JP2020518600A5 - - Google Patents
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- JP2020518600A5 JP2020518600A5 JP2019559836A JP2019559836A JP2020518600A5 JP 2020518600 A5 JP2020518600 A5 JP 2020518600A5 JP 2019559836 A JP2019559836 A JP 2019559836A JP 2019559836 A JP2019559836 A JP 2019559836A JP 2020518600 A5 JP2020518600 A5 JP 2020518600A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- preparation according
- approximately
- tigit antibody
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023189493A JP2024016177A (ja) | 2017-05-02 | 2023-11-06 | 単独のおよびプログラム死受容体１（ｐｄ－１）抗体と組み合わされた抗ｔｉｇｉｔ抗体の安定な製剤、ならびにその使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762500278P | 2017-05-02 | 2017-05-02 | |
| US62/500,278 | 2017-05-02 | ||
| PCT/US2018/030516 WO2018204405A1 (en) | 2017-05-02 | 2018-05-01 | Stable formulations of anti-tigit antibodies alone and in combination with programmed death receptor 1 (pd-1) antibodies and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023189493A Division JP2024016177A (ja) | 2017-05-02 | 2023-11-06 | 単独のおよびプログラム死受容体１（ｐｄ－１）抗体と組み合わされた抗ｔｉｇｉｔ抗体の安定な製剤、ならびにその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020518600A JP2020518600A (ja) | 2020-06-25 |
| JP2020518600A5 true JP2020518600A5 (https=) | 2021-05-20 |
| JP7402693B2 JP7402693B2 (ja) | 2023-12-21 |
Family
ID=64016405
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019559836A Active JP7402693B2 (ja) | 2017-05-02 | 2018-05-01 | 単独のおよびプログラム死受容体１（ｐｄ－１）抗体と組み合わされた抗ｔｉｇｉｔ抗体の安定な製剤、ならびにその使用方法 |
| JP2023189493A Pending JP2024016177A (ja) | 2017-05-02 | 2023-11-06 | 単独のおよびプログラム死受容体１（ｐｄ－１）抗体と組み合わされた抗ｔｉｇｉｔ抗体の安定な製剤、ならびにその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023189493A Pending JP2024016177A (ja) | 2017-05-02 | 2023-11-06 | 単独のおよびプログラム死受容体１（ｐｄ－１）抗体と組み合わされた抗ｔｉｇｉｔ抗体の安定な製剤、ならびにその使用方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20200354453A1 (https=) |
| EP (1) | EP3618855A4 (https=) |
| JP (2) | JP7402693B2 (https=) |
| KR (1) | KR102770786B1 (https=) |
| CN (1) | CN110603052A (https=) |
| AU (1) | AU2018261080A1 (https=) |
| BR (1) | BR112019022698A2 (https=) |
| CA (1) | CA3061050A1 (https=) |
| CL (1) | CL2019003145A1 (https=) |
| CO (1) | CO2019012356A2 (https=) |
| IL (1) | IL270175B2 (https=) |
| MA (1) | MA50661A (https=) |
| MX (1) | MX2019013033A (https=) |
| SG (2) | SG10202111905PA (https=) |
| WO (1) | WO2018204405A1 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20131167T1 (hr) | 2007-06-18 | 2014-01-03 | Merck Sharp & Dohme B.V. | Antitijela za humani receptor programirane smrti pd-1 |
| UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| EP3334757A4 (en) * | 2015-08-14 | 2019-04-03 | Merck Sharp & Dohme Corp. | ANTI-Tigit ANTIBODY |
| RS64576B1 (sr) | 2017-05-01 | 2023-10-31 | Agenus Inc | Anti-tigit antitela i postupci njihove primene |
| AU2018263868A1 (en) | 2017-05-02 | 2019-12-12 | Merck Sharp & Dohme Llc | Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies |
| IL277095B2 (en) * | 2018-03-07 | 2025-10-01 | Pfizer | Preparations containing anti-PD-1 antibody |
| KR102885113B1 (ko) | 2018-10-18 | 2025-11-13 | 머크 샤프 앤드 돔 엘엘씨 | 항-rsv 항체의 제제 및 그의 사용 방법 |
| CN120842406A (zh) | 2018-10-31 | 2025-10-28 | 默沙东有限责任公司 | 抗人pd-1抗体晶体及其使用方法 |
