JP2020507744A5 - - Google Patents

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JP2020507744A5
JP2020507744A5 JP2019533657A JP2019533657A JP2020507744A5 JP 2020507744 A5 JP2020507744 A5 JP 2020507744A5 JP 2019533657 A JP2019533657 A JP 2019533657A JP 2019533657 A JP2019533657 A JP 2019533657A JP 2020507744 A5 JP2020507744 A5 JP 2020507744A5
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light source
light
sample
detection vessel
angle
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JP2020507744A (ja
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Priority claimed from PCT/JP2017/045823 external-priority patent/WO2018117191A1/en
Publication of JP2020507744A publication Critical patent/JP2020507744A/ja
Publication of JP2020507744A5 publication Critical patent/JP2020507744A5/ja
Priority to JP2022140509A priority Critical patent/JP7425138B2/ja
Priority to JP2024005071A priority patent/JP7713044B2/ja
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JP2019533657A 2016-12-21 2017-12-20 デジタルアッセイのために横からの照射を使用した光学イメージングシステム Pending JP2020507744A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022140509A JP7425138B2 (ja) 2016-12-21 2022-09-05 デジタルアッセイのために横からの照射を使用した光学イメージングシステム
JP2024005071A JP7713044B2 (ja) 2016-12-21 2024-01-17 デジタルアッセイのために横からの照射を使用した光学イメージングシステム

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662437534P 2016-12-21 2016-12-21
US62/437,534 2016-12-21
PCT/JP2017/045823 WO2018117191A1 (en) 2016-12-21 2017-12-20 Optical imaging system using lateral illumination for digital assays

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JP2022140509A Division JP7425138B2 (ja) 2016-12-21 2022-09-05 デジタルアッセイのために横からの照射を使用した光学イメージングシステム

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JP2020507744A JP2020507744A (ja) 2020-03-12
JP2020507744A5 true JP2020507744A5 (https=) 2021-02-04

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JP2019533657A Pending JP2020507744A (ja) 2016-12-21 2017-12-20 デジタルアッセイのために横からの照射を使用した光学イメージングシステム
JP2022140509A Active JP7425138B2 (ja) 2016-12-21 2022-09-05 デジタルアッセイのために横からの照射を使用した光学イメージングシステム
JP2024005071A Active JP7713044B2 (ja) 2016-12-21 2024-01-17 デジタルアッセイのために横からの照射を使用した光学イメージングシステム

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JP2022140509A Active JP7425138B2 (ja) 2016-12-21 2022-09-05 デジタルアッセイのために横からの照射を使用した光学イメージングシステム
JP2024005071A Active JP7713044B2 (ja) 2016-12-21 2024-01-17 デジタルアッセイのために横からの照射を使用した光学イメージングシステム

Country Status (5)

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US (3) US10324041B2 (https=)
EP (1) EP3559640A4 (https=)
JP (3) JP2020507744A (https=)
CN (1) CN110366677A (https=)
WO (1) WO2018117191A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7785691B2 (ja) * 2020-04-29 2025-12-15 アボット・ラボラトリーズ 試料分析のためのシステム及び方法
WO2022202217A1 (ja) * 2021-03-26 2022-09-29 国立研究開発法人産業技術総合研究所 ウエルアレイを用いたウイルス検出方法、ウエルアレイ及び検出装置
JP7626121B2 (ja) 2022-10-27 2025-02-04 セイコーエプソン株式会社 投射方法、処理装置、プロジェクションシステム、及びプログラム
WO2025096384A1 (en) * 2023-10-31 2025-05-08 Board Of Regents For The Oklahoma Agricultural And Mechanical Colleges Colorimetric insulin immunosensor and methods of producing and using same
WO2025111479A1 (en) * 2023-11-21 2025-05-30 Abbott Laboratories Fluorogenic substrates and methods of use

