JP2020023491A5 - - Google Patents
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- JP2020023491A5 JP2020023491A5 JP2019163497A JP2019163497A JP2020023491A5 JP 2020023491 A5 JP2020023491 A5 JP 2020023491A5 JP 2019163497 A JP2019163497 A JP 2019163497A JP 2019163497 A JP2019163497 A JP 2019163497A JP 2020023491 A5 JP2020023491 A5 JP 2020023491A5
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- 241000125945 Protoparvovirus Species 0.000 claims description 8
- 239000012528 membrane Substances 0.000 claims description 8
- 238000011045 prefiltration Methods 0.000 claims description 7
- 238000005341 cation exchange Methods 0.000 claims description 5
- 238000011100 viral filtration Methods 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 13
- 241000700605 Viruses Species 0.000 claims 9
- 239000002594 sorbent Substances 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 229940126622 therapeutic monoclonal antibody Drugs 0.000 claims 5
- -1 CD11a Proteins 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 238000011013 endotoxin removal Methods 0.000 claims 3
- 238000001914 filtration Methods 0.000 claims 3
- 239000011148 porous material Substances 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 2
- 238000001742 protein purification Methods 0.000 claims 2
- 108020003175 receptors Proteins 0.000 claims 2
- 102000005962 receptors Human genes 0.000 claims 2
- 101100067974 Arabidopsis thaliana POP2 gene Proteins 0.000 claims 1
- 102100038080 B-cell receptor CD22 Human genes 0.000 claims 1
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 claims 1
- 101150013553 CD40 gene Proteins 0.000 claims 1
- 241000699802 Cricetulus griseus Species 0.000 claims 1
- 102000001301 EGF receptor Human genes 0.000 claims 1
- 102100032031 Epidermal growth factor-like protein 7 Human genes 0.000 claims 1
- 101000884305 Homo sapiens B-cell receptor CD22 Proteins 0.000 claims 1
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 claims 1
- 101100118549 Homo sapiens EGFR gene Proteins 0.000 claims 1
- 101000921195 Homo sapiens Epidermal growth factor-like protein 7 Proteins 0.000 claims 1
- 101001046686 Homo sapiens Integrin alpha-M Proteins 0.000 claims 1
- 101000935040 Homo sapiens Integrin beta-2 Proteins 0.000 claims 1
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 claims 1
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 1
- 101100369992 Homo sapiens TNFSF10 gene Proteins 0.000 claims 1
- 102100022338 Integrin alpha-M Human genes 0.000 claims 1
- 102100022297 Integrin alpha-X Human genes 0.000 claims 1
- 108010008212 Integrin alpha4beta1 Proteins 0.000 claims 1
- 102100025390 Integrin beta-2 Human genes 0.000 claims 1
- 102000013691 Interleukin-17 Human genes 0.000 claims 1
- 108050003558 Interleukin-17 Proteins 0.000 claims 1
- 108090000772 Neuropilin-1 Proteins 0.000 claims 1
- 102000001253 Protein Kinase Human genes 0.000 claims 1
- 102100023068 Protein kinase C-binding protein NELL1 Human genes 0.000 claims 1
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 claims 1
- 102100029986 Receptor tyrosine-protein kinase erbB-3 Human genes 0.000 claims 1
- 101710100969 Receptor tyrosine-protein kinase erbB-3 Proteins 0.000 claims 1
- 102100029981 Receptor tyrosine-protein kinase erbB-4 Human genes 0.000 claims 1
- 101710100963 Receptor tyrosine-protein kinase erbB-4 Proteins 0.000 claims 1
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 1
- 201000000582 Retinoblastoma Diseases 0.000 claims 1
- 101100123851 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) HER1 gene Proteins 0.000 claims 1
