JP2011529706A5 - - Google Patents
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- Publication number
- JP2011529706A5 JP2011529706A5 JP2011522168A JP2011522168A JP2011529706A5 JP 2011529706 A5 JP2011529706 A5 JP 2011529706A5 JP 2011522168 A JP2011522168 A JP 2011522168A JP 2011522168 A JP2011522168 A JP 2011522168A JP 2011529706 A5 JP2011529706 A5 JP 2011529706A5
- Authority
- JP
- Japan
- Prior art keywords
- population
- mesenchymal stromal
- stromal cells
- cells
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000002536 stromal cell Anatomy 0.000 claims description 45
- 239000006166 lysate Substances 0.000 claims description 24
- 239000001963 growth medium Substances 0.000 claims description 23
- 210000004027 cell Anatomy 0.000 claims description 21
- 238000000034 method Methods 0.000 claims description 21
- 230000001464 adherent effect Effects 0.000 claims description 20
- 210000001185 bone marrow Anatomy 0.000 claims description 14
- 238000012258 culturing Methods 0.000 claims description 14
- 210000001519 tissue Anatomy 0.000 claims description 14
- 208000012902 Nervous system disease Diseases 0.000 claims description 7
- 208000027866 inflammatory disease Diseases 0.000 claims description 7
- 208000017169 kidney disease Diseases 0.000 claims description 7
- 239000002609 medium Substances 0.000 claims description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 6
- 208000035475 disorder Diseases 0.000 claims description 6
- 238000005119 centrifugation Methods 0.000 claims description 5
- 239000003634 thrombocyte concentrate Substances 0.000 claims description 5
- 241000283690 Bos taurus Species 0.000 claims description 4
- 230000001605 fetal effect Effects 0.000 claims description 4
- 230000002757 inflammatory effect Effects 0.000 claims description 3
- 230000000926 neurological effect Effects 0.000 claims description 3
- 102100022464 5'-nucleotidase Human genes 0.000 claims description 2
- 208000009304 Acute Kidney Injury Diseases 0.000 claims description 2
- 101100347633 Drosophila melanogaster Mhc gene Proteins 0.000 claims description 2
- 102100037241 Endoglin Human genes 0.000 claims description 2
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims description 2
- 101000678236 Homo sapiens 5'-nucleotidase Proteins 0.000 claims description 2
- 101000881679 Homo sapiens Endoglin Proteins 0.000 claims description 2
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims description 2
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 claims description 2
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims description 2
- 101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 claims description 2
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 claims description 2
- 208000034486 Multi-organ failure Diseases 0.000 claims description 2
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims description 2
- 208000033626 Renal failure acute Diseases 0.000 claims description 2
- 102100033523 Thy-1 membrane glycoprotein Human genes 0.000 claims description 2
- 201000011040 acute kidney failure Diseases 0.000 claims description 2
- 208000012998 acute renal failure Diseases 0.000 claims description 2
- 239000000427 antigen Substances 0.000 claims description 2
- 102000036639 antigens Human genes 0.000 claims description 2
- 108091007433 antigens Proteins 0.000 claims description 2
- 208000020832 chronic kidney disease Diseases 0.000 claims description 2
- 208000022831 chronic renal failure syndrome Diseases 0.000 claims description 2
