JP2021506243A5 - - Google Patents
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- Publication number
- JP2021506243A5 JP2021506243A5 JP2020531949A JP2020531949A JP2021506243A5 JP 2021506243 A5 JP2021506243 A5 JP 2021506243A5 JP 2020531949 A JP2020531949 A JP 2020531949A JP 2020531949 A JP2020531949 A JP 2020531949A JP 2021506243 A5 JP2021506243 A5 JP 2021506243A5
- Authority
- JP
- Japan
- Prior art keywords
- cell line
- immortalized
- cell
- seq
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762598032P | 2017-12-13 | 2017-12-13 | |
| US62/598,032 | 2017-12-13 | ||
| PCT/US2018/064971 WO2019118475A1 (en) | 2017-12-13 | 2018-12-11 | Immortalized car-t cells genetically modified to eliminate t-cell receptor and beta 2-microglobulin expression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021506243A JP2021506243A (ja) | 2021-02-22 |
| JP2021506243A5 true JP2021506243A5 (enExample) | 2022-01-11 |
Family
ID=66734891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531949A Pending JP2021506243A (ja) | 2017-12-13 | 2018-12-11 | Ｔ細胞受容体及びβ２ミクログロブリン発現を排除するように遺伝子改変された不死化ＣＡＲ−Ｔ細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20200332255A1 (enExample) |
| EP (1) | EP3724321A4 (enExample) |
| JP (1) | JP2021506243A (enExample) |
| KR (1) | KR20200088383A (enExample) |
| CN (1) | CN111479917A (enExample) |
| AU (1) | AU2018386010A1 (enExample) |
| CA (1) | CA3082204A1 (enExample) |
| SG (1) | SG11202003864XA (enExample) |
| WO (1) | WO2019118475A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9725710B2 (en) | 2014-01-08 | 2017-08-08 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| AU2017378226A1 (en) | 2016-12-14 | 2019-06-20 | Janssen Biotech, Inc. | CD8A-binding fibronectin type III domains |
| EP3554535A4 (en) | 2016-12-14 | 2020-10-21 | Janssen Biotech, Inc. | PD-L1 BINDING FIBRONECTIN TYPE III DOMAINS |
| EP3554561B1 (en) | 2016-12-14 | 2023-06-28 | Janssen Biotech, Inc. | Cd137 binding fibronectin type iii domains |
| EP3596108A4 (en) | 2017-03-15 | 2020-12-23 | Pandion Operations, Inc. | TARGETED IMMUNOTOLERANCE |
| AU2018273914A1 (en) | 2017-05-24 | 2019-11-14 | Pandion Operations, Inc. | Targeted immunotolerance |
| US11161897B2 (en) * | 2017-07-17 | 2021-11-02 | Janssen Biotech, Inc. | Antigen binding regions against fibronectin type III domains and methods of using the same |
| US10174091B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| TW202110885A (zh) | 2019-05-20 | 2021-03-16 | 美商潘迪恩治療公司 | 靶向ＭＡｄＣＡＭ之免疫耐受性 |
| CN114174346B (zh) * | 2019-07-26 | 2025-08-01 | 詹森生物科技公司 | 抗hk2嵌合抗原受体(car) |
| CN114729325A (zh) | 2019-09-06 | 2022-07-08 | 克里斯珀医疗股份公司 | 在培养物中具有改善的持久性的基因工程化t细胞 |
| EP4045061A4 (en) * | 2019-10-14 | 2024-04-17 | ARO Biotherapeutics Company | CD71-BINDING FIBRONECTIN TYPE III DOMAINS |
| US12491255B2 (en) | 2019-10-14 | 2025-12-09 | Aro Biotherapeutics Company | EPCAM binding fibronectin type III domains |
| WO2021076574A2 (en) | 2019-10-14 | 2021-04-22 | Aro Biotherapeutics Company | Fn3 domain-sirna conjugates and uses thereof |
| WO2021168079A1 (en) | 2020-02-21 | 2021-08-26 | Pandion Operations, Inc. | Tissue targeted immunotolerance with a cd39 effector |
