JP2022153405A5 - - Google Patents

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Publication number
JP2022153405A5
JP2022153405A5 JP2022107980A JP2022107980A JP2022153405A5 JP 2022153405 A5 JP2022153405 A5 JP 2022153405A5 JP 2022107980 A JP2022107980 A JP 2022107980A JP 2022107980 A JP2022107980 A JP 2022107980A JP 2022153405 A5 JP2022153405 A5 JP 2022153405A5
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JP
Japan
Prior art keywords
antigen
binding fragment
antibody
seq
monovalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022107980A
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English (en)
Japanese (ja)
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JP2022153405A (ja
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Publication date
Priority claimed from JP2019538396A external-priority patent/JP7101684B2/ja
Application filed filed Critical
Publication of JP2022153405A publication Critical patent/JP2022153405A/ja
Publication of JP2022153405A5 publication Critical patent/JP2022153405A5/ja
Priority to JP2024095141A priority Critical patent/JP2024116321A/ja
Pending legal-status Critical Current

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JP2022107980A 2017-01-30 2022-07-04 一価の抗プロペルジン抗体および抗体断片 Pending JP2022153405A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024095141A JP2024116321A (ja) 2017-01-30 2024-06-12 一価の抗プロペルジン抗体および抗体断片

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762452187P 2017-01-30 2017-01-30
US62/452,187 2017-01-30
JP2019538396A JP7101684B2 (ja) 2017-01-30 2018-01-30 一価の抗プロペルジン抗体および抗体断片
PCT/US2018/015985 WO2018140956A1 (en) 2017-01-30 2018-01-30 Monovalent anti-properdin antibodies and antibody fragments

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019538396A Division JP7101684B2 (ja) 2017-01-30 2018-01-30 一価の抗プロペルジン抗体および抗体断片

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024095141A Division JP2024116321A (ja) 2017-01-30 2024-06-12 一価の抗プロペルジン抗体および抗体断片

Publications (2)

Publication Number Publication Date
JP2022153405A JP2022153405A (ja) 2022-10-12
JP2022153405A5 true JP2022153405A5 (https=) 2023-04-26

Family

ID=62978808

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019538396A Active JP7101684B2 (ja) 2017-01-30 2018-01-30 一価の抗プロペルジン抗体および抗体断片
JP2022107980A Pending JP2022153405A (ja) 2017-01-30 2022-07-04 一価の抗プロペルジン抗体および抗体断片
JP2024095141A Pending JP2024116321A (ja) 2017-01-30 2024-06-12 一価の抗プロペルジン抗体および抗体断片

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2019538396A Active JP7101684B2 (ja) 2017-01-30 2018-01-30 一価の抗プロペルジン抗体および抗体断片

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024095141A Pending JP2024116321A (ja) 2017-01-30 2024-06-12 一価の抗プロペルジン抗体および抗体断片

Country Status (12)

