JP2023138660A5 - - Google Patents
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- JP2023138660A5 JP2023138660A5 JP2023129040A JP2023129040A JP2023138660A5 JP 2023138660 A5 JP2023138660 A5 JP 2023138660A5 JP 2023129040 A JP2023129040 A JP 2023129040A JP 2023129040 A JP2023129040 A JP 2023129040A JP 2023138660 A5 JP2023138660 A5 JP 2023138660A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- recombinant
- population
- subject
- follistatin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025203919A JP2026026184A (ja) | 2018-03-16 | 2025-11-26 | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862644362P | 2018-03-16 | 2018-03-16 | |
| US201862644356P | 2018-03-16 | 2018-03-16 | |
| US62/644,362 | 2018-03-16 | ||
| US62/644,356 | 2018-03-16 | ||
| PCT/US2019/022821 WO2019178613A1 (en) | 2018-03-16 | 2019-03-18 | B cells genetically engineered to secrete follistatin and methods of using the same to treat follistatin-related diseases, conditions, disorders and to enhance muscle growth and strength |
| JP2020548962A JP2021515576A (ja) | 2018-03-16 | 2019-03-18 | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020548962A Division JP2021515576A (ja) | 2018-03-16 | 2019-03-18 | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025203919A Division JP2026026184A (ja) | 2018-03-16 | 2025-11-26 | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023138660A JP2023138660A (ja) | 2023-10-02 |
| JP2023138660A5 true JP2023138660A5 (https=) | 2025-03-03 |
Family
ID=65995892
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020548962A Pending JP2021515576A (ja) | 2018-03-16 | 2019-03-18 | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
| JP2023129040A Withdrawn JP2023138660A (ja) | 2018-03-16 | 2023-08-08 | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
| JP2025203919A Pending JP2026026184A (ja) | 2018-03-16 | 2025-11-26 | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020548962A Pending JP2021515576A (ja) | 2018-03-16 | 2019-03-18 | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025203919A Pending JP2026026184A (ja) | 2018-03-16 | 2025-11-26 | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210047619A1 (https=) |
| EP (1) | EP3765601A1 (https=) |
| JP (3) | JP2021515576A (https=) |
| CN (1) | CN111936617A (https=) |
| AU (2) | AU2019233929B2 (https=) |
| CA (1) | CA3093716A1 (https=) |
| WO (1) | WO2019178613A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014152832A1 (en) | 2013-03-14 | 2014-09-25 | Immusoft Corporation | Methods for in vitro memory b cell differentiation and transduction with vsv-g pseudotyped viral vectors |
| BR112019022473A2 (pt) * | 2017-04-27 | 2020-10-20 | Immusoft Corporation | células b para liberação in vivo de agentes terapêuticos e dosagens destas |
| WO2020084034A1 (en) | 2018-10-26 | 2020-04-30 | F. Hoffmann-La Roche Ag | Multispecific antibody screening method using recombinase mediated cassette exchange |
| EP3914265A4 (en) * | 2019-01-23 | 2023-02-01 | The General Hospital Corporation | B-CELL IMMUNOTHERAPY |
| CA3094859A1 (en) * | 2020-10-01 | 2022-04-01 | Entos Pharmaceuticals Inc. | Proteolipid vesicles formulated with fusion associated small transmembrane proteins |
| WO2025047766A1 (ja) * | 2023-08-29 | 2025-03-06 | 富士フイルム株式会社 | ウイルスの製造方法および細胞への核酸導入方法 |
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| FR901228A (fr) | 1943-01-16 | 1945-07-20 | Deutsche Edelstahlwerke Ag | Système d'aimant à entrefer annulaire |