- 230000002163 immunogen Effects 0.000 claims description 2
- 208000029744 multiple organ dysfunction syndrome Diseases 0.000 claims description 2
- 235000021110 pickles Nutrition 0.000 claims description 2
- 102000004169 proteins and genes Human genes 0.000 claims description 2
- 108090000623 proteins and genes Proteins 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 8
- 208000010718 Multiple Organ Failure Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8603308P | 2008-08-04 | 2008-08-04 | |
| US61/086,033 | 2008-08-04 | ||
| PCT/US2009/052733 WO2010017216A2 (en) | 2008-08-04 | 2009-08-04 | Mesenchymal stromal cell populations and methods of isolating and using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011529706A JP2011529706A (ja) | 2011-12-15 |
| JP2011529706A5 true JP2011529706A5 (enExample) | 2012-09-20 |
Family
ID=41664170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011522168A Pending JP2011529706A (ja) | 2008-08-04 | 2009-08-04 | 間充織間質細胞集団、ならびにそれを単離および使用する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110293576A1 (enExample) |
| EP (1) | EP2321408A4 (enExample) |
| JP (1) | JP2011529706A (enExample) |
| AU (1) | AU2009279736A1 (enExample) |
| CA (1) | CA2736353A1 (enExample) |
| WO (1) | WO2010017216A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3266453A1 (en) | 2008-07-03 | 2018-01-10 | Mayo Foundation for Medical Education and Research | Treating cancer |
| EP2334785B2 (en) | 2008-09-16 | 2019-08-14 | Mayo Foundation For Medical Education And Research | Compositions containing platelet contents |
| WO2011053860A2 (en) * | 2009-10-30 | 2011-05-05 | Allocure, Inc. | Mesenchymal stromal cell populations and methods of using same |
| AU2010325546B2 (en) * | 2009-11-27 | 2014-10-16 | Stempeutics Research Pvt. Ltd. | Methods of preparing mesenchymal stem cells, compositions and kit thereof |
| ES2634545T3 (es) | 2010-06-01 | 2017-09-28 | Auxocell Laboratories, Inc. | Células madre nativas de la gelatina de Wharton y su purificación |
| WO2012048093A2 (en) | 2010-10-08 | 2012-04-12 | Osiris Therapeutics, Inc. | Enhanced msc preparations |
| HUE048876T2 (hu) | 2011-05-09 | 2020-08-28 | Mayo Found Medical Education & Res | Rákos megbetegedések kezelése |
| CN104508124B (zh) | 2011-07-06 | 2017-11-17 | 细胞治疗有限公司 | 中胚层谱系祖细胞 |
| US20130129688A1 (en) | 2011-11-09 | 2013-05-23 | Allocure, Inc. | Assay for the Prediction of Therapeutic Effectiveness or Potency of Mesenchymal Stem Cells, and Methods of Using Same |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| PL2785359T3 (pl) | 2011-11-30 | 2018-12-31 | Astellas Institute For Regenerative Medicine | Mezenchymalne komórki zrębowe i związane z nimi zastosowania |
| WO2013166026A1 (en) | 2012-04-30 | 2013-11-07 | Allocure, Inc. | Methods of treating acute kidney injury using mesenchymal stem cells |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| US10413606B2 (en) | 2012-10-01 | 2019-09-17 | Mayo Foundation For Medical Education And Research | Methods for treating cancer with nanoparticle complexes of albumin-bound paclitaxel and anti-VEGF antibodies |
| WO2014193895A1 (en) | 2013-05-29 | 2014-12-04 | Allocure, Inc. | Ex vivo perfusion of donor organs prior to transplantation using mesenchymal stem cells |
| EP3028052B1 (en) * | 2013-08-01 | 2017-11-01 | Fundación Pública Andaluza Progreso Y Salud | Method for predicting treatment response and test for safe use of mesenchymal stem cells on inflammatory diseases. |
| EP3143130B1 (en) | 2014-05-16 | 2024-03-06 | Mayo Foundation for Medical Education and Research | Cell culture media compositions for primary cells |