| WO2022113056A1 (en) | 2020-11-30 | 2022-06-02 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| TW202237827A (zh) | 2020-12-03 | 2022-10-01 | 美商世紀治療股份有限公司 | 經基因工程改造之細胞及其用途 |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| EP4271798A1 (en) | 2020-12-30 | 2023-11-08 | CRISPR Therapeutics AG | Compositions and methods for differentiating stem cells into nk cells |
| KR20240031947A (ko) | 2021-04-14 | 2024-03-08 | 에이알오 바이오테라퓨틱스 컴패니 | Fn3 도메인-시르나 접합체 및 이의 용도 |
| CA3214552A1 (en) * | 2021-04-14 | 2022-10-20 | Russell C. Addis | Cd71 binding fibronectin type iii domains |
| EP4349857A4 (en) * | 2021-05-25 | 2025-06-11 | Vaxcell-Bio | Monobody-based chimeric antigen receptor and immune cell including same |
| CN118355111A (zh) * | 2021-09-10 | 2024-07-16 | 凯特制药公司 | 同种异体人t细胞的可替代产生 |
| CN116023496B (zh) * | 2021-10-27 | 2026-02-27 | 菲鹏弘济生物(深圳)有限公司 | 一种制备通用型car-t细胞的方法及其应用 |
| US12006353B2 (en) | 2022-07-25 | 2024-06-11 | Long Chen | Application of SCFV protein, car gene expression vector, CAR-T cell and application thereof |
| WO2024173937A1 (en) * | 2023-02-17 | 2024-08-22 | The Regents Of The University Of California | Pluripotent stem cell-engineered immune cells for off-the-shelf cell therapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX387605B (es) * | 2011-09-27 | 2025-03-18 | Janssen Biotech Inc | Supercontigos de proteina basados en repeticiones de fibronectina tipo iii con superficies de union alternativas |
| WO2015136001A1 (en) * | 2014-03-11 | 2015-09-17 | Cellectis | Method for generating t-cells compatible for allogenic transplantation |
| US10174095B2 (en) * | 2014-07-21 | 2019-01-08 | Novartis Ag | Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor |
| AU2015339743C1 (en) * | 2014-10-31 | 2021-04-22 | The Trustees Of The University Of Pennsylvania | Altering gene expression in modified T cells and uses thereof |
| WO2016179534A2 (en) * | 2015-05-06 | 2016-11-10 | Janssen Biotech, Inc. | Prostate specific membrane antigen binding fibronectin type iii domains |
| WO2017106528A2 (en) * | 2015-12-18 | 2017-06-22 | Sangamo Biosciences, Inc. | Targeted disruption of the t cell receptor |
| MX2018007519A (es) * | 2015-12-18 | 2019-09-04 | Sangamo Therapeutics Inc | Alteracion dirigida del receptor celular del complejo mayor de histocompatibilidad (mhc). |
| ES2901000T3 (es) * | 2015-12-23 | 2022-03-21 | Prec Biosciences Inc | Meganucleasas de ingeniería con secuencias de reconocimiento encontradas en el gen de la microglobulina beta-2 humana |
| CN109715199A (zh) * | 2016-09-14 | 2019-05-03 | 詹森生物科技公司 | 包含bcma特异性iii型纤连蛋白结构域的嵌合抗原受体及其用途 |
-
2018
- 2018-12-11 CN CN201880080452.1A patent/CN111479917A/zh active Pending
- 2018-12-11 AU AU2018386010A patent/AU2018386010A1/en not_active Abandoned
- 2018-12-11 WO PCT/US2018/064971 patent/WO2019118475A1/en not_active Ceased
- 2018-12-11 EP EP18888643.6A patent/EP3724321A4/en not_active Withdrawn
- 2018-12-11 KR KR1020207016631A patent/KR20200088383A/ko not_active Ceased
- 2018-12-11 CA CA3082204A patent/CA3082204A1/en active Pending
- 2018-12-11 SG SG11202003864XA patent/SG11202003864XA/en unknown
- 2018-12-11 JP JP2020531949A patent/JP2021506243A/ja active Pending
- 2018-12-11 US US16/770,809 patent/US20200332255A1/en not_active Abandoned
- 2018-12-11 US US16/215,716 patent/US20190175651A1/en not_active Abandoned
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