JP2020507578A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020507578A5 JP2020507578A5 JP2019543277A JP2019543277A JP2020507578A5 JP 2020507578 A5 JP2020507578 A5 JP 2020507578A5 JP 2019543277 A JP2019543277 A JP 2019543277A JP 2019543277 A JP2019543277 A JP 2019543277A JP 2020507578 A5 JP2020507578 A5 JP 2020507578A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- chain variable
- variable domain
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710073984.XA CN108409863B (zh) | 2017-02-10 | 2017-02-10 | 抗凝血因子xi抗体 |
| CN201710073984.X | 2017-02-10 | ||
| PCT/CN2017/119856 WO2018145533A1 (zh) | 2017-02-10 | 2017-12-29 | 抗凝血因子xi抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020507578A JP2020507578A (ja) | 2020-03-12 |
| JP2020507578A5 true JP2020507578A5 (enExample) | 2021-02-12 |
| JP7271430B2 JP7271430B2 (ja) | 2023-05-11 |
Family
ID=63107934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019543277A Active JP7271430B2 (ja) | 2017-02-10 | 2017-12-29 | 抗ｘｉ因子抗体 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP3581587B1 (enExample) |
| JP (1) | JP7271430B2 (enExample) |
| KR (1) | KR102690437B1 (enExample) |
| CN (1) | CN108409863B (enExample) |
| AU (2) | AU2017397778B2 (enExample) |
| BR (1) | BR112019016300A2 (enExample) |
| CA (1) | CA3054322A1 (enExample) |
| MX (1) | MX2019009500A (enExample) |
| WO (1) | WO2018145533A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11958911B2 (en) | 2017-02-10 | 2024-04-16 | Shanghai Benemae Pharmaceutical | Anti-coagulation factor XI antibody |
| WO2020029179A1 (en) * | 2018-08-09 | 2020-02-13 | Shanghai Benemae Pharmaceutical Corporation | Anti-factor xi antibodies |
| CN110878123B (zh) | 2018-09-05 | 2022-08-23 | 华瑞同康生物技术（深圳）有限公司 | 一种抗tk1原核重组单链抗体及制备方法 |
| JP7509787B2 (ja) * | 2019-01-21 | 2024-07-02 | アロノラ・インコーポレイテッド | 抗血栓症作用および抗炎症作用を有する、第ｘｉ因子に対する新規ヒト化抗体およびその使用 |
| WO2020211674A1 (zh) * | 2019-04-16 | 2020-10-22 | 四川科伦博泰生物医药股份有限公司 | 抗FXI/FXIa抗体及其用途 |
| CN110423278B (zh) * | 2019-08-08 | 2020-07-17 | 上海博槿生物科技有限公司 | 一种抗凝血因子XI活化形式因子XIa的抗体及其制备方法和应用 |
| CN110498839A (zh) * | 2019-09-19 | 2019-11-26 | 河南省农业科学院 | 氟罗沙星单链抗体关键多肽序列及应用 |
| JP2023106635A (ja) | 2020-04-17 | 2023-08-02 | 中外製薬株式会社 | 二重特異性抗原結合分子ならびに、それに関連する組成物、組成物の製造のための使用、キット、および方法 |
| KR20230034361A (ko) * | 2020-07-02 | 2023-03-09 | 베이징 투오 지에 바이오파마수티컬 컴퍼니 리미티드 | 항-fxi/fxia 항체, 이의 항원-결합 단편, 및 이의 약제학적 용도 |
| CN116589588B (zh) * | 2023-04-14 | 2023-12-22 | 北京基科晟斯医药科技有限公司 | 结合凝血因子x的抗体 |
| WO2025130748A1 (zh) * | 2023-12-22 | 2025-06-26 | 四川科伦博泰生物医药股份有限公司 | 一种抗凝血因子XI/XIa抗体制剂 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2981754B2 (ja) * | 1990-02-02 | 1999-11-22 | 第一化学薬品株式会社 | 血液凝固第▲ｘ▼▲ｉｉｉ▼因子に対するモノクロナール抗体 |
| DE60230037D1 (de) * | 2001-06-12 | 2009-01-08 | Chemo Sero Therapeut Res Inst | Humanantikörper gegen blutgerinnungsfaktor viii |
| DE10205520A1 (de) * | 2002-02-08 | 2003-08-14 | Aventis Behring Gmbh | Inhibitorischer, monoklonaler Antikörper gegen die den Blutgerinnungsfaktor VII aktivierende Protease |
| ES2566963T3 (es) * | 2007-11-21 | 2016-04-18 | Oregon Health & Science University | Anticuerpos monoclonales anti-factor XI y métodos de uso de los mismos |
| LT2373691T (lt) * | 2008-12-18 | 2019-05-27 | Oregon Health & Science University | Anti-fxi antikūnai ir jų panaudojimo būdai |
