CN108409863B - 抗凝血因子xi抗体 - Google Patents
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- CN108409863B CN108409863B CN201710073984.XA CN201710073984A CN108409863B CN 108409863 B CN108409863 B CN 108409863B CN 201710073984 A CN201710073984 A CN 201710073984A CN 108409863 B CN108409863 B CN 108409863B
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Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710073984.XA CN108409863B (zh) | 2017-02-10 | 2017-02-10 | 抗凝血因子xi抗体 |
| RU2019128423A RU2800719C2 (ru) | 2017-02-10 | 2017-12-29 | Антитела к фактору xi |
| EP17895532.4A EP3581587B1 (en) | 2017-02-10 | 2017-12-29 | Anti-coagulation factor xi antibody |
| JP2019543277A JP7271430B2 (ja) | 2017-02-10 | 2017-12-29 | 抗ｘｉ因子抗体 |
| MX2019009500A MX2019009500A (es) | 2017-02-10 | 2017-12-29 | Anticuerpos anti factor de coagulación xi. |
| BR112019016300-0A BR112019016300A2 (pt) | 2017-02-10 | 2017-12-29 | ANTICORPO ANTI-FXI OU ANTI-FXIa ISOLADO, SEU USO E MÉTODO DE PREPARAÇÃO, COMPOSIÇÃO FARMACÊUTICA E ANTICORPO OU UM FRAGMENTO FUNCIONAL DO MESMO OU UMA PORÇÃO IMUNOLOGICAMENTE ATIVA DO MESMO |
| AU2017397778A AU2017397778B2 (en) | 2017-02-10 | 2017-12-29 | Anti-coagulation factor XI antibody |
| KR1020197025752A KR102690437B1 (ko) | 2017-02-10 | 2017-12-29 | 항-응고 인자 xi 항체 |
| PCT/CN2017/119856 WO2018145533A1 (zh) | 2017-02-10 | 2017-12-29 | 抗凝血因子xi抗体 |
| CA3054322A CA3054322A1 (en) | 2017-02-10 | 2017-12-29 | Anti-coagulation factor xi antibodies |
| US16/537,427 US11958911B2 (en) | 2017-02-10 | 2019-08-09 | Anti-coagulation factor XI antibody |
| AU2025203303A AU2025203303A1 (en) | 2017-02-10 | 2025-05-08 | Anti-coagulation factor XI antibody |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710073984.XA CN108409863B (zh) | 2017-02-10 | 2017-02-10 | 抗凝血因子xi抗体 |
Publications (2)
| Publication Number | Publication Date |
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| CN108409863A CN108409863A (zh) | 2018-08-17 |
| CN108409863B true CN108409863B (zh) | 2023-09-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710073984.XA Active CN108409863B (zh) | 2017-02-10 | 2017-02-10 | 抗凝血因子xi抗体 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP3581587B1 (enExample) |
| JP (1) | JP7271430B2 (enExample) |
| KR (1) | KR102690437B1 (enExample) |
| CN (1) | CN108409863B (enExample) |
| AU (2) | AU2017397778B2 (enExample) |
| BR (1) | BR112019016300A2 (enExample) |
| CA (1) | CA3054322A1 (enExample) |
| MX (1) | MX2019009500A (enExample) |
| WO (1) | WO2018145533A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020029179A1 (en) * | 2018-08-09 | 2020-02-13 | Shanghai Benemae Pharmaceutical Corporation | Anti-factor xi antibodies |
| US11958911B2 (en) | 2017-02-10 | 2024-04-16 | Shanghai Benemae Pharmaceutical | Anti-coagulation factor XI antibody |
| CN110878123B (zh) * | 2018-09-05 | 2022-08-23 | 华瑞同康生物技术（深圳）有限公司 | 一种抗tk1原核重组单链抗体及制备方法 |
| EP3914624A4 (en) * | 2019-01-21 | 2022-10-19 | Aronora, Inc. | NOVEL HUMANIZED ANTIBODIES AGAINST FACTOR XI HAVING ANTI-THROMBOTIC AND ANTI-INFLAMMATORY EFFECTS AND ASSOCIATED USES |
| CN113474374B (zh) * | 2019-04-16 | 2025-05-02 | 四川科伦博泰生物医药股份有限公司 | 抗FXI/FXIa抗体及其用途 |
| CN110423278B (zh) | 2019-08-08 | 2020-07-17 | 上海博槿生物科技有限公司 | 一种抗凝血因子XI活化形式因子XIa的抗体及其制备方法和应用 |
| CN110498839A (zh) * | 2019-09-19 | 2019-11-26 | 河南省农业科学院 | 氟罗沙星单链抗体关键多肽序列及应用 |
| JP2023106635A (ja) | 2020-04-17 | 2023-08-02 | 中外製薬株式会社 | 二重特異性抗原結合分子ならびに、それに関連する組成物、組成物の製造のための使用、キット、および方法 |
| TWI882142B (zh) * | 2020-07-02 | 2025-05-01 | 大陸商北京拓界生物醫藥科技有限公司 | 抗FXI/FXIa抗體、其抗原結合片段及醫藥用途 |
| CN116589588B (zh) * | 2023-04-14 | 2023-12-22 | 北京基科晟斯医药科技有限公司 | 结合凝血因子x的抗体 |
| WO2025130748A1 (zh) * | 2023-12-22 | 2025-06-26 | 四川科伦博泰生物医药股份有限公司 | 一种抗凝血因子XI/XIa抗体制剂 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03228690A (ja) * | 1990-02-02 | 1991-10-09 | Dai Ichi Pure Chem Co Ltd | 血液凝固第１０３因子に対するモノクロナール抗体 |
