JP2014508527A5 - - Google Patents
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- JP2014508527A5 JP2014508527A5 JP2013557133A JP2013557133A JP2014508527A5 JP 2014508527 A5 JP2014508527 A5 JP 2014508527A5 JP 2013557133 A JP2013557133 A JP 2013557133A JP 2013557133 A JP2013557133 A JP 2013557133A JP 2014508527 A5 JP2014508527 A5 JP 2014508527A5
- Authority
- JP
- Japan
- Prior art keywords
- cell population
- cells
- cell
- markers
- subpopulations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 26
- 238000000034 method Methods 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 3
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 2
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 2
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 2
- 208000037979 autoimmune inflammatory disease Diseases 0.000 claims 2
- 239000006285 cell suspension Substances 0.000 claims 2
- 208000037976 chronic inflammation Diseases 0.000 claims 2
- 208000037893 chronic inflammatory disorder Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 2
- 210000000056 organ Anatomy 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- -1 CD11c Proteins 0.000 claims 1
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 1
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 1
- 101001046686 Homo sapiens Integrin alpha-M Proteins 0.000 claims 1
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 claims 1
- 102100022338 Integrin alpha-M Human genes 0.000 claims 1
- 102100022297 Integrin alpha-X Human genes 0.000 claims 1
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 claims 1
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 1
- 230000001464 adherent effect Effects 0.000 claims 1
- 210000000577 adipose tissue Anatomy 0.000 claims 1
- 239000006143 cell culture medium Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 210000000265 leukocyte Anatomy 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11157930.6 | 2011-03-11 | ||
| EP11157930 | 2011-03-11 | ||
| PCT/EP2012/054251 WO2012123401A1 (en) | 2011-03-11 | 2012-03-12 | Cell populations having immunoregulatory activity, method for isolation and uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014508527A JP2014508527A (ja) | 2014-04-10 |
| JP2014508527A5 true JP2014508527A5 (enExample) | 2015-04-23 |
Family
ID=45812789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013557133A Pending JP2014508527A (ja) | 2011-03-11 | 2012-03-12 | 免疫調節活性を有する細胞集団、単離方法および使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140154227A1 (enExample) |
| EP (1) | EP2683813A1 (enExample) |
| JP (1) | JP2014508527A (enExample) |
| KR (1) | KR20140016933A (enExample) |
| ES (1) | ES2479565T1 (enExample) |
| WO (1) | WO2012123401A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| SG165418A1 (en) | 2005-09-23 | 2010-10-28 | Cellerix Sl | Cell populations having immunoregulatory activity, method for isolation and uses |
| EP3013943B1 (en) * | 2013-06-25 | 2019-04-10 | TiGenix, S.A.U. | Cell populations having immunoregulatory activity, methods for the preparation and uses thereof |
| WO2015014988A1 (en) * | 2013-08-01 | 2015-02-05 | Fundacion Pública Andaluza Progreso Y Salud | Method for predicting treatment response and test for safe use of mesenchymal stem cells on inflammatory diseases. |
| KR101931420B1 (ko) * | 2014-05-01 | 2018-12-20 | 가부시키가이샤 시마즈세이사쿠쇼 | 세포의 분화 상태의 평가 방법 |
| EP3160480B1 (en) * | 2014-06-30 | 2020-09-09 | TiGenix, S.A.U. | Mesenchymal stromal cells for treating rheumatoid arthritis |
| GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| CN110592002B (zh) * | 2019-10-10 | 2021-04-02 | 山东大学齐鲁医院 | 一种用于单细胞测序的膀胱尿路上皮单细胞悬液的制备方法及应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005056777A1 (ja) * | 2003-12-10 | 2005-06-23 | Hitachi Medical Corporation | 接着性幹細胞分画並びにその分離方法、品質管理方法及び品質管理装置 |
| JP4980211B2 (ja) * | 2004-05-12 | 2012-07-18 | ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ | 細胞単離方法 |
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| SG165418A1 (en) * | 2005-09-23 | 2010-10-28 | Cellerix Sl | Cell populations having immunoregulatory activity, method for isolation and uses |
| GB0820397D0 (en) * | 2008-11-07 | 2008-12-17 | Cellerix Sa | Cells, nucleic acid constructs, cells comprising said constructs and methods utilizing said cells in the treatment of diseases |
-
2012
- 2012-03-12 JP JP2013557133A patent/JP2014508527A/ja active Pending
- 2012-03-12 WO PCT/EP2012/054251 patent/WO2012123401A1/en not_active Ceased
- 2012-03-12 EP EP12708032.3A patent/EP2683813A1/en not_active Withdrawn
- 2012-03-12 KR KR1020137026776A patent/KR20140016933A/ko not_active Withdrawn
- 2012-03-12 ES ES12708032.3T patent/ES2479565T1/es active Pending
- 2012-03-12 US US14/004,004 patent/US20140154227A1/en not_active Abandoned
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