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026159A (en) 1989-05-19 1991-06-25 Acrogen, Inc. Area-modulated luminescence (AML)
US5162990A (en) 1990-06-15 1992-11-10 The United States Of America As Represented By The United States Navy System and method for quantifying macrophage phagocytosis by computer image analysis
US5260578A (en) 1991-04-10 1993-11-09 Mayo Foundation For Medical Education And Research Confocal imaging system for visible and ultraviolet light
JP3324780B2 (ja) 1991-05-16 2002-09-17 オリンパス光学工業株式会社 紫外線顕微鏡
JP3326708B2 (ja) 1993-08-31 2002-09-24 日水製薬株式会社 光学的測定装置およびその方法
US5620850A (en) 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
US5880473A (en) 1997-07-28 1999-03-09 Applied Imaging, Inc. Multifluor-fluorescence in-situ hybridization (M-FISH) imaging techniques using multiple multiband filters with image registration
US6023540A (en) 1997-03-14 2000-02-08 Trustees Of Tufts College Fiber optic sensor with encoded microspheres
US6169816B1 (en) 1997-05-14 2001-01-02 Applied Imaging, Inc. Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images
US6259807B1 (en) 1997-05-14 2001-07-10 Applied Imaging Corp. Identification of objects of interest using multiple illumination schemes and finding overlap of features in corresponding multiple images
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
EP1067199A4 (en) 1998-12-28 2006-09-27 Sapporo Breweries METHOD FOR COUNTING MICROORGANISMS AND DEVICE FOR PERFORMING SAID COUNT
US6867851B2 (en) * 1999-11-04 2005-03-15 Regents Of The University Of Minnesota Scanning of biological samples
TWI335336B (https=) 2000-02-10 2011-01-01 Abbott Gmbh & Co Kg
US6759235B2 (en) * 2000-04-06 2004-07-06 Quantum Dot Corporation Two-dimensional spectral imaging system
US7175811B2 (en) * 2000-04-28 2007-02-13 Edgelight Biosciences Micro-array evanescent wave fluorescence detection device
WO2002068932A2 (en) * 2001-02-23 2002-09-06 Genicon Sciences Corporation Methods for providing extended dynamic range in analyte assays
US6960165B2 (en) * 2001-05-16 2005-11-01 Olympus Corporation Endoscope with a single image pick-up element for fluorescent and normal-light images
US7280207B2 (en) * 2001-07-25 2007-10-09 Applera Corporation Time-delay integration in a flow cytometry system
EP2311934B1 (en) * 2001-09-06 2013-06-05 Rapid Micro Biosystems, Inc. Rapid detection of replicating cells
EP1452866A1 (en) 2001-10-05 2004-09-01 BML, Inc. Sensing board
US7272252B2 (en) 2002-06-12 2007-09-18 Clarient, Inc. Automated system for combining bright field and fluorescent microscopy
US7050613B2 (en) 2002-11-07 2006-05-23 Fujitsu Limited Method for supporting cell image analysis
US7597936B2 (en) 2002-11-26 2009-10-06 University Of Utah Research Foundation Method of producing a pigmented composite microporous material
JP3727026B2 (ja) 2003-04-10 2005-12-14 博行 野地 一分子酵素活性検出に用いられるマイクロチャンバと1000fL以下の液滴を調製する方法
US7224468B2 (en) * 2003-10-20 2007-05-29 Agilent Technologies, Inc. En-face functional imaging using multiple wavelengths
JP2005147826A (ja) 2003-11-14 2005-06-09 Hamamatsu Photonics Kk 蛍光測定装置
JP4041458B2 (ja) * 2003-12-12 2008-01-30 日立ソフトウエアエンジニアリング株式会社 蛍光ビーズ検出方法及び蛍光ビーズ検出装置
EP1731941B1 (en) * 2004-03-31 2013-05-01 Olympus Corporation Observing device and fluorescent light observing device
JP4599941B2 (ja) 2004-08-20 2010-12-15 株式会社ニコン 自動焦点検出装置およびこれを備える顕微鏡システム
WO2006047038A1 (en) 2004-09-28 2006-05-04 Trustees Of Tufts College Apparatus and method for cell migration assays
JP2006098129A (ja) * 2004-09-28 2006-04-13 Aisin Seiki Co Ltd マイクロチャネルチップシステム及び検出チップ
US7602952B2 (en) 2004-11-16 2009-10-13 Illumina, Inc. Scanner having spatial light modulator
JP2006194730A (ja) 2005-01-13 2006-07-27 Moritex Corp エバネッセント波励起蛍光検出方法
