JP2020514299A5 - - Google Patents
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- Publication number
- JP2020514299A5 JP2020514299A5 JP2019536976A JP2019536976A JP2020514299A5 JP 2020514299 A5 JP2020514299 A5 JP 2020514299A5 JP 2019536976 A JP2019536976 A JP 2019536976A JP 2019536976 A JP2019536976 A JP 2019536976A JP 2020514299 A5 JP2020514299 A5 JP 2020514299A5
- Authority
- JP
- Japan
- Prior art keywords
- chemical formula
- solvate
- hydrate
- structure represented
- following chemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 CC(C)C*C(*)(*)SSC*(*)C*CN(*)CIC(CON)CON Chemical compound CC(C)C*C(*)(*)SSC*(*)C*CN(*)CIC(CON)CON 0.000 description 3
- ANZUADGNOKSXOB-UHFFFAOYSA-N CCOc1ccc(C(CC2)C(CC3)C(CC4)C2(C)C4OCCCOC(C(F)(F)F)(C(F)(F)F)C(F)(F)F)c3c1 Chemical compound CCOc1ccc(C(CC2)C(CC3)C(CC4)C2(C)C4OCCCOC(C(F)(F)F)(C(F)(F)F)C(F)(F)F)c3c1 ANZUADGNOKSXOB-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762443822P | 2017-01-09 | 2017-01-09 | |
| US62/443,822 | 2017-01-09 | ||
| PCT/IL2018/050031 WO2018127927A1 (en) | 2017-01-09 | 2018-01-09 | Compounds and methods for trans-membrane delivery of molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020514299A JP2020514299A (ja) | 2020-05-21 |
| JP2020514299A5 true JP2020514299A5 (enExample) | 2021-02-18 |
| JP7348064B2 JP7348064B2 (ja) | 2023-09-20 |
Family
ID=62789169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019536976A Active JP7348064B2 (ja) | 2017-01-09 | 2018-01-09 | 分子を経膜送達するための化合物及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11230710B2 (enExample) |
| EP (1) | EP3565603B1 (enExample) |
| JP (1) | JP7348064B2 (enExample) |
| KR (1) | KR20190104392A (enExample) |
| CN (1) | CN110402152B (enExample) |
| AU (1) | AU2018205898B2 (enExample) |
| CA (1) | CA3049640A1 (enExample) |
| EA (1) | EA201991661A1 (enExample) |
| IL (1) | IL267919B2 (enExample) |
| WO (1) | WO2018127927A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11318206B2 (en) | 2014-03-28 | 2022-05-03 | Aposense Ltd | Compounds and methods for trans-membrane delivery of molecules |
| AU2018205898B2 (en) | 2017-01-09 | 2020-12-10 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| US10195286B2 (en) * | 2017-07-04 | 2019-02-05 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| JP7820060B2 (ja) * | 2018-01-01 | 2026-02-25 | アポセンス リミテッド | 分子の膜貫通送達のための化合物および方法 |
| WO2020044349A1 (en) * | 2018-08-30 | 2020-03-05 | Aposense Ltd. | Compounds, cojugates and compositions for use in the methods for trans-membrane delivery of molecules |
| WO2023022055A1 (ja) * | 2021-08-17 | 2023-02-23 | 国立大学法人東海国立大学機構 | 修飾ポリヌクレオチド |
| WO2025096244A1 (en) * | 2023-10-30 | 2025-05-08 | Olfera Corporation | Olfactory delivery scaffolds and methods for making and using same |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0935415B1 (en) | 1996-05-01 | 2006-11-22 | Imarx Pharmaceutical Corp. | In vitro methods for delivering nucleic acids into a cell |
| US6090800A (en) | 1997-05-06 | 2000-07-18 | Imarx Pharmaceutical Corp. | Lipid soluble steroid prodrugs |
| WO1998050041A1 (en) | 1997-05-06 | 1998-11-12 | Imarx Pharmaceutical Corp. | Novel prodrugs comprising fluorinated amphiphiles |
| FR2846969A1 (fr) | 2002-11-08 | 2004-05-14 | Salles Jean Pierre | Nouveaux vecteurs moleculaires amphiphiles fluorocarbones a usage biomedical et medical |
| SE527131C2 (sv) | 2004-02-13 | 2005-12-27 | Innoventus Project Ab | Steroider för cancerbehandling |
| ATE487692T1 (de) * | 2004-07-08 | 2010-11-15 | Aposense Ltd | Verfahren und verbindungen zum nachweis von medizinischen erkrankungen |