| BR112014027952B1 (pt) * | 2012-05-10 | 2022-06-21 | Bayer Pharma Aktiengesellschaft | Anticorpos monoclonais humanos capazes de se ligarem ao fator de coagulação xi, seu uso, composição farmacêutica e medicamento os compreendendo, ácido nucleico que o codifica, bem como vetor |
| UY36751A (es) * | 2015-06-26 | 2017-01-31 | Novartis Ag | Anticuerpos de factor xi y métodos de uso |
| US11066481B2 (en) * | 2015-07-23 | 2021-07-20 | The Regents Of The University Of California | Antibodies to coagulation factor XIa and uses thereof |
-
2017
- 2017-02-10 CN CN201710073984.XA patent/CN108409863B/zh active Active
- 2017-12-29 CA CA3054322A patent/CA3054322A1/en active Pending
- 2017-12-29 JP JP2019543277A patent/JP7271430B2/ja active Active
- 2017-12-29 KR KR1020197025752A patent/KR102690437B1/ko active Active
- 2017-12-29 AU AU2017397778A patent/AU2017397778B2/en active Active
- 2017-12-29 MX MX2019009500A patent/MX2019009500A/es unknown
- 2017-12-29 BR BR112019016300-0A patent/BR112019016300A2/pt unknown
- 2017-12-29 EP EP17895532.4A patent/EP3581587B1/en active Active
- 2017-12-29 WO PCT/CN2017/119856 patent/WO2018145533A1/zh not_active Ceased
-
2025
- 2025-05-08 AU AU2025203303A patent/AU2025203303A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018524001A5 (enExample) | ||
| CY1120414T1 (el) | Αντισωματα που συνδεονται me οχ40 και οι χρησεις τους | |
| RU2014127287A (ru) | Антитела, используемые для пассивной вакцинации против гриппа | |
| RU2013140350A (ru) | Антитела против человеческого il33r и их применение | |
| EA201991577A1 (ru) | Новые антитела против рецептора трансферрина человека, способные преодолевать гематоэнцефалический барьер | |
| EA201791961A1 (ru) | Антитела, специфичные к cd47 и pd-l1 | |
| JP2020504101A5 (enExample) | ||
| FI3683235T3 (fi) | Anti-IL-33-vasta-aineita ja niiden käyttöjä | |
| EA201190132A1 (ru) | Гуманизированные антитела, связывающиеся с cd19, и их применение | |
| EA201990004A1 (ru) | АНТИ-IgE АНТИТЕЛА | |
| RU2018137110A (ru) | Антитела против psma и их применение | |
| EA202192907A1 (ru) | Моноклональное антитело, которое специфически связывается с gitr | |
| RU2018146533A (ru) | Антитела к cd40 и пути их применения | |
| PE20110801A1 (es) | Anticuerpos con reactividad cruzada y biespecificos anti-il-17a/f | |
| RU2016107814A (ru) | Новое антитело к tslp-рецептору человека | |
| EA201892522A1 (ru) | Днк-моноклональные антитела, нацеленные на молекулы контрольных точек | |
| PE20190261A1 (es) | Anticuerpos que reconocen tau | |
| AR105026A1 (es) | ANTICUERPOS MADURADOS POR AFINIDAD Y HUMANIZADOS PARA FcRH5 Y MÉTODOS PARA SU USO | |
| EA201790342A1 (ru) | Антитела к trem2 и способы их применения | |
| HRP20130877T1 (hr) | Antitijela koja neutraliziraju humani citomegalovirus i njihova primjena | |
| JP2021502984A5 (enExample) | ||
| MX388698B (es) | Moleculas de enlace, especialmente anticuerpos, enlazadas a l1cam(cd171). | |
| RU2010150105A (ru) | Гуманизированные антитела против альфа-интерферона человека | |
| RU2014145536A (ru) | Антитело против adamts-5, его производные и их применение | |
| PH12017500699A1 (en) | Antibodies that bind to ccr6 and their uses |