CA3062614A1 - Compositions and methods of use of arc capsids - Google Patents
Compositions and methods of use of arc capsids Download PDFInfo
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- CA3062614A1 CA3062614A1 CA3062614A CA3062614A CA3062614A1 CA 3062614 A1 CA3062614 A1 CA 3062614A1 CA 3062614 A CA3062614 A CA 3062614A CA 3062614 A CA3062614 A CA 3062614A CA 3062614 A1 CA3062614 A1 CA 3062614A1
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- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10023—Virus like particles [VLP]
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US201762504370P | 2017-05-10 | 2017-05-10 | |
| US62/504,370 | 2017-05-10 | ||
| US201762543130P | 2017-08-09 | 2017-08-09 | |
| US62/543,130 | 2017-08-09 | ||
| PCT/US2018/032105 WO2018209113A1 (en) | 2017-05-10 | 2018-05-10 | Compositions and methods of use of arc capsids |
Publications (1)
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| CA3062614A1 true CA3062614A1 (en) | 2018-11-15 |
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| CA3062614A Pending CA3062614A1 (en) | 2017-05-10 | 2018-05-10 | Compositions and methods of use of arc capsids |
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| US (1) | US20210189432A1 (enExample) |
| EP (1) | EP3621660A4 (enExample) |
| JP (2) | JP7355382B2 (enExample) |
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| AU (1) | AU2018265395B2 (enExample) |
| CA (1) | CA3062614A1 (enExample) |
| WO (1) | WO2018209113A1 (enExample) |
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| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| WO2019118497A1 (en) * | 2017-12-11 | 2019-06-20 | University Of Massachusetts | Arc protein extracellular vesicle nucleic acid delivery platform |
| JP7344300B2 (ja) | 2018-09-18 | 2023-09-13 | ブイエヌブイ ニューコ インク． | Ａｒｃベースのカプシドおよびその使用 |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| US12473543B2 (en) | 2019-04-17 | 2025-11-18 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| CN114258398A (zh) | 2019-06-13 | 2022-03-29 | 总医院公司 | 工程化的人内源性病毒样颗粒及使用其递送至细胞的方法 |
| US11129892B1 (en) | 2020-05-18 | 2021-09-28 | Vnv Newco Inc. | Vaccine compositions comprising endogenous Gag polypeptides |
| BR112023001272A2 (pt) | 2020-07-24 | 2023-04-04 | Massachusetts Gen Hospital | Partículas semelhantes a vírus aprimoradas e métodos de uso das mesmas para entrega às células |
| CN117580949A (zh) * | 2021-05-04 | 2024-02-20 | 康奈尔大学 | 工程化的胞外囊泡 |
| WO2024030455A2 (en) * | 2022-08-01 | 2024-02-08 | University Of Utah Research Foundation | Compositions and methods for labeling and detecting binding partners |
| CN118576725B (zh) * | 2024-08-02 | 2025-06-03 | 中国人民解放军军事科学院军事医学研究院 | 一种以arc蛋白为载体的纳米颗粒及其制备方法和应用 |
| CN120248078B (zh) * | 2025-05-28 | 2025-11-28 | 中国人民解放军军事科学院军事医学研究院 | 一种基于arc蛋白的修饰多肽及其作为核酸递送载体的应用 |
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| US6204059B1 (en) * | 1994-06-30 | 2001-03-20 | University Of Pittsburgh | AAV capsid vehicles for molecular transfer |
| US7638269B2 (en) * | 1997-02-07 | 2009-12-29 | The Regents Of The University Of California | Viral capsid assembly intermediates and methods of production |
| WO2009042727A1 (en) * | 2007-09-24 | 2009-04-02 | The Johns Hopkins University | Immediate early gene arc interacts with endocytic machinery and regulates the trafficking and function of presenilin |
| WO2009097691A1 (en) * | 2008-02-08 | 2009-08-13 | University Health Network | USE OF P27kip1 FOR THE PREVENTION AND TREATMENT OF HEART FAILURE |
| MX2011007980A (es) * | 2009-02-02 | 2011-08-17 | Okairos Ag | Secuencias de acido nucleico y aminoacido de adenovirus de simio, vectores que contienen los mismos y usos de las mismas. |
| GB0911870D0 (en) * | 2009-07-08 | 2009-08-19 | Ucl Business Plc | Optimised coding sequence and promoter |
| US20130302364A1 (en) * | 2010-11-10 | 2013-11-14 | Laboratorios Del Dr. Esteve, S.A. | Highly immunogenic hiv p24 sequences |
| ES2897508T3 (es) * | 2013-05-31 | 2022-03-01 | Univ California | Variantes de virus adenoasociados y métodos de uso de las mismas |
| US10624849B2 (en) * | 2015-09-28 | 2020-04-21 | Northwestern University | Targeted extracellular vesicles comprising membrane proteins with engineered glycosylation sites |
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- 2018-05-10 US US16/610,408 patent/US20210189432A1/en active Pending
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- 2018-05-10 EP EP18797884.6A patent/EP3621660A4/en active Pending
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2023
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| US20210189432A1 (en) | 2021-06-24 |
| AU2018265395A1 (en) | 2019-12-05 |
| EP3621660A4 (en) | 2021-01-20 |
| WO2018209113A1 (en) | 2018-11-15 |
| CN110997011A (zh) | 2020-04-10 |
| JP7355382B2 (ja) | 2023-10-03 |
| JP2023106451A (ja) | 2023-08-01 |
| JP7774319B2 (ja) | 2025-11-21 |
| EP3621660A1 (en) | 2020-03-18 |
| JP2020523983A (ja) | 2020-08-13 |
| AU2018265395B2 (en) | 2025-04-10 |
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