JP2020517283A5 - - Google Patents
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- JP2020517283A5 JP2020517283A5 JP2019557794A JP2019557794A JP2020517283A5 JP 2020517283 A5 JP2020517283 A5 JP 2020517283A5 JP 2019557794 A JP2019557794 A JP 2019557794A JP 2019557794 A JP2019557794 A JP 2019557794A JP 2020517283 A5 JP2020517283 A5 JP 2020517283A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- neural
- differentiation
- tissues
- pluripotent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17168051.5A EP3395942A1 (en) | 2017-04-25 | 2017-04-25 | Bi- or multi-differentiated organoid |
| EP17168051.5 | 2017-04-25 | ||
| PCT/EP2018/060559 WO2018197544A1 (en) | 2017-04-25 | 2018-04-25 | Bi- or multi-differentiated organoid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020517283A JP2020517283A (ja) | 2020-06-18 |
| JP2020517283A5 true JP2020517283A5 (enExample) | 2021-04-30 |
| JP7248590B2 JP7248590B2 (ja) | 2023-03-29 |
Family
ID=58672346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019557794A Active JP7248590B2 (ja) | 2017-04-25 | 2018-04-25 | 二分化または多分化オルガノイド |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20210095260A1 (enExample) |
| EP (2) | EP3395942A1 (enExample) |
| JP (1) | JP7248590B2 (enExample) |
| KR (1) | KR102692498B1 (enExample) |
| CN (2) | CN119101651A (enExample) |
| AU (1) | AU2018260183B2 (enExample) |
| CA (1) | CA3061412A1 (enExample) |
| ES (1) | ES3068551T3 (enExample) |
| SG (1) | SG11201909470TA (enExample) |
| WO (1) | WO2018197544A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| ES2860423T3 (es) | 2014-05-28 | 2021-10-05 | Childrens Hospital Med Ct | Métodos y sistemas para convertir células precursoras en tejidos gástricos mediante diferenciación dirigida |
| CA2963704A1 (en) | 2014-10-17 | 2016-04-21 | Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
| CN109415685B (zh) | 2016-05-05 | 2023-07-04 | 儿童医院医疗中心 | 用于体外制造胃底组织的方法和与其相关的组合物 |
| SG10202104575WA (en) | 2016-11-04 | 2021-06-29 | Childrens Hospital Med Ct | Liver organoid compositions and methods of making and using same |
| CA3045145A1 (en) | 2016-12-05 | 2018-06-14 | Children's Hospital Medical Center | Colonic organoids and methods of making and using same |
| US12281334B2 (en) | 2017-04-14 | 2025-04-22 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| EP3658666A4 (en) * | 2017-07-28 | 2021-04-28 | Memorial Sloan-Kettering Cancer Center | PRODUCTION OF A TOPOGRAPHICAL ORGANIZATION IN A THREE-DIMENSIONAL TISSUE CULTURE |
| WO2019074793A1 (en) | 2017-10-10 | 2019-04-18 | Children's Hospital Medical Center | OESOPHAGIAN TISSUE COMPOSITIONS AND / OR ORGANOIDS AND METHODS OF MAKING SAME |
| JP7702784B2 (ja) * | 2017-12-04 | 2025-07-04 | ザ アドミニストレイターズ オブ ザ テューレイン エデュケイショナル ファンド | スフェロイドを用いた細胞システムならびにそれらの製造方法及び使用方法 |
| US12379372B2 (en) | 2017-12-21 | 2025-08-05 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| CA3106634A1 (en) * | 2018-07-26 | 2020-01-30 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| CN112823012A (zh) | 2018-09-12 | 2021-05-18 | 儿童医院医学中心 | 用于产生造血干细胞及其衍生物的类器官组合物 |
| WO2020160371A1 (en) | 2019-02-01 | 2020-08-06 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| US12534709B2 (en) | 2019-05-31 | 2026-01-27 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| CA3141807A1 (en) | 2019-05-31 | 2020-12-03 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| US20230287357A1 (en) * | 2020-07-06 | 2023-09-14 | President And Fellows Of Harvard College | Programmable organoids and methods of producing the same via orthogonal differentiation and bioprinting |
