JP2019524720A5 - - Google Patents
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- Publication number
- JP2019524720A5 JP2019524720A5 JP2019500809A JP2019500809A JP2019524720A5 JP 2019524720 A5 JP2019524720 A5 JP 2019524720A5 JP 2019500809 A JP2019500809 A JP 2019500809A JP 2019500809 A JP2019500809 A JP 2019500809A JP 2019524720 A5 JP2019524720 A5 JP 2019524720A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- triazole
- alkyl
- optionally
- deoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16179060 | 2016-07-12 | ||
| EP16179060.5 | 2016-07-12 | ||
| PCT/EP2017/067180 WO2018011093A1 (en) | 2016-07-12 | 2017-07-09 | Alpha-d-galactoside inhibitors of galectins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019524720A JP2019524720A (ja) | 2019-09-05 |
| JP2019524720A5 true JP2019524720A5 (https=) | 2021-11-04 |
| JP7038099B2 JP7038099B2 (ja) | 2022-03-17 |
Family
ID=56411454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019500809A Expired - Fee Related JP7038099B2 (ja) | 2016-07-12 | 2017-07-09 | ガレクチンのα－Ｄ－ガラクトシド阻害剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10988502B2 (https=) |
| EP (1) | EP3484903A1 (https=) |
| JP (1) | JP7038099B2 (https=) |
| CN (1) | CN109563120B (https=) |
| CA (1) | CA3025866A1 (https=) |
| WO (1) | WO2018011093A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6904906B2 (ja) * | 2015-01-30 | 2021-07-21 | ガレクト・バイオテック・エイビイ | ガレクチンの新規なガラクトシド阻害剤 |
| CA3025867A1 (en) * | 2016-07-12 | 2018-01-18 | Galecto Biotech Ab | Alpha-d-galactoside inhibitors of galectins |
| US11046725B2 (en) | 2018-01-10 | 2021-06-29 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| WO2019146773A1 (ja) * | 2018-01-25 | 2019-08-01 | 株式会社フジモト・コーポレーション | チオフェン誘導体およびその用途 |
| US20210138080A1 (en) | 2018-06-29 | 2021-05-13 | Glykos Biomedical Oy | Conjugates |
| JP2022508719A (ja) * | 2018-10-15 | 2022-01-19 | ガレクト バイオテック エービー | ガレクチンのガラクトシド阻害剤のプロドラッグ |
| CN113366007A (zh) * | 2018-10-15 | 2021-09-07 | 格莱克特生物技术公司 | 半乳糖凝集素的半乳糖苷抑制剂 |
| JP7486484B2 (ja) * | 2018-11-21 | 2024-05-17 | ガレクト バイオテック エービー | ガレクチンのα－Ｄ－ガラクトシド阻害剤 |
| EP3983423A4 (en) | 2019-06-14 | 2023-07-19 | Université Laval | SYNTHESIS OF 3-AZIDO-3-DEOXY-D-GALACTOPYRANOSE |
| CA3141436A1 (en) * | 2019-07-03 | 2021-01-07 | Fredrik Zetterberg | Novel galactoside inhibitor of galectins |
| CN114514235A (zh) * | 2019-07-03 | 2022-05-17 | 格莱克特生物技术公司 | 半乳糖凝集素的新型半乳糖苷抑制剂 |
| US20230038373A1 (en) | 2019-12-18 | 2023-02-09 | Glykos Biomedical Oy | Stabile conjugate |
| CA3161794A1 (en) * | 2019-12-24 | 2021-07-01 | John L. Magnani | Galectin-3 inhibiting c-glycoside ketones, ethers, and alcohols |
| CN113943330A (zh) * | 2020-07-17 | 2022-01-18 | 中国科学院上海药物研究所 | 一类含糖结构化合物、其制备方法、药物组合物和用途 |
| CN116745286A (zh) * | 2020-12-22 | 2023-09-12 | 格莱克特生物技术公司 | 半乳糖凝集素的新型半乳糖苷抑制剂 |
| CN117043156A (zh) * | 2020-12-28 | 2023-11-10 | 格莱克特生物技术公司 | 半乳糖凝集素的新型半乳糖苷抑制剂 |
| CZ2023132A3 (cs) * | 2023-04-04 | 2024-10-16 | Ústav Chemických Procesů Av Čr, V. V. I. | Komplexy ruthenia pro inhibici galektinů, způsob jejich výroby a jejich použití |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060148712A1 (en) | 2000-03-13 | 2006-07-06 | Fu-Tong Liu | Monocyte chemoattractant activity of galectin-3 |
| US6849607B2 (en) | 2001-05-09 | 2005-02-01 | Health Research, Inc. | Galectin recognized photosensitizers for photodynamic therapy |
| SE0401301D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel 3-triazolyl-galactoside inhibitors of galectins |
| SE0401300D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel Galactoside Inhibitors of Galectins |
| CN102439021B (zh) | 2009-04-28 | 2015-09-02 | 格莱克特生物技术公司 | 半乳凝素的新型半乳糖苷抑制剂 |
| EP2620443A1 (en) * | 2012-01-25 | 2013-07-31 | Galecto Biotech AB | Novel galactoside inhibitors of galectins |
| US8828971B2 (en) | 2012-10-10 | 2014-09-09 | Galectin Therapeutics, Inc. | Galactose-pronged carbohydrate compounds for the treatment of diabetic nephropathy and associated disorders |
| JP2015535233A (ja) * | 2012-10-31 | 2015-12-10 | ガレクト・バイオテック・エイビイ | ガレクチン−３のガラクトシド阻害剤及び肺線維症のためのその使用 |
| WO2014078655A1 (en) | 2012-11-15 | 2014-05-22 | Tufts University | Methods, compositions and kits for treating, modulating, or preventing ocular angiogenesis or fibrosis in a subject using a galectin protein inhibitor |
| JP6904906B2 (ja) * | 2015-01-30 | 2021-07-21 | ガレクト・バイオテック・エイビイ | ガレクチンの新規なガラクトシド阻害剤 |
| CA3025867A1 (en) | 2016-07-12 | 2018-01-18 | Galecto Biotech Ab | Alpha-d-galactoside inhibitors of galectins |
-
2017
- 2017-07-09 WO PCT/EP2017/067180 patent/WO2018011093A1/en not_active Ceased
- 2017-07-09 JP JP2019500809A patent/JP7038099B2/ja not_active Expired - Fee Related
- 2017-07-09 CN CN201780042826.6A patent/CN109563120B/zh not_active Expired - Fee Related
- 2017-07-09 US US16/313,625 patent/US10988502B2/en active Active
- 2017-07-09 CA CA3025866A patent/CA3025866A1/en active Pending
- 2017-07-09 EP EP17735568.2A patent/EP3484903A1/en not_active Withdrawn
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