JP2019528061A5 - - Google Patents

Download PDF

Info

Publication number
JP2019528061A5
JP2019528061A5 JP2019508259A JP2019508259A JP2019528061A5 JP 2019528061 A5 JP2019528061 A5 JP 2019528061A5 JP 2019508259 A JP2019508259 A JP 2019508259A JP 2019508259 A JP2019508259 A JP 2019508259A JP 2019528061 A5 JP2019528061 A5 JP 2019528061A5
Authority
JP
Japan
Prior art keywords
cancer
seq
amino acid
acid sequence
antigen recognition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019508259A
Other languages
English (en)
Japanese (ja)
Other versions
JP6964351B2 (ja
JP2019528061A (ja
Filing date
Publication date
Priority claimed from DE102016115246.3A external-priority patent/DE102016115246C5/de
Application filed filed Critical
Publication of JP2019528061A publication Critical patent/JP2019528061A/ja
Publication of JP2019528061A5 publication Critical patent/JP2019528061A5/ja
Priority to JP2021128303A priority Critical patent/JP2021184729A/ja
Application granted granted Critical
Publication of JP6964351B2 publication Critical patent/JP6964351B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2019508259A 2016-08-17 2017-07-04 新規t細胞受容体およびそれを用いた免疫療法 Active JP6964351B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021128303A JP2021184729A (ja) 2016-08-17 2021-08-04 新規t細胞受容体およびそれを用いた免疫療法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662376059P 2016-08-17 2016-08-17
DE102016115246.3A DE102016115246C5 (de) 2016-08-17 2016-08-17 Neue t-zellrezeptoren und deren verwendung in immuntherapie
US62/376,059 2016-08-17
DE102016115246.3 2016-08-17
US201662376632P 2016-08-18 2016-08-18
US62/376,632 2016-08-18
PCT/EP2017/066630 WO2018033291A1 (en) 2016-08-17 2017-07-04 T cell receptors and immune therapy using the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021128303A Division JP2021184729A (ja) 2016-08-17 2021-08-04 新規t細胞受容体およびそれを用いた免疫療法

Publications (3)

Publication Number Publication Date
JP2019528061A JP2019528061A (ja) 2019-10-10
JP2019528061A5 true JP2019528061A5 (https=) 2020-02-20
JP6964351B2 JP6964351B2 (ja) 2021-11-10

Family

ID=60419980

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019508259A Active JP6964351B2 (ja) 2016-08-17 2017-07-04 新規t細胞受容体およびそれを用いた免疫療法
JP2021128303A Pending JP2021184729A (ja) 2016-08-17 2021-08-04 新規t細胞受容体およびそれを用いた免疫療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021128303A Pending JP2021184729A (ja) 2016-08-17 2021-08-04 新規t細胞受容体およびそれを用いた免疫療法

Country Status (18)

