JP2019536818A5 - - Google Patents

Download PDF

Info

Publication number
JP2019536818A5
JP2019536818A5 JP2019548783A JP2019548783A JP2019536818A5 JP 2019536818 A5 JP2019536818 A5 JP 2019536818A5 JP 2019548783 A JP2019548783 A JP 2019548783A JP 2019548783 A JP2019548783 A JP 2019548783A JP 2019536818 A5 JP2019536818 A5 JP 2019536818A5
Authority
JP
Japan
Prior art keywords
myopathy
muscle
disease
loss
atrophy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019548783A
Other languages
English (en)
Japanese (ja)
Other versions
JP7683901B2 (ja
JP2019536818A (ja
Filing date
Publication date
Priority claimed from GBGB1620119.6A external-priority patent/GB201620119D0/en
Application filed filed Critical
Publication of JP2019536818A publication Critical patent/JP2019536818A/ja
Publication of JP2019536818A5 publication Critical patent/JP2019536818A5/ja
Priority to JP2023083666A priority Critical patent/JP2023116479A/ja
Application granted granted Critical
Publication of JP7683901B2 publication Critical patent/JP7683901B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2019548783A 2016-11-29 2017-11-28 筋肉性能改善化合物 Active JP7683901B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023083666A JP2023116479A (ja) 2016-11-29 2023-05-22 筋肉性能改善化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1620119.6 2016-11-29
GBGB1620119.6A GB201620119D0 (en) 2016-11-29 2016-11-29 Compounds
PCT/IB2017/057436 WO2018100483A1 (en) 2016-11-29 2017-11-28 Muscle performance improvement compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023083666A Division JP2023116479A (ja) 2016-11-29 2023-05-22 筋肉性能改善化合物

Publications (3)

Publication Number Publication Date
JP2019536818A JP2019536818A (ja) 2019-12-19
JP2019536818A5 true JP2019536818A5 (cg-RX-API-DMAC7.html) 2021-01-14
JP7683901B2 JP7683901B2 (ja) 2025-05-27

Family

ID=58073474

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019548783A Active JP7683901B2 (ja) 2016-11-29 2017-11-28 筋肉性能改善化合物
JP2023083666A Pending JP2023116479A (ja) 2016-11-29 2023-05-22 筋肉性能改善化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023083666A Pending JP2023116479A (ja) 2016-11-29 2023-05-22 筋肉性能改善化合物

Country Status (11)

Country Link
US (1) US11407799B2 (cg-RX-API-DMAC7.html)
EP (1) EP3548509A1 (cg-RX-API-DMAC7.html)
JP (2) JP7683901B2 (cg-RX-API-DMAC7.html)
KR (1) KR102622245B1 (cg-RX-API-DMAC7.html)
CN (1) CN110036024B (cg-RX-API-DMAC7.html)
AU (1) AU2017367277B2 (cg-RX-API-DMAC7.html)
CA (1) CA3045245A1 (cg-RX-API-DMAC7.html)
GB (1) GB201620119D0 (cg-RX-API-DMAC7.html)
NZ (1) NZ754625A (cg-RX-API-DMAC7.html)
WO (1) WO2018100483A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201903261B (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11013785B2 (en) 2016-11-10 2021-05-25 Keros Therapeutics, Inc. Activin receptor type IIA variants and methods of use thereof
KR20200085832A (ko) 2017-11-09 2020-07-15 케로스 테라퓨틱스, 인크. 액티빈 수용체 유형 iia 변이체 및 그의 사용 방법
CN120535607A (zh) 2018-01-12 2025-08-26 科乐斯疗法公司 激活素受体iib型变体及其使用方法
AU2019266314B2 (en) 2018-05-09 2025-05-15 Keros Therapeutics, Inc. Activin receptor type iia variants and methods of use thereof
JP2023512423A (ja) * 2019-12-24 2023-03-27 ジュベナ・セラピューティクス・インコーポレイテッド 再生性ポリペプチドおよびその使用
EP4121090A4 (en) * 2020-03-20 2024-09-04 Keros Therapeutics, Inc. Methods of using activin receptor type iia variants
EP4121088A4 (en) * 2020-03-20 2024-07-03 Keros Therapeutics, Inc. Methods of using activin receptor type iib variants
EP4185316A4 (en) * 2020-07-24 2024-07-17 Agency for Science, Technology and Research WOUND HEALING COMPOSITION AND USES THEREOF
BR112023018283A2 (pt) * 2021-03-10 2023-10-31 Acceleron Pharma Inc Antagonistas de actrii-alk4 e métodos para tratar insuficiência cardíaca
KR20230169123A (ko) * 2021-03-10 2023-12-15 악셀레론 파마 인코포레이티드 Actrii-alk4 길항제 및 심부전을 치료하는 방법
CN117999278A (zh) 2021-06-21 2024-05-07 裘美娜治疗公司 再生性多肽及其用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09503673A (ja) * 1993-10-14 1997-04-15 プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ ニューロン細胞の誘導および維持法
US20040223966A1 (en) 2002-10-25 2004-11-11 Wolfman Neil M. ActRIIB fusion polypeptides and uses therefor
US7355018B2 (en) * 2003-09-30 2008-04-08 Regeneron Pharmaceuticals, Inc. Modified IGF1 polypeptides with increased stability and potency
US20060216279A1 (en) * 2005-03-22 2006-09-28 Glass David J Myostatin inhibiting fusion polypeptides and therapeutic methods thereof
EP2056850A4 (en) 2006-08-08 2011-10-12 Univ Louisiana State THERAPEUTIC PROCEDURES FOR NEUROPATHIC PAIN
BRPI0716249A2 (pt) * 2006-09-05 2013-09-03 Lilly Co Eli anticorpos antimiostatina
KR101672156B1 (ko) 2007-02-09 2016-11-02 악셀레론 파마 인코포레이티드 액티빈-ActRⅡA 길항제 및 암 환자에서 골 생장을 촉진시키기 위한 이의 용도
HUE035240T2 (hu) * 2009-04-27 2018-05-02 Novartis Ag Készítmények és eljárások az izomerõ növelésére
CN107267520A (zh) 2009-06-12 2017-10-20 阿塞勒隆制药公司 截短的actriib‑fc融合蛋白
US9676845B2 (en) * 2009-06-16 2017-06-13 Hoffmann-La Roche, Inc. Bispecific antigen binding proteins
EP2295068A1 (en) * 2009-09-04 2011-03-16 Neurotune AG Modified agrin-fragment capable of restoring muscle strength for use as a medicament
US8710016B2 (en) * 2009-11-17 2014-04-29 Acceleron Pharma, Inc. ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy

