SI3494125T1 - Sestavki, ki vsebujejo 5-holesten-3, 25-diol, 3-sulfat(25HC3S) ali njegovo farmacevtsko sprejemljivo sol in vsaj en cikličen oligosaharid - Google Patents

Sestavki, ki vsebujejo 5-holesten-3, 25-diol, 3-sulfat(25HC3S) ali njegovo farmacevtsko sprejemljivo sol in vsaj en cikličen oligosaharid

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Publication number
SI3494125T1
SI3494125T1 SI201731214T SI201731214T SI3494125T1 SI 3494125 T1 SI3494125 T1 SI 3494125T1 SI 201731214 T SI201731214 T SI 201731214T SI 201731214 T SI201731214 T SI 201731214T SI 3494125 T1 SI3494125 T1 SI 3494125T1
Authority
SI
Slovenia
Prior art keywords
25hc3s
cholesten
diol
sulfate
compositions
Prior art date
Application number
SI201731214T
Other languages
English (en)
Inventor
Shunlin Ren
Leyuan Xu
Yanxia Ning
Jin Koung Kim
Weiqi Lin
Meej Kim
Andrew R. Miksztal
Hongwei Wu
Min L. Lee
Wilma Tamraz
Original Assignee
Virginia Commonwealth University
The United States Government As Represented By The Department Of Veterans Affairs
Durect Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virginia Commonwealth University, The United States Government As Represented By The Department Of Veterans Affairs, Durect Corporation filed Critical Virginia Commonwealth University
Publication of SI3494125T1 publication Critical patent/SI3494125T1/sl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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    • A61K31/716—Glucans
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
SI201731214T 2016-08-02 2017-08-01 Sestavki, ki vsebujejo 5-holesten-3, 25-diol, 3-sulfat(25HC3S) ali njegovo farmacevtsko sprejemljivo sol in vsaj en cikličen oligosaharid SI3494125T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662370024P 2016-08-02 2016-08-02
US201762470578P 2017-03-13 2017-03-13
PCT/US2017/044840 WO2018026781A1 (en) 2016-08-02 2017-08-01 Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25hc3s) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide
EP17837516.8A EP3494125B1 (en) 2016-08-02 2017-08-01 Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25hc3s) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide

Publications (1)

Publication Number Publication Date
SI3494125T1 true SI3494125T1 (sl) 2022-10-28

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SI201731214T SI3494125T1 (sl) 2016-08-02 2017-08-01 Sestavki, ki vsebujejo 5-holesten-3, 25-diol, 3-sulfat(25HC3S) ali njegovo farmacevtsko sprejemljivo sol in vsaj en cikličen oligosaharid

Country Status (21)

Country Link
US (3) US20190269695A1 (sl)
EP (2) EP4101861A1 (sl)
JP (2) JP2019524772A (sl)
KR (3) KR102465046B1 (sl)
CN (2) CN116747233A (sl)
AU (2) AU2017305239C1 (sl)
CA (1) CA3031224A1 (sl)
DK (1) DK3494125T3 (sl)
EA (1) EA201990438A1 (sl)
ES (1) ES2922933T3 (sl)
HR (1) HRP20220932T1 (sl)
HU (1) HUE059768T2 (sl)
IL (2) IL298681A (sl)
LT (1) LT3494125T (sl)
MX (2) MX2019001323A (sl)
PL (1) PL3494125T3 (sl)
PT (1) PT3494125T (sl)
RS (1) RS63529B1 (sl)
SI (1) SI3494125T1 (sl)
TW (1) TWI815796B (sl)
WO (1) WO2018026781A1 (sl)

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CN114555044A (zh) * 2019-09-30 2022-05-27 度勒科特公司 酒精性肝炎的治疗
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US20230130325A1 (en) * 2020-03-31 2023-04-27 The Regents Of The University Of Michigan Serum metabolites as biomarkers for carnitine treatment of sepsis
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