JP2020523356A - 卵巣癌を処置することへの使用のためのチノスタムスチン - Google Patents

卵巣癌を処置することへの使用のためのチノスタムスチン Download PDF

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Publication number
JP2020523356A
JP2020523356A JP2019568650A JP2019568650A JP2020523356A JP 2020523356 A JP2020523356 A JP 2020523356A JP 2019568650 A JP2019568650 A JP 2019568650A JP 2019568650 A JP2019568650 A JP 2019568650A JP 2020523356 A JP2020523356 A JP 2020523356A
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JP
Japan
Prior art keywords
tinostamustine
pharmaceutically acceptable
acceptable salt
ovarian cancer
treatment
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2019568650A
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English (en)
Japanese (ja)
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JP2020523356A5 (enExample
Inventor
トーマス・ヨーク・メーリング
Original Assignee
ユーロ−セルティーク エス．エイ．
ユーロ−セルティーク エス．エイ．
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Application filed by ユーロ−セルティーク エス．エイ．, ユーロ−セルティーク エス．エイ． filed Critical ユーロ−セルティーク エス．エイ．
Publication of JP2020523356A publication Critical patent/JP2020523356A/ja
Publication of JP2020523356A5 publication Critical patent/JP2020523356A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019568650A 2017-06-13 2018-06-13 卵巣癌を処置することへの使用のためのチノスタムスチン Pending JP2020523356A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1709405.3 2017-06-13
GBGB1709405.3A GB201709405D0 (en) 2017-06-13 2017-06-13 Compounds for treating ovarian cancer
PCT/EP2018/065669 WO2018229134A1 (en) 2017-06-13 2018-06-13 Tinostamustine for use in treating ovarian cancer

Publications (2)

Publication Number Publication Date
JP2020523356A true JP2020523356A (ja) 2020-08-06
JP2020523356A5 JP2020523356A5 (enExample) 2021-07-26

Family

ID=59358312

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019568650A Pending JP2020523356A (ja) 2017-06-13 2018-06-13 卵巣癌を処置することへの使用のためのチノスタムスチン

Country Status (14)

Country Link
US (2) US11896583B2 (enExample)
EP (2) EP3638233B1 (enExample)
JP (1) JP2020523356A (enExample)
KR (1) KR102615210B1 (enExample)
AR (1) AR112102A1 (enExample)
AU (1) AU2018285823B2 (enExample)
BR (1) BR112019026486A2 (enExample)
CA (1) CA3067052A1 (enExample)
ES (1) ES2899636T3 (enExample)
GB (1) GB201709405D0 (enExample)
IL (1) IL271019A (enExample)
MX (1) MX388722B (enExample)
TW (1) TW201919617A (enExample)
WO (1) WO2018229134A1 (enExample)

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GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409485D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
WO2018068832A1 (en) 2016-10-11 2018-04-19 Euro-Celtique S.A. Hodgkin lymphoma therapy
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
EP3897626B1 (en) 2018-12-18 2025-09-10 Mundipharma International Corporation Limited Tinostamustine for treating multiple myeloma
CN115253066A (zh) * 2022-07-21 2022-11-01 湖南安泰康成生物科技有限公司 卵巢癌治疗系统以及卵巢癌治疗的交变电场发生装置
US20240252472A1 (en) * 2023-01-25 2024-08-01 Purdue Pharma L.P. Combinations for treating cancer
CN117017962A (zh) * 2023-08-23 2023-11-10 复旦大学附属肿瘤医院 一种hdaci抑制剂在制备治疗卵巢癌药物中的用途

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Also Published As

Publication number Publication date
MX388722B (es) 2025-03-20
KR102615210B1 (ko) 2023-12-18
GB201709405D0 (en) 2017-07-26
IL271019A (en) 2020-01-30
US20200261423A1 (en) 2020-08-20
WO2018229134A1 (en) 2018-12-20
BR112019026486A2 (pt) 2020-07-14
MX2019015207A (es) 2021-12-10
CA3067052A1 (en) 2018-12-20
TW201919617A (zh) 2019-06-01
KR20200014790A (ko) 2020-02-11
AU2018285823B2 (en) 2024-05-30
US20240261265A1 (en) 2024-08-08
ES2899636T3 (es) 2022-03-14
AU2018285823A1 (en) 2019-12-19
EP3638233A1 (en) 2020-04-22
EP3960169A1 (en) 2022-03-02
EP3638233B1 (en) 2021-09-22
AR112102A1 (es) 2019-09-18
US11896583B2 (en) 2024-02-13

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