JP2022548764A5 - - Google Patents

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Publication number
JP2022548764A5
JP2022548764A5 JP2022517990A JP2022517990A JP2022548764A5 JP 2022548764 A5 JP2022548764 A5 JP 2022548764A5 JP 2022517990 A JP2022517990 A JP 2022517990A JP 2022517990 A JP2022517990 A JP 2022517990A JP 2022548764 A5 JP2022548764 A5 JP 2022548764A5
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JP
Japan
Prior art keywords
amino acid
seq
sequence
acid sequence
cancer
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022517990A
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English (en)
Japanese (ja)
Other versions
JP7627687B2 (ja
JP2022548764A (ja
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Priority claimed from PCT/EP2020/076198 external-priority patent/WO2021053199A1/en
Publication of JP2022548764A publication Critical patent/JP2022548764A/ja
Publication of JP2022548764A5 publication Critical patent/JP2022548764A5/ja
Application granted granted Critical
Publication of JP7627687B2 publication Critical patent/JP7627687B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022517990A 2019-09-20 2020-09-18 Lilrb2に対するシングルドメイン抗体 Active JP7627687B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19306148.8 2019-09-20
EP19306148 2019-09-20
PCT/EP2020/076198 WO2021053199A1 (en) 2019-09-20 2020-09-18 Single-domain antibodies directed against lilrb2

Publications (3)

Publication Number Publication Date
JP2022548764A JP2022548764A (ja) 2022-11-21
JP2022548764A5 true JP2022548764A5 (https=) 2023-09-25
JP7627687B2 JP7627687B2 (ja) 2025-02-06

Family

ID=68654426

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022517990A Active JP7627687B2 (ja) 2019-09-20 2020-09-18 Lilrb2に対するシングルドメイン抗体

Country Status (11)

Country Link
US (1) US20230235050A1 (https=)
EP (1) EP4031572A1 (https=)
JP (1) JP7627687B2 (https=)
KR (1) KR20220128332A (https=)
CN (1) CN115066435B (https=)
AU (1) AU2020351274A1 (https=)
BR (1) BR112022004534A2 (https=)
CA (1) CA3154450A1 (https=)
IL (1) IL291506A (https=)
MX (1) MX2022003365A (https=)
WO (1) WO2021053199A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116333127B (zh) * 2022-06-28 2026-03-24 北京科诺信诚科技有限公司 靶向人lilrb2的纳米抗体及其应用
CN115975029A (zh) * 2022-06-28 2023-04-18 北京科诺信诚科技有限公司 靶向人lilrb2的纳米抗体及其应用
CN119604531A (zh) * 2022-07-29 2025-03-11 盛禾(中国)生物制药有限公司 一种抗ilt4的单域抗体及其应用
CN119768432A (zh) * 2022-08-22 2025-04-04 德琪(杭州)生物有限公司 新颖的抗lilrb2抗体和其用途
WO2024108568A1 (zh) * 2022-11-25 2024-05-30 深圳先进技术研究院 抗人类白细胞抗原-g纳米抗体及其制备方法与应用
CN116789825A (zh) * 2023-05-12 2023-09-22 南京师范大学 抗lilrb1/lilrb2的全人源单域抗体及其应用
CN116789826A (zh) * 2023-05-12 2023-09-22 南京师范大学 抗人lilrb2全人源单域抗体及其应用
CN119176874A (zh) * 2023-06-21 2024-12-24 康源博创生物科技(北京)有限公司 一种能够结合lilrb2的抗体或其抗原结合片段
CN119619509A (zh) * 2023-09-05 2025-03-14 中日友好医院(中日友好临床医学研究所) 一种结直肠癌治疗靶点和血清标志物及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008020079A1 (en) 2006-08-18 2008-02-21 Ablynx N.V. Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling
CA2687633A1 (en) * 2007-05-24 2008-11-27 Ablynx N.V. Amino acid sequences directed against growth factor receptors and polypeptides comprising the same for the treatment of diseases and disorders associated with growth factors and their receptors
WO2011117423A1 (en) 2010-03-26 2011-09-29 Ablynx N.V. Immunoglobulin single variable domains directed against cxcr7
WO2016111947A2 (en) * 2015-01-05 2016-07-14 Jounce Therapeutics, Inc. Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
CA2977544C (en) * 2015-03-06 2023-12-19 The Board Of Regents Of The University Of Texas System Anti-lilrb antibodies and their use in detecting and treating cancer
EA202091540A1 (ru) * 2017-12-22 2021-03-22 Джаунс Терапьютикс, Инк. Антитела к lilrb2
CN111867614A (zh) * 2018-01-18 2020-10-30 艾达奈特公司 抗lilrb抗体及其用途

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