| EP3154586B1 (en) | 2014-06-13 | 2020-05-27 | Mayo Foundation for Medical Education and Research | Treating lymphomas |
| US10213513B2 (en) | 2014-06-16 | 2019-02-26 | Mayo Foundation For Medical Education And Research | Treating myelomas |
| CN107073132B (zh) | 2014-10-06 | 2021-08-27 | 梅约医学教育与研究基金会 | 载体-抗体组合物及其制备和使用方法 |
| TW201707725A (zh) | 2015-08-18 | 2017-03-01 | 美國馬友醫藥教育研究基金會 | 載體－抗體組合物及其製造及使用方法 |
| TW201713360A (en) | 2015-10-06 | 2017-04-16 | Mayo Foundation | Methods of treating cancer using compositions of antibodies and carrier proteins |
| WO2017120501A1 (en) | 2016-01-07 | 2017-07-13 | Mayo Foundation For Medical Education And Research | Methods of treating cancer with interferon |
| US11351254B2 (en) | 2016-02-12 | 2022-06-07 | Mayo Foundation For Medical Education And Research | Hematologic cancer treatments |
| WO2017165440A1 (en) | 2016-03-21 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods for reducing toxicity of a chemotherapeutic drug |
| EP3432928A4 (en) | 2016-03-21 | 2019-11-20 | Mayo Foundation for Medical Education and Research | PROCESS FOR IMPROVING THE THERAPEUTIC INDEX FOR CHEMOTHERAPEUTIC |
| US10618969B2 (en) | 2016-04-06 | 2020-04-14 | Mayo Foundation For Medical Education And Research | Carrier-binding agent compositions and methods of making and using the same |
| CN109843336A (zh) | 2016-09-01 | 2019-06-04 | 梅约医学教育与研究基金会 | 用于靶向t细胞癌症的方法和组合物 |
| CN109890419A (zh) | 2016-09-01 | 2019-06-14 | 梅约医学教育与研究基金会 | 用于治疗癌症的载体-pd-l1结合剂组合物 |
| AU2017324947A1 (en) | 2016-09-06 | 2019-03-28 | Mayo Foundation For Medical Education And Research | Paclitaxel-albumin-binding agent compositions and methods for using and making the same |
| CN109843924A (zh) | 2016-09-06 | 2019-06-04 | 梅约医学教育与研究基金会 | 治疗表达pd-l1的癌症的方法 |
| US11590098B2 (en) | 2016-09-06 | 2023-02-28 | Mayo Foundation For Medical Education And Research | Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins |
| US20190060365A1 (en) * | 2017-08-25 | 2019-02-28 | Meridigen Biotech Co., Ltd. | Pharmaceutical composition for treating chronic obstructive pulmonary disease and method thereof |
| WO2019102268A1 (en) | 2017-11-22 | 2019-05-31 | Mesoblast International Sarl | Cellular compositions and methods of treatment i |
| KR20220031555A (ko) | 2019-06-11 | 2022-03-11 | 옥소젠 코포레이션 | 조직의 습식 보존 |
| WO2021065971A1 (ja) * | 2019-09-30 | 2021-04-08 | テルモ株式会社 | 凍結保存細胞の希釈用緩衝液 |
| US20230270791A1 (en) * | 2020-07-31 | 2023-08-31 | Rainbow (Rainbow Inc.) | Platelet lysate derived from autologous platelets |
| US20250075184A1 (en) | 2021-03-30 | 2025-03-06 | Kaneka Corporation | Method for inhibiting trypsin, and method for producing a cell preparation using the same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE528214C2 (sv) * | 2005-06-23 | 2006-09-26 | Proliff Ab | Förfarande för framställning av blodplättslysat |
| US20090305401A1 (en) * | 2006-09-18 | 2009-12-10 | Dirk Strunk | Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics |
-
2009
- 2009-08-04 WO PCT/US2009/052733 patent/WO2010017216A2/en not_active Ceased
- 2009-08-04 US US13/057,698 patent/US20110293576A1/en not_active Abandoned
- 2009-08-04 AU AU2009279736A patent/AU2009279736A1/en not_active Abandoned
- 2009-08-04 CA CA2736353A patent/CA2736353A1/en not_active Abandoned
- 2009-08-04 EP EP09805454.7A patent/EP2321408A4/en not_active Withdrawn
- 2009-08-04 JP JP2011522168A patent/JP2011529706A/ja active Pending
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