JP2020510059A5 - - Google Patents
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- JP2020510059A5 JP2020510059A5 JP2019550235A JP2019550235A JP2020510059A5 JP 2020510059 A5 JP2020510059 A5 JP 2020510059A5 JP 2019550235 A JP2019550235 A JP 2019550235A JP 2019550235 A JP2019550235 A JP 2019550235A JP 2020510059 A5 JP2020510059 A5 JP 2020510059A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- alkoxy
- alkyl
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(NCc1cnc(*)[s]1)=S Chemical compound *C(NCc1cnc(*)[s]1)=S 0.000 description 2
- KUGMNPKVESLWCR-UHFFFAOYSA-N C/[O]=S(\c1c2cccc1)/c(ccc(C(O)=O)c1)c1NC2=O Chemical compound C/[O]=S(\c1c2cccc1)/c(ccc(C(O)=O)c1)c1NC2=O KUGMNPKVESLWCR-UHFFFAOYSA-N 0.000 description 2
- MAQWCDYCXJXWQU-UHFFFAOYSA-N COC(c(cc1)cc([N+]([O-])=O)c1Sc(cccc1)c1C(OC)=O)=O Chemical compound COC(c(cc1)cc([N+]([O-])=O)c1Sc(cccc1)c1C(OC)=O)=O MAQWCDYCXJXWQU-UHFFFAOYSA-N 0.000 description 1
- UWIFKJLMIUEHQC-UHFFFAOYSA-N NCc1cnc(C(F)(F)F)[s]1 Chemical compound NCc1cnc(C(F)(F)F)[s]1 UWIFKJLMIUEHQC-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762470560P | 2017-03-13 | 2017-03-13 | |
| US62/470,560 | 2017-03-13 | ||
| PCT/US2018/022100 WO2018169907A1 (en) | 2017-03-13 | 2018-03-13 | Process for making hepatitis b core protein modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020510059A JP2020510059A (ja) | 2020-04-02 |
| JP2020510059A5 true JP2020510059A5 (https=) | 2021-04-15 |
| JP7179751B2 JP7179751B2 (ja) | 2022-11-29 |
Family
ID=61768549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019550235A Active JP7179751B2 (ja) | 2017-03-13 | 2018-03-13 | Ｂ型肝炎コアタンパク質モジュレーターを作製する方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11040965B2 (https=) |
| EP (1) | EP3596070A1 (https=) |
| JP (1) | JP7179751B2 (https=) |
| KR (1) | KR102575605B1 (https=) |
| CN (1) | CN110612300B (https=) |
| AU (1) | AU2018236188B2 (https=) |
| CA (1) | CA3056696A1 (https=) |
| SG (1) | SG11201908475RA (https=) |
| WO (1) | WO2018169907A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017326356A1 (en) | 2016-09-15 | 2019-04-11 | Assembly Biosciences, Inc. | Hepatitis B core protein modulators |
| CA3055194A1 (en) | 2017-03-02 | 2018-09-07 | Assembly Biosciences, Inc. | Cyclic sulfamide compounds and methods of using same |
| BR112021023622A2 (pt) * | 2019-05-24 | 2022-04-19 | Assembly Biosciences Inc | Composições farmaceuticas para o tratamento de hbv |
| CN111333513B (zh) * | 2020-04-17 | 2021-08-27 | 江苏恒沛药物科技有限公司 | 一种2,4-二氟-3-硝基苯甲酸的制备方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1480553A (en) | 1976-06-03 | 1977-07-20 | Pfizer Ltd | Tricyclic sulphonamides |
| JPS58225074A (ja) | 1982-06-25 | 1983-12-27 | Chugai Pharmaceut Co Ltd | ジベンゾオキサゼピン誘導体 |
| GB9109557D0 (en) | 1991-05-02 | 1991-06-26 | Wellcome Found | Chemical compounds |
| US5512563A (en) | 1993-07-29 | 1996-04-30 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| GB9707695D0 (en) * | 1996-08-07 | 1997-06-04 | Hoffmann La Roche | Tricyclic dione derivatives |
| US20050192286A1 (en) * | 2003-10-22 | 2005-09-01 | Neurocrine Biosciences, Inc. | Ligands of melanocortin receptors and compositions and methods related thereto |
| DE102004004928A1 (de) | 2004-01-31 | 2005-08-18 | Bayer Healthcare Ag | Dibenzoxazepine II |
