JP2020500868A5 - - Google Patents
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- Publication number
- JP2020500868A5 JP2020500868A5 JP2019529165A JP2019529165A JP2020500868A5 JP 2020500868 A5 JP2020500868 A5 JP 2020500868A5 JP 2019529165 A JP2019529165 A JP 2019529165A JP 2019529165 A JP2019529165 A JP 2019529165A JP 2020500868 A5 JP2020500868 A5 JP 2020500868A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- mixture
- oral
- dosage form
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- OXVFDZYQLGRLCD-UHFFFAOYSA-N CC(c1cnc(CCOc2ccc(CC(C(N3)=O)SC3=O)cc2)cc1)O Chemical compound CC(c1cnc(CCOc2ccc(CC(C(N3)=O)SC3=O)cc2)cc1)O OXVFDZYQLGRLCD-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16382584.7 | 2016-12-01 | ||
| EP16382584 | 2016-12-01 | ||
| PCT/IB2017/057587 WO2018100557A1 (en) | 2016-12-01 | 2017-12-01 | 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine- 2,4-dione for treating nonalcoholic fatty liver disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020500868A JP2020500868A (ja) | 2020-01-16 |
| JP2020500868A5 true JP2020500868A5 (enExample) | 2021-01-21 |
| JP7040798B2 JP7040798B2 (ja) | 2022-03-23 |
Family
ID=57517838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019529165A Expired - Fee Related JP7040798B2 (ja) | 2016-12-01 | 2017-12-01 | 非アルコール性脂肪性肝疾患を処置するための５－［［４－［２－［５－（１－ヒドロキシエチル）ピリジン－２－イル］エトキシ］フェニル］メチル］－１，３－チアゾリジン－２，４－ジオン |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11938122B2 (enExample) |
| EP (1) | EP3548026B1 (enExample) |
| JP (1) | JP7040798B2 (enExample) |
| KR (1) | KR102595034B1 (enExample) |
| CN (1) | CN110022877B (enExample) |
| AU (1) | AU2017370003B2 (enExample) |
| BR (1) | BR112019011334A2 (enExample) |
| CA (1) | CA3044364A1 (enExample) |
| CY (1) | CY1124116T1 (enExample) |
| DK (1) | DK3548026T3 (enExample) |
| EA (1) | EA201991304A1 (enExample) |
| ES (1) | ES2867300T3 (enExample) |
| HR (1) | HRP20210576T1 (enExample) |
| HU (1) | HUE054346T2 (enExample) |
| LT (1) | LT3548026T (enExample) |
| MX (1) | MX379710B (enExample) |
| PL (1) | PL3548026T3 (enExample) |
| PT (1) | PT3548026T (enExample) |
| SI (1) | SI3548026T1 (enExample) |
| WO (1) | WO2018100557A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3548026T (lt) | 2016-12-01 | 2021-05-25 | Minoryx Therapeutics S.L. | 5-[[4-[2-[5-(1-hidroksietil)piridin-2-il]etoksi]fenil]metil]-1,3-tiazolidin-2,4-dionas nealkoholinio kepenų suriebėjimo gydymui |
| PL3801515T3 (pl) | 2018-06-06 | 2025-07-14 | Minoryx Therapeutics S.L. | 5-[[4-[2-[5-(1-hydroksyetylo)pirydyn-2-ylo]etoksy]fenylo]metylo]-1,3-tiazolidyno-2,4-dion i jego sole do zastosowania w leczeniu chorób mitochondrialnych |
| KR20230035522A (ko) | 2020-04-30 | 2023-03-14 | 미노릭스 테라퓨틱스 에스.엘. | 폐 염증 및 간질성 폐 질병을 치료하기 위한 레리글리타존 |
| WO2024141951A1 (en) | 2022-12-28 | 2024-07-04 | Minoryx Therapeutics S.L. | Optimized dosing of leriglitazone |
| AU2024268104A1 (en) | 2023-05-09 | 2025-11-27 | Minoryx Therapeutics S.L. | Polymorphic forms and formulations of leriglitazone |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5441971A (en) | 1991-04-11 | 1995-08-15 | The Upjohn Company | Thiazolidinedione derivatives, production and use thereof |
| SK109993A3 (en) | 1991-04-11 | 1994-12-07 | Upjohn Co | Thiazolidinedione derivatives producing and use thereof |
| WO1993022445A1 (en) | 1992-05-05 | 1993-11-11 | The Upjohn Company | A process for producing pioglitazone metabolite |
| US5952509A (en) | 1996-06-27 | 1999-09-14 | Takeda Chemical Industries, Ltd. | Production of benzaldehyde compounds |
