JP2019524772A - ５−コレステン−３，２５−ジオール，３−サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物 - Google Patents

５−コレステン−３，２５−ジオール，３−サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物 Download PDF

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JP2019524772A
JP2019524772A JP2019505229A JP2019505229A JP2019524772A JP 2019524772 A JP2019524772 A JP 2019524772A JP 2019505229 A JP2019505229 A JP 2019505229A JP 2019505229 A JP2019505229 A JP 2019505229A JP 2019524772 A JP2019524772 A JP 2019524772A
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Prior art keywords
25hc3s
composition
cyclodextrin
disease
liver
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JP2019505229A
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Japanese (ja)
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JP2019524772A5 (cg-RX-API-DMAC7.html
Inventor
レン，シュンリン
スー，レユアン
ニン，ヤンシア
キム，ジン，コウン
リン，ウェイチー
ジーン キム，ミー
ジーン キム，ミー
ミクスズタル，アンドリュー，アール．
ウー，ホンウェイ
リー，ミン，エル．
タムラズ，ウィルマ
Original Assignee
ヴァージニア コモンウェルス ユニバーシティ
ヴァージニア コモンウェルス ユニバーシティ
デュレクト コーポレーション
デュレクト コーポレーション
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Application filed by ヴァージニア コモンウェルス ユニバーシティ, ヴァージニア コモンウェルス ユニバーシティ, デュレクト コーポレーション, デュレクト コーポレーション filed Critical ヴァージニア コモンウェルス ユニバーシティ
Publication of JP2019524772A publication Critical patent/JP2019524772A/ja
Publication of JP2019524772A5 publication Critical patent/JP2019524772A5/ja
Priority to JP2022122494A priority Critical patent/JP7487264B2/ja
Priority to JP2024075682A priority patent/JP2024105442A/ja
Pending legal-status Critical Current

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
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  • Dispersion Chemistry (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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JP2019505229A 2016-08-02 2017-08-01 ５−コレステン−３，２５−ジオール，３−サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物 Pending JP2019524772A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022122494A JP7487264B2 (ja) 2016-08-02 2022-08-01 ５－コレステン－３，２５－ジオール，３－サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物
JP2024075682A JP2024105442A (ja) 2016-08-02 2024-05-08 ５－コレステン－３，２５－ジオール，３－サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662370024P 2016-08-02 2016-08-02
US62/370,024 2016-08-02
US201762470578P 2017-03-13 2017-03-13
US62/470,578 2017-03-13
PCT/US2017/044840 WO2018026781A1 (en) 2016-08-02 2017-08-01 Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25hc3s) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide

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JP2022122494A Division JP7487264B2 (ja) 2016-08-02 2022-08-01 ５－コレステン－３，２５－ジオール，３－サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物

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JP2019524772A true JP2019524772A (ja) 2019-09-05
JP2019524772A5 JP2019524772A5 (cg-RX-API-DMAC7.html) 2020-08-20

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JP2019505229A Pending JP2019524772A (ja) 2016-08-02 2017-08-01 ５−コレステン−３，２５−ジオール，３−サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物
JP2022122494A Active JP7487264B2 (ja) 2016-08-02 2022-08-01 ５－コレステン－３，２５－ジオール，３－サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物
JP2024075682A Pending JP2024105442A (ja) 2016-08-02 2024-05-08 ５－コレステン－３，２５－ジオール，３－サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物

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JP2022122494A Active JP7487264B2 (ja) 2016-08-02 2022-08-01 ５－コレステン－３，２５－ジオール，３－サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物
JP2024075682A Pending JP2024105442A (ja) 2016-08-02 2024-05-08 ５－コレステン－３，２５－ジオール，３－サルフェート（２５ｈｃ３ｓ）又は薬学的に許容される塩及び少なくとも１種の環状オリゴ糖を含む組成物

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US (4) US20190269695A1 (cg-RX-API-DMAC7.html)
EP (2) EP4101861A1 (cg-RX-API-DMAC7.html)
JP (3) JP2019524772A (cg-RX-API-DMAC7.html)
KR (3) KR102593667B1 (cg-RX-API-DMAC7.html)
CN (2) CN109983025B (cg-RX-API-DMAC7.html)
AU (2) AU2017305239C1 (cg-RX-API-DMAC7.html)
CA (1) CA3031224A1 (cg-RX-API-DMAC7.html)
DK (1) DK3494125T3 (cg-RX-API-DMAC7.html)
EA (1) EA201990438A1 (cg-RX-API-DMAC7.html)
ES (1) ES2922933T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20220932T1 (cg-RX-API-DMAC7.html)
HU (1) HUE059768T2 (cg-RX-API-DMAC7.html)
IL (2) IL298681A (cg-RX-API-DMAC7.html)
LT (1) LT3494125T (cg-RX-API-DMAC7.html)
MX (2) MX2019001323A (cg-RX-API-DMAC7.html)
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PT (1) PT3494125T (cg-RX-API-DMAC7.html)
RS (1) RS63529B1 (cg-RX-API-DMAC7.html)
SI (1) SI3494125T1 (cg-RX-API-DMAC7.html)
SM (1) SMT202200330T1 (cg-RX-API-DMAC7.html)
TW (2) TW202426000A (cg-RX-API-DMAC7.html)
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Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006047022A1 (en) 2004-10-25 2006-05-04 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis
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KR102593667B1 (ko) 2016-08-02 2023-10-24 버지니아 커먼웰스 유니버시티 5-콜레스텐-3, 25-디올, 3-술페이트 (25hc3s) 또는 이의 약학적으로 허용 가능한 염, 및 적어도 하나의 시클릭 올리고당을 포함하는 조성물
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