JP2020512385A5 - - Google Patents
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- Publication number
- JP2020512385A5 JP2020512385A5 JP2019553971A JP2019553971A JP2020512385A5 JP 2020512385 A5 JP2020512385 A5 JP 2020512385A5 JP 2019553971 A JP2019553971 A JP 2019553971A JP 2019553971 A JP2019553971 A JP 2019553971A JP 2020512385 A5 JP2020512385 A5 JP 2020512385A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- immunoamphiphile
- immune
- fusion protein
- binding peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091006020 Fc-tagged proteins Proteins 0.000 claims 6
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 239000000835 fiber Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- OGQYPPBGSLZBEG-UHFFFAOYSA-N dimethyl(dioctadecyl)azanium Chemical compound CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC OGQYPPBGSLZBEG-UHFFFAOYSA-N 0.000 claims 2
- 239000007850 fluorescent dye Substances 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 101000582398 Staphylococcus aureus Replication initiation protein Proteins 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- 238000010828 elution Methods 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 238000001471 micro-filtration Methods 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical group [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 claims 1
- 229940043267 rhodamine b Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022168138A JP2023011689A (ja) | 2017-03-30 | 2022-10-20 | 生体高分子の精製のための超分子高アフィニティタンパク質結合系 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762478886P | 2017-03-30 | 2017-03-30 | |
| US62/478,886 | 2017-03-30 | ||
| PCT/US2018/024721 WO2018183417A1 (en) | 2017-03-30 | 2018-03-28 | A supramolecular high affinity protein-binding system for purification of biomacromolecules |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022168138A Division JP2023011689A (ja) | 2017-03-30 | 2022-10-20 | 生体高分子の精製のための超分子高アフィニティタンパク質結合系 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020512385A JP2020512385A (ja) | 2020-04-23 |
| JP2020512385A5 true JP2020512385A5 (https=) | 2021-05-06 |
| JP7229169B2 JP7229169B2 (ja) | 2023-02-27 |
Family
ID=63678187
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019553971A Active JP7229169B2 (ja) | 2017-03-30 | 2018-03-28 | 生体高分子の精製のための超分子高アフィニティタンパク質結合系 |
| JP2022168138A Pending JP2023011689A (ja) | 2017-03-30 | 2022-10-20 | 生体高分子の精製のための超分子高アフィニティタンパク質結合系 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022168138A Pending JP2023011689A (ja) | 2017-03-30 | 2022-10-20 | 生体高分子の精製のための超分子高アフィニティタンパク質結合系 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US11359005B2 (https=) |
| EP (1) | EP3601362A4 (https=) |
| JP (2) | JP7229169B2 (https=) |
| KR (2) | KR102660861B1 (https=) |
| CN (2) | CN110741017B (https=) |
| WO (1) | WO2018183417A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3601362A4 (en) * | 2017-03-30 | 2020-12-16 | The Johns Hopkins University | HIGH AFFINITY PROTEIN SUPRAMOLECULAR BINDING SYSTEM FOR BIOMACROMOLECULES PURIFICATION |
| JP7379323B2 (ja) * | 2017-08-18 | 2023-11-14 | ザ・ジョンズ・ホプキンス・ユニバーシティ | タンパク質精製のための超分子フィラメント集合体 |
| US20210130395A1 (en) * | 2018-05-11 | 2021-05-06 | William Marsh Rice University | Proximity induced site-specific antibody conjugation |
| CN114225020B (zh) * | 2021-12-31 | 2023-05-02 | 暨南大学 | 一种ova淀粉样蛋白原纤维及其制备方法与应用 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5476996A (en) | 1988-06-14 | 1995-12-19 | Lidak Pharmaceuticals | Human immune system in non-human animal |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| EP1690934A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
| US6300129B1 (en) | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| US6255458B1 (en) | 1990-08-29 | 2001-07-03 | Genpharm International | High affinity human antibodies and human antibodies against digoxin |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| ES2341666T3 (es) | 1991-12-02 | 2010-06-24 | Medimmune Limited | Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos. |
| CA2124967C (en) | 1991-12-17 | 2008-04-08 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| CA2161351C (en) | 1993-04-26 | 2010-12-21 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| US6013763A (en) * | 1996-06-04 | 2000-01-11 | Genentech, Inc. | Peptide variants of protein A |
| IL148079A0 (en) | 1999-08-24 | 2002-09-12 | Medarex Inc | Human ctla-4 antibodies and compositions containing the same |
| CN1487996B (zh) | 2000-11-30 | 2010-06-16 | 米德列斯公司 | 用于生产人类抗体的转基因转染色体啮齿动物 |
| WO2006123829A1 (ja) * | 2005-05-17 | 2006-11-23 | Sapporo Medical University | ＰＡＰ２ａに対する抗体ならびにその診断的および治療的使用 |
| US8551781B2 (en) * | 2009-11-19 | 2013-10-08 | The Regents Of The University Of California | Vault complexes for facilitating biomolecule delivery |
| EP3601362A4 (en) * | 2017-03-30 | 2020-12-16 | The Johns Hopkins University | HIGH AFFINITY PROTEIN SUPRAMOLECULAR BINDING SYSTEM FOR BIOMACROMOLECULES PURIFICATION |
| JP7379323B2 (ja) * | 2017-08-18 | 2023-11-14 | ザ・ジョンズ・ホプキンス・ユニバーシティ | タンパク質精製のための超分子フィラメント集合体 |
-
2018
- 2018-03-28 EP EP18775537.6A patent/EP3601362A4/en active Pending
- 2018-03-28 KR KR1020197031323A patent/KR102660861B1/ko active Active
- 2018-03-28 KR KR1020237034773A patent/KR20230148855A/ko not_active Ceased
- 2018-03-28 CN CN201880036846.7A patent/CN110741017B/zh active Active
- 2018-03-28 US US16/498,675 patent/US11359005B2/en active Active
- 2018-03-28 JP JP2019553971A patent/JP7229169B2/ja active Active
- 2018-03-28 WO PCT/US2018/024721 patent/WO2018183417A1/en not_active Ceased
- 2018-03-28 CN CN202311018377.5A patent/CN117024534A/zh active Pending
-
2022
- 2022-06-07 US US17/833,941 patent/US12466875B2/en active Active
- 2022-10-20 JP JP2022168138A patent/JP2023011689A/ja active Pending
-
2025
- 2025-10-31 US US19/375,762 patent/US20260049121A1/en active Pending
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