| US4937190A (en) | 1987-10-15 | 1990-06-26 | Wisconsin Alumni Research Foundation | Translation enhancer |
| US5124259A (en) | 1989-08-23 | 1992-06-23 | Mitsui Toatsu Chemicals, Inc. | Method for electroporation |
| DE4223128C2 (de) | 1991-07-15 | 1995-06-14 | Handtmann Albert Maschf | Verfahren und Vorrichtung zum Vereinzeln und Aufbringen einer Darmraupe auf ein Füllrohr |
| US5283185A (en) | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
| US5420032A (en) | 1991-12-23 | 1995-05-30 | Universitge Laval | Homing endonuclease which originates from chlamydomonas eugametos and recognizes and cleaves a 15, 17 or 19 degenerate double stranded nucleotide sequence |
| US5792632A (en) | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| WO1995004521A1 (en) | 1993-08-10 | 1995-02-16 | W.L. Gore & Associates, Inc. | Cell encapsulating device |
| US5651981A (en) | 1994-03-29 | 1997-07-29 | Northwestern University | Cationic phospholipids for transfection |
| WO1996039993A1 (en) | 1995-06-07 | 1996-12-19 | Gore Hybrid Technologies, Inc. | An implantable containment apparatus for a therapeutical device and method for loading and reloading the device therein |
| US5626561A (en) | 1995-06-07 | 1997-05-06 | Gore Hybrid Technologies, Inc. | Implantable containment apparatus for a therapeutical device and method for loading and reloading the device therein |
| WO1997010807A1 (en) | 1995-09-22 | 1997-03-27 | Gore Hybrid Technologies, Inc. | Improved cell encapsulation device |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US6218181B1 (en) | 1998-03-18 | 2001-04-17 | The Salk Institute For Biological Studies | Retroviral packaging cell line |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| CA2438500C (en) | 2001-02-19 | 2009-09-08 | Pola Chemical Industries Inc. | Composition for electroporation |
| WO2003087341A2 (en) | 2002-01-23 | 2003-10-23 | The University Of Utah Research Foundation | Targeted chromosomal mutagenesis using zinc finger nucleases |
| CN1929734A (zh) * | 2002-02-21 | 2007-03-14 | 惠氏公司 | 含卵泡抑素区的蛋白质 |
| WO2003080809A2 (en) | 2002-03-21 | 2003-10-02 | Sangamo Biosciences, Inc. | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
| EP2806025B1 (en) | 2002-09-05 | 2019-04-03 | California Institute of Technology | Use of zinc finger nucleases to stimulate gene targeting |
| US8409861B2 (en) | 2003-08-08 | 2013-04-02 | Sangamo Biosciences, Inc. | Targeted deletion of cellular DNA sequences |
| US20070134796A1 (en) | 2005-07-26 | 2007-06-14 | Sangamo Biosciences, Inc. | Targeted integration and expression of exogenous nucleic acid sequences |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| JP4688483B2 (ja) * | 2004-04-15 | 2011-05-25 | 株式会社テクノネットワーク四国 | フォリスタチン変異体ポリペプチド |
| CN109045307A (zh) * | 2004-06-01 | 2018-12-21 | 健泰科生物技术公司 | 抗体-药物偶联物和方法 |
| AU2005287278B2 (en) | 2004-09-16 | 2011-08-04 | Sangamo Biosciences, Inc. | Compositions and methods for protein production |
| CA2538208A1 (en) * | 2005-05-04 | 2006-11-04 | Universite Laval | Modulation of myostatin and use thereof in cell transplantation-based treatment of muscle disease |
| ES2582091T3 (es) | 2005-10-18 | 2016-09-09 | Precision Biosciences | Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas |
| US7799555B2 (en) | 2006-02-10 | 2010-09-21 | Bio-Rad Laboratories, Inc. | Apparatus for high-throughput electroporation |
| EP2205752B1 (en) | 2007-10-25 | 2016-08-10 | Sangamo BioSciences, Inc. | Methods and compositions for targeted integration |