Similar Documents

Publication Publication Date Title
JP2019536818A5 (cg-RX-API-DMAC7.html)
JP2019535675A5 (cg-RX-API-DMAC7.html)
Braun et al. Renal expression of the C3a receptor and functional responses of primary human proximal tubular epithelial cells
Abu-Shakra et al. Cancer and autoimmunity: autoimmune and rheumatic features in patients with malignancies
JP2012070739A5 (cg-RX-API-DMAC7.html)
Flesch et al. Nonacidic farnesoid X receptor modulators
TWI826358B (zh) 用於治療肌肉萎縮和骨疾病的新型雜合actriib配體陷阱蛋白及其用途與生產方法
JP2014158480A5 (cg-RX-API-DMAC7.html)
Poggiogalle et al. Fatty liver index associates with relative sarcopenia and GH/IGF-1 status in obese subjects
US8309525B2 (en) Treatment of type 2 diabetes, metabolic syndrome, myocardial injury and neurodegeneration with humanin and analogs thereof
BR122020006907B1 (pt) Anticorpo de domínio único anti-kras e seu uso, métodos in vitro para medir os níveis do referido anticorpo e para diagnosticar um distúrbio mediado por um componente intracelular, polipetídeo isolado e composição compreendendo o referido anticorpo ou polipeptídeo isolado
JP2017019804A (ja) ペプチド模倣大環状分子
RU2017138537A (ru) Новые гибридные ActRIIB белки-ловушки лигандов для лечения заболеваний, связанных с мышечной атрофией
JP2015091868A5 (cg-RX-API-DMAC7.html)
JP2006517581A5 (cg-RX-API-DMAC7.html)
JP2017533889A (ja) ペプチド模倣大環状分子およびその使用
JP2014502141A5 (cg-RX-API-DMAC7.html)
TW201000467A (en) Novel 1,2,4-triazole derivatives and process of manufacturing thereof
JP2022542016A (ja) TDP-43、α-シヌクレイン、ハンチンチンタンパク質及びタウタンパク質のオリゴマー形成に関連する疾患を治療するための小分子薬物、並びに関連する方法
US20140004136A1 (en) Phosphorylated derivatives of a u1-70k peptide and their use in the treatment of autoimmune pathologies
Islam et al. Incorporation of α-methylated amino acids into Apolipoprotein AI mimetic peptides improves their helicity and cholesterol efflux potential
Reilich et al. A novel mutation in the myotilin gene (MYOT) causes a severe form of limb girdle muscular dystrophy 1A (LGMD1A)
Li et al. Basic biology and roles of CEBPD in cardiovascular disease
Sahlholm et al. Sigma-2 receptor binding is decreased in female, but not male, APP/PS1 mice
Dodson et al. Crystal structure, aggregation and biological potency of beef insulin cross-linked at A1 and B29 by diaminosuberic acid