JP2020507561A5 - - Google Patents
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- JP2020507561A5 JP2020507561A5 JP2019538396A JP2019538396A JP2020507561A5 JP 2020507561 A5 JP2020507561 A5 JP 2020507561A5 JP 2019538396 A JP2019538396 A JP 2019538396A JP 2019538396 A JP2019538396 A JP 2019538396A JP 2020507561 A5 JP2020507561 A5 JP 2020507561A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding fragment
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022107980A JP2022153405A (ja) | 2017-01-30 | 2022-07-04 | 一価の抗プロペルジン抗体および抗体断片 |
| JP2024095141A JP2024116321A (ja) | 2017-01-30 | 2024-06-12 | 一価の抗プロペルジン抗体および抗体断片 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762452187P | 2017-01-30 | 2017-01-30 | |
| US62/452,187 | 2017-01-30 | ||
| PCT/US2018/015985 WO2018140956A1 (en) | 2017-01-30 | 2018-01-30 | Monovalent anti-properdin antibodies and antibody fragments |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022107980A Division JP2022153405A (ja) | 2017-01-30 | 2022-07-04 | 一価の抗プロペルジン抗体および抗体断片 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020507561A JP2020507561A (ja) | 2020-03-12 |
| JP2020507561A5 true JP2020507561A5 (https=) | 2021-03-04 |
| JP7101684B2 JP7101684B2 (ja) | 2022-07-15 |
Family
ID=62978808
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019538396A Active JP7101684B2 (ja) | 2017-01-30 | 2018-01-30 | 一価の抗プロペルジン抗体および抗体断片 |
| JP2022107980A Pending JP2022153405A (ja) | 2017-01-30 | 2022-07-04 | 一価の抗プロペルジン抗体および抗体断片 |
| JP2024095141A Pending JP2024116321A (ja) | 2017-01-30 | 2024-06-12 | 一価の抗プロペルジン抗体および抗体断片 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022107980A Pending JP2022153405A (ja) | 2017-01-30 | 2022-07-04 | 一価の抗プロペルジン抗体および抗体断片 |
| JP2024095141A Pending JP2024116321A (ja) | 2017-01-30 | 2024-06-12 | 一価の抗プロペルジン抗体および抗体断片 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11198725B2 (https=) |
| EP (1) | EP3573661A4 (https=) |
| JP (3) | JP7101684B2 (https=) |
| KR (2) | KR20230173731A (https=) |
| CN (2) | CN118184777A (https=) |
| AU (2) | AU2018212012B2 (https=) |
| BR (1) | BR112019014652A2 (https=) |
| CA (1) | CA3049806A1 (https=) |
| CO (1) | CO2019007686A2 (https=) |
| IL (2) | IL309890A (https=) |
| MX (3) | MX2019008827A (https=) |
| WO (1) | WO2018140956A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118184777A (zh) * | 2017-01-30 | 2024-06-14 | 亚力兄制药公司 | 单价抗备解素抗体及抗体片段 |
| BR112019028269A2 (pt) | 2017-07-11 | 2020-07-14 | Alexion Pharmaceuticals, Inc. | polipeptídeos que se ligam ao componente c5 do complemento ou à albumina sérica e suas proteínas de fusão |
| JP7222075B2 (ja) * | 2018-09-13 | 2023-02-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Ｃ３糸球体症のモデルとしての補体因子ｈ遺伝子ノックアウトラット |
| CN115003694A (zh) * | 2020-01-08 | 2022-09-02 | 载度思生命科学有限公司 | 抗备解素抗体及其制备 |
| WO2022066774A1 (en) | 2020-09-23 | 2022-03-31 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement mediated disorders |
| CN114432449B (zh) * | 2020-10-30 | 2024-05-28 | 广州市妇女儿童医疗中心 | 用于抑制mhc-i和/或ii信号通路的试剂在治疗胆道闭锁中的应用 |
| WO2023023227A1 (en) | 2021-08-20 | 2023-02-23 | Alexion Pharmaceuticals, Inc. | Methods for treating sickle cell disease or beta thalassemia using complement alternative pathway inhibitors |
| US11981727B2 (en) | 2021-08-31 | 2024-05-14 | Novelmed Therapeutics, Inc | Monospecific and bispecific antibodies and antigen binding fragments thereof |
| WO2024108529A1 (en) * | 2022-11-25 | 2024-05-30 | Linno Pharmaceuticals Inc. | Properdin binding protein and use thereof |
| TW202413435A (zh) * | 2022-08-05 | 2024-04-01 | 美商艾力克森製藥公司 | 融合蛋白的藥物組成物及其使用方法 |
| TW202417490A (zh) * | 2022-08-31 | 2024-05-01 | 美商艾力克森製藥公司 | 用於治療鐮狀細胞病的融合多肽之劑量及投與 |
| EP4395825A4 (en) * | 2022-11-25 | 2025-08-20 | Linno Pharmaceuticals Inc | PROPERDIN-BINDING PROTEIN AND ITS USE |
| CN120399074B (zh) * | 2023-06-02 | 2025-12-30 | 安徽金百奥生物科技有限公司 | 一种与人dr3胞外域高亲和力的纳米抗体 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101289511A (zh) | 2000-04-11 | 2008-10-22 | 杰南技术公司 | 多价抗体及其应用 |