| US8551780B2 (en) | 2008-02-01 | 2013-10-08 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | Electroporation buffer composition and method of use |
| CA2720903C (en) | 2008-04-14 | 2019-01-15 | Sangamo Biosciences, Inc. | Linear donor constructs for targeted integration |
| SG191561A1 (en) | 2008-08-22 | 2013-07-31 | Sangamo Biosciences Inc | Methods and compositions for targeted single-stranded cleavage and targeted integration |
| US8133727B2 (en) | 2008-11-21 | 2012-03-13 | California Institute Of Technology | In vitro human B lymphopoiesis culture system |
| US8586526B2 (en) | 2010-05-17 | 2013-11-19 | Sangamo Biosciences, Inc. | DNA-binding proteins and uses thereof |
| US9074223B2 (en) | 2010-01-08 | 2015-07-07 | Immusoft Corporation | Vectors and methods for transducing B cells |
| EP2660318A1 (en) | 2010-02-09 | 2013-11-06 | Sangamo BioSciences, Inc. | Targeted genomic modification with partially single-stranded donor molecules |
| US8633029B2 (en) | 2010-03-15 | 2014-01-21 | Yamaguchi University | Agent for improving gene transfer efficiency to mammalian cells |
| JP6188728B2 (ja) * | 2012-02-07 | 2017-08-30 | グローバル・バイオ・セラピューティクス・インコーポレイテッドGlobal Bio Therapeutics,Inc. | 核酸送達の区画化方法ならびにその組成物および使用 |
| ES2715710T3 (es) * | 2013-01-25 | 2019-06-05 | Shire Human Genetic Therapies | Folistatina en el tratamiento de la distrofía muscular de Duchenne |
| WO2014152832A1 (en) | 2013-03-14 | 2014-09-25 | Immusoft Corporation | Methods for in vitro memory b cell differentiation and transduction with vsv-g pseudotyped viral vectors |
| US10611837B2 (en) * | 2014-04-10 | 2020-04-07 | Seattle Children's Hospital | Transgene genetic tags and methods of use |
| US10010498B2 (en) * | 2014-06-04 | 2018-07-03 | Acceleron Pharma Inc. | Methods for treatment of amyotrophic lateral sclerosis with follistatin fusion proteins |
| EA202090632A1 (ru) * | 2014-06-04 | 2020-07-31 | Акселерон Фарма Инк. | Способы и композиции для лечения расстройств с использованием фоллистатиновых полипептидов |
| US10842886B2 (en) * | 2014-10-10 | 2020-11-24 | Research Institute At Nationwide Children's Hospital | Guided injections for AAV gene transfer to muscle |
| DK3234107T3 (da) * | 2014-12-19 | 2022-10-17 | Immusoft Corp | B-celler til in vivo-levering af terapeutiske midler |
| WO2016118780A1 (en) * | 2015-01-21 | 2016-07-28 | Fred Hutchinson Cancer Research Center | Point-of-care and/or portable platform for gene therapy |
| CA2981077A1 (en) * | 2015-04-03 | 2016-10-06 | Dana-Farber Cancer Institute, Inc. | Composition and methods of genome editing of b-cells |
| CA2992551A1 (en) * | 2015-07-21 | 2017-01-26 | Novartis Ag | Methods for improving the efficacy and expansion of immune cells |
-
2019
- 2019-03-18 EP EP19714953.7A patent/EP3765601A1/en active Pending
- 2019-03-18 CA CA3093716A patent/CA3093716A1/en active Pending
- 2019-03-18 JP JP2020548962A patent/JP2021515576A/ja active Pending
- 2019-03-18 CN CN201980019277.XA patent/CN111936617A/zh active Pending
- 2019-03-18 WO PCT/US2019/022821 patent/WO2019178613A1/en not_active Ceased
- 2019-03-18 AU AU2019233929A patent/AU2019233929B2/en active Active
- 2019-03-18 US US16/981,618 patent/US20210047619A1/en active Pending
-
2023
- 2023-08-08 JP JP2023129040A patent/JP2023138660A/ja not_active Withdrawn
-
2025
- 2025-08-29 AU AU2025223865A patent/AU2025223865A1/en active Pending
- 2025-11-26 JP JP2025203919A patent/JP2026026184A/ja active Pending
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