CN110997011A - Arc衣壳的组合物和使用方法 - Google Patents
Arc衣壳的组合物和使用方法 Download PDFInfo
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- CN110997011A CN110997011A CN201880037751.7A CN201880037751A CN110997011A CN 110997011 A CN110997011 A CN 110997011A CN 201880037751 A CN201880037751 A CN 201880037751A CN 110997011 A CN110997011 A CN 110997011A
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN118576725A (zh) * | 2024-08-02 | 2024-09-03 | 中国人民解放军军事科学院军事医学研究院 | 一种以arc蛋白为载体的纳米颗粒及其制备方法和应用 |
| CN120248078A (zh) * | 2025-05-28 | 2025-07-04 | 中国人民解放军军事科学院军事医学研究院 | 一种基于arc蛋白的修饰多肽及其作为核酸递送载体的应用 |
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| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| WO2019118497A1 (en) * | 2017-12-11 | 2019-06-20 | University Of Massachusetts | Arc protein extracellular vesicle nucleic acid delivery platform |
| JP7344300B2 (ja) | 2018-09-18 | 2023-09-13 | ブイエヌブイ ニューコ インク． | Ａｒｃベースのカプシドおよびその使用 |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| US12473543B2 (en) | 2019-04-17 | 2025-11-18 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| CN114258398A (zh) | 2019-06-13 | 2022-03-29 | 总医院公司 | 工程化的人内源性病毒样颗粒及使用其递送至细胞的方法 |
| US11129892B1 (en) | 2020-05-18 | 2021-09-28 | Vnv Newco Inc. | Vaccine compositions comprising endogenous Gag polypeptides |
| BR112023001272A2 (pt) | 2020-07-24 | 2023-04-04 | Massachusetts Gen Hospital | Partículas semelhantes a vírus aprimoradas e métodos de uso das mesmas para entrega às células |
| CN117580949A (zh) * | 2021-05-04 | 2024-02-20 | 康奈尔大学 | 工程化的胞外囊泡 |
| WO2024030455A2 (en) * | 2022-08-01 | 2024-02-08 | University Of Utah Research Foundation | Compositions and methods for labeling and detecting binding partners |
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| CN1612942A (zh) * | 2002-01-02 | 2005-05-04 | 加州大学评议会 | 病毒衣壳组装中间产物 |
| WO2009097691A1 (en) * | 2008-02-08 | 2009-08-13 | University Health Network | USE OF P27kip1 FOR THE PREVENTION AND TREATMENT OF HEART FAILURE |
| CA3003790A1 (en) * | 2009-07-08 | 2011-01-13 | St. Jude Children's Research Hospital | Codon-optimized factor viii variants |
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| US6204059B1 (en) * | 1994-06-30 | 2001-03-20 | University Of Pittsburgh | AAV capsid vehicles for molecular transfer |
| WO2009042727A1 (en) * | 2007-09-24 | 2009-04-02 | The Johns Hopkins University | Immediate early gene arc interacts with endocytic machinery and regulates the trafficking and function of presenilin |
| ES2897508T3 (es) * | 2013-05-31 | 2022-03-01 | Univ California | Variantes de virus adenoasociados y métodos de uso de las mismas |
| US10624849B2 (en) * | 2015-09-28 | 2020-04-21 | Northwestern University | Targeted extracellular vesicles comprising membrane proteins with engineered glycosylation sites |
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| WO2009097691A1 (en) * | 2008-02-08 | 2009-08-13 | University Health Network | USE OF P27kip1 FOR THE PREVENTION AND TREATMENT OF HEART FAILURE |
| CN102300872A (zh) * | 2009-02-02 | 2011-12-28 | 奥凯罗斯股份公司 | 猿腺病毒核酸和氨基酸序列，包含其的载体及其用途 |
| CA3003790A1 (en) * | 2009-07-08 | 2011-01-13 | St. Jude Children's Research Hospital | Codon-optimized factor viii variants |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118576725A (zh) * | 2024-08-02 | 2024-09-03 | 中国人民解放军军事科学院军事医学研究院 | 一种以arc蛋白为载体的纳米颗粒及其制备方法和应用 |
| CN118576725B (zh) * | 2024-08-02 | 2025-06-03 | 中国人民解放军军事科学院军事医学研究院 | 一种以arc蛋白为载体的纳米颗粒及其制备方法和应用 |
| CN120248078A (zh) * | 2025-05-28 | 2025-07-04 | 中国人民解放军军事科学院军事医学研究院 | 一种基于arc蛋白的修饰多肽及其作为核酸递送载体的应用 |
| CN120248078B (zh) * | 2025-05-28 | 2025-11-28 | 中国人民解放军军事科学院军事医学研究院 | 一种基于arc蛋白的修饰多肽及其作为核酸递送载体的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20210189432A1 (en) | 2021-06-24 |
| AU2018265395A1 (en) | 2019-12-05 |
| EP3621660A4 (en) | 2021-01-20 |
| WO2018209113A1 (en) | 2018-11-15 |
| JP7355382B2 (ja) | 2023-10-03 |
| CA3062614A1 (en) | 2018-11-15 |
| JP2023106451A (ja) | 2023-08-01 |
| JP7774319B2 (ja) | 2025-11-21 |
| EP3621660A1 (en) | 2020-03-18 |
| JP2020523983A (ja) | 2020-08-13 |
| AU2018265395B2 (en) | 2025-04-10 |
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