JP2020517692A5 - - Google Patents

Download PDF

Info

Publication number
JP2020517692A5
JP2020517692A5 JP2019557872A JP2019557872A JP2020517692A5 JP 2020517692 A5 JP2020517692 A5 JP 2020517692A5 JP 2019557872 A JP2019557872 A JP 2019557872A JP 2019557872 A JP2019557872 A JP 2019557872A JP 2020517692 A5 JP2020517692 A5 JP 2020517692A5
Authority
JP
Japan
Prior art keywords
cells
item
genetically modified
modified
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2019557872A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020517692A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/029993 external-priority patent/WO2018201071A1/en
Publication of JP2020517692A publication Critical patent/JP2020517692A/ja
Publication of JP2020517692A5 publication Critical patent/JP2020517692A5/ja
Priority to JP2023072284A priority Critical patent/JP7526312B2/ja
Priority to JP2024115656A priority patent/JP2024153703A/ja
Withdrawn legal-status Critical Current

Links

JP2019557872A 2017-04-27 2018-04-27 治療剤のin vivo送達のためのB細胞およびその投薬量 Withdrawn JP2020517692A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023072284A JP7526312B2 (ja) 2017-04-27 2023-04-26 治療剤のin vivo送達のためのB細胞およびその投薬量
JP2024115656A JP2024153703A (ja) 2017-04-27 2024-07-19 治療剤のin vivo送達のためのB細胞およびその投薬量

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762491151P 2017-04-27 2017-04-27
US62/491,151 2017-04-27
PCT/US2018/029993 WO2018201071A1 (en) 2017-04-27 2018-04-27 B cells for in vivo delivery of therapeutic agents and dosages thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023072284A Division JP7526312B2 (ja) 2017-04-27 2023-04-26 治療剤のin vivo送達のためのB細胞およびその投薬量

Publications (2)

Publication Number Publication Date
JP2020517692A JP2020517692A (ja) 2020-06-18
JP2020517692A5 true JP2020517692A5 (https=) 2021-05-20

Family

ID=63919297

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019557872A Withdrawn JP2020517692A (ja) 2017-04-27 2018-04-27 治療剤のin vivo送達のためのB細胞およびその投薬量
JP2023072284A Active JP7526312B2 (ja) 2017-04-27 2023-04-26 治療剤のin vivo送達のためのB細胞およびその投薬量
JP2024115656A Pending JP2024153703A (ja) 2017-04-27 2024-07-19 治療剤のin vivo送達のためのB細胞およびその投薬量

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023072284A Active JP7526312B2 (ja) 2017-04-27 2023-04-26 治療剤のin vivo送達のためのB細胞およびその投薬量
JP2024115656A Pending JP2024153703A (ja) 2017-04-27 2024-07-19 治療剤のin vivo送達のためのB細胞およびその投薬量

Country Status (9)