Country Link
US (2) US10550182B2 (https=)
EP (1) EP3500593B1 (https=)
JP (2) JP6964351B2 (https=)
CN (1) CN109563149A (https=)
AU (2) AU2017312361B2 (https=)
BR (1) BR112019001922A2 (https=)
CA (1) CA3031995A1 (https=)
CR (1) CR20190095A (https=)
DE (1) DE102016115246C5 (https=)
DK (1) DK3500593T3 (https=)
LT (1) LT3500593T (https=)
MA (1) MA45976B1 (https=)
MX (1) MX395287B (https=)
PE (1) PE20190477A1 (https=)
RS (1) RS62498B1 (https=)
SG (1) SG11201900955VA (https=)
TW (1) TWI775768B (https=)
WO (1) WO2018033291A1 (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021173560A1 (en) 2020-02-24 2021-09-02 Immatics US, Inc. Methods for expanding t cells for the treatment of cancer and related malignancies
GB201423361D0 (en) * 2014-12-30 2015-02-11 Immatics Biotechnologies Gmbh Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
ZA201900664B (en) * 2016-08-17 2021-09-29 Paul Ehrlich Strasse 15 Tuebingen 72076 Germany T cell receptors and immune therapy using the same
MX2019010972A (es) * 2017-03-15 2019-12-02 Hutchinson Fred Cancer Res Receptores de linfocito t (tcr) específicos del antígeno asociado a melanoma 1 (mage-a1) de alta afinidad y usos de estos.
CN111655280B (zh) 2017-09-01 2025-01-14 达纳-法伯癌症研究所股份有限公司 用于治疗癌症的bcma和taci抗原特异的免疫原性肽
DE102017125888A1 (de) 2017-11-06 2019-05-23 Immatics Biotechnologies Gmbh Neue konstruierte T-Zell-Rezeptoren und deren Verwendung in Immuntherapie
EP4219543A1 (en) 2017-11-06 2023-08-02 Immatics Biotechnologies GmbH Novel engineered t cell receptors and immune therapy using the same
EP3749753B1 (en) 2018-02-09 2025-04-02 Immatics US, Inc. Methods for manufacturing t cells
DE102018108612A1 (de) 2018-03-21 2019-09-26 Immatics US, Inc. Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen
WO2019243312A1 (en) 2018-06-19 2019-12-26 Dsm Ip Assets B.V. Lipolytic enzyme variants
CN113412277B (zh) 2019-01-22 2025-07-18 美国卫生和人力服务部 针对含有g12r突变的ras的hla第ii类限制性t细胞受体
US12448429B2 (en) 2019-03-06 2025-10-21 Dana-Farber Cancer Institute, Inc. T cell receptors specific to b-cell maturation antigen for treatment of cancer
WO2020191172A1 (en) 2019-03-19 2020-09-24 Immatics US, Inc. Cd28 t cell cultures, compositions, and methods of using thereof
DE102019108125B4 (de) 2019-03-28 2022-02-03 Immatics US, Inc. Cd28 t-zellkulturen, zusammensetzungen und verfahren zu deren verwendung
WO2020243134A1 (en) 2019-05-27 2020-12-03 Immatics US, Inc. Viral vectors and their use in adoptive cellular therapy
MX2021015033A (es) 2019-06-06 2022-01-18 Immatics Biotechnologies Gmbh Clasificacion con contraseleccion utilizando peptidos de secuencias similares.
US20210032370A1 (en) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Recruiting agent further binding an mhc molecule
DE102020111571A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
DE102020106710A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
CA3171370A1 (en) * 2020-03-16 2021-09-23 Ugur Sahin Antigen-specific t cell receptors and t cell epitopes
CN116096740A (zh) * 2020-06-09 2023-05-09 得克萨斯州大学系统董事会 经改造t细胞受体和使用方法
TW202227616A (zh) 2020-08-21 2022-07-16 美商英麥提克斯股份有限公司 分離cd8+選擇t細胞的方法
DE102021100038A1 (de) 2020-12-31 2022-06-30 Immatics US, Inc. Modifizierte cd8-polypeptide, zusammensetzungen und verfahren zu deren verwendung
KR20230135589A (ko) 2020-12-31 2023-09-25 이매틱스 유에스 인코포레이티드 Cd8 폴리펩타이드, 조성물 및 이의 사용 방법
US12162940B2 (en) 2021-05-05 2024-12-10 Immatics Biotechnologies Gmbh BMA031 antigen binding polypeptides