- 102000046283 TNF-Related Apoptosis-Inducing Ligand Human genes 0.000 claims 1
- 108700012411 TNFSF10 Proteins 0.000 claims 1
- 102100022563 Tubulin polymerization-promoting protein Human genes 0.000 claims 1
- 102100040245 Tumor necrosis factor receptor superfamily member 5 Human genes 0.000 claims 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 1
- 230000002494 anti-cea effect Effects 0.000 claims 1
- 229940046836 anti-estrogen Drugs 0.000 claims 1
- 230000001833 anti-estrogenic effect Effects 0.000 claims 1
- 239000003418 antiprogestin Substances 0.000 claims 1
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 claims 1
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 claims 1
- 239000000328 estrogen antagonist Substances 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 238000004255 ion exchange chromatography Methods 0.000 claims 1
- 230000011278 mitosis Effects 0.000 claims 1
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 claims 1
- 102000027450 oncoproteins Human genes 0.000 claims 1
- 108091008819 oncoproteins Proteins 0.000 claims 1
- 210000001672 ovary Anatomy 0.000 claims 1
- 230000003623 progesteronic effect Effects 0.000 claims 1
- 108060006633 protein kinase Proteins 0.000 claims 1
- 239000003463 adsorbent Substances 0.000 description 2
- 239000000356 contaminant Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022185354A JP2023029853A (ja) | 2009-08-06 | 2022-11-21 | タンパク質精製におけるウイルス除去の改良方法 |
| JP2024159627A JP2025003999A (ja) | 2009-08-06 | 2024-09-13 | タンパク質精製におけるウイルス除去の改良方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23181109P | 2009-08-06 | 2009-08-06 | |
| US61/231,811 | 2009-08-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017121588A Division JP2017206529A (ja) | 2009-08-06 | 2017-06-21 | タンパク質精製におけるウイルス除去の改良方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022185354A Division JP2023029853A (ja) | 2009-08-06 | 2022-11-21 | タンパク質精製におけるウイルス除去の改良方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020023491A JP2020023491A (ja) | 2020-02-13 |
| JP2020023491A5 true JP2020023491A5 (enExample) | 2022-12-08 |
Family
ID=42985499
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523983A Withdrawn JP2013501075A (ja) | 2009-08-06 | 2010-08-06 | タンパク質精製におけるウイルス除去の改良方法 |
| JP2015252787A Pending JP2016106096A (ja) | 2009-08-06 | 2015-12-25 | タンパク質精製におけるウイルス除去の改良方法 |
| JP2017121588A Pending JP2017206529A (ja) | 2009-08-06 | 2017-06-21 | タンパク質精製におけるウイルス除去の改良方法 |
| JP2019163497A Withdrawn JP2020023491A (ja) | 2009-08-06 | 2019-09-09 | タンパク質精製におけるウイルス除去の改良方法 |
| JP2022185354A Withdrawn JP2023029853A (ja) | 2009-08-06 | 2022-11-21 | タンパク質精製におけるウイルス除去の改良方法 |
| JP2024159627A Pending JP2025003999A (ja) | 2009-08-06 | 2024-09-13 | タンパク質精製におけるウイルス除去の改良方法 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523983A Withdrawn JP2013501075A (ja) | 2009-08-06 | 2010-08-06 | タンパク質精製におけるウイルス除去の改良方法 |
| JP2015252787A Pending JP2016106096A (ja) | 2009-08-06 | 2015-12-25 | タンパク質精製におけるウイルス除去の改良方法 |
| JP2017121588A Pending JP2017206529A (ja) | 2009-08-06 | 2017-06-21 | タンパク質精製におけるウイルス除去の改良方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022185354A Withdrawn JP2023029853A (ja) | 2009-08-06 | 2022-11-21 | タンパク質精製におけるウイルス除去の改良方法 |
| JP2024159627A Pending JP2025003999A (ja) | 2009-08-06 | 2024-09-13 | タンパク質精製におけるウイルス除去の改良方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (5) | US10662237B2 (enExample) |
| EP (3) | EP4559926A3 (enExample) |
| JP (6) | JP2013501075A (enExample) |
