JP2020509755A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020509755A5 JP2020509755A5 JP2019548956A JP2019548956A JP2020509755A5 JP 2020509755 A5 JP2020509755 A5 JP 2020509755A5 JP 2019548956 A JP2019548956 A JP 2019548956A JP 2019548956 A JP2019548956 A JP 2019548956A JP 2020509755 A5 JP2020509755 A5 JP 2020509755A5
- Authority
- JP
- Japan
- Prior art keywords
- host cell
- recombinant
- recombinant host
- seq
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022034241A JP2022078220A (ja) | 2017-03-10 | 2022-03-07 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
| JP2024024860A JP2024045697A (ja) | 2017-03-10 | 2024-02-21 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762470153P | 2017-03-10 | 2017-03-10 | |
| US62/470,153 | 2017-03-10 | ||
| PCT/US2018/021817 WO2018165594A1 (en) | 2017-03-10 | 2018-03-09 | Compositions and methods for producing high secreted yields of recombinant proteins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022034241A Division JP2022078220A (ja) | 2017-03-10 | 2022-03-07 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020509755A JP2020509755A (ja) | 2020-04-02 |
| JP2020509755A5 true JP2020509755A5 (enExample) | 2021-04-15 |
| JP7063486B2 JP7063486B2 (ja) | 2022-05-09 |
Family
ID=63448314
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019548956A Active JP7063486B2 (ja) | 2017-03-10 | 2018-03-09 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
| JP2022034241A Pending JP2022078220A (ja) | 2017-03-10 | 2022-03-07 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
| JP2024024860A Pending JP2024045697A (ja) | 2017-03-10 | 2024-02-21 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022034241A Pending JP2022078220A (ja) | 2017-03-10 | 2022-03-07 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
| JP2024024860A Pending JP2024045697A (ja) | 2017-03-10 | 2024-02-21 | 高分泌収量の組み換えタンパク質を産生するための組成物及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US10906947B2 (enExample) |
| EP (1) | EP3592762A4 (enExample) |
| JP (3) | JP7063486B2 (enExample) |
| KR (4) | KR20250121449A (enExample) |
| WO (1) | WO2018165594A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12351805B2 (en) | 2015-11-19 | 2025-07-08 | Northeastern University | Method of making recombinant silk and silk-amyloid hybrid proteins using bacteria |
| US11365225B2 (en) * | 2015-11-19 | 2022-06-21 | President And Fellows Of Harvard College | Method of making recombinant silk and silk-amyloid hybrid proteins using bacteria |
| KR20250121449A (ko) | 2017-03-10 | 2025-08-12 | 볼트 쓰레즈, 인크. | 재조합 단백질을 고분비 수율로 생산하기 위한 조성물 및 방법 |
| EP3592800A4 (en) | 2017-03-10 | 2021-01-06 | Bolt Threads, Inc. | COMPOSITIONS AND METHODS OF PRODUCING HIGHLY SECRETED YIELD OF RECOMBINANT PROTEIN |
| BR112022008699A2 (pt) * | 2019-11-27 | 2022-07-26 | Revelations Biotech Pvt Ltd | Ácidos nucleicos, vetores, células hospedeiras e métodos para a produção de frutosiltransferase a partir de aspergillus japonicus |
| CN117120618A (zh) | 2021-02-12 | 2023-11-24 | 勃林格殷格翰 Rcv 两合公司 | 用于增加蛋白质分泌的信号肽 |
| WO2023199285A2 (en) | 2022-04-15 | 2023-10-19 | Spora Spa | Mycotextiles including activated scaffolds and nano-particle cross-linkers and methods of making them |
| CA3257053A1 (en) | 2022-05-14 | 2023-11-23 | Novozymes A/S | COMPOSITIONS AND METHODS FOR THE PREVENTION, TREATMENT, SUPPRESSION AND/OR ELIMINATION OF PHYTOPATHOGENIC INFESTATIONS AND INFECTIONS |
