JP2017530692A5 - - Google Patents
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- Publication number
- JP2017530692A5 JP2017530692A5 JP2017506267A JP2017506267A JP2017530692A5 JP 2017530692 A5 JP2017530692 A5 JP 2017530692A5 JP 2017506267 A JP2017506267 A JP 2017506267A JP 2017506267 A JP2017506267 A JP 2017506267A JP 2017530692 A5 JP2017530692 A5 JP 2017530692A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding fragment
- cancer
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1413913.3 | 2014-08-06 | ||
| GBGB1413913.3A GB201413913D0 (en) | 2014-08-06 | 2014-08-06 | Novel antibodies and uses thereof |
| PCT/EP2015/068208 WO2016020502A1 (en) | 2014-08-06 | 2015-08-06 | Novel antibodies and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530692A JP2017530692A (ja) | 2017-10-19 |
| JP2017530692A5 true JP2017530692A5 (https=) | 2018-08-30 |
| JP6827411B2 JP6827411B2 (ja) | 2021-02-10 |
Family
ID=51587804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017506267A Active JP6827411B2 (ja) | 2014-08-06 | 2015-08-06 | 新規の抗体及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10100119B2 (https=) |
| EP (1) | EP3193926B1 (https=) |
| JP (1) | JP6827411B2 (https=) |
| KR (1) | KR20170039685A (https=) |
| CN (1) | CN107074946B (https=) |
| AU (1) | AU2015298852A1 (https=) |
| BR (1) | BR112017002342A2 (https=) |
| CA (1) | CA2955056A1 (https=) |
| GB (1) | GB201413913D0 (https=) |
| MX (1) | MX2017001599A (https=) |
| WO (1) | WO2016020502A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2472856B (en) | 2009-08-21 | 2012-07-11 | Cantargia Ab | IL1-RAP modulators and uses thereof |
| RU2597831C2 (ru) | 2011-01-19 | 2016-09-20 | Кантаргия Аб | Анти-il1rap антитела и их применение при лечении людей |
| GB201403875D0 (en) | 2014-03-05 | 2014-04-16 | Cantargia Ab | Novel antibodies and uses thereof |
| TWI705976B (zh) | 2014-11-10 | 2020-10-01 | 美商建南德克公司 | 抗介白素-33抗體及其用途 |
| CN107109494B (zh) | 2014-11-10 | 2023-10-27 | 豪夫迈·罗氏有限公司 | Il-33介导型疾病的治疗方法和诊断方法 |
| JP7114460B2 (ja) | 2015-06-26 | 2022-08-08 | サノフィ・バイオテクノロジー | モノクローナル抗ＩＬ－１ＲＡｃＰ抗体 |
| WO2017181790A1 (zh) * | 2016-04-19 | 2017-10-26 | 南京中硼联康医疗科技有限公司 | 用于消除β淀粉样蛋白沉积斑块的中子捕获治疗系统 |
| EP3241845A1 (en) * | 2016-05-06 | 2017-11-08 | MAB Discovery GmbH | Humanized anti-il-1r3 antibodies |
| CA3084459A1 (en) | 2016-10-16 | 2018-04-19 | Cellerant Therapeutics, Inc. | Anti-il1-rap antibodies |
| EP3548515B1 (en) | 2016-12-01 | 2026-01-21 | Regeneron Pharmaceuticals, Inc. | Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging |
| CA3053348A1 (en) | 2017-02-10 | 2018-08-16 | Regeneron Pharmaceuticals, Inc. | Radiolabeled anti-lag3 antibodies for immuno-pet imaging |
| EP3401332A1 (en) * | 2017-05-08 | 2018-11-14 | MAB Discovery GmbH | Anti-il-1r3 antibodies for use in inflammatory conditions |
| CA3066918A1 (en) * | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| KR102880156B1 (ko) | 2017-07-24 | 2025-11-05 | 리제너론 파마슈티칼스 인코포레이티드 | 항cd8 항체 및 이의 용도 |
| KR20200038490A (ko) * | 2017-08-01 | 2020-04-13 | 시티 오브 호프 | 항-il1rap 항체 |
| EP3489259A1 (en) * | 2017-11-23 | 2019-05-29 | Etablissement Français du Sang | Anti-il-1rap-car-t cells and their use |
| CA3091047A1 (en) * | 2018-02-14 | 2019-08-22 | Yale University | Compositions for modulation of a trem or treml protein and methods of use |
| US12209131B2 (en) * | 2018-08-16 | 2025-01-28 | Cantargia Ab | Anti-IL1RAP antibody compositions |
| TW202021618A (zh) | 2018-08-17 | 2020-06-16 | 美商２３與我有限公司 | 抗ｉｌ１ｒａｐ抗體及其使用方法 |
| CN113710229B (zh) | 2019-02-25 | 2026-01-06 | 芝加哥大学 | 用与抗炎剂连接的ecm亲和肽治疗炎症性和自身免疫性病症的方法和组合物 |
| US11896682B2 (en) | 2019-09-16 | 2024-02-13 | Regeneron Pharmaceuticals, Inc. | Radiolabeled MET binding proteins for immuno-PET imaging and methods of use thereof |
| WO2021148884A1 (en) * | 2020-01-24 | 2021-07-29 | Tychan Pte. Ltd. | Anti-wuhan coronavirus antibodies |
