JP2019536770A5 - - Google Patents

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Publication number
JP2019536770A5
JP2019536770A5 JP2019524074A JP2019524074A JP2019536770A5 JP 2019536770 A5 JP2019536770 A5 JP 2019536770A5 JP 2019524074 A JP2019524074 A JP 2019524074A JP 2019524074 A JP2019524074 A JP 2019524074A JP 2019536770 A5 JP2019536770 A5 JP 2019536770A5
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JP
Japan
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alkyl
item
heteroalkyl
amino
substituted
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JP2019524074A
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English (en)
Japanese (ja)
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JP2019536770A (ja
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Priority claimed from PCT/US2017/060721 external-priority patent/WO2018089554A1/en
Publication of JP2019536770A publication Critical patent/JP2019536770A/ja
Publication of JP2019536770A5 publication Critical patent/JP2019536770A5/ja
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JP2019524074A 2016-11-09 2017-11-08 予め会合され、保護され、化学的に安定した、官能基選択的リンカー Withdrawn JP2019536770A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662419861P 2016-11-09 2016-11-09
US62/419,861 2016-11-09
PCT/US2017/060721 WO2018089554A1 (en) 2016-11-09 2017-11-08 Pre-assembled, protected, chemically stable, chemoselective linkers

Publications (2)

Publication Number Publication Date
JP2019536770A JP2019536770A (ja) 2019-12-19
JP2019536770A5 true JP2019536770A5 (enExample) 2020-12-17

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ID=62109408

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019524074A Withdrawn JP2019536770A (ja) 2016-11-09 2017-11-08 予め会合され、保護され、化学的に安定した、官能基選択的リンカー

Country Status (8)

Country Link
US (1) US12037311B2 (enExample)
EP (1) EP3538536A4 (enExample)
JP (1) JP2019536770A (enExample)
KR (1) KR20190082871A (enExample)
CN (2) CN110072870A (enExample)
AU (1) AU2017359448A1 (enExample)
CA (1) CA3043373A1 (enExample)
WO (1) WO2018089554A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017223117A1 (en) 2016-06-20 2017-12-28 Healthtell Inc. Methods for diagnosis and treatment of autoimmune diseases
KR20190020106A (ko) 2016-06-20 2019-02-27 헬스텔 인크. 자가면역 질환의 차별적 진단 방법
CN110072870A (zh) 2016-11-09 2019-07-30 健康之语公司 预组装的、受保护的、化学稳定的化学选择性接头
EP3538591A4 (en) 2016-11-09 2020-07-29 Healthtell Inc. ADJUSTABLE AMINE DENSITY COATINGS
CN110168370A (zh) 2016-11-11 2019-08-23 健康之语公司 用于鉴定候选生物标志物的方法

