JP2020511454A5 - - Google Patents
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- Publication number
- JP2020511454A5 JP2020511454A5 JP2019549411A JP2019549411A JP2020511454A5 JP 2020511454 A5 JP2020511454 A5 JP 2020511454A5 JP 2019549411 A JP2019549411 A JP 2019549411A JP 2019549411 A JP2019549411 A JP 2019549411A JP 2020511454 A5 JP2020511454 A5 JP 2020511454A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- pharmaceutically acceptable
- acceptable salt
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 *c1cc(NC(Nc2c(*)c(cccc3)c3nc2)=O)cnc1-[n]1nccn1 Chemical compound *c1cc(NC(Nc2c(*)c(cccc3)c3nc2)=O)cnc1-[n]1nccn1 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762468758P | 2017-03-08 | 2017-03-08 | |
| US62/468,758 | 2017-03-08 | ||
| US201762553336P | 2017-09-01 | 2017-09-01 | |
| US62/553,336 | 2017-09-01 | ||
| PCT/US2018/021481 WO2018165385A1 (en) | 2017-03-08 | 2018-03-08 | Inhibitors of malt1 and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020511454A JP2020511454A (ja) | 2020-04-16 |
| JP2020511454A5 true JP2020511454A5 (https=) | 2021-04-15 |
| JP7142022B2 JP7142022B2 (ja) | 2022-09-26 |
Family
ID=63448912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019549411A Active JP7142022B2 (ja) | 2017-03-08 | 2018-03-08 | Ｍａｌｔ１の阻害剤およびそれらの使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US11248007B2 (https=) |
| EP (1) | EP3592731A4 (https=) |
| JP (1) | JP7142022B2 (https=) |
| WO (1) | WO2018165385A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3490995A1 (en) * | 2016-07-29 | 2019-06-05 | Lupin Limited | Substituted thiazolo-pyridine compounds as malt1 inhibitors |
| PE20190656A1 (es) * | 2016-07-29 | 2019-05-08 | Lupin Ltd | Compuestos de tiazolo-piridina sustituida como inhibidores de malt1 |
| TWI795381B (zh) | 2016-12-21 | 2023-03-11 | 比利時商健生藥品公司 | 作為ｍａｌｔ１抑制劑之吡唑衍生物 |
| TWI848400B (zh) | 2018-11-28 | 2024-07-11 | 日商武田藥品工業股份有限公司 | 雜環化合物及醫藥 |
| US20200292543A1 (en) * | 2019-03-12 | 2020-09-17 | Quidel Corporation | Compositions, kits, and methods for detecting autoantibodies |
| EP3953345B1 (en) * | 2019-04-11 | 2023-04-05 | Janssen Pharmaceutica NV | Pyridine rings containing derivatives as malt1 inhibitors |
| WO2021000855A1 (en) * | 2019-07-01 | 2021-01-07 | Qilu Regor Therapeutics Inc. | Malt1 inhibitors and uses thereof |
| WO2021241611A1 (ja) * | 2020-05-27 | 2021-12-02 | 武田薬品工業株式会社 | 複素環化合物の製造方法 |
| WO2022101676A1 (en) * | 2020-11-12 | 2022-05-19 | Monopteros Therapeutics,Inc. | Materials and methods of treating cancer |
| CN118451068A (zh) | 2021-12-30 | 2024-08-06 | 上海翰森生物医药科技有限公司 | 三并环类衍生物抑制剂、其制备方法和应用 |
| EP4680232A2 (en) * | 2023-03-17 | 2026-01-21 | The Trustees of The University of Pennsylvania | Combinations of retinaldehyde dehydrogenase 1 (raldh1) inhibitors and immunostimulators and methods using same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5596001A (en) | 1993-10-25 | 1997-01-21 | Pfizer Inc. | 4-aryl-3-(heteroarylureido)quinoline derivatves |
| US9090592B2 (en) * | 2010-12-30 | 2015-07-28 | AbbVie Deutschland GmbH & Co. KG | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors |
| GB2504550A (en) | 2012-08-03 | 2014-02-05 | Nanyang Polytechnic | Diarylurea compound PQ401 for inhibiting the growth and/or proliferation of cancer stem cells |
| EA201590916A1 (ru) | 2012-11-09 | 2016-02-29 | Корнэлл Юниверсити | Низкомолекулярные ингибиторы malt1 |
| WO2014086478A1 (en) * | 2012-12-03 | 2014-06-12 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Inhibitors of malt1 protease |
| SG11201607895PA (en) * | 2014-05-28 | 2016-12-29 | Novartis Ag | Novel pyrazolo pyrimidine derivatives and their use as malt1 inhibitors |
| PE20190656A1 (es) | 2016-07-29 | 2019-05-08 | Lupin Ltd | Compuestos de tiazolo-piridina sustituida como inhibidores de malt1 |
| US10689366B2 (en) | 2016-11-01 | 2020-06-23 | Cornell University | Compounds for MALT1 degredation |
-
2018
- 2018-03-08 WO PCT/US2018/021481 patent/WO2018165385A1/en not_active Ceased
- 2018-03-08 EP EP18763780.6A patent/EP3592731A4/en not_active Withdrawn
- 2018-03-08 JP JP2019549411A patent/JP7142022B2/ja active Active
- 2018-03-08 US US16/492,066 patent/US11248007B2/en active Active
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