JP2014508527A - 免疫調節活性を有する細胞集団、単離方法および使用 - Google Patents
免疫調節活性を有する細胞集団、単離方法および使用 Download PDFInfo
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- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1352—Mesenchymal stem cells
- C12N2502/1358—Bone marrow mesenchymal stem cells (BM-MSC)
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1352—Mesenchymal stem cells
- C12N2502/1382—Adipose-derived stem cells [ADSC], adipose stromal stem cells
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11157930.6 | 2011-03-11 | ||
| EP11157930 | 2011-03-11 | ||
| PCT/EP2012/054251 WO2012123401A1 (en) | 2011-03-11 | 2012-03-12 | Cell populations having immunoregulatory activity, method for isolation and uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014508527A true JP2014508527A (ja) | 2014-04-10 |
| JP2014508527A5 JP2014508527A5 (enExample) | 2015-04-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013557133A Pending JP2014508527A (ja) | 2011-03-11 | 2012-03-12 | 免疫調節活性を有する細胞集団、単離方法および使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140154227A1 (enExample) |
| EP (1) | EP2683813A1 (enExample) |
| JP (1) | JP2014508527A (enExample) |
| KR (1) | KR20140016933A (enExample) |
| ES (1) | ES2479565T1 (enExample) |
| WO (1) | WO2012123401A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| SG10202001007TA (en) | 2005-09-23 | 2020-03-30 | Tigenix Sau | Cell populations having immunoregulatory activity, method for isolation and uses |
| US20160120910A1 (en) * | 2013-06-25 | 2016-05-05 | Tigenix S.A.U. | Cell populations having immunoregulatory activity, methods for the preparation and uses thereof |
| EP3028052B1 (en) * | 2013-08-01 | 2017-11-01 | Fundación Pública Andaluza Progreso Y Salud | Method for predicting treatment response and test for safe use of mesenchymal stem cells on inflammatory diseases. |
| KR101931420B1 (ko) * | 2014-05-01 | 2018-12-20 | 가부시키가이샤 시마즈세이사쿠쇼 | 세포의 분화 상태의 평가 방법 |
| EP3160480B1 (en) * | 2014-06-30 | 2020-09-09 | TiGenix, S.A.U. | Mesenchymal stromal cells for treating rheumatoid arthritis |
| GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| CN110592002B (zh) * | 2019-10-10 | 2021-04-02 | 山东大学齐鲁医院 | 一种用于单细胞测序的膀胱尿路上皮单细胞悬液的制备方法及应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005056777A1 (ja) * | 2003-12-10 | 2005-06-23 | Hitachi Medical Corporation | 接着性幹細胞分画並びにその分離方法、品質管理方法及び品質管理装置 |
| JP2007536915A (ja) * | 2004-05-12 | 2007-12-20 | ザ ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ | 細胞単離方法 |
| JP2009508507A (ja) * | 2005-09-23 | 2009-03-05 | セリェリクス、ソシエダッド、リミターダ | 免疫調節活性を有する細胞集団、単離方法および使用 |
| WO2010052313A1 (en) * | 2008-11-07 | 2010-05-14 | Cellerix S.A. | Cells, nucleic acid constructs, cells comprising said constructs and methods utilizing said cells in the treatment of diseases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060045872A1 (en) * | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
-
2012
- 2012-03-12 KR KR1020137026776A patent/KR20140016933A/ko not_active Withdrawn
- 2012-03-12 ES ES12708032.3T patent/ES2479565T1/es active Pending
- 2012-03-12 JP JP2013557133A patent/JP2014508527A/ja active Pending
- 2012-03-12 WO PCT/EP2012/054251 patent/WO2012123401A1/en not_active Ceased
- 2012-03-12 EP EP12708032.3A patent/EP2683813A1/en not_active Withdrawn
- 2012-03-12 US US14/004,004 patent/US20140154227A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005056777A1 (ja) * | 2003-12-10 | 2005-06-23 | Hitachi Medical Corporation | 接着性幹細胞分画並びにその分離方法、品質管理方法及び品質管理装置 |
| JP2007536915A (ja) * | 2004-05-12 | 2007-12-20 | ザ ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ | 細胞単離方法 |
| JP2009508507A (ja) * | 2005-09-23 | 2009-03-05 | セリェリクス、ソシエダッド、リミターダ | 免疫調節活性を有する細胞集団、単離方法および使用 |
| WO2010052313A1 (en) * | 2008-11-07 | 2010-05-14 | Cellerix S.A. | Cells, nucleic acid constructs, cells comprising said constructs and methods utilizing said cells in the treatment of diseases |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2683813A1 (en) | 2014-01-15 |
| US20140154227A1 (en) | 2014-06-05 |
| ES2479565T1 (es) | 2014-08-20 |
| KR20140016933A (ko) | 2014-02-10 |
| WO2012123401A1 (en) | 2012-09-20 |
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