| EP4642916A2 (en) | 2022-12-30 | 2025-11-05 | Biotalys NV | Secretion signals |
| US12467171B2 (en) | 2023-10-13 | 2025-11-11 | Spora Cayman Holdings Limited | Large-scale production of mycelium-based textiles at mushroom farm facilities |
| WO2026027251A1 (en) | 2024-08-01 | 2026-02-05 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Signal peptides for increased protein secretion |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6100042A (en) * | 1993-03-31 | 2000-08-08 | Cadus Pharmaceutical Corporation | Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor |
| US20030013154A1 (en) | 1998-02-24 | 2003-01-16 | Chiron Corporation | Pichia secretory leader for protein expression |
| WO2001077351A1 (en) | 2000-04-07 | 2001-10-18 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Vectors and methods for dual protein expression in pichia pastoris and escherichia coli |
| KR20030062854A (ko) | 2002-01-21 | 2003-07-28 | 주식회사 엘지생명과학 | 분비형 벡터를 이용한 효모에서의 재조합 단백질의 제조방법 |
| US7314974B2 (en) * | 2002-02-21 | 2008-01-01 | Monsanto Technology, Llc | Expression of microbial proteins in plants for production of plants with improved properties |
| CA2487907A1 (en) | 2002-06-11 | 2003-12-18 | Glaxosmithkline Biologicals S.A. | Immunogenic compositions comprising a xenogenic prostate protein p501s |
| WO2005070962A1 (en) * | 2004-01-21 | 2005-08-04 | Novozymes A/S | Production of a monoclonal antibody in a heterokaryon fungus or in a fungal host cell |
| US20070248967A1 (en) | 2005-06-09 | 2007-10-25 | National Institute Of Advanced Industrial Science | Reporter Assay Using Secrectory Luminescent Enzymes |
| KR20070009269A (ko) * | 2005-07-15 | 2007-01-18 | 한국생명공학연구원 | 재조합단백질 생산용 단백질융합인자 라이브러리 및이로부터 획득된 단백질융합인자 |
| JP5354559B2 (ja) * | 2005-11-24 | 2013-11-27 | 独立行政法人産業技術総合研究所 | 高効率分泌シグナルペプチド及びそれらを利用したタンパク質発現系 |
| WO2008052043A2 (en) * | 2006-10-24 | 2008-05-02 | Cogenesys, Inc. | Opioid receptor agonist fusion proteins |
| US20110165681A1 (en) | 2009-02-26 | 2011-07-07 | Massachusetts Institute Of Technology | Light-Activated Proton Pumps and Applications Thereof |
| US8501449B2 (en) * | 2007-12-04 | 2013-08-06 | Proteon Therapeutics, Inc. | Recombinant elastase proteins and methods of manufacturing and use thereof |
| WO2010058057A1 (es) | 2008-11-21 | 2010-05-27 | Consejo Superior De Investigaciones Científicas (Csic) (90%) | Lacasas de alto potencial redox obtenidas por evolución dirigida |
| US8440456B2 (en) * | 2009-05-22 | 2013-05-14 | Vib, Vzw | Nucleic acids of Pichia pastoris and use thereof for recombinant production of proteins |
| EP2258855A1 (en) * | 2009-05-28 | 2010-12-08 | Universität für Bodenkultur Wien | Expression sequences |
| US8785159B2 (en) * | 2009-11-25 | 2014-07-22 | Alliance For Sustainable Energy, Llc | Extracellular secretion of recombinant proteins |
| KR101291241B1 (ko) * | 2010-11-04 | 2013-08-01 | 한국생명공학연구원 | 효모에서 인체 상피세포 성장인자를 대량 생산하는 방법 |
| GB201105418D0 (en) | 2011-03-31 | 2011-05-18 | Univ Durham | Pesticide |
| EP2565262A1 (en) * | 2011-08-31 | 2013-03-06 | VTU Holding GmbH | Protein expression |
| US9732146B2 (en) | 2012-03-30 | 2017-08-15 | The United States Of America As Represented By The Department Of Veterans Affairs | Antibody-mediated transduction of heat shock proteins into living cells |
