JP2021506243A - T細胞受容体及びβ2ミクログロブリン発現を排除するように遺伝子改変された不死化CAR−T細胞 - Google Patents
T細胞受容体及びβ2ミクログロブリン発現を排除するように遺伝子改変された不死化CAR−T細胞 Download PDFInfo
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- JP2021506243A JP2021506243A JP2020531949A JP2020531949A JP2021506243A JP 2021506243 A JP2021506243 A JP 2021506243A JP 2020531949 A JP2020531949 A JP 2020531949A JP 2020531949 A JP2020531949 A JP 2020531949A JP 2021506243 A JP2021506243 A JP 2021506243A
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762598032P | 2017-12-13 | 2017-12-13 | |
| US62/598,032 | 2017-12-13 | ||
| PCT/US2018/064971 WO2019118475A1 (en) | 2017-12-13 | 2018-12-11 | Immortalized car-t cells genetically modified to eliminate t-cell receptor and beta 2-microglobulin expression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021506243A true JP2021506243A (ja) | 2021-02-22 |
| JP2021506243A5 JP2021506243A5 (enExample) | 2022-01-11 |
Family
ID=66734891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531949A Pending JP2021506243A (ja) | 2017-12-13 | 2018-12-11 | T細胞受容体及びβ2ミクログロブリン発現を排除するように遺伝子改変された不死化CAR−T細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20190175651A1 (enExample) |
| EP (1) | EP3724321A4 (enExample) |
| JP (1) | JP2021506243A (enExample) |
| KR (1) | KR20200088383A (enExample) |
| CN (1) | CN111479917A (enExample) |
| AU (1) | AU2018386010A1 (enExample) |
| CA (1) | CA3082204A1 (enExample) |
| SG (1) | SG11202003864XA (enExample) |
| WO (1) | WO2019118475A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9725710B2 (en) | 2014-01-08 | 2017-08-08 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| EP3554535A4 (en) | 2016-12-14 | 2020-10-21 | Janssen Biotech, Inc. | PD-L1 BINDING FIBRONECTIN TYPE III DOMAINS |
| KR102568559B1 (ko) | 2016-12-14 | 2023-08-18 | 얀센 바이오테크 인코포레이티드 | Cd8a-결합 섬유결합소 iii형 도메인 |
| US10611823B2 (en) | 2016-12-14 | 2020-04-07 | Hanssen Biotech, Inc | CD137 binding fibronectin type III domains |
| BR112019018915A2 (pt) | 2017-03-15 | 2020-04-14 | Pandion Therapeutics Inc | imunotolerância direcionada |
| CN111010866A (zh) | 2017-05-24 | 2020-04-14 | 潘迪恩治疗公司 | 靶向免疫耐受性 |
| KR102869563B1 (ko) * | 2017-07-17 | 2025-10-10 | 얀센 바이오테크 인코포레이티드 | 피브로넥틴 iii형 도메인에 대한 항원 결합 영역 및 이의 사용 방법 |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10174092B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US11739146B2 (en) | 2019-05-20 | 2023-08-29 | Pandion Operations, Inc. | MAdCAM targeted immunotolerance |
| CA3148735A1 (en) | 2019-07-26 | 2021-02-04 | Janssen Biotech, Inc. | Anti-hk2 chimeric antigen receptor (car) |
| BR112022003891A2 (pt) | 2019-09-06 | 2022-05-31 | Crispr Therapeutics Ag | Células t geneticamente manipuladas possuindo persistência melhorada em cultura |
| WO2021076574A2 (en) | 2019-10-14 | 2021-04-22 | Aro Biotherapeutics Company | Fn3 domain-sirna conjugates and uses thereof |
| WO2021076546A1 (en) * | 2019-10-14 | 2021-04-22 | Aro Biotherapeutics Company | Cd71 binding fibronectin type iii domains |
| US12491255B2 (en) | 2019-10-14 | 2025-12-09 | Aro Biotherapeutics Company | EPCAM binding fibronectin type III domains |
| US11981715B2 (en) | 2020-02-21 | 2024-05-14 | Pandion Operations, Inc. | Tissue targeted immunotolerance with a CD39 effector |
| US11591381B2 (en) | 2020-11-30 | 2023-02-28 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
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| EP3724321A1 (en) | 2020-10-21 |
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| WO2019118475A1 (en) | 2019-06-20 |
| KR20200088383A (ko) | 2020-07-22 |
| EP3724321A4 (en) | 2021-09-01 |
| CA3082204A1 (en) | 2019-06-20 |
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