| WO2022154080A1 (ja) * | 2021-01-15 | 2022-07-21 | 国立大学法人東京大学 | 複雑な活動と可塑性を示すインビトロ神経回路組織、その神経活動の観察装置およびこれを用いた物質のスクリーニング方法 |
| DE102021132190A1 (de) * | 2021-12-07 | 2023-06-22 | Eberhard Karls Universität Tübingen, Körperschaft des öffentlichen Rechts | Biokompatible Strukturen zur Verbindung und Kultivierung von biologischem Material |
| HUP2200189A2 (hu) * | 2022-05-30 | 2023-12-28 | Biotalentum Tudasfejlesztoe Kft | Új, riportert stabilan expresszáló humán indukált pluripotens õssejt |
| EP4286513A1 (en) | 2022-06-03 | 2023-12-06 | IMBA-Institut für Molekulare Biotechnologie GmbH | Triple tissue culture fusion |
| CN116286342B (zh) * | 2022-12-23 | 2025-10-28 | 山东大学 | 一种类人脑皮质芯片、3d打印类人脑皮质的方法及应用 |
| CN116129193B (zh) * | 2023-02-27 | 2024-06-11 | 重庆大学附属肿瘤医院 | 一种类器官生长预测方法、系统及设备 |
| CN118530833B (zh) * | 2024-04-02 | 2024-11-29 | 武汉大学 | 一种同步共分化的多组织或多类器官模型及其构建方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4829000A (en) | 1985-08-30 | 1989-05-09 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Reconstituted basement membrane complex with biological activity |
| DE10003521A1 (de) | 2000-01-27 | 2001-08-09 | Medigene Ag | Vorrichtung zum Herstellen eines dreidimensionalen Matrixkörpers, Multi-Well-Platte, Lösung zum Kultivieren von Säugerkardiomyocyten, Verfahren zum Kultivieren einer Zellkultur, Vorrichtung für die Messung isometrischer Kraftparameter von Zellkulturen sowie Verfahren zum meßbaren Verfolgen von Kontraktionen eines in eine Trägersubstanz eingelagerten Zellgewebes |
| US8021876B2 (en) | 2001-11-15 | 2011-09-20 | Children's Medical Center Corporation | Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof |
| WO2004084950A2 (en) | 2003-03-24 | 2004-10-07 | Case Western Reserve University | Cell targeting methods and compositions |
| US20100196923A1 (en) | 2007-08-14 | 2010-08-05 | Anthony Atala | Pluripotent adult stem cells |
| EP2028268A1 (en) * | 2007-08-20 | 2009-02-25 | Université Libre De Bruxelles | Generation of neuronal cells from pluripotent stem cells |
| US20110143433A1 (en) | 2008-03-17 | 2011-06-16 | Agency For Science, Technology And Research | Microcarriers for Stem Cell Culture |
| US10793830B2 (en) * | 2009-11-05 | 2020-10-06 | Riken | Method for producing retinal tissue in vitro |
| US20130149287A1 (en) * | 2010-07-30 | 2013-06-13 | Cambridge Enterprise Limited | Corticogenesis of Human Pluripotent Cells |
| EP2893000B1 (en) | 2012-09-03 | 2019-04-10 | Novo Nordisk A/S | Generation of pancreatic endoderm from pluripotent stem cells using small molecules |
| EP2743345A1 (en) * | 2012-12-13 | 2014-06-18 | IMBA-Institut für Molekulare Biotechnologie GmbH | Three dimensional heterogeneously differentiated tissue culture |
| KR101381798B1 (ko) * | 2013-02-27 | 2014-04-07 | 씨제이제일제당 (주) | 신규 박테리오파지 및 이를 포함하는 항균 조성물 |
| US9677085B2 (en) * | 2013-03-18 | 2017-06-13 | Massachusetts Institute Of Technology | Engineering a heterogeneous tissue from pluripotent stem cells |
| JP6756610B2 (ja) * | 2013-04-26 | 2020-09-16 | メモリアル スローン ケタリング キャンサー センター | 多分化能細胞および多能性細胞の分化を方向付けることによって発生させる皮質介在ニューロンおよびその他のニューロン細胞 |