| KR20070053214A (ko) * | 2004-08-26 | 2007-05-23 | 니콜라스 피라말 인디아 리미티드 | 신규 생분해성 링커를 함유하는 프로드럭 |
| PT1804780E (pt) | 2004-10-01 | 2012-01-19 | Prometic Biosciences Inc | Álcoois gordos com comprimento médio da cadeia como estimuladores da hematopoiese |
| RU2408605C2 (ru) | 2005-02-18 | 2011-01-10 | Анджиокем Инк. | Полипептид, способный преодолевать гематоэнцефалический барьер, и его конъюгат |
| WO2008036841A2 (en) | 2006-09-22 | 2008-03-27 | Dharmacon, Inc. | Tripartite oligonucleotide complexes and methods for gene silencing by rna interference |
| CA2910760C (en) | 2007-12-04 | 2019-07-09 | Muthiah Manoharan | Targeting lipids |
| CA2724105C (en) | 2008-05-13 | 2017-09-05 | University Of Washington | Diblock copolymers and polynucleotide complexes thereof for delivery into cells |
| WO2009155335A2 (en) | 2008-06-19 | 2009-12-23 | University Of Maryland, Baltimore | Conjugates of 19f mr imaging tracers and chemotherapeutic agents for drug quantification and drug dose individualization |
| US8796443B2 (en) | 2008-09-22 | 2014-08-05 | Rxi Pharmaceuticals Corporation | Reduced size self-delivering RNAi compounds |
| US20120035362A1 (en) | 2010-08-03 | 2012-02-09 | Berry And Associates, Inc. | Phosphoramidite derivatives of folic acid |
| GB201122458D0 (en) | 2011-12-30 | 2012-02-08 | Univ Wageningen | Modified cascade ribonucleoproteins and uses thereof |
| PL4289948T3 (pl) | 2012-05-25 | 2025-06-02 | The Regents Of The University Of California | Sposoby i kompozycje do modyfikacji kierowanego na rna docelowego dna i do nakierowanej na rna modulacji transkrypcji |
| JP2015523860A (ja) | 2012-05-30 | 2015-08-20 | ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ | ＤＮＡの修復、変更および置き換えのための道具としてのスーパーコイルＭｉｎｉＶｅｃｔｏｒ |
| AU2013331440A1 (en) * | 2012-10-16 | 2015-04-30 | Endocyte, Inc. | Drug delivery conjugates containing unnatural amino acids and methods for using |
| WO2014127052A1 (en) | 2013-02-13 | 2014-08-21 | Zondlo Neal | Perfluoro-tert-butyl hydroxyproline |
| US9593077B2 (en) | 2013-11-18 | 2017-03-14 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
| US9889202B2 (en) | 2014-03-28 | 2018-02-13 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| US9993563B2 (en) | 2014-03-28 | 2018-06-12 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| JP6669719B2 (ja) | 2014-03-28 | 2020-03-18 | アポセンス リミテッドＡｐｏｓｅｎｓｅ Ｌｔｄ． | 分子の膜貫通送達のための化合物および方法 |
| US20160016855A1 (en) * | 2014-07-21 | 2016-01-21 | Benxin Wu | Fabrication of carbon nanotube-nonoxide structural ceramic nanocomposites through laser sintering |
| AU2018205898B2 (en) | 2017-01-09 | 2020-12-10 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
| US10195286B2 (en) | 2017-07-04 | 2019-02-05 | Aposense Ltd. | Compounds and methods for trans-membrane delivery of molecules |
-
2018
- 2018-01-09 AU AU2018205898A patent/AU2018205898B2/en active Active
- 2018-01-09 CN CN201880017053.0A patent/CN110402152B/zh active Active
- 2018-01-09 CA CA3049640A patent/CA3049640A1/en active Pending
- 2018-01-09 IL IL267919A patent/IL267919B2/en unknown
- 2018-01-09 EP EP18736287.6A patent/EP3565603B1/en active Active
- 2018-01-09 JP JP2019536976A patent/JP7348064B2/ja active Active
- 2018-01-09 KR KR1020197023505A patent/KR20190104392A/ko not_active Withdrawn
- 2018-01-09 US US16/476,557 patent/US11230710B2/en active Active
- 2018-01-09 WO PCT/IL2018/050031 patent/WO2018127927A1/en not_active Ceased
- 2018-01-09 EA EA201991661A patent/EA201991661A1/ru unknown