JP2020500152A - 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法 - Google Patents

抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法 Download PDF

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JP2020500152A
JP2020500152A JP2019517351A JP2019517351A JP2020500152A JP 2020500152 A JP2020500152 A JP 2020500152A JP 2019517351 A JP2019517351 A JP 2019517351A JP 2019517351 A JP2019517351 A JP 2019517351A JP 2020500152 A JP2020500152 A JP 2020500152A
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antibody
weeks
patient
guselkumab
amino acid
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JP2020500152A5 (enExample
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ランダッゾ，ブルース
ワスフィ，ヤスミン
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ヤンセン バイオテツク，インコーポレーテツド
ヤンセン バイオテツク，インコーポレーテツド
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Publication of JP2020500152A publication Critical patent/JP2020500152A/ja
Publication of JP2020500152A5 publication Critical patent/JP2020500152A5/ja
Priority to JP2022026794A priority Critical patent/JP2022071020A/ja
Priority to JP2024053862A priority patent/JP2024088688A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2019517351A 2016-09-30 2017-09-29 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法 Withdrawn JP2020500152A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022026794A JP2022071020A (ja) 2016-09-30 2022-02-24 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法
JP2024053862A JP2024088688A (ja) 2016-09-30 2024-03-28 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662402403P 2016-09-30 2016-09-30
US62/402,403 2016-09-30
US201762532068P 2017-07-13 2017-07-13
US62/532,068 2017-07-13
PCT/US2017/054217 WO2018064436A1 (en) 2016-09-30 2017-09-29 Safe and effective method of treating psoriasis with anti-il23 specific antibody

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JP2022026794A Division JP2022071020A (ja) 2016-09-30 2022-02-24 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法

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JP2020500152A true JP2020500152A (ja) 2020-01-09
JP2020500152A5 JP2020500152A5 (enExample) 2020-11-12

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JP2019517351A Withdrawn JP2020500152A (ja) 2016-09-30 2017-09-29 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法
JP2022026794A Withdrawn JP2022071020A (ja) 2016-09-30 2022-02-24 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法
JP2024053862A Pending JP2024088688A (ja) 2016-09-30 2024-03-28 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法

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JP2022026794A Withdrawn JP2022071020A (ja) 2016-09-30 2022-02-24 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法
JP2024053862A Pending JP2024088688A (ja) 2016-09-30 2024-03-28 抗ｉｌ２３特異的抗体で乾癬を治療する安全かつ有効な方法

Country Status (10)

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US (3) US20180094052A1 (enExample)
EP (1) EP3519049B1 (enExample)
JP (3) JP2020500152A (enExample)
KR (2) KR20240046648A (enExample)
AU (2) AU2017336799B2 (enExample)
CA (1) CA3037961A1 (enExample)
IL (3) IL316408A (enExample)
MA (1) MA46366A (enExample)
MX (1) MX2019003703A (enExample)
WO (1) WO2018064436A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023528265A (ja) * 2020-05-21 2023-07-04 ヤンセン バイオテツク，インコーポレーテツド Ｉｌ－２３に対する抗体及びｔｎｆアルファに対する抗体の組み合わせ療法を用いた炎症性腸疾患の治療方法

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MX2020004716A (es) 2017-11-06 2020-11-06 Janssen Biotech Inc Método seguro y eficaz para tratar la artritis psoriásica con el anticuerpo específico anti-il23.
US20190269757A1 (en) 2018-03-05 2019-09-05 Janssen Biotech, Inc. Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody
JP2021523138A (ja) * 2018-05-11 2021-09-02 ヤンセン バイオテツク，インコーポレーテツド Ｉｌ−２３抗体を使用してうつを治療する方法
WO2020016838A2 (en) * 2018-07-18 2020-01-23 Janssen Biotech, Inc. Sustained response predictors after treatment with anti-il23 specific antibody
BR112021009287A2 (pt) * 2018-11-20 2021-10-26 Janssen Biotech, Inc. Método seguro e eficaz para tratar psoríase com anticorpo específico anti-il-23
IL297363A (en) * 2020-04-20 2022-12-01 Edesa Biotech Res Inc Compositions and methods for treatment of acute respiratory distress syndrome
CN115515634A (zh) * 2020-05-05 2022-12-23 詹森生物科技公司 用抗il23特异性抗体治疗克罗恩病的方法
WO2022013745A1 (en) * 2020-07-13 2022-01-20 Janssen Biotech, Inc. Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody
CN117751138A (zh) * 2021-03-12 2024-03-22 詹森生物科技公司 用抗il23特异性抗体治疗银屑病关节炎的安全且有效的方法
KR20240012469A (ko) 2021-05-20 2024-01-29 얀센 바이오테크 인코포레이티드 Il-23 및 tnf 알파에 대한 항체의 병용요법으로 염증성 장질환을 치료하는 방법
CA3242957A1 (en) * 2021-12-17 2025-02-26 Janssen Biotech, Inc. Specific IL-23 antibodies for the treatment of systemic sclerosis
TW202448936A (zh) 2023-05-03 2024-12-16 美商健生生物科技公司 以針對ＩＬ－２３及ＴＮＦ α的抗體的組合來治療潰瘍性結腸炎之方法
TW202508626A (zh) 2023-05-03 2025-03-01 美商健生生物科技公司 以針對ＩＬ－２３及ＴＮＦα的抗體的組合來治療克隆氏症之方法

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