JP4733433B2 (ja) * 2005-06-03 2011-07-27 株式会社日立ソリューションズ ビーズアレイ用蛍光読取装置及びビーズアレイ用蛍光読取方法
CN102622746B (zh) 2005-09-21 2016-05-25 卢米尼克斯股份有限公司 图像数据处理的方法和系统
US7749722B2 (en) 2005-12-15 2010-07-06 Mitsubishi Kagaku Istron, Inc. Measuring method using whole blood
WO2007076023A2 (en) * 2005-12-21 2007-07-05 Meso Scale Technologies, Llc Assay modules having assay reagents and methods of making and using same
US8492098B2 (en) 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
JP2009529681A (ja) * 2006-03-09 2009-08-20 テッサラエ、リミテッド、ライアビリティー、カンパニー マイクロアレイ撮像システムおよび関連した方法
US7838250B1 (en) 2006-04-04 2010-11-23 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
US8296088B2 (en) * 2006-06-02 2012-10-23 Luminex Corporation Systems and methods for performing measurements of one or more materials
US7764361B2 (en) * 2006-07-27 2010-07-27 Northwestern University Systems and methods to analyze multiplexed bead-based assays using backscattered light
JP5074044B2 (ja) * 2007-01-18 2012-11-14 オリンパス株式会社 蛍光観察装置および蛍光観察装置の作動方法
WO2008089495A2 (en) * 2007-01-19 2008-07-24 Purdue Research Foundation System with extended range of molecular sensing through integrated multi-modal data acquisition
US7700928B2 (en) * 2007-01-25 2010-04-20 Etaluma, Inc. Apparatus and method for interleaving detection of fluorescence and luminescence
US20080240543A1 (en) 2007-03-30 2008-10-02 Wolfgang Ernst Gustav Budach Calibration and normalization method for biosensors
EP1978363B1 (en) 2007-04-03 2010-02-24 Sysmex Corporation Immunoassay method, reagent kit for detecting alkaline phosphatase, and reagent kit for immunoassay
US8013991B2 (en) * 2007-08-08 2011-09-06 Chemimage Corporation Raman difference spectra based disease classification
US20120078524A1 (en) * 2007-08-08 2012-03-29 Chemlmage Corporation System and method for diagnosis tissue samples using fluorescence and raman techniques
WO2009029073A1 (en) 2007-08-30 2009-03-05 The Trustees Of Tufts College Methods for determining the concentration of an analyte in solution.
EP2208045B9 (en) * 2007-10-25 2012-01-04 Koninklijke Philips Electronics N.V. Sensor device for target particles in a sample
US20090137058A1 (en) * 2007-11-28 2009-05-28 General Electric Company Chemical and biological detection method and device based on measurements of fluorescence and reflectivity
US8791427B2 (en) 2007-12-26 2014-07-29 Olympus Corporation Biological-specimen observation apparatus
CN102165305B (zh) * 2008-09-25 2014-08-20 皇家飞利浦电子股份有限公司 检测系统与方法
DE102008054317A1 (de) 2008-11-03 2010-05-06 Carl Zeiss Microlmaging Gmbh Kombinationsmikroskopie
US8877028B2 (en) * 2009-04-21 2014-11-04 The University Of British Columbia System and methods for detection of particles
JP5338573B2 (ja) 2009-08-31 2013-11-13 ソニー株式会社 蛍光像取得方法、蛍光像取得装置及び蛍光像取得プログラム
JP5278252B2 (ja) 2009-08-31 2013-09-04 ソニー株式会社 組織切片像取得表示装置、組織切片像取得表示方法及び組織切片像取得表示プログラム
AU2010307140B2 (en) 2009-10-12 2014-05-15 Ventana Medical Systems, Inc. Multi-modality contrast and brightfield context rendering for enhanced pathology determination and multi-analyte detection in tissue
US8314377B2 (en) * 2009-12-23 2012-11-20 Mcneil-Ppc, Inc. Device and method for detecting plaque in the oral cavity
US8236574B2 (en) * 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
WO2011109379A1 (en) * 2010-03-01 2011-09-09 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
US9224031B2 (en) 2010-05-21 2015-12-29 Chemometec A/S Compact dark field light source and dark field image analysis at low magnification
CN103118785B (zh) * 2010-08-05 2015-11-25 雅培医护站股份有限公司 使用易感磁微珠捕获的免疫测定方法和装置
US11402375B2 (en) * 2010-08-05 2022-08-02 Abbott Point Of Care Inc. Magnetic immunosensor with trench configuration and method of use