| US7423128B2 (en) | 2004-11-03 | 2008-09-09 | Amgen Fremont Inc. | Anti-properdin antibodies, and methods for making and using same |
| WO2006081249A2 (en) | 2005-01-25 | 2006-08-03 | Cell Therapeutics, Inc. | Conjugates of biologically active proteins having a modified in vivo half-life |
| US7612181B2 (en) | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| EP3299027A1 (en) | 2005-11-04 | 2018-03-28 | Genentech, Inc. | Use of complement pathway inhibitors to treat ocular diseases |
| GB0624500D0 (en) * | 2006-12-07 | 2007-01-17 | Istituto Superiore Di Sanito | A novel passive vaccine for candida infections |
| US8435512B2 (en) * | 2008-03-03 | 2013-05-07 | Novelmed Therapeutics, Inc. | Anti-properdin antibodies |
| NZ597259A (en) | 2009-06-23 | 2014-04-30 | Alexion Pharma Inc | Bispecific antibodies that bind to complement proteins |
| US20110172398A1 (en) | 2009-10-02 | 2011-07-14 | Boehringer Ingelheim International Gmbh | Bispecific binding molecules for anti-angiogenesis therapy |
| AU2011224224B2 (en) * | 2010-03-10 | 2015-07-09 | Novelmed Therapeutics, Inc. | Humanized and chimeric anti-properdin antibodies |
| ES2630031T3 (es) | 2010-09-28 | 2017-08-17 | Aegerion Pharmaceuticals, Inc. | Un polipéptido de leptina pinnípedo-humano quimérico con solubilidad aumentada |
| EA202092589A3 (ru) | 2010-11-08 | 2021-06-30 | Аблинкс Н.В. | Cxcr2-связывающие полипептиды |
| JP6293659B2 (ja) | 2011-07-01 | 2018-03-14 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 抗プロペルジン抗体およびその使用 |
| JP6006309B2 (ja) | 2011-07-08 | 2016-10-12 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド |
| PE20150159A1 (es) * | 2011-12-21 | 2015-02-08 | Novartis Ag | Composiciones y metodos para anticuerpos que actuan sobre el factor p |
| CN104114187A (zh) * | 2011-12-28 | 2014-10-22 | 诺沃姆德治疗公司 | 去糖基化的人类抗体、其融合蛋白质及用途 |
| EP2904014A4 (en) | 2012-10-04 | 2016-09-28 | Novelmed Therapeutics Inc | FOR ALTERNATIVE PATHS, SPECIFIC ANTIBODIES FOR THE TREATMENT OF HEMOLYTIC DISEASES |
| NL2013661B1 (en) | 2014-10-21 | 2016-10-05 | Ablynx Nv | KV1.3 Binding immunoglobulins. |
| CA2874083C (en) * | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
| CN118184777A (zh) * | 2017-01-30 | 2024-06-14 | 亚力兄制药公司 | 单价抗备解素抗体及抗体片段 |
| CN110003335B (zh) * | 2019-04-12 | 2023-07-04 | 深圳普瑞金生物药业股份有限公司 | Cd47单域抗体、核酸及试剂盒 |
-
2018
- 2018-01-30 CN CN202410325026.7A patent/CN118184777A/zh active Pending
- 2018-01-30 CA CA3049806A patent/CA3049806A1/en active Pending
- 2018-01-30 MX MX2019008827A patent/MX2019008827A/es unknown
- 2018-01-30 IL IL309890A patent/IL309890A/en unknown
- 2018-01-30 WO PCT/US2018/015985 patent/WO2018140956A1/en not_active Ceased
- 2018-01-30 EP EP18744926.9A patent/EP3573661A4/en active Pending
- 2018-01-30 AU AU2018212012A patent/AU2018212012B2/en active Active
- 2018-01-30 KR KR1020237042534A patent/KR20230173731A/ko not_active Ceased
- 2018-01-30 US US16/479,335 patent/US11198725B2/en active Active
- 2018-01-30 KR KR1020197021910A patent/KR102613874B1/ko active Active
- 2018-01-30 BR BR112019014652-0A patent/BR112019014652A2/pt active Search and Examination
- 2018-01-30 JP JP2019538396A patent/JP7101684B2/ja active Active
- 2018-01-30 IL IL267898A patent/IL267898B2/en unknown
- 2018-01-30 CN CN201880008892.6A patent/CN110831626B/zh active Active
-
2019
- 2019-07-17 CO CONC2019/0007686A patent/CO2019007686A2/es unknown
- 2019-07-25 MX MX2023004333A patent/MX2023004333A/es unknown
- 2019-07-25 MX MX2023007840A patent/MX2023007840A/es unknown
-
2021
- 2021-11-09 US US17/522,028 patent/US12497445B2/en active Active
-
2022
- 2022-07-04 JP JP2022107980A patent/JP2022153405A/ja active Pending
-
2024
- 2024-06-12 JP JP2024095141A patent/JP2024116321A/ja active Pending
-
2025
- 2025-02-03 AU AU2025200709A patent/AU2025200709A1/en active Pending
- 2025-11-13 US US19/387,895 patent/US20260070963A1/en active Pending
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