| WO2020097141A1 (en) * | 2018-11-07 | 2020-05-14 | Merck Sharp & Dohme Corp. | Stable formulations of programmed death receptor 1 (pd-1) antibodies and methods of use thereof |
| CN113316458B (zh) | 2018-11-07 | 2024-08-02 | 默沙东有限责任公司 | 抗lag3抗体和抗pd-1抗体的共制剂 |
| CN113194925B (zh) * | 2018-12-14 | 2025-03-07 | 莫佛塞斯公司 | 抗体制剂 |
| KR102332847B1 (ko) * | 2019-06-13 | 2021-12-01 | 주식회사 녹십자 | Tigit에 대한 항체 및 이의 용도 |
| EP3999537A1 (en) * | 2019-07-19 | 2022-05-25 | Ichnos Sciences SA | Lyophilized antibody formulation |
| CN112741804A (zh) * | 2019-10-31 | 2021-05-04 | 上海君实生物医药科技股份有限公司 | 含有抗pd-l1抗体的稳定制剂 |
| AU2021211799A1 (en) * | 2020-01-21 | 2022-08-11 | Innovent Biologics (Suzhou) Co., Ltd. | Recombinant fully human anti-TIGIT monoclonal antibody preparations, preparation method therefor and use thereof |
| IL294375B1 (en) * | 2020-01-24 | 2026-02-01 | Regeneron Pharma | Stable antibody formulation |
| CN111995681B (zh) * | 2020-05-09 | 2022-03-08 | 华博生物医药技术（上海）有限公司 | 抗tigit的抗体、其制备方法和应用 |
| BR112022024221A2 (pt) * | 2020-06-02 | 2022-12-20 | Arcus Biosciences Inc | Anticorpos para tigit |
| CN115916348A (zh) | 2020-06-18 | 2023-04-04 | 基因泰克公司 | 使用抗tigit抗体和pd-1轴结合拮抗剂的治疗 |
| CN111718415B (zh) * | 2020-07-03 | 2021-02-23 | 上海洛启生物医药技术有限公司 | 一种抗tigit纳米抗体及其应用 |
| TW202216778A (zh) | 2020-07-15 | 2022-05-01 | 美商安進公司 | Ｔｉｇｉｔ及ｃｄ１１２ｒ阻斷 |
| SMT202500208T1 (it) * | 2020-12-28 | 2025-07-22 | Bristol Myers Squibb Co | Composizioni anticorpali e metodi per il loro uso |
| JP2024501029A (ja) | 2020-12-28 | 2024-01-10 | ブリストル－マイヤーズ スクイブ カンパニー | Ｐｄ１／ｐｄ－ｌ１抗体の皮下投与 |
| AU2022207020A1 (en) * | 2021-01-14 | 2023-08-31 | Shanghai Junshi Biosciences Co., Ltd. | Anti-tigit antibody pharmaceutical composition and application thereof |
| WO2022165001A1 (en) | 2021-01-29 | 2022-08-04 | Merck Sharp & Dohme Llc | Compositions of programmed death receptor 1 (pd-1) antibodies and methods of obtaining the compositions thereof |
| AR125753A1 (es) | 2021-05-04 | 2023-08-09 | Agenus Inc | Anticuerpos anti-tigit, anticuerpos anti-cd96 y métodos de uso de estos |
| IL310217A (en) * | 2021-07-23 | 2024-03-01 | Akeso Biopharma Inc | Pharmaceutical composition and use |
| CN118871463A (zh) | 2021-07-28 | 2024-10-29 | 基因泰克公司 | 用于治疗癌症的方法和组合物 |
| TW202321308A (zh) | 2021-09-30 | 2023-06-01 | 美商建南德克公司 | 使用抗ｔｉｇｉｔ抗體、抗ｃｄ３８抗體及ｐｄ—１軸結合拮抗劑治療血液癌症的方法 |
| CN114106182B (zh) * | 2022-01-26 | 2022-05-17 | 中山康方生物医药有限公司 | 抗tigit的抗体及其用途 |
| EP4482868A4 (en) * | 2022-02-24 | 2026-03-04 | Merck Sharp & Dohme Llc | STABLE FORMULATIONS OF A MULTIVALENT, VHH-BASED, CYTOTOXIC, T-LYMPHOCYTE-ASSOCIATED ANTIGEN 4 (CTLA4) BINDING TO HUMANE CTLA4, AND METHOD FOR USE THEREMISSION |
| WO2023198116A1 (en) * | 2022-04-14 | 2023-10-19 | Beigene Switzerland Gmbh | Stable high concentration arginine formulations containing pd-1 antibody and methods of use thereof |
| EP4537107A2 (en) | 2022-06-07 | 2025-04-16 | Genentech, Inc. | Method for determining the efficacy of a lung cancer treatment comprising an anti-pd-l1 antagonist and an anti-tigit antagonist antibody |
| US20250362305A1 (en) * | 2022-08-04 | 2025-11-27 | Merck Sharp & Dohme Llc | Methods for determining one or more critical quality attributes of co-formulated antibodies |
| WO2024140651A1 (zh) * | 2022-12-27 | 2024-07-04 | 上海复宏汉霖生物技术股份有限公司 | 包含抗tigit抗体的药物制剂 |
