼表面障害の治療及び診断 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US11058713B2 (enExample) |
| EP (1) | EP3644966A4 (enExample) |
| JP (1) | JP2020525416A (enExample) |
| WO (1) | WO2019005222A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024042858A1 (ja) * | 2022-08-23 | 2024-02-29 | 株式会社エムズサイエンス | 角膜障害治療剤 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230091716A1 (en) * | 2020-02-12 | 2023-03-23 | Glia, Llc | Progesterone Combinations |
| DE102020104540A1 (de) * | 2020-02-20 | 2021-08-26 | Carl Zeiss Meditec Ag | Ophthalmologische Zusammensetzung und Detektionsvorrichtung für ein medizinisches Gerät |
| CA3199736A1 (en) | 2020-11-23 | 2022-05-27 | Sight Sciences, Inc. | Formulations and methods for treating conditions of the eye |
| KR102391198B1 (ko) * | 2021-08-27 | 2022-04-27 | 한림제약(주) | 리피테그라스트 또는 이의 약제학적으로 허용가능한 염을 포함하는 수용액 형태의 점안액 조성물 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10161149A1 (de) * | 2001-12-12 | 2003-06-26 | Ursapharm Arzneimittel Gmbh | Heparin-haltiges Ophthalmikum |
| CN1459291A (zh) * | 2003-05-28 | 2003-12-03 | 凌沛学 | 含低分子肝素的滴眼液及其制备方法 |
| JP2007523912A (ja) * | 2004-02-26 | 2007-08-23 | アドバンスト アキュラー システムズ リミテッド | 眼病変治療用へパリン |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2618074A1 (fr) * | 1987-07-15 | 1989-01-20 | Siepser Steven | Formulation destinee a etre utilisee en chirurgie de l'oeil |
| US6231889B1 (en) * | 1998-09-21 | 2001-05-15 | Chronorx, Llc | Unit dosage forms for the treatment of herpes simplex |
| AU6870800A (en) * | 1999-09-06 | 2001-04-10 | Ono Pharmaceutical Co. Ltd. | Preventive and therapeutic agents for eye diseases |
| CN1394610A (zh) * | 2002-07-12 | 2003-02-05 | 黄建林 | 肝素钙眼药水 |
| GB0404693D0 (en) * | 2004-03-02 | 2004-04-07 | Univ London | Pharmaceutical preparations for the treatment of ocular surface and other disorders |
| US8372814B2 (en) * | 2004-06-07 | 2013-02-12 | Ista Pharmaceuticals, Inc. | Ophthalmic formulations and uses thereof |
| US20060122152A1 (en) * | 2004-12-03 | 2006-06-08 | Peyman Gholam A | Heparin for the treatment of ocular pathologies |
| US20060276440A1 (en) * | 2005-01-03 | 2006-12-07 | An Wenqian F | Treatment of inflammatory disorders |
| WO2006086638A2 (en) * | 2005-02-10 | 2006-08-17 | Board Of Regents, The University Of Texas System | Targeting lipocalin-2 for cancer therapeutics |
| US20100189721A1 (en) * | 2007-07-06 | 2010-07-29 | Smithkline Beecham Corporation | Antibody formulations |
| US20090253661A1 (en) * | 2008-04-04 | 2009-10-08 | Gholam A. Peyman | Ocular agents |
| ES2713519T3 (es) * | 2011-12-12 | 2019-05-22 | Univ Illinois | Composición y método para el tratamiento de una enfermedad ocular relacionada con los ácidos nucleicos |
| BR112014015430B1 (pt) * | 2011-12-23 | 2022-03-03 | Western Sydney University | Compostos, formulações oftálmicas e seus usos |
| RU2535115C1 (ru) * | 2013-05-15 | 2014-12-10 | Бости Трейдинг Лтд | Фармацевтический состав, содержащий нейротоксин ботулина |
| CN106170498A (zh) * | 2014-01-14 | 2016-11-30 | 科马布有限公司 | 抗‑light抗体 |
| WO2016201202A1 (en) * | 2015-06-11 | 2016-12-15 | Attwill Medical Solutions Inc. | Medical devices, systems, and methods utilizing antithrombin-heparin compositions |
| WO2017148951A1 (en) * | 2016-02-29 | 2017-09-08 | Santen Sas | Gene signature for the prognosis of dry eye disease |
-
2018
- 2018-03-01 WO PCT/US2018/020455 patent/WO2019005222A1/en not_active Ceased
- 2018-03-01 US US15/909,239 patent/US11058713B2/en active Active
- 2018-03-01 EP EP18824265.5A patent/EP3644966A4/en not_active Withdrawn
- 2018-03-01 JP JP2019569289A patent/JP2020525416A/ja active Pending
-
2021
- 2021-06-28 US US17/361,310 patent/US20210322457A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10161149A1 (de) * | 2001-12-12 | 2003-06-26 | Ursapharm Arzneimittel Gmbh | Heparin-haltiges Ophthalmikum |
| JP2005513106A (ja) * | 2001-12-12 | 2005-05-12 | ウーアザファルマ アールツナイミッテル ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント カンパニー カーゲー | ヘパリンを保有する眼薬剤 |