| US10794802B2 (en) * | 2013-09-20 | 2020-10-06 | California Institute Of Technology | Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high resolution intact circuit mapping and phenotyping |
| US11767507B2 (en) * | 2013-11-08 | 2023-09-26 | The Mclean Hospital Corporation | Methods for efficient generation of GABAergic interneurons from pluripotent stem cells |
| KR102317610B1 (ko) | 2013-11-22 | 2021-10-26 | 고쿠리쓰 겐큐 가이하쓰 호징 리가가쿠 겐큐소 | 종뇌 또는 그 선구 조직의 제조 방법 |
| US10081792B2 (en) * | 2014-12-31 | 2018-09-25 | Wisconsin Alumni Research Foundation | Derivation of human microglia from pluripotent stem cells |
| AU2016226178B2 (en) * | 2015-03-03 | 2021-07-29 | President And Fellows Of Harvard College | Methods of generating functional human tissue |
| US10087417B2 (en) * | 2015-04-22 | 2018-10-02 | William J. Freed | Three-dimensional model of human cortex |
| US10081791B2 (en) * | 2015-05-07 | 2018-09-25 | William J. Freed | Modeling connections between dopaminergic neurons and the cerebral cortex |
| LU92845B1 (en) * | 2015-10-08 | 2017-05-02 | Univ Du Luxembourg Campus Belval | Means and methods for generating midbrain organoids |
| US10597623B2 (en) * | 2015-11-13 | 2020-03-24 | The Johns Hopkins University | Multiwell cell culture system having rotating shafts for mixing culture media and method of use thereof |
| WO2017117547A1 (en) * | 2015-12-31 | 2017-07-06 | President And Fellows Of Harvard College | Methods for generating neural tissue and uses thereof |
| SG11201807487WA (en) * | 2016-03-14 | 2018-09-27 | Agency Science Tech & Res | Generation of midbrain-specific organoids from human pluripotent stem cells |
| FR3058892B1 (fr) * | 2016-11-23 | 2021-04-09 | Univ Bordeaux | Unite de tissu neural et utilisation d'une telle unite pour l'implantation dans le systeme nerveux d'un mammifere |
| US10676715B2 (en) * | 2017-03-28 | 2020-06-09 | The Board Of Trustees Of The Leland Stanford Junior University | Assembly of functionally integrated human forebrain spheroids and methods of use thereof |
| KR102695118B1 (ko) * | 2017-03-29 | 2024-08-16 | 이스트만 케미칼 컴파니 | 위치-선택적으로 치환된 셀룰로스 에스터 |
| GB201900930D0 (en) * | 2019-01-23 | 2019-03-13 | Res & Innovation Uk | Choroid plexus organoids and methods for productions thereof |
| WO2020247336A1 (en) * | 2019-06-03 | 2020-12-10 | The Regents Of The University Of California | Pifithrin analogues and methods of treating rett syndrome |
-
2017
- 2017-04-25 EP EP17168051.5A patent/EP3395942A1/en not_active Withdrawn
-
2018
- 2018-04-25 ES ES18720229T patent/ES3068551T3/es active Active
- 2018-04-25 SG SG11201909470T patent/SG11201909470TA/en unknown
- 2018-04-25 JP JP2019557794A patent/JP7248590B2/ja active Active
- 2018-04-25 CA CA3061412A patent/CA3061412A1/en active Pending
- 2018-04-25 CN CN202411042018.8A patent/CN119101651A/zh active Pending
- 2018-04-25 AU AU2018260183A patent/AU2018260183B2/en active Active
- 2018-04-25 CN CN201880027801.3A patent/CN110573609A/zh active Pending
- 2018-04-25 KR KR1020197034778A patent/KR102692498B1/ko active Active
- 2018-04-25 US US16/608,719 patent/US20210095260A1/en active Pending
- 2018-04-25 EP EP18720229.6A patent/EP3615661B1/en active Active
- 2018-04-25 WO PCT/EP2018/060559 patent/WO2018197544A1/en not_active Ceased
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