| KR (3) | KR20180035936A (enExample) |
| CN (2) | CN102712691A (enExample) |
| AU (1) | AU2010292897B2 (enExample) |
| BR (1) | BR112012002574A2 (enExample) |
| CA (1) | CA2770235C (enExample) |
| DK (1) | DK2462158T3 (enExample) |
| ES (1) | ES2662529T3 (enExample) |
| HR (1) | HRP20180309T1 (enExample) |
| HU (1) | HUE038451T2 (enExample) |
| IL (3) | IL217740B (enExample) |
| LT (1) | LT2462158T (enExample) |
| MX (1) | MX346115B (enExample) |
| MY (1) | MY188566A (enExample) |
| NO (1) | NO2462158T3 (enExample) |
| NZ (1) | NZ597809A (enExample) |
| PL (1) | PL2462158T3 (enExample) |
| PT (1) | PT2462158T (enExample) |
| RU (1) | RU2573894C2 (enExample) |
| SG (1) | SG178276A1 (enExample) |
| SI (1) | SI2462158T1 (enExample) |
| WO (1) | WO2011031397A1 (enExample) |
| ZA (1) | ZA201200626B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2527425A1 (en) | 2006-09-13 | 2012-11-28 | Abbott Laboratories | Cell culture improvements |
| US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
| TW201024318A (en) | 2008-10-20 | 2010-07-01 | Abbott Lab | Isolation and purification of antibodies using protein A affinity chromatography |
| NZ592097A (en) | 2008-10-20 | 2013-01-25 | Abbott Lab | Viral inactivation during purification of il-12 and il-18 antibodies |
| NO2462158T3 (enExample) | 2009-08-06 | 2018-06-09 | ||
| TW201302793A (zh) | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 |
| CA2830640A1 (en) * | 2011-03-25 | 2012-10-04 | Genentech, Inc. | Novel protein purification methods |
| DE102011105525B4 (de) | 2011-06-24 | 2015-03-26 | Sartorius Stedim Biotech Gmbh | Verfahren zur Abtrennung von Biopolymer-Aggregaten und Viren aus einem Fluid |
| WO2013028330A2 (en) | 2011-08-19 | 2013-02-28 | Emd Millipore Corporation | Methods of reducing level of one of more impurities in a sample during protein purification |
| HRP20181846T1 (hr) | 2011-12-22 | 2018-12-28 | Genentech, Inc. | Kromatografija membranom za ionsku izmjenu |
| KR102260855B1 (ko) | 2013-09-13 | 2021-06-04 | 제넨테크, 인크. | 세포주에서 숙주 세포 단백질 및 재조합 폴리펩티드 생성물을 검출 및 정량화하기 위한 조성물 및 방법 |
| NZ756749A (en) | 2013-09-13 | 2022-05-27 | Genentech Inc | Methods and compositions comprising purified recombinant polypeptides |
| AU2015334455B2 (en) * | 2014-10-21 | 2020-05-21 | Gennova Biopharmaceuticals Limited | A novel purification process for isolation and commercial production of recombinant TNK-tPA (Tenecteplase) |
| EP3274359B1 (en) * | 2015-03-23 | 2022-11-02 | Alexion Pharmaceuticals, Inc. | Virus filtration |
| EP3639911B1 (en) * | 2017-06-12 | 2024-07-31 | Asahi Kasei Medical Co., Ltd. | Filtration method for protein-containing liquid |
| KR102753090B1 (ko) * | 2017-12-21 | 2025-01-14 | 젠자임 코포레이션 | 단백질 a 크로마토그래피 동안 불순물의 향상된 제거를 위한 방법 |
| TWI871300B (zh) * | 2019-01-28 | 2025-02-01 | 美商安進公司 | 藉由將藥物物質和藥物產品過程整體化的生物製劑製造之連續製造過程 |
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| NO2462158T3 (enExample) | 2009-08-06 | 2018-06-09 | ||
| CN108409829A (zh) | 2009-09-01 | 2018-08-17 | 弗·哈夫曼-拉罗切有限公司 | 通过改进的a蛋白洗脱增强的蛋白质纯化 |
-
2010
- 2010-08-06 NO NO10740823A patent/NO2462158T3/no unknown
- 2010-08-06 HU HUE10740823A patent/HUE038451T2/hu unknown
- 2010-08-06 WO PCT/US2010/044760 patent/WO2011031397A1/en not_active Ceased
- 2010-08-06 SI SI201031646T patent/SI2462158T1/en unknown
- 2010-08-06 CN CN2010800447903A patent/CN102712691A/zh active Pending
- 2010-08-06 EP EP24217316.9A patent/EP4559926A3/en active Pending
- 2010-08-06 RU RU2012108318/10A patent/RU2573894C2/ru active
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