| WO2025166550A1 (zh) * | 2024-02-06 | 2025-08-14 | 香港北恒生物科技有限公司 | 工程化细胞及其用途 |
| CN121003695A (zh) * | 2024-05-24 | 2025-11-25 | 百奥泰生物制药股份有限公司 | 抗tigit抗体和抗pd-1抗体联合治疗肿瘤 |
| WO2025248110A1 (en) | 2024-05-31 | 2025-12-04 | Replimune Limited | An oncolytic herpes simplex virus (hsv) and an anti-pd-1 antibody for use in treating braf mutant melanoma |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2081553B1 (en) * | 2006-10-06 | 2020-08-12 | Amgen Inc. | Stable antibody formulations |
| CA2765220A1 (en) * | 2009-07-14 | 2011-01-20 | Biogen Idec Ma Inc. | Methods for inhibiting yellow color and peroxide formation in a composition |
| EP2399604A1 (en) * | 2010-06-25 | 2011-12-28 | F. Hoffmann-La Roche AG | Novel antibody formulation |
| ES2676205T3 (es) * | 2011-03-31 | 2018-07-17 | Merck Sharp & Dohme Corp. | Formulaciones estables de anticuerpos para el receptor PD-1 humano de muerte programada y tratamientos relacionados |
| WO2014031718A1 (en) * | 2012-08-23 | 2014-02-27 | Merck Sharp & Dohme Corp. | Stable formulations of antibodies to tslp |
| CA2916681A1 (en) | 2013-07-16 | 2015-01-22 | Genentech, Inc. | Methods of treating cancer using pd-1 axis binding antagonists and tigit inhibitors |
| AU2015305754B2 (en) * | 2014-08-19 | 2018-10-25 | Merck Sharp & Dohme Llc | Anti-tigit antibodies |
| CN107207594B (zh) * | 2014-12-23 | 2019-05-07 | 百时美施贵宝公司 | 针对tigit的抗体 |
| EP3349792A1 (en) * | 2015-09-14 | 2018-07-25 | Compass Therapeutics LLC | Compositions and methods for treating cancer via antagonism of the cd155/tigit pathway and tgf- |
| US20190010224A1 (en) * | 2015-12-22 | 2019-01-10 | Merck Sharp & Dohme Corp. | Formulations of engineered anti-il-10 antibodies |
| JP2019514889A (ja) * | 2016-04-25 | 2019-06-06 | メディミューン，エルエルシー | 抗ｐｄ−ｌ１および抗ｃｔｌａ−４抗体の共製剤を含む組成物 |
| SG11201910134SA (en) * | 2017-05-02 | 2019-11-28 | Merck Sharp & Dohme | Stable formulations of anti-ctla4 antibodies alone and in combination with programmed death receptor 1 (pd-1) antibodies and methods of use thereof |
-
2018
- 2018-05-01 JP JP2019559836A patent/JP7402693B2/ja active Active
- 2018-05-01 IL IL270175A patent/IL270175B2/en unknown
- 2018-05-01 CA CA3061050A patent/CA3061050A1/en active Pending
- 2018-05-01 US US16/610,188 patent/US20200354453A1/en not_active Abandoned
- 2018-05-01 WO PCT/US2018/030516 patent/WO2018204405A1/en not_active Ceased
- 2018-05-01 MA MA050661A patent/MA50661A/fr unknown
- 2018-05-01 CN CN201880029167.7A patent/CN110603052A/zh active Pending
- 2018-05-01 EP EP18793797.4A patent/EP3618855A4/en active Pending
- 2018-05-01 SG SG10202111905PA patent/SG10202111905PA/en unknown
- 2018-05-01 SG SG11201909941Q patent/SG11201909941QA/en unknown
- 2018-05-01 KR KR1020197035375A patent/KR102770786B1/ko active Active
- 2018-05-01 MX MX2019013033A patent/MX2019013033A/es unknown
- 2018-05-01 AU AU2018261080A patent/AU2018261080A1/en not_active Abandoned
- 2018-05-01 BR BR112019022698A patent/BR112019022698A2/pt unknown
-
2019
- 2019-10-30 CL CL2019003145A patent/CL2019003145A1/es unknown
- 2019-11-01 CO CONC2019/0012356A patent/CO2019012356A2/es unknown
-
2023
- 2023-11-06 JP JP2023189493A patent/JP2024016177A/ja active Pending
-
2024
- 2024-01-25 US US18/422,352 patent/US20240182573A1/en not_active Abandoned
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