JP2020523983A5 - - Google Patents

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Publication number
JP2020523983A5
JP2020523983A5 JP2019561875A JP2019561875A JP2020523983A5 JP 2020523983 A5 JP2020523983 A5 JP 2020523983A5 JP 2019561875 A JP2019561875 A JP 2019561875A JP 2019561875 A JP2019561875 A JP 2019561875A JP 2020523983 A5 JP2020523983 A5 JP 2020523983A5
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JP
Japan
Prior art keywords
host cell
nucleic acid
arc
arc capsid
capsid
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JP2019561875A
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English (en)
Japanese (ja)
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JP7355382B2 (ja
JP2020523983A (ja
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Priority claimed from PCT/US2018/032105 external-priority patent/WO2018209113A1/en
Publication of JP2020523983A publication Critical patent/JP2020523983A/ja
Publication of JP2020523983A5 publication Critical patent/JP2020523983A5/ja
Priority to JP2023076834A priority Critical patent/JP7774319B2/ja
Application granted granted Critical
Publication of JP7355382B2 publication Critical patent/JP7355382B2/ja
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JP2019561875A 2017-05-10 2018-05-10 Ａｒｃカプシドの組成物及び使用方法 Active JP7355382B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023076834A JP7774319B2 (ja) 2017-05-10 2023-05-08 Ａｒｃカプシドの組成物及び使用方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762504370P 2017-05-10 2017-05-10
US62/504,370 2017-05-10
US201762543130P 2017-08-09 2017-08-09
US62/543,130 2017-08-09
PCT/US2018/032105 WO2018209113A1 (en) 2017-05-10 2018-05-10 Compositions and methods of use of arc capsids

Related Child Applications (1)

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JP2023076834A Division JP7774319B2 (ja) 2017-05-10 2023-05-08 Ａｒｃカプシドの組成物及び使用方法

Publications (3)

Publication Number Publication Date
JP2020523983A JP2020523983A (ja) 2020-08-13
JP2020523983A5 true JP2020523983A5 (enExample) 2021-07-26
JP7355382B2 JP7355382B2 (ja) 2023-10-03

Family

ID=64104936

Family Applications (2)

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JP2019561875A Active JP7355382B2 (ja) 2017-05-10 2018-05-10 Ａｒｃカプシドの組成物及び使用方法
JP2023076834A Active JP7774319B2 (ja) 2017-05-10 2023-05-08 Ａｒｃカプシドの組成物及び使用方法

Family Applications After (1)

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JP2023076834A Active JP7774319B2 (ja) 2017-05-10 2023-05-08 Ａｒｃカプシドの組成物及び使用方法

Country Status (7)

Country Link
US (1) US20210189432A1 (enExample)
EP (1) EP3621660A4 (enExample)
JP (2) JP7355382B2 (enExample)
CN (1) CN110997011A (enExample)
AU (1) AU2018265395B2 (enExample)
CA (1) CA3062614A1 (enExample)
WO (1) WO2018209113A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9340799B2 (en) 2013-09-06 2016-05-17 President And Fellows Of Harvard College MRNA-sensing switchable gRNAs
WO2019118497A1 (en) * 2017-12-11 2019-06-20 University Of Massachusetts Arc protein extracellular vesicle nucleic acid delivery platform
JP7344300B2 (ja) 2018-09-18 2023-09-13 ブイエヌブイ ニューコ インク． Ａｒｃベースのカプシドおよびその使用
US12351837B2 (en) 2019-01-23 2025-07-08 The Broad Institute, Inc. Supernegatively charged proteins and uses thereof
US12473543B2 (en) 2019-04-17 2025-11-18 The Broad Institute, Inc. Adenine base editors with reduced off-target effects
CN114258398A (zh) 2019-06-13 2022-03-29 总医院公司 工程化的人内源性病毒样颗粒及使用其递送至细胞的方法
US11129892B1 (en) 2020-05-18 2021-09-28 Vnv Newco Inc. Vaccine compositions comprising endogenous Gag polypeptides
BR112023001272A2 (pt) 2020-07-24 2023-04-04 Massachusetts Gen Hospital Partículas semelhantes a vírus aprimoradas e métodos de uso das mesmas para entrega às células
CN117580949A (zh) * 2021-05-04 2024-02-20 康奈尔大学 工程化的胞外囊泡
WO2024030455A2 (en) * 2022-08-01 2024-02-08 University Of Utah Research Foundation Compositions and methods for labeling and detecting binding partners
CN118576725B (zh) * 2024-08-02 2025-06-03 中国人民解放军军事科学院军事医学研究院 一种以arc蛋白为载体的纳米颗粒及其制备方法和应用
CN120248078B (zh) * 2025-05-28 2025-11-28 中国人民解放军军事科学院军事医学研究院 一种基于arc蛋白的修饰多肽及其作为核酸递送载体的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204059B1 (en) * 1994-06-30 2001-03-20 University Of Pittsburgh AAV capsid vehicles for molecular transfer
US7638269B2 (en) * 1997-02-07 2009-12-29 The Regents Of The University Of California Viral capsid assembly intermediates and methods of production
WO2009042727A1 (en) * 2007-09-24 2009-04-02 The Johns Hopkins University Immediate early gene arc interacts with endocytic machinery and regulates the trafficking and function of presenilin
WO2009097691A1 (en) * 2008-02-08 2009-08-13 University Health Network USE OF P27kip1 FOR THE PREVENTION AND TREATMENT OF HEART FAILURE
MX2011007980A (es) * 2009-02-02 2011-08-17 Okairos Ag Secuencias de acido nucleico y aminoacido de adenovirus de simio, vectores que contienen los mismos y usos de las mismas.
GB0911870D0 (en) * 2009-07-08 2009-08-19 Ucl Business Plc Optimised coding sequence and promoter
US20130302364A1 (en) * 2010-11-10 2013-11-14 Laboratorios Del Dr. Esteve, S.A. Highly immunogenic hiv p24 sequences
ES2897508T3 (es) * 2013-05-31 2022-03-01 Univ California Variantes de virus adenoasociados y métodos de uso de las mismas
US10624849B2 (en) * 2015-09-28 2020-04-21 Northwestern University Targeted extracellular vesicles comprising membrane proteins with engineered glycosylation sites

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