JP2020502142A5 - - Google Patents

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JP2020502142A5
JP2020502142A5 JP2019531922A JP2019531922A JP2020502142A5 JP 2020502142 A5 JP2020502142 A5 JP 2020502142A5 JP 2019531922 A JP2019531922 A JP 2019531922A JP 2019531922 A JP2019531922 A JP 2019531922A JP 2020502142 A5 JP2020502142 A5 JP 2020502142A5
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pharmaceutical composition
composition according
human subject
double
rnai agent
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JP2019531922A
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JP7058656B2 (ja
JP2020502142A (ja
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Priority claimed from PCT/US2017/066631 external-priority patent/WO2018112320A1/en
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Priority to JP2022002865A priority Critical patent/JP2022062035A/ja
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Publication of JP7058656B2 publication Critical patent/JP7058656B2/ja
Priority to JP2023151150A priority patent/JP2024009806A/ja
Priority to JP2025066193A priority patent/JP2025118649A/ja
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JP2019531922A 2016-12-16 2017-12-15 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法 Active JP7058656B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2022002865A JP2022062035A (ja) 2016-12-16 2022-01-12 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2023151150A JP2024009806A (ja) 2016-12-16 2023-09-19 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2025066193A JP2025118649A (ja) 2016-12-16 2025-04-14 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662435127P 2016-12-16 2016-12-16
US62/435,127 2016-12-16
PCT/US2017/066631 WO2018112320A1 (en) 2016-12-16 2017-12-15 Methods for treating or preventing ttr-associated diseases using transthyretin (ttr) irna compositions

Related Child Applications (1)

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JP2022002865A Division JP2022062035A (ja) 2016-12-16 2022-01-12 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法

Publications (3)

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JP2020502142A JP2020502142A (ja) 2020-01-23
JP2020502142A5 true JP2020502142A5 (enExample) 2021-01-28
JP7058656B2 JP7058656B2 (ja) 2022-04-22

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JP2019531922A Active JP7058656B2 (ja) 2016-12-16 2017-12-15 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2022002865A Pending JP2022062035A (ja) 2016-12-16 2022-01-12 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2023151150A Withdrawn JP2024009806A (ja) 2016-12-16 2023-09-19 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2025066193A Pending JP2025118649A (ja) 2016-12-16 2025-04-14 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法

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JP2022002865A Pending JP2022062035A (ja) 2016-12-16 2022-01-12 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2023151150A Withdrawn JP2024009806A (ja) 2016-12-16 2023-09-19 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法
JP2025066193A Pending JP2025118649A (ja) 2016-12-16 2025-04-14 トランスサイレチン(TTR)iRNA組成物を用いてTTR関連疾患を治療または予防するための方法

Country Status (9)

Country Link
US (2) US20190350962A1 (enExample)
EP (1) EP3555292A1 (enExample)
JP (4) JP7058656B2 (enExample)
KR (2) KR20190098181A (enExample)
AU (2) AU2017376950B2 (enExample)
SG (1) SG10201913552UA (enExample)
TW (2) TWI865997B (enExample)
WO (1) WO2018112320A1 (enExample)
ZA (1) ZA202306507B (enExample)

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IL305418A (en) * 2021-03-04 2023-10-01 Alnylam Pharmaceuticals Inc Angiopoietin-like 3 (ANGPTL3) IRNA compositions and methods of using them
EP4351541A2 (en) 2021-06-08 2024-04-17 Alnylam Pharmaceuticals, Inc. Compositions and methods for treating or preventing stargardt's disease and/or retinal binding protein 4 (rbp4)-associated disorders
CA3227852A1 (en) 2021-08-03 2023-02-09 Alnylam Pharmaceuticals, Inc. Transthyretin (ttr) irna compositions and methods of use thereof
IL317824A (en) * 2022-07-11 2025-02-01 Sanegene Bio Usa Inc Ribose derivatives modified at the '2' position and methods of use
EP4562150A2 (en) * 2022-07-27 2025-06-04 E-Therapeutics plc Nucleic acid compounds
CN120265776A (zh) * 2022-12-05 2025-07-04 美国礼来公司 经修饰的寡核苷酸
JP2025541245A (ja) * 2022-12-16 2025-12-18 アムジェン インコーポレイテッド Ttr発現を阻害するためのrnaiコンストラクト及びその使用方法
WO2024138111A1 (en) * 2022-12-23 2024-06-27 Eli Lilly And Company Novel rna therapeutics and uses thereof
KR20250124884A (ko) * 2022-12-23 2025-08-20 일라이 릴리 앤드 캄파니 신규 rna 치료제 및 그의 용도
WO2025128632A1 (en) * 2023-12-12 2025-06-19 Alnylam Pharmaceuticals, Inc. Methods and compositions for treating ketohexokinase (khk)-associated diseases
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