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5981478A (en) 1993-11-24 1999-11-09 La Jolla Cancer Research Foundation Integrin-binding peptides
US5571639A (en) 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US5932546A (en) 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
US6261804B1 (en) 1997-01-21 2001-07-17 The General Hospital Corporation Selection of proteins using RNA-protein fusions
US6824866B1 (en) 1999-04-08 2004-11-30 Affymetrix, Inc. Porous silica substrates for polymer synthesis and assays
GB0001513D0 (en) 2000-01-25 2000-03-15 Univ Cranfield Rational design of mips using computational approach
EP2279757A3 (en) * 2000-06-02 2011-08-03 Bracco Suisse SA Compounds for targeting endothelial cells
US20030219816A1 (en) 2001-07-02 2003-11-27 Keith Solomon Composite microarray slides
CN1125488C (zh) 2000-08-25 2003-10-22 中国科学院化学研究所 一种半导体封装用的液体环氧组合物及其用途
AU2002257132A1 (en) 2001-04-06 2002-10-21 The Trustees Of The University Of Pennsylvania Erbb interface peptidomimetics and methods of use thereof
US20030003223A1 (en) 2001-04-07 2003-01-02 The Regents Of The University Of California Methods and compositions for binding histidine-containing proteins to substrates
GB0121602D0 (en) 2001-09-06 2001-10-24 Randox Lab Ltd Molecular array
EP1518115A2 (en) 2002-06-10 2005-03-30 Phynexus, Inc. Biomolecule open channel solid phase extraction systems and methods
US20060013971A1 (en) 2002-10-25 2006-01-19 Tienteh Chen Porous inkjet recording material
AU2003300815A1 (en) 2002-12-05 2004-06-30 Incyte Corporation Protein modification and maintenance molecules
KR100529600B1 (ko) 2003-01-23 2005-11-22 정만길 디옥소아테미시닌 유사체, 그의 제조방법 및 그를포함하는 항암제
JP4006523B2 (ja) 2003-04-10 2007-11-14 独立行政法人産業技術総合研究所 タンパク質アレイ及びその作製方法
WO2005050224A2 (en) 2003-11-13 2005-06-02 Epitome Biosystems Inc. Small molecule and peptide arrays and uses thereof
US7994118B2 (en) 2003-11-15 2011-08-09 Polyphor Ltd. Template fixed beta-hairpin loop mimetics and their use in phage display
EP1853634B1 (en) 2005-02-23 2016-08-10 Lipoxen Technologies Limited Activated sialic acid derivatives for protein derivatisation and conjugation
BRPI0608516A2 (pt) 2005-03-18 2010-11-16 Novo Nordisk As análogo de glp-1, método para aumentar o tempo de ação em um paciente de um análogo de glp-1, composição farmacêutica, e, uso de um composto
US7507480B2 (en) 2005-05-31 2009-03-24 Brookhaven Science Associates, Llc Corrosion-resistant metal surfaces
KR100671659B1 (ko) * 2005-12-21 2007-01-19 삼성에스디아이 주식회사 데이터 구동부 및 이를 이용한 유기 발광 표시장치와 그의구동방법
US7923054B2 (en) 2006-04-19 2011-04-12 Gore Enterprise Holdings, Inc. Functional porous substrates for attaching biomolecules
WO2007144685A1 (en) 2006-06-13 2007-12-21 Commissariat A L'energie Atomique Cd4 mimic peptides and their uses
US8148084B2 (en) 2006-06-22 2012-04-03 Dana-Farber Cancer Institute, Inc. Diagnosis of autoimmune disease
JP2008028123A (ja) 2006-07-20 2008-02-07 Sanyo Electric Co Ltd 半導体集積回路装置の製造方法
WO2008064336A2 (en) 2006-11-22 2008-05-29 Inivitrogen Corporation Autoimmune disease biomarkers
WO2008151146A2 (en) 2007-06-01 2008-12-11 Digitab, Inc. Peptide arrays and methods of use
US20090142792A1 (en) 2007-06-21 2009-06-04 Robinson William H Biomarkers for the diagnosis of autoimmune disease
JP2011001344A (ja) 2009-04-30 2011-01-06 L'oreal Sa アミノトリアルコキシシランまたはアミノトリアルケニルオキシシラン組成物を用いたヒトケラチン繊維の明色化および/または着色ならびに装置
JP6059014B2 (ja) 2009-06-19 2017-01-11 アリゾナ ボード オブ リージェンツ ア ボディー コーポレート アクティング オン ビハーフ オブ アリゾナ ステイト ユニバーシティARIZONA BOARD OF REGENTS,a body corporate acting on behalf of ARIZONA STATE UNIVERSITY 試料の構成成分の検出において使用されるデバイスを製造する方法およびペプチドアレイ
CA2768149A1 (en) 2009-07-14 2011-01-20 Lucia Irene Gonzalez Stereoisomer peptides and their polymer conjugates for hiv disease
WO2011041586A1 (en) * 2009-09-30 2011-04-07 Virogenomics, Inc. Electromagnetic detection of analytes
US8698320B2 (en) 2009-12-07 2014-04-15 Henkel IP & Holding GmbH Curable resin compositions useful as underfill sealants for use with low-k dielectric-containing semiconductor devices
US20130071860A1 (en) 2010-02-24 2013-03-21 Matthew B. Hale Methods for autoimmune disease diagnosis, prognosis, and treatment`
US20120237555A1 (en) 2011-03-16 2012-09-20 David Williams Surface coating for biomolecule immobilisation and minimisation of non-specific binding on surfaces for biomedical diagnostics
US9346892B2 (en) 2011-03-18 2016-05-24 Roche Nimble Gen, Inc. Methods for synthesis of an oligopeptide microarray
WO2013077982A1 (en) 2011-11-22 2013-05-30 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf High throughput selection of specific cell binding and lytic polypeptides
CA3191015A1 (en) 2012-02-07 2013-08-15 Vibrant Holdings, Llc Substrates, peptide arrays, and methods
US20130310265A1 (en) 2012-03-21 2013-11-21 North Carolina State University Methods of preparing cyclic peptides and uses thereof
SI2869848T1 (sl) 2012-07-04 2017-01-31 F. Hoffmann-La Roche Ag Kovalentno vezani konjugati antigen-protitelo
GB2525743A (en) 2012-08-29 2015-11-04 Univ Arizona Immunosignaturing: a path to early diagnosis and health monitoring
WO2014039718A1 (en) 2012-09-05 2014-03-13 Arizona Board of Regents, a body Corporate of the State of Arizona, Acting for and on Behalf of Ariz Methods for discovering therapeutic targets
US10046293B2 (en) 2012-10-17 2018-08-14 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona In situ chemical patterning
WO2014144383A1 (en) * 2013-03-15 2014-09-18 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Non-covalent patterned chemical features and use thereof in maldi-based quality control
EP4610368B1 (en) 2013-08-05 2026-02-04 Twist Bioscience Corporation De novo synthesized gene libraries
EP3169812A4 (en) 2014-07-18 2017-12-20 CDI Laboratories Inc. Methods and compositions to identify, quantify, and characterize target analytes and binding moieties
HRP20201153T1 (hr) 2014-08-08 2021-01-22 The Board Of Trustees Of The Leland Stanford Junior University Pd-1 sredstva visokog afiniteta i načini uporabe
US20160367961A1 (en) 2015-04-23 2016-12-22 Roche Sequencing Solutions, Inc. Method and composition for peptide cyclization and protease treatment
US10094825B2 (en) 2015-07-30 2018-10-09 The Florida International University Board Of Trustees Predictive biomarkers for detection of organ damage in autoimmune illnesses and other diseases
JP2019520421A (ja) 2016-04-01 2019-07-18 ヘルステル・インコーポレイテッドHealthtell Inc. 治療抗体の特徴付けのためのアレイに基づくペプチドライブラリー
CN110072870A (zh) 2016-11-09 2019-07-30 健康之语公司 预组装的、受保护的、化学稳定的化学选择性接头
EP3538591A4 (en) 2016-11-09 2020-07-29 Healthtell Inc. ADJUSTABLE AMINE DENSITY COATINGS
WO2018236838A2 (en) 2017-06-19 2018-12-27 Healthtell Inc. Immunosignatures for differential diagnosis
WO2019157362A1 (en) 2018-02-09 2019-08-15 Healthtell Inc. Array-based cyclic peptide libraries
WO2020102365A1 (en) 2018-11-14 2020-05-22 Healthtell Inc. Methods of selecting functional interface mimics, and compositions thereof

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