JP2020120689A5 - - Google Patents
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- JP2020120689A5 JP2020120689A5 JP2020085079A JP2020085079A JP2020120689A5 JP 2020120689 A5 JP2020120689 A5 JP 2020120689A5 JP 2020085079 A JP2020085079 A JP 2020085079A JP 2020085079 A JP2020085079 A JP 2020085079A JP 2020120689 A5 JP2020120689 A5 JP 2020120689A5
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- Prior art keywords
- seq
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- heavy chain
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- 239000012634 fragment Substances 0.000 claims 27
- 239000000427 antigen Substances 0.000 claims 24
- 102000036639 antigens Human genes 0.000 claims 24
- 108091007433 antigens Proteins 0.000 claims 24
- 239000000203 mixture Substances 0.000 claims 9
- 241000725303 Human immunodeficiency virus Species 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 6
- 238000012986 modification Methods 0.000 claims 6
- 230000004048 modification Effects 0.000 claims 6
- 229920001184 polypeptide Polymers 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 229940124597 therapeutic agent Drugs 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 5
- NFGXHKASABOEEW-UHFFFAOYSA-N 1-methylethyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate Chemical compound COC(C)(C)CCCC(C)CC=CC(C)=CC(=O)OC(C)C NFGXHKASABOEEW-UHFFFAOYSA-N 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 3
- 239000002259 anti human immunodeficiency virus agent Substances 0.000 claims 3
- 229940124411 anti-hiv antiviral agent Drugs 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 229940044616 toll-like receptor 7 agonist Drugs 0.000 claims 3
- JKGGPMOUIAAJAA-YEPSODPASA-N Thr-Gly-Val Chemical compound [H]N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](C(C)C)C(O)=O JKGGPMOUIAAJAA-YEPSODPASA-N 0.000 claims 2
- 241000024188 Andala Species 0.000 claims 1
- VGQVAVQWKJLIRM-FXQIFTODSA-N Ser-Ser-Val Chemical compound [H]N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(O)=O VGQVAVQWKJLIRM-FXQIFTODSA-N 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 210000005253 yeast cell Anatomy 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021137876A JP7126594B2 (ja) | 2015-12-15 | 2021-08-26 | ヒト免疫不全ウイルス中和抗体 |
| JP2022129584A JP2022163192A (ja) | 2015-12-15 | 2022-08-16 | ヒト免疫不全ウイルス中和抗体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562267652P | 2015-12-15 | 2015-12-15 | |
| US62/267,652 | 2015-12-15 | ||
| JP2018530831A JP6732915B2 (ja) | 2015-12-15 | 2016-12-14 | ヒト免疫不全ウイルス中和抗体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018530831A Division JP6732915B2 (ja) | 2015-12-15 | 2016-12-14 | ヒト免疫不全ウイルス中和抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021137876A Division JP7126594B2 (ja) | 2015-12-15 | 2021-08-26 | ヒト免疫不全ウイルス中和抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020120689A JP2020120689A (ja) | 2020-08-13 |
| JP2020120689A5 true JP2020120689A5 (enExample) | 2020-11-12 |
| JP6936361B2 JP6936361B2 (ja) | 2021-09-15 |
Family
ID=58737847
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018530831A Active JP6732915B2 (ja) | 2015-12-15 | 2016-12-14 | ヒト免疫不全ウイルス中和抗体 |
| JP2020085079A Active JP6936361B2 (ja) | 2015-12-15 | 2020-05-14 | ヒト免疫不全ウイルス中和抗体 |
| JP2021137876A Active JP7126594B2 (ja) | 2015-12-15 | 2021-08-26 | ヒト免疫不全ウイルス中和抗体 |
| JP2022129584A Withdrawn JP2022163192A (ja) | 2015-12-15 | 2022-08-16 | ヒト免疫不全ウイルス中和抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018530831A Active JP6732915B2 (ja) | 2015-12-15 | 2016-12-14 | ヒト免疫不全ウイルス中和抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021137876A Active JP7126594B2 (ja) | 2015-12-15 | 2021-08-26 | ヒト免疫不全ウイルス中和抗体 |
| JP2022129584A Withdrawn JP2022163192A (ja) | 2015-12-15 | 2022-08-16 | ヒト免疫不全ウイルス中和抗体 |
Country Status (37)
Families Citing this family (61)
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