JP2020182486A5 - - Google Patents
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- Publication number
- JP2020182486A5 JP2020182486A5 JP2020123157A JP2020123157A JP2020182486A5 JP 2020182486 A5 JP2020182486 A5 JP 2020182486A5 JP 2020123157 A JP2020123157 A JP 2020123157A JP 2020123157 A JP2020123157 A JP 2020123157A JP 2020182486 A5 JP2020182486 A5 JP 2020182486A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- conjugation
- subject
- cell
- molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 50
- 102000036639 antigens Human genes 0.000 claims 50
- 108091007433 antigens Proteins 0.000 claims 50
- 210000004027 cell Anatomy 0.000 claims 32
- 239000003504 photosensitizing agent Substances 0.000 claims 27
- 230000021615 conjugation Effects 0.000 claims 25
- 108090000695 Cytokines Proteins 0.000 claims 24
- 102000004127 Cytokines Human genes 0.000 claims 24
- 238000000034 method Methods 0.000 claims 19
- 230000028993 immune response Effects 0.000 claims 18
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 9
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 7
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 201000011510 cancer Diseases 0.000 claims 6
- PBHVCRIXMXQXPD-UHFFFAOYSA-N chembl2369102 Chemical compound C1=CC(S(=O)(=O)O)=CC=C1C(C1=CC=C(N1)C(C=1C=CC(=CC=1)S(O)(=O)=O)=C1C=CC(=N1)C(C=1C=CC(=CC=1)S(O)(=O)=O)=C1C=CC(N1)=C1C=2C=CC(=CC=2)S(O)(=O)=O)=C2N=C1C=C2 PBHVCRIXMXQXPD-UHFFFAOYSA-N 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 229960005486 vaccine Drugs 0.000 claims 6
- 229940124856 vaccine component Drugs 0.000 claims 6
- 101100537798 Arabidopsis thaliana TPS11 gene Proteins 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 5
- 208000035475 disorder Diseases 0.000 claims 5
- 208000015181 infectious disease Diseases 0.000 claims 5
- 238000002255 vaccination Methods 0.000 claims 5
- 229940079593 drug Drugs 0.000 claims 4
- 239000003085 diluting agent Substances 0.000 claims 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 239000000825 pharmaceutical preparation Substances 0.000 claims 3
- 229940127557 pharmaceutical product Drugs 0.000 claims 3
- 230000004936 stimulating effect Effects 0.000 claims 3
- 239000000969 carrier Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229920001661 Chitosan Polymers 0.000 claims 1
- 230000030741 antigen processing and presentation Effects 0.000 claims 1
- 230000000890 antigenic effect Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000000172 cytosol Anatomy 0.000 claims 1
- 210000004443 dendritic cell Anatomy 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000001678 irradiating effect Effects 0.000 claims 1
- 210000004698 lymphocyte Anatomy 0.000 claims 1
- 210000002540 macrophage Anatomy 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000000638 stimulation Effects 0.000 claims 1
- AVWQQPYHYQKEIZ-UHFFFAOYSA-K trisodium;2-dodecylbenzenesulfonate;3-dodecylbenzenesulfonate;4-dodecylbenzenesulfonate Chemical compound [Na+].[Na+].[Na+].CCCCCCCCCCCCC1=CC=C(S([O-])(=O)=O)C=C1.CCCCCCCCCCCCC1=CC=CC(S([O-])(=O)=O)=C1.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O AVWQQPYHYQKEIZ-UHFFFAOYSA-K 0.000 claims 1
- 0 CCC(CO[C@@](C)[C@](C1O)NC(C*(C)(C)C)=O)[C@@]1(*)O[C@@](C)(C(C1O)N(C)C(CN2CCN(CC(Nc(cc3)ccc3C(C(C=C3)=NC3=C(C3=CC[C@](C(c4ccccc4)=C4N=C5C=C4)N3)c3ccccc3)=C(C=C3)NC3=C5c3ccccc3)=O)CC2)=O)OC(CO)[C@]1ON Chemical compound CCC(CO[C@@](C)[C@](C1O)NC(C*(C)(C)C)=O)[C@@]1(*)O[C@@](C)(C(C1O)N(C)C(CN2CCN(CC(Nc(cc3)ccc3C(C(C=C3)=NC3=C(C3=CC[C@](C(c4ccccc4)=C4N=C5C=C4)N3)c3ccccc3)=C(C=C3)NC3=C5c3ccccc3)=O)CC2)=O)OC(CO)[C@]1ON 0.000 description 5
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201415247A GB201415247D0 (en) | 2014-08-28 | 2014-08-28 | Compound and method |
| GB1415247.4 | 2014-08-28 | ||
| GB1420773.2 | 2014-11-21 | ||
