JP2019526628A - セニクリビロクメシレートの固体形態及びセニクリビロクメシレートの固体形態を製造するプロセス - Google Patents

セニクリビロクメシレートの固体形態及びセニクリビロクメシレートの固体形態を製造するプロセス Download PDF

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JP2019526628A
JP2019526628A JP2019531594A JP2019531594A JP2019526628A JP 2019526628 A JP2019526628 A JP 2019526628A JP 2019531594 A JP2019531594 A JP 2019531594A JP 2019531594 A JP2019531594 A JP 2019531594A JP 2019526628 A JP2019526628 A JP 2019526628A
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Prior art keywords
crystalline form
compound
msoh
acetonitrile
ethyl acetate
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Japanese (ja)
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JP2019526628A5 (enExample
Inventor
パシット・フィアシヴォンサ
マーティン・イアン・クーパー
エマ・ケイ・シャープ
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トビラ セラピューティクス， インコーポレイテッド
トビラ セラピューティクス， インコーポレイテッド
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Publication of JP2019526628A publication Critical patent/JP2019526628A/ja
Publication of JP2019526628A5 publication Critical patent/JP2019526628A5/ja
Priority to JP2022113230A priority Critical patent/JP2022137223A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019531594A 2016-08-31 2017-08-30 セニクリビロクメシレートの固体形態及びセニクリビロクメシレートの固体形態を製造するプロセス Pending JP2019526628A (ja)

Priority Applications (1)

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JP2022113230A JP2022137223A (ja) 2016-08-31 2022-07-14 セニクリビロクメシレートの固体形態及びセニクリビロクメシレートの固体形態を製造するプロセス

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662382153P 2016-08-31 2016-08-31
US62/382,153 2016-08-31
PCT/US2017/049400 WO2018045043A1 (en) 2016-08-31 2017-08-30 Solid forms of cenicriviroc mesylate and processes of making solid forms of cenicriviroc mesylate

Related Child Applications (1)

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JP2022113230A Division JP2022137223A (ja) 2016-08-31 2022-07-14 セニクリビロクメシレートの固体形態及びセニクリビロクメシレートの固体形態を製造するプロセス

Publications (2)

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JP2019526628A true JP2019526628A (ja) 2019-09-19
JP2019526628A5 JP2019526628A5 (enExample) 2020-10-08

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JP2019531594A Pending JP2019526628A (ja) 2016-08-31 2017-08-30 セニクリビロクメシレートの固体形態及びセニクリビロクメシレートの固体形態を製造するプロセス
JP2022113230A Pending JP2022137223A (ja) 2016-08-31 2022-07-14 セニクリビロクメシレートの固体形態及びセニクリビロクメシレートの固体形態を製造するプロセス

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JP2022113230A Pending JP2022137223A (ja) 2016-08-31 2022-07-14 セニクリビロクメシレートの固体形態及びセニクリビロクメシレートの固体形態を製造するプロセス

Country Status (13)

Country Link
US (1) US10301287B2 (enExample)
EP (1) EP3506896A4 (enExample)
JP (2) JP2019526628A (enExample)
KR (1) KR20190057066A (enExample)
CN (1) CN110167550A (enExample)
AU (1) AU2017321594A1 (enExample)
BR (1) BR112019003987A2 (enExample)
CA (1) CA3034606A1 (enExample)
MX (1) MX2019002057A (enExample)
RU (1) RU2019109019A (enExample)
SG (1) SG11201901438VA (enExample)
TW (1) TW201823235A (enExample)
WO (1) WO2018045043A1 (enExample)

Cited By (1)

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JPWO2022177014A1 (enExample) * 2021-02-22 2022-08-25

Families Citing this family (9)

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WO2019238041A1 (zh) * 2018-06-12 2019-12-19 南京明德新药研发有限公司 一种丙烯酰胺类化合物的晶型及其制备方法
WO2019245517A1 (en) * 2018-06-18 2019-12-26 Hewlett-Packard Development Company, L.P. Three-dimensional printing
US11613670B2 (en) 2018-06-18 2023-03-28 Hewlett-Packard Development Company, L.P. Three-dimensional printing
US11591486B2 (en) 2018-06-19 2023-02-28 Hewlett-Packard Development Company, L.P. Three-dimensional printing
WO2019245589A1 (en) 2018-06-19 2019-12-26 Hewlett-Packard Development Company, L.P. Three-dimensional printing
WO2019245534A1 (en) * 2018-06-19 2019-12-26 Hewlett-Packard Development Company, L.P. Three-dimensional printing
KR20210053921A (ko) * 2018-08-31 2021-05-12 에보니크 오퍼레이션즈 게엠베하 중합체 분말을 제조하는 방법
WO2021133811A1 (en) 2019-12-26 2021-07-01 Teva Pharmaceuticals International Gmbh Solid state forms of cenicriviroc and process for preparation thereof
EP4159730A4 (en) 2020-05-22 2024-05-01 Medshine Discovery Inc. PYRIDINE DERIVATIVE AND APPLICATION THEREOF