Country Link
US (1) US20220193129A1 (https=)
EP (1) EP3615045A4 (https=)
JP (3) JP2020517692A (https=)
CN (1) CN110709090A (https=)
AU (2) AU2018256887B2 (https=)
BR (1) BR112019022473A2 (https=)
CA (1) CA3061048A1 (https=)
NZ (1) NZ758331A (https=)
WO (1) WO2018201071A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3870604B1 (en) 2018-10-26 2022-11-23 F. Hoffmann-La Roche AG Multispecific antibody screening method using recombinase mediated cassette exchange
US12440513B2 (en) 2019-03-22 2025-10-14 Albany Medical College Methods for improving cognitive function
CN110499336B (zh) * 2019-08-23 2021-10-12 华南农业大学 一种利用小分子化合物提高基因组定点修饰效率的方法
JP7698321B2 (ja) * 2019-11-27 2025-06-25 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム B細胞のcar形質導入とcrispr遺伝子編集との大規模での組み合わせ
EP4236968A4 (en) * 2020-10-30 2024-03-27 Immusoft Corporation Methods of administering genetically modified b cells for in vivo delivery of therapeutic agents
TW202309270A (zh) * 2021-04-19 2023-03-01 美商步行魚醫療公司 用於細胞療法的b細胞擴增之方法
WO2024044697A2 (en) * 2022-08-24 2024-02-29 Walking Fish Therapeutics, Inc. Compositions and methods for treatment of fabry disease
EP4698191A2 (en) * 2023-04-17 2026-02-25 Be Biopharma, Inc. Engineered cell preparations for treatment of niemann pick b disease
EP4698226A2 (en) * 2023-04-17 2026-02-25 Be Biopharma, Inc. Engineered cell preparations for treatment of hemophilia
WO2025106856A1 (en) 2023-11-15 2025-05-22 Immusoft Corporation Migratory modified differentiated b cells for cancer therapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101426523B (zh) * 2006-04-27 2013-03-27 财团法人首尔大学校产学协力财团 基于负载了天然杀伤t细胞的配体、和抗原的b细胞的疫苗
AU2016202625A1 (en) * 2007-07-27 2016-05-19 Armagen Technologies, Inc. Methods and compositions for increasing alpha-iduronidase activity in the CNS
CA2786664C (en) * 2010-01-08 2020-03-10 Immusoft Corporation Vectors and methods for transducing b cells
PT2971039T (pt) * 2013-03-14 2020-05-06 Immusoft Corp Métodos para diferenciação e transdução in vitro de células b de memória com vetores virais pseudotipados vsv-g
CN111909278B (zh) * 2014-01-27 2024-04-09 分子模板公司 Mhc i类表位递送多肽
DK3234107T3 (da) * 2014-12-19 2022-10-17 Immusoft Corp B-celler til in vivo-levering af terapeutiske midler
AU2016243052C1 (en) * 2015-04-03 2022-11-24 Dana-Farber Cancer Institute, Inc. Composition and methods of genome editing of B-cells
HK1256341A1 (zh) * 2015-05-15 2019-09-20 明尼苏达大学董事会 用於治疗性递送到中枢神经系统的腺相关物
CN111936617A (zh) * 2018-03-16 2020-11-13 益缪索夫特公司 经遗传工程化以分泌卵泡抑素的b细胞以及使用所述b细胞来治疗卵泡抑素相关的疾病、病况、病症及增强肌肉生长和力量的方法

Similar Documents

Publication Publication Date Title
JP2020517692A5 (https=)
Wang et al. Transcription factors associated with IL-15 cytokine signaling during NK cell development
JP7495695B2 (ja) 幹細胞の免疫制御作用を調節する方法
US12540167B2 (en) Cytokine combination
CN111658670B (zh) 溶瘤腺病毒载体与过继t细胞治疗组合物及其用途
CN106659742B (zh) 表达免疫应答刺激细胞因子以吸引和/或激活免疫细胞的基因修饰间充质干细胞
CN102174479B (zh) 靶向性治疗人肿瘤的溶肿瘤腺病毒及其应用
US12409217B2 (en) Administering a lymphocytic choriomeningtitis virus (LCMV) with improved tumor regression properties
Wang et al. Viral vectors expressing interleukin 2 for cancer immunotherapy
CN107793482A (zh) 嵌合抗原受体及其基因和重组表达载体、car133‑nkt 细胞及其制备方法和应用
JPH07503455A (ja) 癌のリンホカイン遺伝子療法
AU2020242520B2 (en) Method for the expansion and differentiation of T lymphocytes and NK cells in adoptive transfer therapies
JP2021515576A5 (https=)
JPH09508116A (ja) 末梢血単核細胞溶解活性を刺激するためのil−10の使用
US20060153805A1 (en) Viral vectors and the use of the same for gene therapy
JP6687246B2 (ja) 改変型免疫細胞、改変型免疫細胞の製造方法、およびこれらの利用
CN111499766B (zh) 针对慢性淋巴细胞白血病的免疫效应细胞、其制备方法和应用
WO2018009506A1 (en) Erythroid-specific promoter and method of use thereof
US20180066253A1 (en) Methods and compositions for modifying endothelial cells
US7323450B2 (en) Complex immuno-gene medical composition for inhibiting tumor cells
JPWO2019178613A5 (https=)
RU2019136194A (ru) В-клетки для доставки терапевтических средств in vivo и их дозы
JPWO2022094284A5 (https=)
Kerzel L’IFN-alpha secreto da macrofagi ingegnerizzati in vivo riduce le metastasi al fegato e induce l’attivazione di processi contro regolatori che ne limitano l’efficacia
CN119799717A (zh) 核酸形式il-9联合免疫检查点药物的制剂组合与应用