| GB201420773A GB201420773D0 (en) | 2014-11-21 | 2014-11-21 | Compound and method |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017511702A Division JP2017526371A (ja) | 2014-08-28 | 2015-08-28 | 化合物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020182486A JP2020182486A (ja) | 2020-11-12 |
| JP2020182486A5 true JP2020182486A5 (cg-RX-API-DMAC7.html) | 2021-04-15 |
| JP7079819B2 JP7079819B2 (ja) | 2022-06-02 |
Family
ID=54065872
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017511702A Pending JP2017526371A (ja) | 2014-08-28 | 2015-08-28 | 化合物および方法 |
| JP2020123157A Active JP7079819B2 (ja) | 2014-08-28 | 2020-07-17 | 化合物および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017511702A Pending JP2017526371A (ja) | 2014-08-28 | 2015-08-28 | 化合物および方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10537639B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3185901B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2017526371A (cg-RX-API-DMAC7.html) |
| KR (1) | KR102678732B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN108136016A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015308345B9 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112017003486A2 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ729408A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016030529A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109912607B (zh) * | 2018-12-11 | 2021-01-22 | 南华大学 | 一类卟啉-白杨素复合物及其抗肿瘤活性 |
| JP7288951B2 (ja) | 2019-02-19 | 2023-06-08 | 大塚電子株式会社 | 光線力学的療法条件パラメータの決定方法および光線力学的療法装置 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO180167C (no) | 1994-09-08 | 1997-02-26 | Photocure As | Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol |
| GB9905911D0 (en) | 1999-03-15 | 1999-05-05 | Photocure As | Method |
| CA2430087C (en) | 2000-11-29 | 2016-06-28 | Pci Biotech As | Photochemical internalization for delivery of molecules into the cytosol |
| AU3069302A (en) | 2000-12-13 | 2002-06-24 | Immunex Corp | Method for generating immortal dendritic cell lines |
| GB0121023D0 (en) | 2001-08-30 | 2001-10-24 | Norwegian Radium Hospital Res | Compound |
| AU2004289368B2 (en) | 2003-11-12 | 2010-08-26 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Custom vectors for treating and preventing pancreatic cancer |
| WO2005097976A1 (ja) | 2004-04-06 | 2005-10-20 | Ehime University | 抗原パルスして得られた樹状細胞 |
| WO2005100547A1 (ja) * | 2004-04-06 | 2005-10-27 | Techno Network Shikoku Co., Ltd. | 抗原パルスして得られた樹状細胞 |
| CN102099054A (zh) * | 2008-06-06 | 2011-06-15 | 贝勒研究院 | 呼吸道合胞病毒呈递树突细胞致耐受性 |
| EP2456787A4 (en) | 2009-07-24 | 2013-01-30 | Univ Leland Stanford Junior | CYTOKIN COMPOSITIONS AND METHOD FOR THEIR USE |
| GB201208548D0 (en) * | 2012-05-15 | 2012-06-27 | Pci Biotech As | Compound and method |
| WO2014139597A1 (en) | 2013-03-15 | 2014-09-18 | Pci Biotech As | Method |
| WO2015028575A1 (en) | 2013-08-28 | 2015-03-05 | Pci Biotech As | Immunisation method by photochemical internalisation |
| AU2014314149B2 (en) | 2013-08-28 | 2019-12-19 | Pci Biotech As | Compound and method for vaccination and immunisation |
| AU2014390262B2 (en) | 2014-04-11 | 2020-11-26 | Pci Biotech As | Method of treating melanoma |
-
2015
- 2015-08-28 CN CN201580055883.9A patent/CN108136016A/zh active Pending
- 2015-08-28 KR KR1020177008280A patent/KR102678732B1/ko active Active
- 2015-08-28 US US15/506,453 patent/US10537639B2/en active Active
- 2015-08-28 JP JP2017511702A patent/JP2017526371A/ja active Pending
- 2015-08-28 BR BR112017003486A patent/BR112017003486A2/pt active Search and Examination
- 2015-08-28 AU AU2015308345A patent/AU2015308345B9/en active Active
- 2015-08-28 WO PCT/EP2015/069794 patent/WO2016030529A1/en not_active Ceased
- 2015-08-28 EP EP15760426.5A patent/EP3185901B1/en active Active
- 2015-08-28 NZ NZ729408A patent/NZ729408A/en unknown
-
2020
- 2020-07-17 JP JP2020123157A patent/JP7079819B2/ja active Active
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