Citations (4)

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JP2004123694A (ja) * 2002-03-12 2004-04-22 Takeda Chem Ind Ltd 光学活性スルホキシド誘導体の製造法
JP2007269628A (ja) * 2004-05-28 2007-10-18 Takeda Chem Ind Ltd 医薬化合物の結晶
JP2013136629A (ja) * 2001-08-08 2013-07-11 Tobira Therapeutics Inc 二環性化合物、その製造法および用途
WO2016105527A1 (en) * 2014-12-23 2016-06-30 Tobira Therapeutics, Inc. Process of making cenicriviroc and related analogs

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JPS62265270A (ja) 1986-05-13 1987-11-18 Zeria Shinyaku Kogyo Kk 新規イミダゾ−ル誘導体およびそれらを有効成分とする抗潰瘍剤
AU2808495A (en) 1994-07-04 1996-01-25 Takeda Chemical Industries Ltd. Phosphonic acid compounds, their production and use
WO1999032100A2 (en) 1997-12-19 1999-07-01 Takeda Chemical Industries, Ltd. Pharmaceutical composition for antagonizing ccr5 comprising anilide derivative
EP1104416A2 (en) 1998-08-20 2001-06-06 Takeda Chemical Industries, Ltd. Quaternary ammonium salts and their use as anti-hiv agents
CA2384145A1 (en) 1999-09-06 2001-03-15 Takeda Chemical Industries, Ltd. Process for the preparation of 2,3-dihydroazepine compounds
EP1728504B1 (en) 2004-03-24 2013-07-31 Takeda Pharmaceutical Company Limited Emulsion stabilizer
GT200600148A (es) 2005-04-14 2006-11-22 Metodos para el tratamiento y la prevencion de fibrosis
CA2818308A1 (en) 2010-11-18 2012-05-24 Yale University Bifunctional molecules with antibody-recruiting and entry inhibitory activity against the human immunodeficiency virus
AU2013257951A1 (en) 2012-05-11 2015-01-22 Akron Molecules Ag Use of compounds for the treatment of pain
KR20160013068A (ko) 2013-05-15 2016-02-03 토비라 쎄라퓨틱스, 인크. 세니크리비록 조성물 및 이들을 만들고 이용하는 방법
CA2941411A1 (en) * 2014-03-21 2015-09-24 Tobira Therapeutics, Inc. Cenicriviroc for the treatment of fibrosis
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JP2013136629A (ja) * 2001-08-08 2013-07-11 Tobira Therapeutics Inc 二環性化合物、その製造法および用途
JP2004123694A (ja) * 2002-03-12 2004-04-22 Takeda Chem Ind Ltd 光学活性スルホキシド誘導体の製造法
JP2007269628A (ja) * 2004-05-28 2007-10-18 Takeda Chem Ind Ltd 医薬化合物の結晶
WO2016105527A1 (en) * 2014-12-23 2016-06-30 Tobira Therapeutics, Inc. Process of making cenicriviroc and related analogs

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高田則幸: "創薬段階における原薬Formスクリーニングと選択", PHARM STAGE, vol. 6, no. 10, JPN6009053755, 15 January 2007 (2007-01-15), pages 20 - 25, ISSN: 0004727167 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2022177014A1 (enExample) * 2021-02-22 2022-08-25
JP7374372B2 (ja) 2021-02-22 2023-11-06 旭化成株式会社 セルロースナノファイバーを含む組成物

Also Published As

Publication number Publication date
JP2022137223A (ja) 2022-09-21
RU2019109019A3 (enExample) 2021-08-23
WO2018045043A1 (en) 2018-03-08
RU2019109019A (ru) 2020-10-01
US20180057481A1 (en) 2018-03-01
SG11201901438VA (en) 2019-03-28
TW201823235A (zh) 2018-07-01
CN110167550A (zh) 2019-08-23
KR20190057066A (ko) 2019-05-27
AU2017321594A1 (en) 2019-04-18
US10301287B2 (en) 2019-05-28
BR112019003987A2 (pt) 2019-05-28
EP3506896A1 (en) 2019-07-10
MX2019002057A (es) 2019-11-18
EP3506896A4 (en) 2020-08-26
CA3034606A1 (en) 2018-03-08

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