| CN1459291A (zh) * | 2003-05-28 | 2003-12-03 | 凌沛学 | 含低分子肝素的滴眼液及其制备方法 |
| JP2007523912A (ja) * | 2004-02-26 | 2007-08-23 | アドバンスト アキュラー システムズ リミテッド | 眼病変治療用へパリン |
Non-Patent Citations (2)
| Title |
|---|
| J KOREAN OPHTHALMOL SOC, vol. 51, no. 8, JPN6023013118, 2010, pages 1047 - 1053, ISSN: 0005024786 * |
| 第十六改正日本薬局方, JPN6022010818, 2011, pages 1042 - 1044, ISSN: 0005024785 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024042858A1 (ja) * | 2022-08-23 | 2024-02-29 | 株式会社エムズサイエンス | 角膜障害治療剤 |
| JP2024030200A (ja) * | 2022-08-23 | 2024-03-07 | 株式会社エムズサイエンス | 角膜障害治療剤 |
| JP7514033B2 (ja) | 2022-08-23 | 2024-07-10 | 株式会社エムズサイエンス | 角膜障害治療剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20210322457A1 (en) | 2021-10-21 |
| WO2019005222A1 (en) | 2019-01-03 |
| US20190000871A1 (en) | 2019-01-03 |
| EP3644966A4 (en) | 2021-03-24 |
| EP3644966A1 (en) | 2020-05-06 |
| US11058713B2 (en) | 2021-07-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20210322457A1 (en) | Treatment and diagnosis of ocular surface disorders | |
| US9877645B2 (en) | Inflammatory eye disorders | |
| JP7624220B2 (ja) | 自己抗体媒介性眼疾患の治療および診断 | |
| López-Plandolit et al. | Efficacy of plasma rich in growth factors for the treatment of dry eye | |
| Schechter et al. | Efficacy of topical cyclosporine for the treatment of ocular rosacea | |
| CN113164043B (zh) | 用于青光眼的组合物和方法 | |
| Al-Saedi et al. | Dry eye disease: present challenges in the management and future trends | |
| JP2024116245A (ja) | 乾性眼疾患の治療のための眼科用組成物 | |
| CN115943314A (zh) | 干眼病生物标志物及其治疗用途 | |
| CN1964719B (zh) | 依碳酸氯替泼诺用于制备治疗干眼症的药物的用途 | |
| KR20170048426A (ko) | 시각 장애를 치료하기 위한 조성물 및 방법 | |
| Monk et al. | Detection of endogenous cortisol in equine tears and blood at rest and after simulated stress | |
| WO2022150580A1 (en) | Treatment of dry eye disease | |
| US20200054745A1 (en) | Methods for treatment of age-related macular degeneration | |
| JP6544806B2 (ja) | 眼疾患の治療および診断 | |
| Tomida et al. | Correlations between tear fluid and aqueous humor cytokine levels in bullous keratopathy | |
| Heiligenhaus et al. | Everolimus for the treatment of uveitis refractory to cyclosporine A: a pilot study | |
| US20150307619A1 (en) | Use of C-C Chemokine Receptor Type 7 (CCR7) Inhibitors | |
| RU2845362C2 (ru) | Лечение и диагностика опосредованных аутоантителами глазных заболеваний | |
| JPWO2020097528A5 (enExample) | ||
| Kai et al. | Evaluation methods using tear volume in a conjunctivitis mice model | |
| Mirghani et al. | Updates on Diagnosis, Clinical Presentation, and Management of Ocular Cicatricial Pemphigoid (OCP): A Systematic Review | |
| Muna et al. | Ocular cicatricial pemphigoid | |
| Eguiluz-Gracia et al. | Local mucosal allergic disease | |
| Amorim | Tears biomarkers for diagnosis strategy of diabetic retinopathy onset |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20210226 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20210407 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20220322 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220621 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20220815 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20221215 |
|
| C60 | Trial request (containing other claim documents, opposition documents) |
Free format text: JAPANESE INTERMEDIATE CODE: C60 Effective date: 20221215 |
|
| C11 | Written invitation by the commissioner to file amendments |
Free format text: JAPANESE INTERMEDIATE CODE: C11 Effective date: 20230110 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20230131 |
|
| C21 | Notice of transfer of a case for reconsideration by examiners before appeal proceedings |
Free format text: JAPANESE INTERMEDIATE CODE: C21 Effective date: 20230201 |
|
| A912 | Re-examination (zenchi) completed and case transferred to appeal board |
Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20230331 |
|
| C211 | Notice of termination of reconsideration by examiners before appeal proceedings |
Free format text: JAPANESE INTERMEDIATE CODE: C211 Effective date: 20230404 |