Country Link
US (3) US11198725B2 (https=)
EP (1) EP3573661A4 (https=)
JP (3) JP7101684B2 (https=)
KR (2) KR102613874B1 (https=)
CN (2) CN110831626B (https=)
AU (2) AU2018212012B2 (https=)
BR (1) BR112019014652A2 (https=)
CA (1) CA3049806A1 (https=)
CO (1) CO2019007686A2 (https=)
IL (2) IL267898B2 (https=)
MX (3) MX2019008827A (https=)
WO (1) WO2018140956A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019008827A (es) * 2017-01-30 2019-09-26 Alexion Pharma Inc Anticuerpos anti-properdina monovalentes y fragmentos de anticuerpo.
KR102806328B1 (ko) * 2017-07-11 2025-05-14 알렉시온 파마슈티칼스, 인코포레이티드 보체 성분 c5 또는 혈청 알부민에 결합하는 폴리펩티드 및 그의 융합 단백질
JP7222075B2 (ja) * 2018-09-13 2023-02-14 リジェネロン・ファーマシューティカルズ・インコーポレイテッド C3糸球体症のモデルとしての補体因子h遺伝子ノックアウトラット
US12570732B2 (en) 2020-01-08 2026-03-10 Zydus Lifesciences Limited Anti-properdin antibodies and preparation thereof
CN116437913A (zh) 2020-09-23 2023-07-14 艾其林医药公司 用于治疗补体介导的病症的药物化合物
CN118436786A (zh) * 2020-10-30 2024-08-06 广州市妇女儿童医疗中心 诊治胆道闭锁的方法
WO2023023227A1 (en) 2021-08-20 2023-02-23 Alexion Pharmaceuticals, Inc. Methods for treating sickle cell disease or beta thalassemia using complement alternative pathway inhibitors
US11981727B2 (en) 2021-08-31 2024-05-14 Novelmed Therapeutics, Inc Monospecific and bispecific antibodies and antigen binding fragments thereof
WO2024108529A1 (en) * 2022-11-25 2024-05-30 Linno Pharmaceuticals Inc. Properdin binding protein and use thereof
CA3264087A1 (en) * 2022-08-05 2024-02-08 Alexion Pharmaceuticals, Inc. Pharmaceutical compositions based on fusion proteins and their methods of use
CN120018862A (zh) * 2022-08-31 2025-05-16 阿雷克森制药公司 用于治疗镰状细胞病的融合多肽的剂量和施用
KR20250112858A (ko) 2022-11-25 2025-07-24 리노 파마슈티컬스 아이엔씨. 프로퍼딘 결합 단백질 및 이의 용도
CN120399074B (zh) * 2023-06-02 2025-12-30 安徽金百奥生物科技有限公司 一种与人dr3胞外域高亲和力的纳米抗体

Family Cites Families (21)

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Publication number Priority date Publication date Assignee Title
JP2003531588A (ja) 2000-04-11 2003-10-28 ジェネンテック・インコーポレーテッド 多価抗体とその用途
US7423128B2 (en) 2004-11-03 2008-09-09 Amgen Fremont Inc. Anti-properdin antibodies, and methods for making and using same
BRPI0606934A2 (pt) 2005-01-25 2017-07-11 Cell Therapeutics Inc Conjugado de proteína biologicamente ativa, composição, molécula de dna quimérica, vetor, célula, e, métodos para preparar conjugado de proteína biologicamente ativa, e para determinar se um dado conjugado de proteína exibe uma meia-vida de plasma modificada comparada com a meia-vida intrínseca do polipeptídeo biologicamente ativo não conjungado
US7612181B2 (en) 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
SG10201804008UA (en) * 2005-11-04 2018-06-28 Genentech Inc Use of complement pathway inhibitors to treat ocular diseases
GB0624500D0 (en) * 2006-12-07 2007-01-17 Istituto Superiore Di Sanito A novel passive vaccine for candida infections
DK2262831T3 (en) * 2008-03-03 2015-04-27 Novelmed Therapeutics Inc ANTI-Properdin ANTIBODIES
CA2766565A1 (en) 2009-06-23 2010-12-29 Alexion Pharmaceuticals, Inc. Bispecific antibodies that bind to complement proteins
US20110172398A1 (en) 2009-10-02 2011-07-14 Boehringer Ingelheim International Gmbh Bispecific binding molecules for anti-angiogenesis therapy
CA2811221C (en) * 2010-03-10 2018-01-09 Novelmed Therapeutics, Inc. Humanized and chimeric anti-properdin antibodies
PT2621515T (pt) 2010-09-28 2017-07-12 Aegerion Pharmaceuticals Inc Polipéptido quimérico de leptina de foca-ser humano com solubilidade aumentada
AU2011328246B2 (en) 2010-11-08 2016-06-30 Ablynx N.V. CXCR2 binding polypeptides
KR20140064768A (ko) 2011-07-01 2014-05-28 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 항-프로퍼딘 항체 및 그의 용도
JP6006309B2 (ja) 2011-07-08 2016-10-12 アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc 作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド
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MX2019008827A (es) * 2017-01-30 2019-09-26 Alexion Pharma Inc Anticuerpos anti-properdina monovalentes y fragmentos de anticuerpo.
CN110003335B (zh) * 2019-04-12 2023-07-04 深圳普瑞金生物药业股份有限公司 Cd47单域抗体、核酸及试剂盒

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