DE102010044503B4 (de) * 2010-09-06 2017-11-02 Leica Microsystems (Schweiz) Ag Fluoreszenz-Operations-Stereomikroskop
WO2012051386A2 (en) * 2010-10-14 2012-04-19 Meso Scale Technologies, Llc Reagent storage in an assay device
US20120225475A1 (en) * 2010-11-16 2012-09-06 1087 Systems, Inc. Cytometry system with quantum cascade laser source, acoustic detector, and micro-fluidic cell handling system configured for inspection of individual cells
JP5644447B2 (ja) 2010-12-06 2014-12-24 ソニー株式会社 顕微鏡、領域判定方法、及びプログラム
US9952237B2 (en) 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
RU2548619C1 (ru) 2011-03-08 2015-04-20 Японское Агентство По Науке И Технике Способ герметизации гранул, способ обнаружения молекулы-мишени, матрица, набор и устройство для обнаружения молекулы-мишени
US8681215B2 (en) * 2011-04-29 2014-03-25 ProteinSimple Method and particle analyzer for determining a broad particle size distribution
CN103648649A (zh) * 2011-05-18 2014-03-19 3M创新有限公司 检测选定体积的材料在样本处理装置中存在的系统和方法
CN102243165B (zh) * 2011-06-20 2013-07-17 东南大学 光子晶体编码微球生物芯片检测装置
EP2882868B1 (en) * 2012-08-08 2019-07-31 H. Hoffnabb-La Roche Ag Increasing dynamic range for identifying multiple epitopes in cells
EP2883040A1 (en) * 2012-08-09 2015-06-17 Life Technologies Corporation Illumination systems
CN104870652A (zh) * 2012-10-05 2015-08-26 加州理工学院 用于微流体成像和分析的方法和系统
US9488579B2 (en) 2013-01-22 2016-11-08 Tecan Trading Ag Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US9488576B2 (en) 2013-01-22 2016-11-08 Tecan Trading Ag Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US8912007B2 (en) 2013-01-22 2014-12-16 Tecan Trading Ag Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US11366061B2 (en) * 2013-01-24 2022-06-21 Grace Bio-Labs, Inc. Protein microarray assay imager
KR101568573B1 (ko) * 2013-03-13 2015-11-20 고려대학교 산학협력단 혈중 희소 세포의 검출 및 계수 장치와 방법
WO2014176435A2 (en) * 2013-04-25 2014-10-30 Bergo Vladislav B Microarray compositions and methods of their use
KR101514204B1 (ko) * 2013-07-12 2015-04-23 한국전기연구원 감시림프절의 근적외선 형광 검출 장치 및 방법
JP6383370B2 (ja) * 2014-01-31 2018-08-29 オリンパス株式会社 蛍光観察装置
EP3101115B1 (en) 2014-01-31 2020-10-21 Toppan Printing Co., Ltd. Biomolecule analysis kit and biomolecule analysis method
FR3019900B1 (fr) 2014-04-09 2017-12-22 Bio-Rad Innovations Utilisation de particules absorbantes pour ameliorer la detection du signal dans un procede d'analyse
KR102437408B1 (ko) 2014-07-08 2022-08-29 고쿠리츠켄큐카이하츠호진 카가쿠기쥬츠신코키코 물질 봉입 방법 및 타깃 분자를 검출하는 방법
US9574989B2 (en) * 2014-08-08 2017-02-21 Omnivision Technologies, Inc. Lens-free imaging system and method for detecting particles in sample deposited on image sensor
CA2969078A1 (en) * 2014-11-28 2016-06-02 Chipcare Corporation Multiplex bead array assay
WO2016115537A2 (en) * 2015-01-15 2016-07-21 Massachusetts Institute Of Technology Systems, methods, and apparatus for in vitro single-cell identification and recovery
KR102494654B1 (ko) * 2015-02-06 2023-01-31 라이프 테크놀로지스 코포레이션 생물학적 시료 평가 시스템과 방법
SG11201706341RA (en) * 2015-02-06 2017-09-28 Life Technologies Corp Systems and methods for biological analysis
CN107735497B (zh) * 2015-02-18 2021-08-20 卓异生物公司 用于单分子检测的测定及其应用
CN107532333A (zh) * 2015-02-22 2018-01-02 里兰斯坦福初级大学理事会 微筛选装置、方法和产品
US9557270B2 (en) * 2015-03-04 2017-01-31 Ecolab Usa Inc. Multi-channel fluorometric sensor and method of using same
WO2016160844A2 (en) * 2015-03-30 2016-10-06 Cellular Research, Inc. Methods and compositions for combinatorial barcoding
JP6751970B2 (ja) * 2015-10-07 2020-09-16 セルマ・ダイアグノスティクス・アンパルトセルスカブSelma Diagnostics Aps デジタル計数のためのフローシステムおよび方法
US20170343476A1 (en) * 2016-05-31 2017-11-30 Molecular Devices, Llc Imaging system with oblique illumination
CN106226247A (zh) * 2016-07-15 2016-12-14 暨南大学 一种基于高光谱显微成像技术的细胞检测方法

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