JP2020523983A5 - - Google Patents
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- Publication number
- JP2020523983A5 JP2020523983A5 JP2019561875A JP2019561875A JP2020523983A5 JP 2020523983 A5 JP2020523983 A5 JP 2020523983A5 JP 2019561875 A JP2019561875 A JP 2019561875A JP 2019561875 A JP2019561875 A JP 2019561875A JP 2020523983 A5 JP2020523983 A5 JP 2020523983A5
- Authority
- JP
- Japan
- Prior art keywords
- host cell
- nucleic acid
- arc
- arc capsid
- capsid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023076834A JP7774319B2 (ja) | 2017-05-10 | 2023-05-08 | Ａｒｃカプシドの組成物及び使用方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762504370P | 2017-05-10 | 2017-05-10 | |
| US62/504,370 | 2017-05-10 | ||
| US201762543130P | 2017-08-09 | 2017-08-09 | |
| US62/543,130 | 2017-08-09 | ||
| PCT/US2018/032105 WO2018209113A1 (en) | 2017-05-10 | 2018-05-10 | Compositions and methods of use of arc capsids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023076834A Division JP7774319B2 (ja) | 2017-05-10 | 2023-05-08 | Ａｒｃカプシドの組成物及び使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020523983A JP2020523983A (ja) | 2020-08-13 |
| JP2020523983A5 true JP2020523983A5 (enExample) | 2021-07-26 |
| JP7355382B2 JP7355382B2 (ja) | 2023-10-03 |
Family
ID=64104936
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019561875A Active JP7355382B2 (ja) | 2017-05-10 | 2018-05-10 | Ａｒｃカプシドの組成物及び使用方法 |
| JP2023076834A Active JP7774319B2 (ja) | 2017-05-10 | 2023-05-08 | Ａｒｃカプシドの組成物及び使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023076834A Active JP7774319B2 (ja) | 2017-05-10 | 2023-05-08 | Ａｒｃカプシドの組成物及び使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210189432A1 (enExample) |
| EP (1) | EP3621660A4 (enExample) |
| JP (2) | JP7355382B2 (enExample) |
| CN (1) | CN110997011A (enExample) |
| AU (1) | AU2018265395B2 (enExample) |
| CA (1) | CA3062614A1 (enExample) |
| WO (1) | WO2018209113A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US20210163933A1 (en) * | 2017-12-11 | 2021-06-03 | University Of Massachusetts | Arc protein extracellular vesicle nucleic acid delivery platform |
| EP3820495A4 (en) | 2018-07-09 | 2022-07-20 | The Broad Institute Inc. | RNA-PROGRAMMABLE EPIGENETIC RNA MODIFIERS AND THEIR USES |
| EP3852813A4 (en) | 2018-09-18 | 2022-06-22 | VNV Newco Inc. | ARC-BASED CAPSIDS AND THEIR USES |
| US20210403907A1 (en) | 2018-09-18 | 2021-12-30 | Vnv Newco Inc. | Arc-based capsids and uses thereof |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| WO2020191241A1 (en) | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
| WO2020214842A1 (en) | 2019-04-17 | 2020-10-22 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| US20220259617A1 (en) | 2019-06-13 | 2022-08-18 | The General Hospital Corporation | Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells |
| US11129892B1 (en) | 2020-05-18 | 2021-09-28 | Vnv Newco Inc. | Vaccine compositions comprising endogenous Gag polypeptides |
| BR112023001272A2 (pt) | 2020-07-24 | 2023-04-04 | Massachusetts Gen Hospital | Partículas semelhantes a vírus aprimoradas e métodos de uso das mesmas para entrega às células |
| WO2022235723A1 (en) * | 2021-05-04 | 2022-11-10 | Cornell University | Engineered extracellular vesicles |
| EP4565594A2 (en) * | 2022-08-01 | 2025-06-11 | University of Utah Research Foundation | Compositions and methods for labeling and detecting binding partners |
| CN118576725B (zh) * | 2024-08-02 | 2025-06-03 | 中国人民解放军军事科学院军事医学研究院 | 一种以arc蛋白为载体的纳米颗粒及其制备方法和应用 |
| CN120248078B (zh) * | 2025-05-28 | 2025-11-28 | 中国人民解放军军事科学院军事医学研究院 | 一种基于arc蛋白的修饰多肽及其作为核酸递送载体的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204059B1 (en) * | 1994-06-30 | 2001-03-20 | University Of Pittsburgh | AAV capsid vehicles for molecular transfer |
| US7638269B2 (en) * | 1997-02-07 | 2009-12-29 | The Regents Of The University Of California | Viral capsid assembly intermediates and methods of production |
| WO2009042727A1 (en) | 2007-09-24 | 2009-04-02 | The Johns Hopkins University | Immediate early gene arc interacts with endocytic machinery and regulates the trafficking and function of presenilin |
| WO2009097691A1 (en) * | 2008-02-08 | 2009-08-13 | University Health Network | USE OF P27kip1 FOR THE PREVENTION AND TREATMENT OF HEART FAILURE |
| HUE039908T2 (hu) * | 2009-02-02 | 2019-02-28 | Glaxosmithkline Biologicals Sa | Majom adenovírusból származó nukleinsav- és aminosav-szekvenciák, azt tartalmazó vektorok és alkalmazásuk |
| GB0911870D0 (en) * | 2009-07-08 | 2009-08-19 | Ucl Business Plc | Optimised coding sequence and promoter |
| EP2638060A2 (en) * | 2010-11-10 | 2013-09-18 | Laboratorios Del Dr. Esteve, S.A. | Highly immunogenic hiv p24 sequences |
| US11136557B2 (en) | 2013-05-31 | 2021-10-05 | The Regents Of The University Of California | Adeno-associated virus variants and methods of use thereof |
| US10624849B2 (en) | 2015-09-28 | 2020-04-21 | Northwestern University | Targeted extracellular vesicles comprising membrane proteins with engineered glycosylation sites |
-
2018
- 2018-05-10 CA CA3062614A patent/CA3062614A1/en active Pending
- 2018-05-10 EP EP18797884.6A patent/EP3621660A4/en active Pending
- 2018-05-10 AU AU2018265395A patent/AU2018265395B2/en active Active
- 2018-05-10 CN CN201880037751.7A patent/CN110997011A/zh active Pending
- 2018-05-10 US US16/610,408 patent/US20210189432A1/en active Pending
- 2018-05-10 WO PCT/US2018/032105 patent/WO2018209113A1/en not_active Ceased
- 2018-05-10 JP JP2019561875A patent/JP7355382B2/ja active Active
-
2023
- 2023-05-08 JP JP2023076834A patent/JP7774319B2/ja active Active
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