| US6191154B1 (en) | 1998-11-27 | 2001-02-20 | Case Western Reserve University | Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases |
| US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6720001B2 (en) | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
| US20050107450A1 (en) | 2001-12-21 | 2005-05-19 | Brown Kathleen K. | Dosing regimen for ppar-gamma activators |
| US8993773B2 (en) | 2002-07-16 | 2015-03-31 | Cadila Healthcare Limited | Process to prepare pioglitazone via several novel intermediates |
| GB0510469D0 (en) | 2005-05-23 | 2005-06-29 | Leuven K U Res & Dev | Insulin sensitization to slow down pubertal tempo and to augment pubertal growth |
| MX356584B (es) | 2006-03-16 | 2018-06-05 | Metabolic Solutions Dev Co | Analogos de tiazolidindiona para el tratamiento de enfermedad mediada por inflamacion metabolica. |
| US8722710B2 (en) | 2007-09-26 | 2014-05-13 | Deuterx, Llc | Deuterium-enriched pioglitazone |
| US8895536B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating chronic inflammation and inflammatory diseases |
| WO2013040419A1 (en) | 2011-09-14 | 2013-03-21 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for treating hyperprolinemia-associated mental disorders |
| US8865747B2 (en) | 2012-03-23 | 2014-10-21 | Fundació Institute D'Investigació Biomėdica de Bellvitge (IDIBELL) | Pioglitazone for use in the treatment of adrenoleukodystrophy |
| US20140178456A1 (en) | 2012-08-30 | 2014-06-26 | Udaya Sankar Devanaboyina | Methods and compositions for treating type 2 diabetes and related conditions |
| US8969581B2 (en) | 2013-03-14 | 2015-03-03 | Deuterx, Llc | 5-deutero-2,4-thiazolidinedione derivatives and compositions comprising and methods of using the same |
| WO2015109037A1 (en) | 2014-01-15 | 2015-07-23 | Deuterx, Llc | Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone |
| ES2678046T3 (es) | 2014-04-02 | 2018-08-08 | Minoryx Therapeutics S.L. | Derivados de 2,4-tiazolidindiona en el tratamiento de trastornos del sistema nervioso central |
| LT3548026T (lt) | 2016-12-01 | 2021-05-25 | Minoryx Therapeutics S.L. | 5-[[4-[2-[5-(1-hidroksietil)piridin-2-il]etoksi]fenil]metil]-1,3-tiazolidin-2,4-dionas nealkoholinio kepenų suriebėjimo gydymui |
-
2017
- 2017-12-01 LT LTEP17817175.7T patent/LT3548026T/lt unknown
- 2017-12-01 SI SI201730714T patent/SI3548026T1/sl unknown
- 2017-12-01 HR HRP20210576TT patent/HRP20210576T1/hr unknown
- 2017-12-01 CN CN201780074388.1A patent/CN110022877B/zh active Active
- 2017-12-01 AU AU2017370003A patent/AU2017370003B2/en not_active Ceased
- 2017-12-01 BR BR112019011334A patent/BR112019011334A2/pt not_active Application Discontinuation
- 2017-12-01 HU HUE17817175A patent/HUE054346T2/hu unknown
- 2017-12-01 KR KR1020197019093A patent/KR102595034B1/ko active Active
- 2017-12-01 US US16/465,043 patent/US11938122B2/en active Active
- 2017-12-01 PT PT178171757T patent/PT3548026T/pt unknown
- 2017-12-01 EA EA201991304A patent/EA201991304A1/ru unknown
- 2017-12-01 CA CA3044364A patent/CA3044364A1/en active Pending
- 2017-12-01 ES ES17817175T patent/ES2867300T3/es active Active
- 2017-12-01 PL PL17817175T patent/PL3548026T3/pl unknown
- 2017-12-01 WO PCT/IB2017/057587 patent/WO2018100557A1/en not_active Ceased
- 2017-12-01 EP EP17817175.7A patent/EP3548026B1/en active Active
- 2017-12-01 JP JP2019529165A patent/JP7040798B2/ja not_active Expired - Fee Related
- 2017-12-01 DK DK17817175.7T patent/DK3548026T3/da active
- 2017-12-01 MX MX2019006066A patent/MX379710B/es unknown
-
2021
- 2021-04-16 CY CY20211100335T patent/CY1124116T1/el unknown
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