| WO2007047737A1 (en) | 2005-10-17 | 2007-04-26 | Acadia Pharmaceuticals Inc. | Cb-1 modulating compounds and their use |
| WO2007056388A2 (en) | 2005-11-07 | 2007-05-18 | The General Hospital Corporation | Compositions and methods for modulating poly (adp-ribose) polymerase activity |
| JP4042065B1 (ja) | 2006-03-10 | 2008-02-06 | 健治 吉田 | 情報処理装置への入力処理システム |
| US20100022509A1 (en) | 2006-06-07 | 2010-01-28 | Fahey Robert C | Inhibitors of MshC and Homologs Thereof, and Methods of Identifying Same |
| WO2008118141A2 (en) | 2006-10-17 | 2008-10-02 | Acadia Pharmaceuticals Inc. | Use of cannabinoid modulating compounds in combination with other therapeutic compounds for adjunctive therapy |
| AU2009274255A1 (en) | 2008-07-23 | 2010-01-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibitors of the plasmodial surface anion channel as antimalarials |
| WO2012045194A1 (en) | 2010-10-09 | 2012-04-12 | Abbott Laboratories | Benzodiazepinones as fak inhibitors for treatment of cancer |
| JP5977347B2 (ja) | 2011-07-01 | 2016-08-24 | バルーク エス．ブルームバーグ インスティテュート | Ｈｂｖ感染に対する抗ウイルス剤としてのスルファモイルベンズアミド誘導体 |
| US20150141384A1 (en) * | 2012-07-03 | 2015-05-21 | Mahesh Kandula | Compositions and methods for the treatment of neurological degenerative disorders |
| RU2519546C1 (ru) | 2013-01-16 | 2014-06-10 | Общество С Ограниченной Ответственностью "Биоинтегратор" (Ооо "Биоинтегратор") | КОНЪЮГАТЫ И МАЛЫЕ МОЛЕКУЛЫ, ВЗАИМОДЕЙСТВУЮЩИЕ С РЕЦЕПТОРОМ CD16а |
| AR095426A1 (es) | 2013-03-14 | 2015-10-14 | Onyx Therapeutics Inc | Inhibidores tripeptídicos de la epoxicetona proteasa |
| EP3943087A1 (en) | 2013-03-15 | 2022-01-26 | Celgene CAR LLC | Heteroaryl compounds and uses thereof |
| EA031077B1 (ru) | 2013-06-19 | 2018-11-30 | Серагон Фармасьютикалз, Инк. | Модулятор рецептора эстрогена и его применения |
| US9550742B2 (en) * | 2013-07-29 | 2017-01-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | 11-OXO-10,11-dihydrodibenzo[B,F][1,4]thiazepine S-oxide derivatives and their use as dopamine D2 receptor antagonists |
| CN104803880B (zh) * | 2014-01-23 | 2017-11-21 | 广州喜鹊医药有限公司 | 一种具有神经保护作用的化合物及其制备方法和应用 |
| ES2748029T3 (es) | 2014-03-13 | 2020-03-12 | Univ Indiana Res & Tech Corp | Moduladores alostéricos de proteína núcleo de hepatitis B |
| PL3154949T3 (pl) | 2014-06-10 | 2018-08-31 | Basf Se | PODSTAWIONE ZWIĄZKI [1,2,4]TRIAZOLOWE i IMIDAZOLOWE JAKO FUNGICYDY |
| TWI721016B (zh) * | 2015-09-15 | 2021-03-11 | 美商艾森伯利生物科學公司 | B型肝炎核心蛋白質調節劑 |
| AU2017326356A1 (en) * | 2016-09-15 | 2019-04-11 | Assembly Biosciences, Inc. | Hepatitis B core protein modulators |
-
2018
- 2018-03-13 AU AU2018236188A patent/AU2018236188B2/en not_active Ceased
- 2018-03-13 CA CA3056696A patent/CA3056696A1/en active Pending
- 2018-03-13 EP EP18713555.3A patent/EP3596070A1/en not_active Withdrawn
- 2018-03-13 SG SG11201908475R patent/SG11201908475RA/en unknown
- 2018-03-13 KR KR1020197029525A patent/KR102575605B1/ko active Active
- 2018-03-13 WO PCT/US2018/022100 patent/WO2018169907A1/en not_active Ceased
- 2018-03-13 JP JP2019550235A patent/JP7179751B2/ja active Active
- 2018-03-13 US US16/493,614 patent/US11040965B2/en not_active Expired - Fee Related
- 2018-03-13 CN CN201880030078.4A patent/CN110612300B/zh not_active Expired - Fee Related
-
2021
- 2021-01-14 US US17/149,485 patent/US20210380577A1/en not_active Abandoned
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