| WO2009067660A2 (en) * | 2007-11-21 | 2009-05-28 | Oregon Health & Science University | Anti-factor xi monoclonal antibodies and methods of use thereof |
| HK1207091A1 (en) * | 2012-05-10 | 2016-01-22 | Bayer Pharma Aktiengesellschaft | Antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and uses thereof |
| WO2017015619A1 (en) * | 2015-07-23 | 2017-01-26 | The Regents Of The University Of California | Antibodies to coagulation factor xia and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100925348B1 (ko) * | 2001-06-12 | 2009-11-09 | 자이단호진 가가쿠오요비겟세이료호겐쿠쇼 | 인간형 항-혈액 응고 인자 ⅷ 항체 |
| DE10205520A1 (de) * | 2002-02-08 | 2003-08-14 | Aventis Behring Gmbh | Inhibitorischer, monoklonaler Antikörper gegen die den Blutgerinnungsfaktor VII aktivierende Protease |
| AU2009335643B2 (en) * | 2008-12-18 | 2014-05-29 | Oregon Health & Science University | Anti-fXI antibodies and methods of use |
| JOP20200312A1 (ar) * | 2015-06-26 | 2017-06-16 | Novartis Ag | الأجسام المضادة للعامل xi وطرق الاستخدام |
-
2017
- 2017-02-10 CN CN201710073984.XA patent/CN108409863B/zh active Active
- 2017-12-29 CA CA3054322A patent/CA3054322A1/en active Pending
- 2017-12-29 MX MX2019009500A patent/MX2019009500A/es unknown
- 2017-12-29 AU AU2017397778A patent/AU2017397778B2/en active Active
- 2017-12-29 BR BR112019016300-0A patent/BR112019016300A2/pt unknown
- 2017-12-29 JP JP2019543277A patent/JP7271430B2/ja active Active
- 2017-12-29 EP EP17895532.4A patent/EP3581587B1/en active Active
- 2017-12-29 WO PCT/CN2017/119856 patent/WO2018145533A1/zh not_active Ceased
- 2017-12-29 KR KR1020197025752A patent/KR102690437B1/ko active Active
-
2025
- 2025-05-08 AU AU2025203303A patent/AU2025203303A1/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03228690A (ja) * | 1990-02-02 | 1991-10-09 | Dai Ichi Pure Chem Co Ltd | 血液凝固第１０３因子に対するモノクロナール抗体 |
| WO2009067660A2 (en) * | 2007-11-21 | 2009-05-28 | Oregon Health & Science University | Anti-factor xi monoclonal antibodies and methods of use thereof |
| HK1207091A1 (en) * | 2012-05-10 | 2016-01-22 | Bayer Pharma Aktiengesellschaft | Antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and uses thereof |
| WO2017015619A1 (en) * | 2015-07-23 | 2017-01-26 | The Regents Of The University Of California | Antibodies to coagulation factor xia and uses thereof |
Non-Patent Citations (3)
| Title |
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| Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis;C Zhong;《Journal of Thrombosis and Haemostasis》;20161224;第15卷(第1期);第122-130页 * |
| Factor XIa inhibitors: A review of the patent literature;Rami A Al-Horani;《Expert Opinion on Therapeutic Patents》;20160225;第26卷(第3期);第323-345页 * |
| Safety and efficacy of factor XI (FXI) concentrate use in patients with FXI deficiency: a single-centre experience of 19 years;G Ling;《Haemophilia：the offical journal of the World Federation of Hemophilia》;20151209;第22卷(第3期);第411-418 * |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20190116990A (ko) | 2019-10-15 |
| MX2019009500A (es) | 2020-01-30 |
| JP7271430B2 (ja) | 2023-05-11 |
| EP3581587A1 (en) | 2019-12-18 |
| KR102690437B1 (ko) | 2024-07-30 |
| AU2025203303A1 (en) | 2025-05-29 |
| EP3581587A4 (en) | 2021-03-31 |
| CN108409863A (zh) | 2018-08-17 |
| AU2017397778A1 (en) | 2019-10-03 |
| WO2018145533A1 (zh) | 2018-08-16 |
| RU2019128423A3 (enExample) | 2021-03-19 |
| EP3581587B1 (en) | 2025-02-05 |
| CA3054322A1 (en) | 2018-08-16 |
| JP2020507578A (ja) | 2020-03-12 |
| AU2017397778B2 (en) | 2025-03-06 |
| BR112019016300A2 (pt) | 2020-06-16 |
| RU2019128423A (ru) | 2021-03-10 |
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