JP2020012000A5 - - Google Patents
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- JP2020012000A5 JP2020012000A5 JP2019194124A JP2019194124A JP2020012000A5 JP 2020012000 A5 JP2020012000 A5 JP 2020012000A5 JP 2019194124 A JP2019194124 A JP 2019194124A JP 2019194124 A JP2019194124 A JP 2019194124A JP 2020012000 A5 JP2020012000 A5 JP 2020012000A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- composition according
- chimeric receptor
- pharmaceutical composition
- mesocerine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000203 mixture Substances 0.000 claims 14
- 108700010039 chimeric receptor Proteins 0.000 claims 12
- 239000000427 antigen Substances 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 230000003834 intracellular effect Effects 0.000 claims 8
- 206010028980 Neoplasm Diseases 0.000 claims 7
- 108020004999 messenger RNA Proteins 0.000 claims 6
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims 4
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims 4
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 claims 4
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 claims 4
- 101000914514 Homo sapiens T-cell-specific surface glycoprotein CD28 Proteins 0.000 claims 4
- 208000025205 Mantle-Cell Lymphoma Diseases 0.000 claims 4
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 claims 4
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims 4
- 102100027213 T-cell-specific surface glycoprotein CD28 Human genes 0.000 claims 4
- 208000032852 chronic lymphocytic leukemia Diseases 0.000 claims 4
- 210000005105 peripheral blood lymphocyte Anatomy 0.000 claims 4
- 230000011664 signaling Effects 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 3
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 2
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 2
- 206010005003 Bladder cancer Diseases 0.000 claims 2
- 206010005949 Bone cancer Diseases 0.000 claims 2
- 208000018084 Bone neoplasm Diseases 0.000 claims 2
- 208000003174 Brain Neoplasms Diseases 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 206010008342 Cervix carcinoma Diseases 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 2
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 206010038389 Renal cancer Diseases 0.000 claims 2
- 208000000453 Skin Neoplasms Diseases 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- 208000024313 Testicular Neoplasms Diseases 0.000 claims 2
- 206010057644 Testis cancer Diseases 0.000 claims 2
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 2
- 208000002495 Uterine Neoplasms Diseases 0.000 claims 2
- 201000010881 cervical cancer Diseases 0.000 claims 2
- 208000029742 colonic neoplasm Diseases 0.000 claims 2
- 201000004101 esophageal cancer Diseases 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 201000010536 head and neck cancer Diseases 0.000 claims 2
- 208000014829 head and neck neoplasm Diseases 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 201000010982 kidney cancer Diseases 0.000 claims 2
- 208000032839 leukemia Diseases 0.000 claims 2
- 201000007270 liver cancer Diseases 0.000 claims 2
- 208000014018 liver neoplasm Diseases 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 230000000527 lymphocytic effect Effects 0.000 claims 2
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 2
- 210000005087 mononuclear cell Anatomy 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- 201000002528 pancreatic cancer Diseases 0.000 claims 2
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 2
- 201000000849 skin cancer Diseases 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 201000003120 testicular cancer Diseases 0.000 claims 2
- 201000005112 urinary bladder cancer Diseases 0.000 claims 2
- 206010046766 uterine cancer Diseases 0.000 claims 2
- 230000000139 costimulatory effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4365308P | 2008-04-09 | 2008-04-09 | |
| US61/043,653 | 2008-04-09 | ||
| JP2017131791A JP2017184759A (ja) | 2008-04-09 | 2017-07-05 | 新規に単離された細胞の治療組成物の操作および送達 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017131791A Division JP2017184759A (ja) | 2008-04-09 | 2017-07-05 | 新規に単離された細胞の治療組成物の操作および送達 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020012000A JP2020012000A (ja) | 2020-01-23 |
| JP2020012000A5 true JP2020012000A5 (enExample) | 2020-09-17 |
| JP6944497B2 JP6944497B2 (ja) | 2021-10-06 |
Family
ID=41162602
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011504171A Active JP5779090B2 (ja) | 2008-04-09 | 2009-04-09 | 新規に単離された細胞の治療組成物の操作および送達 |
| JP2015138578A Active JP6630074B2 (ja) | 2008-04-09 | 2015-07-10 | 新規に単離された細胞の治療組成物の操作および送達 |
| JP2017131791A Pending JP2017184759A (ja) | 2008-04-09 | 2017-07-05 | 新規に単離された細胞の治療組成物の操作および送達 |
| JP2019194124A Active JP6944497B2 (ja) | 2008-04-09 | 2019-10-25 | 新規に単離された細胞の治療組成物の操作および送達 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011504171A Active JP5779090B2 (ja) | 2008-04-09 | 2009-04-09 | 新規に単離された細胞の治療組成物の操作および送達 |
| JP2015138578A Active JP6630074B2 (ja) | 2008-04-09 | 2015-07-10 | 新規に単離された細胞の治療組成物の操作および送達 |
| JP2017131791A Pending JP2017184759A (ja) | 2008-04-09 | 2017-07-05 | 新規に単離された細胞の治療組成物の操作および送達 |
Country Status (5)
| Country | Link |
|---|---|
| US (8) | US8450112B2 (enExample) |
| EP (1) | EP2279253B1 (enExample) |
| JP (4) | JP5779090B2 (enExample) |
| DK (1) | DK2279253T3 (enExample) |
| WO (1) | WO2009126789A2 (enExample) |
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| KR101076879B1 (ko) | 2008-04-11 | 2011-10-25 | 주식회사 하이닉스반도체 | 셀프 부스팅을 이용한 플래시 메모리소자의 프로그램 방법 |
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| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| CN112795594B (zh) | 2013-05-14 | 2025-09-19 | 得克萨斯州大学系统董事会 | 工程化嵌合抗原受体(car)t细胞的人应用 |
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2009
- 2009-04-09 JP JP2011504171A patent/JP5779090B2/ja active Active
- 2009-04-09 US US12/421,352 patent/US8450112B2/en active Active
- 2009-04-09 EP EP09731422.3A patent/EP2279253B1/en active Active
- 2009-04-09 WO PCT/US2009/040040 patent/WO2009126789A2/en not_active Ceased
- 2009-04-09 DK DK09731422.3T patent/DK2279253T3/en active
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2013
- 2013-05-24 US US13/902,444 patent/US9132153B2/en active Active
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2015
- 2015-07-10 JP JP2015138578A patent/JP6630074B2/ja active Active
- 2015-08-25 US US14/834,932 patent/US9669058B2/en active Active
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2017
- 2017-05-23 US US15/602,536 patent/US10660917B2/en active Active
- 2017-07-05 JP JP2017131791A patent/JP2017184759A/ja active Pending
- 2017-10-06 US US15/726,740 patent/US11331344B2/en active Active
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2020
- 2020-04-15 US US16/849,954 patent/US20200237825A1/en not_active Abandoned
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2022
- 2022-05-16 US US17/744,970 patent/US20220265722A1/en not_active Abandoned
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