| AU2021236306A1 (en) | 2020-03-13 | 2022-09-15 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| WO2021207709A1 (en) * | 2020-04-10 | 2021-10-14 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Binders and chimeric antigen receptors specific for interleukin-1 receptor accessory protein |
| US11970539B2 (en) | 2020-09-14 | 2024-04-30 | Ichnos Sciences SA | Antibodies that bind to IL1RAP and uses thereof |
| AR124414A1 (es) | 2020-12-18 | 2023-03-22 | Century Therapeutics Inc | Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable |
| JP2024520338A (ja) | 2021-05-21 | 2024-05-24 | レオ ファーマ アクティーゼルスカブ | 抗ｉｌ－１受容体アクセサリータンパク質抗体 |
| IL317811A (en) | 2022-07-25 | 2025-02-01 | Interius Biotherapeutics Inc | Mutated polypeptides, compositions containing them and uses thereof |
| AU2023345467A1 (en) | 2022-09-21 | 2025-05-08 | Sanofi Biotechnology | Humanized anti-il-1r3 antibody and methods of use |
| CN120813608A (zh) * | 2023-02-09 | 2025-10-17 | 希望之城公司 | 抗il1rap抗体及其变体 |
| CN120882427A (zh) * | 2023-03-24 | 2025-10-31 | 派拉冈医疗公司 | 结合FcRn的Fc片段和使用方法 |
| TW202530255A (zh) * | 2023-12-15 | 2025-08-01 | 法商亞維西亞有限公司 | 抗ｉｌ－１ｒａｐ結合結構域及其抗體－藥物偶聯物 |
| WO2025201513A1 (zh) * | 2024-03-29 | 2025-10-02 | 珠海丹序生物制药有限公司 | 抗il1rap抗体及其用途 |
| WO2026022232A1 (en) | 2024-07-24 | 2026-01-29 | Almirall, S.A. | Il-1rap inhibitor for treating or preventing hidradenitis suppurativa |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| SE459005B (sv) | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | Saett att framstaella sfaeriska polymerpartiklar |
| PE64396A1 (es) | 1995-01-23 | 1997-01-28 | Hoffmann La Roche | Proteina accesoria del receptor de la interleucina 1 |
| CA2192782C (en) | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
| US20030215453A1 (en) | 2002-05-14 | 2003-11-20 | Dedera Douglas A. | Methods of therapy and diagnosis using immunotargeting of cells expressing VpreB1 protein |
| US7960512B2 (en) | 2003-01-09 | 2011-06-14 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
| EP1639090A4 (en) | 2003-06-09 | 2008-04-16 | Univ Michigan | COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER |
| GB0316294D0 (en) | 2003-07-11 | 2003-08-13 | Polytherics Ltd | Conjugated biological molecules and their preparation |
| PL1776384T3 (pl) | 2004-08-04 | 2013-10-31 | Mentrik Biotech Llc | WARIANTY REGIONÓW Fc |
| CA2965198C (en) | 2008-01-15 | 2021-02-16 | The Board Of Trustees Of The Leland Stanford Junior University | Markers of acute myeloid leukemia stem cells |
| JP2011515497A (ja) | 2008-03-26 | 2011-05-19 | セレラント セラピューティクス インコーポレイテッド | 骨髄性血液学的増殖性疾患と関連する免疫グロブリンおよび／またはＴｏｌｌ様受容体タンパク質ならびにその使用 |
| GB2472856B (en) | 2009-08-21 | 2012-07-11 | Cantargia Ab | IL1-RAP modulators and uses thereof |
| RU2597831C2 (ru) * | 2011-01-19 | 2016-09-20 | Кантаргия Аб | Анти-il1rap антитела и их применение при лечении людей |
| CN103077969B (zh) | 2011-10-26 | 2016-03-30 | 中国科学院微电子研究所 | 一种mos器件及其制造方法 |
| JP7114460B2 (ja) | 2015-06-26 | 2022-08-08 | サノフィ・バイオテクノロジー | モノクローナル抗ＩＬ－１ＲＡｃＰ抗体 |
| AU2016350705A1 (en) | 2015-11-02 | 2018-05-17 | Janssen Pharmaceutica Nv | Anti-IL1RAP antibodies, bispecific antigen binding molecules that bind IL1RAP and CD3, and uses thereof |
-
2014
- 2014-08-06 GB GBGB1413913.3A patent/GB201413913D0/en not_active Ceased
-
2015
- 2015-08-06 JP JP2017506267A patent/JP6827411B2/ja active Active
- 2015-08-06 WO PCT/EP2015/068208 patent/WO2016020502A1/en not_active Ceased
- 2015-08-06 US US15/501,710 patent/US10100119B2/en active Active
- 2015-08-06 MX MX2017001599A patent/MX2017001599A/es unknown
- 2015-08-06 CA CA2955056A patent/CA2955056A1/en not_active Abandoned
- 2015-08-06 EP EP15747487.5A patent/EP3193926B1/en active Active
- 2015-08-06 BR BR112017002342-3A patent/BR112017002342A2/en not_active Application Discontinuation
- 2015-08-06 CN CN201580042011.9A patent/CN107074946B/zh active Active
- 2015-08-06 AU AU2015298852A patent/AU2015298852A1/en not_active Abandoned
- 2015-08-06 KR KR1020177004417A patent/KR20170039685A/ko not_active Withdrawn
-
2018
- 2018-08-22 US US16/109,017 patent/US10562971B2/en active Active
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