JP2024534825A (ja) 2021-08-24 2024-09-26 イマティクス ユーエス,アイエヌシー. 条件付きリガンド交換により産生されたペプチドmhc複合体を使用する免疫細胞の選択
TW202332765A (zh) 2021-09-20 2023-08-16 美商英麥提克斯股份有限公司 用於t細胞療法之t細胞群體的單核球耗盡
CN118541392A (zh) 2021-09-28 2024-08-23 准星生物医药有限公司 多种形式的分子复合物
US20230142468A1 (en) 2021-11-08 2023-05-11 Immatics US, Inc. Methods for generating cell spheroids
EP4448108A1 (en) 2021-11-08 2024-10-23 Immatics Biotechnologies GmbH Adoptive cell therapy combination treatment and compositions thereof
JP2025515604A (ja) 2022-04-28 2025-05-20 イマティクス ユーエス,アイエヌシー. ドミナントネガティブTGFβ受容体ポリペプチド、CD8ポリペプチド、細胞、組成物、およびその使用方法
JP2025515603A (ja) 2022-04-28 2025-05-20 イマティクス ユーエス,アイエヌシー. Il-12ポリペプチド、il-15ポリペプチド、il-18ポリペプチド、cd8ポリペプチド、それらの組成物、およびそれらの使用方法
JP2025516189A (ja) 2022-04-28 2025-05-27 イマティクス ユーエス,アイエヌシー. 膜結合型il-15、cd8ポリペプチド、細胞、組成物、およびそれらの使用方法
US20230355678A1 (en) 2022-05-05 2023-11-09 Immatics US, Inc. Methods for improving t cell efficacy
CN116813744B (zh) * 2023-02-23 2024-02-23 暨南大学 一种识别mage-a3抗原短肽的t细胞受体及其应用
WO2025096649A1 (en) 2023-11-01 2025-05-08 Immatics US, Inc. Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof
WO2026046995A1 (en) * 2024-08-28 2026-03-05 Pairx Bio Pte. Ltd T cell receptors and uses thereof
CN120718134B (zh) * 2025-08-25 2025-12-26 北京立康生命科技有限公司 靶向col6a3肽的t细胞受体及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
ATE300615T1 (de) 1990-08-29 2005-08-15 Genpharm Int Transgene mäuse fähig zur produktion heterologer antikörper
US5714352A (en) 1996-03-20 1998-02-03 Xenotech Incorporated Directed switch-mediated DNA recombination
WO2001058479A1 (en) 2000-02-08 2001-08-16 The Penn State Research Foundation Immunotherapy using interleukin 13 receptor subunit alpha 2
WO2006023382A2 (en) * 2004-08-23 2006-03-02 Albert Einstein College Of Medicine Of Yeshiva University Collagen vi and cancer
EP1762575A1 (en) * 2005-09-12 2007-03-14 Ganymed Pharmaceuticals AG Identification of tumor-associated antigens for diagnosis and therapy
US8105831B2 (en) * 2007-03-09 2012-01-31 University Of Washington Parvoviral production of HLA homozygous cells
GB0911566D0 (en) 2009-07-03 2009-08-12 Immunocore Ltd T cell receptors
US9228007B1 (en) * 2010-03-11 2016-01-05 The Regents Of The University Of California Recombinant human progenitor cells, engineered human thymocytes, and engineered human T cells
GB201004551D0 (en) * 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer
CN110511960B (zh) * 2013-07-15 2023-05-23 美国卫生和人力服务部 抗人乳头瘤病毒16 e6 t细胞受体
AU2015289644A1 (en) * 2014-07-15 2017-02-02 Juno Therapeutics, Inc. Engineered cells for adoptive cell therapy
MX382952B (es) * 2014-11-05 2025-03-13 Genentech Inc Métodos de producción de proteínas de cadena doble en bacterias.

Similar Documents

Publication Publication Date Title
JP2019528061A5 (https=)
JP2026021299A5 (https=)
JP2022058932A5 (https=)
JP2017186337A5 (https=)
ES2565481T3 (es) Anticuerpo anti-PlGF novedoso
JP2019511222A5 (https=)
JP2019536430A5 (https=)
JP2025163055A5 (https=)
JP2021514664A5 (https=)
JP2023139070A5 (https=)
JP2020500523A5 (https=)
JP2009505676A5 (https=)
JP2010531140A5 (https=)
JP2020513745A5 (https=)
JP2016505513A5 (https=)
JP2020512019A5 (https=)
JP2012529281A5 (https=)
JPWO2021155380A5 (https=)
JP2016521692A5 (https=)
JP2017503480A5 (https=)
JPWO2020237227A5 (https=)
JP2020522474A5 (https=)
CN113710688A (zh) 用于治疗血液癌症和实体瘤癌症的嵌合抗原受体修饰的t细胞(car-t)
JP2024016024A5 (https=)
JP2018529661A5 (https=)