| US20150293076A1 (en) | 2012-10-22 | 2015-10-15 | Bolt Threads, Inc. | Cellular Reprogramming for Product Optimization |
| CN104837857B (zh) * | 2012-10-29 | 2018-11-06 | 龙沙有限公司 | 表达序列 |
| ES3057435T3 (en) * | 2013-03-15 | 2026-03-02 | H Lundbeck As | Temperature shift for high yield expression of polypeptides in yeast and other transformed cells |
| ES2887366T3 (es) * | 2013-09-17 | 2021-12-22 | Bolt Threads Inc | Métodos y composiciones para sintetizar fibras de seda mejoradas |
| CN114365792A (zh) | 2014-11-11 | 2022-04-19 | 克莱拉食品公司 | 用于生成卵清蛋白的方法和组合物 |
| CN114000218A (zh) | 2015-03-16 | 2022-02-01 | 保尔特纺织品公司 | 改善的丝纤维 |
| JP2018521239A (ja) | 2015-06-11 | 2018-08-02 | ボルト スレッズ インコーポレイテッド | 改善された特性を有する組換えタンパク質繊維糸 |
| BR112019002238A2 (pt) * | 2016-08-05 | 2019-05-14 | Cargill, Incorporated | polipeptídeo e célula manipulados, e, método de fermentação. |
| KR20250121449A (ko) | 2017-03-10 | 2025-08-12 | 볼트 쓰레즈, 인크. | 재조합 단백질을 고분비 수율로 생산하기 위한 조성물 및 방법 |
-
2018
- 2018-03-09 KR KR1020257025185A patent/KR20250121449A/ko active Pending
- 2018-03-09 KR KR1020237000420A patent/KR102618002B1/ko active Active
- 2018-03-09 JP JP2019548956A patent/JP7063486B2/ja active Active
- 2018-03-09 WO PCT/US2018/021817 patent/WO2018165594A1/en not_active Ceased
- 2018-03-09 EP EP18764964.5A patent/EP3592762A4/en active Pending
- 2018-03-09 KR KR1020237044072A patent/KR102840788B1/ko active Active
- 2018-03-09 KR KR1020197029638A patent/KR102486713B1/ko active Active
- 2018-03-13 US US15/920,331 patent/US10906947B2/en active Active
-
2020
- 2020-12-30 US US17/138,350 patent/US11370815B2/en active Active
-
2022
- 2022-03-07 JP JP2022034241A patent/JP2022078220A/ja active Pending
- 2022-05-23 US US17/751,277 patent/US12122810B2/en active Active
-
2024
- 2024-02-21 JP JP2024024860A patent/JP2024045697A/ja active Pending
- 2024-10-21 US US18/922,358 patent/US20250122252A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020509755A5 (enExample) | ||
| JP2020509751A5 (enExample) | ||
| CN116640205A (zh) | 重组xvii型胶原蛋白及其表达菌株 | |
| FI4011908T3 (fi) | Ultrapitkävaikutteiset insuliini-Fc-fuusioproteiinit ja niiden käyttömenetelmät | |
| CN110590939B (zh) | 一种利用基因工程获得重组人纤连蛋白的方法 | |
| US20240018563A1 (en) | Carbon-source regulated protein production in a recombinant host cell | |
| JP2019047804A5 (enExample) | ||
| JP2025024050A5 (enExample) | ||
| RU2015135980A (ru) | Клетки-хозяева и способы использования | |
| RU2015105330A (ru) | Укороченные варианты cd95-f-c | |
| JP2016514957A5 (enExample) | ||
| JP2799348B2 (ja) | 発現分泌ベクター | |
| CN118620065A (zh) | 重组人源化i型胶原蛋白及其表达载体和基因工程菌 | |
| CN102559739A (zh) | 重组人源lect2蛋白在毕赤酵母中的表达及纯化方法 | |
| CN119040163A (zh) | 一种可高效表达胶原蛋白的毕赤酵母工程菌及其构建方法 | |
| RU2009100910A (ru) | Промоторы с повышенной эффективностью транскрипции | |
| EP2225375A1 (en) | Improvement of the secretion yield of a protein of interest by in vivo proteolytic processing of a multimeric precursor | |
| JP2017524366A5 (enExample) | ||
| CN103966253A (zh) | 一种高效制备重组人白细胞介素-33蛋白的方法 | |
| US10655112B2 (en) | Polypeptide having endonuclease activity and method for producing the same | |
| CN118812702A (zh) | 具有止血性能的重组胶原蛋白及其制备方法和应用 | |
| RU2017118157A (ru) | Новая фитаза, способ ее получения и ее применение | |
| KR20140122603A (ko) | 세포외 피막성 백시니아 바이러스의 생성과 관련된 단백질을 코딩하는 폴리뉴클레오티드로 형질전환된 숙주세포 | |
| RU2014138583A (ru) | Способ уменьшения 1- сдвига рамки считывания | |
| JP2025017882A (ja) | ゼラチンの製造方法、添加剤および培地 |