JP2020505025A - 免疫工学的な改変をした多能性細胞 - Google Patents

免疫工学的な改変をした多能性細胞 Download PDF

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JP2020505025A
JP2020505025A JP2019538202A JP2019538202A JP2020505025A JP 2020505025 A JP2020505025 A JP 2020505025A JP 2019538202 A JP2019538202 A JP 2019538202A JP 2019538202 A JP2019538202 A JP 2019538202A JP 2020505025 A JP2020505025 A JP 2020505025A
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protein
cells
hla
gene
expression
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JP2020505025A5 (OSRAM
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シュレプファー ソニヤ
シュレプファー ソニヤ
デュース トバイアス
デュース トバイアス
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University of California
University of California Berkeley
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University of California San Diego UCSD
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Priority to JP2025003516A priority patent/JP2025069169A/ja
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JP2019538202A 2017-01-13 2018-01-14 免疫工学的な改変をした多能性細胞 Pending JP2020505025A (ja)

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JP2022208126A JP2023052079A (ja) 2017-01-13 2022-12-26 免疫工学的な改変をした多能性細胞
JP2025003516A JP2025069169A (ja) 2017-01-13 2025-01-09 免疫工学的な改変をした多能性細胞

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US201762445969P 2017-01-13 2017-01-13
US62/445,969 2017-01-13
PCT/US2018/013688 WO2018132783A1 (en) 2017-01-13 2018-01-14 Immunoengineered pluripotent cells

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JP2025003516A Pending JP2025069169A (ja) 2017-01-13 2025-01-09 免疫工学的な改変をした多能性細胞

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US (2) US20190376045A1 (OSRAM)
EP (1) EP3568464A1 (OSRAM)
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KR (2) KR20190103373A (OSRAM)
CN (1) CN110177869A (OSRAM)
AU (2) AU2018207649B2 (OSRAM)
BR (1) BR112019014257A2 (OSRAM)
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Cited By (6)

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WO2022191216A1 (ja) * 2021-03-09 2022-09-15 国立研究開発法人理化学研究所 低免疫原性網膜色素上皮細胞の製造方法
JP2023052079A (ja) * 2017-01-13 2023-04-11 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 免疫工学的な改変をした多能性細胞
JP2023520997A (ja) * 2020-03-25 2023-05-23 サナ バイオテクノロジー,インコーポレイテッド 神経学的障害及び神経学的病態の処置のための低免疫原性神経細胞
JP2023521157A (ja) * 2020-04-06 2023-05-23 アールエックスセル インコーポレーテッド 低免疫原性の細胞ならびにそれらの産生のための方法および組成物
JP2023545056A (ja) * 2020-10-09 2023-10-26 サナ バイオテクノロジー,インコーポレイテッド CD47-SIRPα封鎖剤を使用して安全殺傷機構を誘発する方法
JP2023552441A (ja) * 2020-12-07 2023-12-15 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア SIRP-αエンゲージャーによる自然免疫細胞のサイレンシング

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EP3601528A4 (en) * 2017-03-20 2021-05-05 Washington University CELLS AND METHODS OF USE AND PRODUCTION OF THEM
JP2020513832A (ja) 2017-03-22 2020-05-21 ノバルティス アーゲー 免疫腫瘍学のための組成物および方法
GB2588249B (en) 2017-06-12 2023-01-04 Sinai Health Sys Allograft tolerance without the need for systemic immune suppression
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CA3106022A1 (en) * 2018-07-17 2020-01-23 The Regents Of The University Of California Chimeric antigen receptor t cells derived from immunoengineered pluripotent stem cells
BR112021000637A2 (pt) * 2018-07-17 2021-04-13 The Regents Of The University Of California Célula cardíaca hipoimune isolada, método para tratar um paciente que sofre de uma afecção ou doença cardíaca, método para produzir uma população de células cardíacas hipoimunes, célula endotelial hipoimune isolada, método para tratar um paciente que sofre de uma afecção ou doença vascular, método para produzir uma população de células endoteliais hipoimunes, neurônio dopaminérgico hipoimune isolado, método para tratar um paciente que sofre de uma doença ou afecção neurodegenerativa, método para produzir uma população de neurônios dopaminérgicos hipoimunes, célula de ilhota pancreática hipoimune isolada, método para tratar um paciente que sofre de diabetes, método para produzir uma população de células de ilhota pancreática hipoimunes, célula de epitélio pigmentado da retina (rpe) hipoimune isolada, método para tratar um paciente que sofre de uma afecção ocular, e método para produzir uma população de células de epitélio pigmentado da retina (rpe) hipoimunes
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CN111424016A (zh) * 2019-01-09 2020-07-17 复旦大学 降低细胞免疫原性的诱导型多能干细胞系及建立方法
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EP3990627A4 (en) 2019-06-26 2023-07-19 The Regents of The University of California SIRP-ALPHA SILENCED NATURAL KILLER CELLS (NK)
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CN114525255A (zh) * 2020-10-30 2022-05-24 未来智人再生医学研究院(广州)有限公司 一种表达il-11的多能干细胞衍生物及其应用
CN114457021A (zh) * 2020-10-30 2022-05-10 未来智人再生医学研究院(广州)有限公司 一种表达cd47抗体的多能干细胞及其衍生物与应用
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CN114107211B (zh) * 2020-12-04 2025-09-30 未来智人再生医学研究院(广州)有限公司 一种多能干细胞及其衍生物
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JP2024501971A (ja) 2020-12-31 2024-01-17 サナ バイオテクノロジー,インコーポレイテッド Car-t活性を調節するための方法及び組成物
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